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Strategic intentions of higher education for sustainable development goals: Qualitative evidence from universities in Turkiye
No full textAlthough the literature on the role of higher education in sustainable development is extensive, a notable gap remains in universities' intentions to contribute to Sustainable Development Goals (SDGs), the contexts they pay attention to, and the measurement tools they use in different country samples. Aiming to contribute to this gap with the sample of Turkiye, a country with minimal progress on SDG reporting, this study conducts a three-tiered content analysis on 121 state universities' strategic plans. The prominent results show that universities in the country prioritize SDGs 8, 16, 9, 11, and 4, with 40% or higher proportions. Besides, there exists a lack of strategic targets set by any universities for SDGs 1, 10, 12, 14, and 17. While most universities pay attention to sustainability on institutional and societal aspects, with 45% or higher proportions, environmental concerns are determined to be low, and there exists a high diversity among the measurement tools with 12 types, with all 30% or lower proportions. The results present supportive evidence from Turkiye to the existing literature, particularly on Western countries' SDG prioritization, and thus, to the insight that the similarities and differences in SDG prioritization in different countries samples emerge from the geographical and regional affinities rather than educational levels. Finally, the need to promote and foster SDG reporting initiatives to make universities' SDG contributions more systematic and consistent appears to be a critical managerial implication for Turkish higher education
Real-world efficacy and safety data of immune checkpoint inhibitors in Turkish patients with metastatic melanoma: A Turkish oncology group retrospective study
Get PDFIn recent years, significant success has been achieved in the treatment of metastatic melanoma with the use of immune checkpoint inhibitors (ICIs), and it resulted in a remarkable increase in patient survival. However, there are only a few studies reflecting daily practice outside of clinical trials. The present study aimed to evaluate the effectiveness and safety of ICI therapy in Turkish patients with metastatic melanoma, including those with poor prognostic factors such as advanced age and brain metastasis. A retrospective analysis was conducted on 249 patients diagnosed with metastatic melanoma and treated with ICIs at 23 cancer centers in Turkey. The efficacy and safety of treatment were investigated, and prognostic factors were examined. The mean age was 59 years, and 64% of patients were male. A total of 28% had BRAF mutation. A total of 22% of the patients were >70 years of age and 26% had brain metastases. The objective response rate with ICI therapy was 37.7%. The median overall survival (OS) was 61 months (95% CI 47-74.9), and the median progression-free survival was 7 months (95% CI 5.9-8). Examining factors influencing overall survival, the difference in median OS was not statistically significant by sex and BRAF status, whereas there were statistically significant differences by age, objective response status, metastasis pattern, and presence of brain metastasis. Median OS was 35 months in patients >70 years when compared with 67 months in patients aged 70 years and younger (P=0.02). Median OS was 41 months in patients without objective response, whereas it could not be reached in patients with objective response (P<0.0001). Median OS was 35 months in patients with de novo metastatic disease compared with 78 months in patients with recurrent metastasis (P<0.0001). Moreover, median OS was 37 months in patients with brain metastasis in comparison with 67 months in patients without brain metastasis (P=0.006). Multivariate analysis revealed that absence of objective response, presence of de novo metastasis, and presence of brain metastasis were independent poor prognostic factors affecting survival. Grade 3-4 immune-related adverse effects were observed in 7.2% of patients, and treatment was discontinued due to adverse effects in 2.8% of patients. The present study demonstrated that real-world data on ICI therapy in Turkish patients with metastatic melanoma may slightly differ from the results of other studies due to Turkey's conditions. Additionally, the present study, which included non-clinical trial patients, revealed important prognostic factors
Tom Neale’nin an Island to Oneself eserinde antroposantrizm eleştirisi
