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EVALUATION OF THREE SUSTAINABLE SOLUTIONS FOR EXTENDING THE SHELF LIFE OF BEEF BURGERS UNDER MODIFIED ATMOSPHERE AT 4°C
No full textRaman microscopy unveils polystyrene nanoparticles in zebrafish and their role in ocular stress
No full textEffect of microencapsulation by spray drying on the protein content of Spirulina (Arthrospira platensis)
No full textNowadays, there is a great demand for sustainable and nutritious foods, and fresh spirulina is a highly valuable source of protein. However, its use is limited because of its sensitivity to environmental stress conditions and distinctive flavor. Nevertheless, microencapsulation offers an effective solution to enhance stability and mask undesirable sensory properties. This study optimized Spirulina microencapsulation via spray drying, employing maltodextrin (MD) as the coating agent. By factorial design, inlet temperature (160–180°C) and Spirulina:MD ratios (1:2–1:4) were evaluated, identifying optimal conditions (174.7°C, 1:4 ratio) that achieved 46% yield and 31.65% protein content while preserving its native amino acid profile
Next-Generation 3D Tendon Organoid: A Functional In Vitro Model for Studying Tendon Regeneration and Healing Mechanisms
No full textExploring morphological aspects, cuticle size and volatile compounds in the fruits of four olive cultivars as possibly interdependent components of Bactrocera oleae tolerance
No full textOlea europaea L. subsp. europaea, var. europaea, plays a crucial role in cultural identity and economic prosperity across many regions of the Mediterranean Basin. The olive fruit fly, Bactrocera oleae, represents a major global challenge to olive and olive oil production. Its larvae feed exclusively on olive fruits, causing severe crop damage and substantial economic losses. In this study, we examined four olive cultivars differing in susceptibility to B. oleae, focusing on fruit morphology (weight, maturity index, penetration resistance), cuticle characteristics, and volatile organic compound (VOC) emissions. Confocal microscopy with Nile Red staining was used to analyze cuticle structure, while VOCs were measured using proton-transfer-reaction time-of-flight mass spectrometry (PTR-ToF-MS). Thicker cuticles were associated with reduced infestation, suggesting a mechanical barrier function against oviposition or larval penetration. PTR-ToF-MS analysis revealed cultivar- and ripening stage-specific VOC emission patterns, with certain compounds potentially acting as deterrents or attractants to the olive fly. These results indicate that fruit morphology, cuticle development, and VOC profiles act as interdependent determinants of cultivar-specific tolerance to B. oleae. The integration of these physical and chemical traits provides valuable markers for breeding programs and contributes to the development of sustainable, integrated pest management strategies in olive cultivation
Processo ai briganti. La "legge Pica" e la giustizia militare nel Mezzogiorno postunitario.
No full textImproving real-time detection of laryngeal lesions in endoscopic images using a decoupled super-resolution enhanced YOLO
No full textBackground and Objective: Laryngeal Cancer (LC) constitutes approximately one third of head and neck cancers. Detecting early-stage lesions in this anatomical region is crucial for achieving a high survival rate. However, it poses significant diagnostic challenges owing to the varied appearance of lesions and the need for precise characterization for appropriate clinical management. Conventional diagnostic approaches rely heavily on endoscopic examination, which often requires expert interpretation and may be limited by subjective assessment. Deep learning (DL) approaches offer promising opportunities for automating lesion detection, but their efficacy in handling multi-modal imaging data and accurately localizing small lesions remains a subject of investigation. Furthermore, the clinical domain may largely benefit from the deployment of efficient DL methods that can ensure equitable access to advanced technologies, regardless of the availability of resources that can often be limited. In this study, a DL-based approach, named SRE-YOLO, was introduced to provide real-time assistance to less-experienced personnel during laryngeal assessment, by automatically detecting lesions at different scales from endoscopic White Light (WL) and Narrow-Band Imaging (NBI) images. Methods: During the training, the SRE-YOLO integrates a YOLOv8 nano (YOLOv8n) baseline with a Super-Resolution (SR) branch to enhance lesion detection. This last component is decoupled during inference to preserve the low computational demand of the YOLOv8n baseline. The evaluation was conducted on a multi-center dataset, encompassing diverse laryngeal pathologies and acquisition modalities. Results: The SRE-YOLO method improved the Average Precision (AP @IoU=0.5) in lesion detection by 5% with respect to the YOLOv8n baseline, while maintaining the inference speed of 58.8 Frames Per Second (FPS). Comparative analyses against state-of-the-art DL methods highlighted the efficacy of the SRE-YOLO approach in balancing detection accuracy, computational efficiency, and real-time applicability. Conclusions: This research underscores the potential of SRE-YOLO in developing efficient DL-driven decision support systems for real-time detection of laryngeal lesions at different scales from both WL and NBI endoscopic dat
Pubblicità della «proprietà» industriale e intellettuale. Molteplicità di modelli e pluralità di interessi nell’unitarietà del sistema
No full textOxygen Consumption and Carbon Budget in Groundwater-Obligate and Surface-Dwelling Diacyclops Species (Crustacea Copepoda Cyclopoida) Under Temperature Variability
No full textAnalytical quantification of the plant specific cardiac glycosides in biological fluids in a rare case of yellow oleander (Cascabela thevetia) self-poisoning in Italy
No full textYellow oleander contains digoxin-like cardiac glycosides that frequently cause intoxications in Sri Lanka and India. To date, though, no exposure has been analytically confirmed and quantitative determination of the plant specific glycosides in human biological fluids was never performed. We report an unusual case of self-poisoning in a young female in Italy who ingested 9 crushed seeds of Cascabela thevetia and was admitted to the emergency room with a 2nd degree atrio-ventricular block at the ECG. The case was managed with activated charcoal, repeated doses of anti-digoxin immune Fab and supportive care. A transient thrombocytopenia developed and resolved within a few days. Ultra-high performance liquid chromatography coupled with tandem mass spectrometry was used for the determination and quantification of thevetin A, thevetin B and peruvoside in plasma and urine. Thevetin A and thevetin B, two of the primary glycosides in the seeds, were not present in any of the samples, while detectable levels of the metabolite peruvoside were found in all biological samples on day 1 and 3. Digitoxigenin, the aglycone of thevetin B, was also identified using a semi-untargeted analysis. This is the first report of a quantitative determination of cardiac glycosides of yellow oleander in blood and urine. The finding may support very early administration of activated charcoal to possibly prevent further formation of secondary, and possibly more potent, glycosides and limit toxicity