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Implementasi Penyesuaian Obat Diabetes pada Saat Puasa Ramadan dan Pengaruhnya Terhadap Nilai HbA1c
Get PDFThis study aimed to evaluate the effect of diabetes medication adjustment during Ramadan fasting according to the recommendation of International Diabetes Federation-Diabetes and Ramadan International Alliance (IDF-DAR) to HbA1c values in type-2 diabetes mellitus patients. The study was conducted at a hospital in Jakarta, Indonesia with a cross-sectional study design involving 80 ambulatory patients with type-2 DM who fasted during Ramadan in 2016. About 60% of patients used oral
antidiabetes drug (OAD), mostly the combination of biguanide + sulfonylurea drugs (27.5%). The adjustments were made in which 56.2% was in accordance with IDF-DAR recommendations. The study showed that the HbA1c values decreased insignificantly (p = 0.082) from 8.75 ± 1.90 to 8.63 ± 1.82 after the adjustment. The appropriate drug adjustment based on IDF-DAR had a significant effect on the HbA1c value of DM patient with p-value 0.030 (p < 0.05).The discrepancy of drug use based on IDF-DAR 3.222 times greater caused uncontrolled HbA1c. The most influential variable to HbA1c value was drug type with p-value 0.006 (p < 0.05). Improper adjustment of Insulin or combination insulin-OAD caused HbA1c value 5 times greater to be uncontrolled than OA
Analisis Cemaran Daging Babi pada Bakso Sapi yang Dijual di Tanjung Priok menggunakan Real-Time Polymerase Chain Reaction (RT-PCR)
Get PDFBeef meatballs as a food favored by the people of Indonesia are prone to pork contamination because beef is relatively expensive. The mixing case certainly causes inconvenience for Muslim communities in Indonesia because pork is not halal to be consumed. However, it was necessary to analyze pork contamination in beef meatballs. Samples were taken from the Tanjung Priok area because the number of adherents who could consume pork in the area was quite significant. Three control meatballs
(100% pork, 100% beef, 50% pork) and 10 sample meatballs were analyzed using real-time polymerase chain reaction (RT-PCR) method. The DNA isolate used was mitochondrial DNA with a cytochrome B target area. The results of RT-PCR amplification in 3 control meatballs using pork primer showed 100% pork meatballs and a mixture of 50% pork resulting in an increase in the amplification curve with crossing point (CP) 22.82 and 20.03. While the results of the amplification of 10 samples of beef
meatballs using pork primers did not increase the amplification curve which showed that there was no amplified porcine DNA in the beef meatball product