No full textTom Neale’s autobiography An Island to Oneself (1966) reflects a deeply human-centred perspective that places mankind at the top of a natural hierarchy, where the environment and animals are valued only in relation to human needs. Neale’s attempt to create a liveable space on the remote island of Suwarrow demonstrates a mindset that seeks to control, reshape, and dominate the natural world. His efforts to clear the land, build a garden, fence off areas, tame animals, and eliminate species he deems threatening – such as pigs and crabs – reveal an attitude of ownership and superiority over nature. Nature and non-human beings are not treated as a valuable partner in his experience but as something to be subdued and reordered for personal benefit. The text reveals how this way of thinking, which treats the environment as a tool for human use, leads to the disruption of ecological balance. Neale’s relationship with the island mirrors a broader theoretical and philosophical context, where nature is often reduced to a resource to be managed, used, or overcome. Rather than offering a harmonious coexistence, the narrative underscores the consequences of placing human desires above the needs of the natural world, exposing the limitations and dangers of an anthropocentric worldview.Tom Neale’in otobiyografisi An Island to Oneself (1966) insanı doğa hiyerarşisinin en üstüne yerleştiren, derin bir insan merkezli bakış açısını yansıtır. Bu bakış açısında çevre ve hayvanlar yalnızca insan ihtiyaçlarıyla ilişkili oldukları ölçüde değer taşır. Neale’in ıssız Suwarrow Adası’nda yaşanabilir bir alan oluşturma çabası, doğayı kontrol altına alma, yeniden şekillendirme ve ona hükmetme düşüncesini açıkça ortaya koyar. Toprağı temizlemesi, bir bahçe kurması, alanları çitle çevirmesi, hayvanları evcilleştirmeye çalışması ve tehdit olarak gördüğü domuzlar ve yengeçler gibi türleri yok etme girişimleri, doğa üzerinde sahiplenici ve üstünlükçü bir tavrı gözler önüne serer. Doğa ve insan dışı varlıklar, onun tecrübesinde değerli bir ortak olarak değil, kişisel çıkarlar doğrultusunda boyun eğdirilmesi ve yeniden düzenlenmesi gereken unsurlar olarak ele alınır. Metin, çevreyi insanın hizmetine sunulacak bir araç gibi gören bu düşünce biçiminin, ekolojik dengenin bozulmasına yol açtığını ortaya koyar. Neale’in ada ile kurduğu ilişki, doğanın genellikle yönetilecek, kullanılacak ya da aşılacak bir kaynak olarak görüldüğü daha geniş teorik ve felsefi bir bağlamın yansımasıdır. Anlatı, insan arzularını doğanın ihtiyaçlarının önüne koymanın sonuçlarını vurgularken, insan merkezli dünya görüşünün sınırlarını ve tehlikelerini da açığa çıkarır
Effect of egg shape index on hatching performance and gender
No full textIn this study, the effects of shape index on chick length, gender, fertility rate, hatchability and hatching power in hatching eggs were investigated. The data of the study consisted of 1008 broiler hatching eggs. The data were analyzed using chi-square in the SPSS package program. As a result of the study, the best results in hatchability, embryonic deaths and fertility rates were obtained from the group where the shape index was between 72-76%. Therefore, it was concluded that the shape index in hatching eggs should be between 72-76% (normal shape) for successful incubation. In the study, it was determined that the shape index had no effect on the chick gender
Redesigning FDM Platforms for Bio-Printing Applications
Get PDFFused Deposition Modeling (FDM) is a prominent additive manufacturing technique known for its ability to provide cost-effective and fast printing solutions. FDM enables the production of computer-aided 3D designs as solid objects at macro scales with high-precision alignment while sacrificing excellent surface smoothness compared to other 3D printing techniques such as SLA (Stereolithography) and SLS (Selective Laser Sintering). Electro-Spinning (ES) is another technique for producing soft-structured nonwoven micro-scale materials, such as nanofibers. However, compared to the FDM technique, it has limited accuracy and sensitivity regarding high-precision alignment. The need for high-precision alignment of micro-scaled soft structures during the printing process raises the question of whether FDM and ES techniques can be combined. Today, the printing technique with such capability is called Melt Electro Writing (MEW), and in practice, it refers to the basic working principle on which bio-printers are based. This paper aims to examine how these two techniques can be combined affordably. Comparatively, it presents output production processes, design components, parameters, and materials used in output production. It discusses the limitations and advantages of such a hybrid platform, specifically from the perspective of engineering design and its biomedical applications
The role of governing the commons in sustainable regional development: The case of Aydın Koçarlı
