1194 research outputs found
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Malformação de Chiari com manifestação cócleo-vestibular
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Assessing Executive Dysfunction in Neurodegenerative Disorders: A Critical Review of Brief Neuropsychological Tools
Full text linkExecutive function (EF) has been defined as a multifaceted construct that involves a variety of high-level cognitive abilities such as planning, working memory, mental flexibility, and inhibition. Being able to identify deficits in EF is important for the diagnosis and monitoring of several neurodegenerative disorders, and thus their assessment is a topic of much debate. In particular, there has been a growing interest in the development of neuropsychological screening tools that can potentially provide a reliable quick measure of EF. In this review, we critically discuss the four screening tools of EF currently available in the literature: Executive Interview-25 (EXIT 25), Frontal Assessment Battery (FAB), INECO Frontal Screening (IFS), and FRONTIER Executive Screen (FES). We first describe their features, and then evaluate their psychometric properties, the existing evidence on their neural correlates, and the empirical work that has been conducted in clinical populations. We conclude that the four screening tools generally present appropriate psychometric properties, and are sensitive to impairments in EF in several neurodegenerative conditions. However, more research will be needed mostly with respect to normative data and neural correlates, and to determine the extent to which these tools add specific information to the one provided by global cognition screening tests. More research directly comparing the available tools with each other will also be important to establish in which conditions each of them can be most useful.info:eu-repo/semantics/publishedVersio
Cannabis arteritis: ever more important to consider
Full text linkCannabis arteritis (CA) is a major and underdiagnosed cause of peripheral arterial disease in young patients. A 34-year-old man, daily smoker of 20 cigarettes and two cannabis cigarettes for 14 years, presented with a necrotic plaque of left hallux for 3 weeks. The Doppler ultrasound and angiography were compatible with severe Buerger's disease. Submitted to a revascularisation procedure and hypocoagulation with rivaroxaban. He had ceased smoking but maintained consumption of cannabis. Owing to the persistence of distal necrosis, amputation of the hallux was performed with good evolution. CA is a subtype of Buerger's disease. It is poorly known but increasingly prevalent and manifests in cannabis users regardless of tobacco use. The drug is considered at least a cofactor of the arteriopathy. The most effective treatment is cessation of consumption. Being cannabis one of the most consumed drugs, its mandatory to ask about its use in all young patients with arteriopathy.info:eu-repo/semantics/publishedVersio
The efficacy of hyperbaric oxygen therapy in the treatment of central retinal artery occlusion
Full text linkCentral retinal artery occlusion (CRAO) is an ophthalmological emergency. Various treatment modalities have been tried, but none have shown to alter natural history of the disease. Hyperoxia can restore retinal oxygenation, and favourable results were obtained with hyperbaric oxygen therapy (HBOT). We report two patients with sudden visual loss due to CRAO treated with HBOT. Case 1: a 61-year-old female, presented with CRAO in her left eye(OS). She was submitted to eight sessions of HBOT(2.4atmosphere absolute (ATA)). BCVA(Best corrected visual acuity) improved from counting fingers (CF) to 1.0 and fluorescein angiography (FA) showed a normalisation. Vascular study showed a value of 8.8% for HbA1c and ventricular extrasystoles. Case 2: a 69-year-old male presented with CRAO in his OS. Nine sessions of HBOT(2.4 ATA) were performed. Best corrected visual acuity (BCVA)improved from CF to 0.8 and the FA was normalised. Vascular study revealed an atheromatous carotid disease, and cardiac pathology. HBOT seems to be beneficial on the recovery of vision following CRAO.info:eu-repo/semantics/publishedVersio
Chronic rhinosinusitis: Correlation between the symptoms and score lund-mackay
Full text linkIntrodução: O correcto diagnóstico da rinossinusite crónica
com (RSCcP) ou sem (RSCsP) polipose implica o domínio
da anamnese e exame objectivo para, criteriosamente,
requisitar-se a tomografia computorizada dos seios-perinasais
(TC SPN)1
. Com base neste exame, Lund e Mackay sugeriram
um estadiamento imagiológico (SLM)2
de forma a quantificar
a opacificação dos SPN.
Objectivos: Verificar se existe uma correlação entre a clínica
e o SLM.
Métodos: Estudo retrospectivo controlado, de doentes com
RSCc/sP submetidos a CENS durante 2013.
Resultados: Recorrendo à regressão linear verificou-se que
cada sintoma adicional aumentava o SLM em 2,5 unidades
(IC95%:1,9-3,2). Através da regressão logística binária,
verificou-se que a presença de rinorreia (OR=29; IC95% 2-539), de prurido nasal (OR=20; IC95% 1-394) e de obstrução nasal
(OR=17; IC95% 2-133) eram factores de risco para SLM>4.
Conclusão: Existe correlação positiva entre a clínica e o SLM.info:eu-repo/semantics/publishedVersio
Transanal total mesorectal excision with triangle rules: a road map to prevent injuries
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Tuberculous Spondylitis: A Report of Different Clinical Scenarios and Literature Update
Full text linkTuberculosis is still one of the most important health problems in the world. In developed countries, the proportion of extrapulmonary tuberculosis cases is increasing. Nowadays tuberculous spondylitis, also known as Pott disease, is a rare clinical condition but can cause severe vertebral and neurological sequelae that can be prevented with an early correct diagnosis. The aim of this paper is to increase awareness of tuberculous spondylitis in modern times, describing three different cases and discussing its best diagnostic and therapeutic approach based on the current literature.info:eu-repo/semantics/publishedVersio
Allergic contact dermatitis caused by (meth)acrylates in nail cosmetic products in users and nail technicians - a 5-year study
Full text linkBACKGROUND:
The increasing use of long-lasting nail aesthetic products has led to a growing number of cases of allergic contact dermatitis (ACD) caused by (meth)acrylates in recent years.
OBJECTIVES:
To provide information on ACD caused by (meth)acrylates related to nail cosmetic products.
METHODS:
We retrospectively reviewed files of patients with ACD caused by (meth)acrylates related to nail cosmetic products, who were patch tested between January 2011 and December 2015 in 13 departments of dermatology in Portugal.
RESULTS:
Two-hundred and thirty cases of ACD caused by (meth)acrylates (55 technicians, 56 consumers, and 119 with mixed exposure) had been documented, mostly as chronic hand eczema (93%). The most common sensitizers were: 2-hydroxyethyl methacrylate (HEMA), which was positive in 90% of the tested patients, 2-hydroxypropyl methacrylate (HPMA), which was positive in 64.1%, and ethyleneglycol dimethacrylate, which was positive in 54.5%.
CONCLUSION:
HEMA and HPMA were the most frequent positive allergens. HEMA, which identified 90% of cases, can be considered to be a good screening allergen. The high number of cases of ACD caused by (meth)acrylates in nail cosmetic products certainly warrants better preventive measures at the occupational level, and specific regulation in the field of consumer safety.info:eu-repo/semantics/publishedVersio
Manifestações otorrinolaringológicas da doença de Madelung – a propósito de um caso clínico
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Intracardiac mass from Burkitt's lymphoma in an immunocompromised patient: a very rare form of presentation
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