No full textMeralar, ormanlar, su kaynakları, kıyı balıkçılığı gibi kullanıcılarını faydasından dışlamanın zor ve tüketiminde rekabetin olduğu mallar ortak mallardır. Devlet, aşırı kullanılması durumunda zarar göreceği varsayımına dayanarak ortak malları kendisi yönetmektedir. Amerikalı bilim insanı Elinor Ostrom, ortak malların devlet müdahalesine gerek kalmadan ya da minimum devlet müdahalesiyle insanlar tarafından sürdürülebilir bir şekilde yönetilebileceğini iddia etmekte ve çeşitli ülkelerden örnekler sunmaktadır. Bu çalışmanın amacı, bir ortak mal örneği olarak Aydın ili Koçarlı ilçesi çam fıstığı ormanlarının kamusal aktörler tarafından mı yoksa piyasa aktörleri tarafından mı yönetilmesi gerektiğini, sürdürülebilir bölgesel kalkınma perspektifinden araştırmaktır. Araştırmanın verileri, mülakat ve gözlem teknikleri ile elde edilmiş olup içerik analizine tabi tutulmuştur. Koçarlı vaka çalışmasının bulguları, ortak malların minimum devlet müdahalesiyle piyasa aktörleri tarafından yönetilebildiğini göstermektedir. Çalışmanın bulgularına dayalı olarak, ortak malların oto-regülasyonunun bölgesel kalkınmaya olumlu etkilerinin olduğu iddia edilebilir.Commons are those goods that are difficult to exclude users from their benefits and are subject to competition in their consumption, such as pastures, forests, water resources, and coastal fisheries. The government manages the commons itself based on the assumption that excessive use will cause harm. American scientist Elinor Ostrom claims that commons can be managed sustainably by people without government intervention or minimal government intervention and provides examples from various countries. This study aims to investigate whether pine nut forests in the Koçarlı district of Aydın province, as an example of a commons, should be managed by public actors or market actors from a sustainable regional development perspective. The study data were obtained through interviews and observation and subjected to content analysis. The findings of the Koçarlı case study show that market actors can manage commons with minimal government intervention. Based on the study's findings, it can be claimed that the auto-regulation of commons positively affects regional development
Applying ?-Statistical Convergence in Fuzzy Paranormed Spaces to Supply Chain Inventory Management Under Demand Shocks (DS)
No full textThis paper introduces and analyzes the concept of lambda-statistical convergence in fuzzy paranormed spaces, demonstrating its relevance to supply chain inventory management under demand shocks. We establish key relationships between generalized convergence methods and fuzzy convex analysis, showing how these results extend classical summability theory to uncertain demand environments. By exploring lambda-statistical Cauchy sequences and (V,lambda)-summability in fuzzy paranormed spaces, we provide new insights applicable to adaptive inventory optimization and decision-making in supply chains. Our findings bridge theoretical aspects of fuzzy convexity with practical convergence tools, advancing the robust modeling of demand uncertainty
Evaluating the financial credibility of third-party logistic providers through a novel frank operators-driven group decision-making model with dual hesitant linguistic q-rung orthopair fuzzy information
No full textIn the relevant literature, there is no study dealing with the financial credibility of third-party logistic providers with the help of decision-making frames. Further, there are no criteria to evaluate the third-party logistics providers' creditworthiness in practice, and decision-makers in the banks consider their judgments and experiences to assess the demand of the logistics firms. This study proposes a multi-criteria group decision-making framework through a dual hesitant linguistic q-rung orthopair fuzzy (DHLq-ROF) set to manage uncertainties more effectively and make a theoretical contribution to the academic literature. For ranking, the score function and accuracy function are defined. Additionally, some novel operational laws based on Frank t-norms and t-conorms are defined for DHLq-ROF numbers. A wide range of generalized aggregation operators, such as DHLqROF Frank weighted averaging, DHLq-ROF Frank weighted geometric, DHLq-ROF Frank generalized weighted averaging, and DHLq-ROF Frank generalized weighted geometric operators, are also investigated. Beyond that, several prominent characteristics of the proposed operators are studied. It is applied to a financial credibility problem for a multinational organization to demonstrate the introduced model's applicability. Considering the results obtained regarding the importance of the criteria, the most crucial criterion is market indebtedness, followed by fleet vehicle structure and current rate criteria, respectively. The results indicate that UPS, Kuhne & Nagel and DHL Deutsche Post are the best third-party logistic providers. The sensitivity analysis shows that the framework possesses favourable flexibility and effectiveness. Thanks to the framework's ability to produce practical solutions to challenging decision-making problems, it can be reliably preferred in engineering and other fields
Effects of boron and manganese doping on electrical poling and properties of 0.94(Bi0.5Na0.5)TiO3-0.06BaTiO3 piezoelectric ceramics
No full textUndoped, 1 mol % B 3+ doped (1B), and 1 mol% B 3+- 1 mol% Mn3+ co-doped (1B-1Mn) 0 . 94 (Bi 0.5 Na 0.5 )TiO 3- 0.06BaTiO3 (BNT-6BT) lead-free piezoelectric ceramics were produced by solid-state reaction method. Samples were shaped into disc pellets using high-purity perovskite phase powders of all compositions and were sintered at 1150 degrees C for 12 h in air. After the structural characterizations of the produced materials by using X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM), and Archimedes method, electrical property measurements were peformed for the undoped and variously doped samples. As it is a critical step for the improved piezoelectric properties, poling conditions were systematically studied in the range of 5-20 min time duration, at temperatures from room temperature (RT) up to 80 degrees C, and electric fields between 3 and 5 kV/mm. Major electrical properties were determined in terms of dielectric constant (epsilon r), dielectric loss (tans), piezoelectric coefficient (d33), maximum polarization (Pmax), remanent polarization (Pr), coercive field (EC), and maximum strain (Smax). The measured values were compared for undoped, 1B and 1B-1Mn ceramics. The highest epsilon r, d33, P max , Pr, and S max values were obtained for 1B composition after the poling process at RT. Although all other properties were greatly improved by B 3+ doping, high values of EC (26.87 kV/cm) and tans (0.0314) are considered to be detrimental for many applications. It has been observed that 1B-1Mn composition exhibited significantly reduced EC (22.73 kV/cm) and tans (0,0170) values with only a slight drop in other properties. It was also noted that Mn3+ doping increased the poling electric field and temperature, while the influence of poling time on properties was found to be quite negligible for all compositions in this study. As a result, the doping-dependent optimized poling conditions were determined for 1B-1Mn co-doped BNT-6BT lead-free piezoelectric ceramics in this study.Department of Scientific Research Projects (BAPK) of Afyon Kocatepe University, Turkey [21, FEN.BI bull; L.10]This work was supported by the Department of Scientific Research Projects (BAPK) of Afyon Kocatepe University, Turkey (project funding no. 21. FEN.BI center dot L.10)
Şanlıurfa’da Barınakta yaşayan köpeklerde dirofilaria immitis, ehrlichia canis, borrelia burgdorferi ve anaplasma spp seroprevalansının araştırılması
No full textThe aim of this study was to determine the seroprevalence of Ehrlichia canis (E.canis), Anaplasma spp, Borrelia burgdorferi (B. burgdorferi) and Dirofilaria immitis (D. immitis) in dogs living in shelters in Şanlıurfa province of Turkey. The study material consisted of 100 dogs (76 female and 24 male) living in a shelter in Şanlıurfa province. Sera obtained from blood samples were tested for qualitative detection of D. immitis antigen and antibodies to E. canis, B. burgdorferi, and Anaplasma spp with a rapid test kit working with the principle of immunochromatographic analysis. D. immitis antigen was not detected in any of the dogs. The presence of antibodies Anaplasma spp, E. canis, and B. burgdorferi was determined as 65%, 21% and 4%, respectively. The highest Anaplasma spp seropositivity was determined in the 2>3≤ years old age group, female and mixed dogs. When seropositivity was compared between age groups, sexes and breeds, the difference was found to be statistically significant (p0.05). The highest E. canis seropositivity was observed in the 2>3≤ years old age group, in females and crossbred dogs, and the difference between the sex was statistically significant (p0.05). Similarly, the highest B. burgdorferi seropositivity was detected in the 2>3≤ years old age group, in females and crossbred dogs, and the difference between the sex was statistically significant (p0.05). It was concluded that some vector-borne disease such as Anaplasmosis, Ehrlichiosis, and Lyme were seen in dogs living in shelters in Şanlıurfa province and necessary precautions should be taken to combat these diseases.Bu çalışmanın amacı, Türkiye’de Şanlıurfa yöresinde barınakta yaşayan köpeklerde Dirofilaria immitis (D. immitis), Anaplasma spp, Ehrlichia canis (E. canis), ve Borrelia burgdorferi (B. burgdorferi)’nin seroprevalansının belirlenmesidir. Çalışma materyalini Şanlıurfa’da barınakta yaşayan toplam 100 köpek (76 dişi, 24 erkek) oluşturdu. Kan örneklerinden elde edilen serumlar, D. immitis antijeni ve E. canis, B. burgdorferi ve Anaplasma spp antikorlarının kalitatif tespiti için immunokromatografik analiz prensibi ile çalışan hızlı test kiti ile test edildi. Köpeklerin hiçbirinde D. immitis antijeni belirlenmedi. Anaplasma spp, E. canis ve B. burgdorferi antikor varlığı sırasıyla %65, %21 ve %4 olarak belirlendi. Anaplasma spp seropozitiğinin en yüksek 2>3≤ yaş grubunda, dişilerde ve melezlerde olduğu belirlendi. Seropozitiflik yaş grupları, cinsiyetler ve ırklar arası karşılaştırıldığında, farkın istatistiksel olarak anlamlı olduğu bulundu (p0.05). E. canis seropozitifliğinin en yüksek 2>3≤ yaş aralığında, dişilerde ve melez köpeklerde olduğu, cinsiyetler arası farkın istatistiksel olarak önemli olduğu gözlendi (p0.05). Benzer şekilde B. burgdorferi seropozitifliğinin en yüksek 2>3≤ yaş aralığında, dişilerde ve melez köpeklerde olduğu, cinsiyetler arası farkın istatistiksel olarak önemli olduğu belirlendi (p0.05). Sonuç olarak anaplasmosis, ehrlichiosis ve lyme gibi bazı vektör kaynaklı hastalıkların Şanlıurfa’da barınakta yaşayan köpeklerde görüldüğü ve bu hastalıklarla mücadele için gerekli tedbirlerin alınması gerektiği sonucuna varıldı