173581 research outputs found
Sort by
Organ Donation with Vouchers
器官捐献与移植可以挽救患者的生命,对我国的公共卫生事业和全民健康都具有重要意义。如何建立并不断完善具有中国特色、符合中国国情的器官捐献体系,通过合理合法的政策措施鼓励个体自愿登记器官捐献,是一个亟待解决的问题。该论文从市场机制设计的角度探讨自愿器官捐献的激励政策设计问题,并首次建立了关于器官捐献的动态代际交叠模型。在这一理论框架下,作者提出一系列捐献者优先机制,并分析这些机制如何激励个体登记成为器官捐献者,从而影响社会整体捐献率以及福利。
Jaehong Kim,美国普渡大学数学博士与经济学博士、美国查普曼大学博士后,厦门大学WISE和经济学院经济学系副教授。
李梦玲,新加坡南洋理工大学数学博士,厦门大学经济学院经济学系与WISE副教授。
许梦涵,美国加利福尼亚大学洛杉矶分校经济学博士,厦门大学经济学院经济学系与WISE助理教授。【Abstract】The ever-increasing shortage of organs for transplantation has motivated many
innovative policies to promote the supply of organs. This paper proposes and analyzes a
general class of deceased organ allocation policies that assign priority on organ waiting
lists to voucher holders to promote deceased donor registration. Priority vouchers
can be obtained by self-registering for donation or through family inheritance. In an
overlapping generations framework, we find that extending the donor priority benefits
to future generations can improve the aggregate donation rate and social welfare.
In particular, giving higher priority to voucher inheritors who register for donation
is always beneficial regardless of the levels of population growth and care for future
generations. By contrast, the efficacy of granting priority to nondonors with inherited
vouchers depends on these two sociodemographic factors because of potential freeriding incentives
Fundamentals of Distribution of Relaxation Times for Electrochemical Impedance Spectroscopy
电化学阻抗谱(EIS)是一种高效的原位/非原位电化学表征技术,已在电化学能源领域得到广泛应用,如用于锂离子电池、超级电容器、燃料电池等材料及器件性能的诊断和优化. 弛豫时间分布(DRT)是一种不依赖于研究对象先验知识的EIS解析技术,可用于分离和解析EIS中高度重叠的物理化学过程. 为了促进DRT解析技术的应用和推广,本文详细阐述了如下问题: 1) DRT解析原理、实现算法及重要扩展; 2) 典型电路基元的DRT解析分析; 3) DRT的具体实现及在电化学能源中的典型应用举例; 4)DRT解析技术研究进展、存在问题及发展趋势.Electrochemical impedance spectroscopy (EIS) is a powerful electrochemical characterization technology, which has been widely used in the field of electrochemical energy, such as lithium-ion batteries, supercapacitors, fuel cells, etc. Distribution of relaxation time (DRT) is an EIS deconvolution technique which does not depend on the prior knowledge of the targeted research object. Furthermore, DRT can serve to separate and analyze physical and chemical processes which are highly overlapped in their EIS data. In order to encourage the application and popularization of DRT deconvolution technology, several core questions are addressed in this paper: (1) DRT deconvolution principle, implementation steps and important extensions; (2) DRT deconvolution method for typical circuit elements; (3) DRT implementation software and typical electrochemical energy application examples; (4) achievements, challenges and development trends for DRT deconvolution technique.西安市清洁能源重点实验室项目(2019219914SYS014CG036);国家自然科学基金(22078190)通讯作者:黄秋安,王娟,张久俊E-mail:[email protected];[email protected];[email protected]:HUANGQiu-an,WANGJuan,ZHANGJiu-junE-mail:[email protected];[email protected];[email protected].上海大学可持续能源研究院,上海 2004442.西安建筑科技大学西安市清洁能源重点实验室,陕西 西安 7100553.中国矿业大学材料科学与物理学院,江苏 徐州 2211161. Institute for Sustainable Energy, Shanghai University, Shanghai 200444, China2. Xi’an Key Laboratory of Clean Energy, Xi’an University of Architecture and Technology,Xi’an 710055, China;3. School of Materials Science and Physics, China University of Mining and Technology, Xuzhou 221116, Chin
LiCoO2 as Sulfur Host to Enhance Cathode Volumetric Capacity for Lithium-Sulfur Battery
锂-硫电池具有高的理论质量/体积能量密度,因而成为最具发展潜力的高比能二次电池体系. 然而,由于硫载体通常采用轻质的碳纳米材料,导致硫基复合材料的振实密度和体积比容量均偏低,制约了电池体积能量密度的提升. 本文尝试采用具有高密度特征的钴酸锂(LiCoO2)作为硫的载体材料,以构筑高振实密度的硫基复合材料,进而提高硫正极的体积比容量. 研究显示,LiCoO2对可溶性多硫化物具有较强的吸附作用,能够促进硫的电化学转化,因而提高了硫的活性物质利用率和循环稳定性. 同时,由于具有高的振实密度(1.90 g·cm-3),S/LiCoO2复合材料的首周体积比容量高达1750.5 mAh·cm-3,是常规硫/碳复合材料的2.2倍. 因此,本文利用具有高密度特征的LiCoO2作为硫载体来提升硫复合材料的体积比容量,有助于实现锂-硫电池的高体积能量密度.Lithium-sulfur battery is one of the most promising secondary battery systems due to its super high theoretical gravimetric and volumetric energy densities (2600 Wh·kg-1 and 2800 Wh·L-1, respectively). However, the practical volumetric capacity of sulfur cathode is still unsatisfied due to the overuse of low-density host materials, such as carbon nanomaterials. Herein, commercial LiCoO2 with the high tap density of 2.94 g·cm-3 was used as the host material to build high density sulfur-based composite and compact electrode for increasing the volumetric capacity. Obviously, the tap density of the as-prepared S/LiCoO2 composite was 1.90 g·cm-3, larger than that of the conventional S/carbon composite (0.89 g·cm-3). Correspondingly, the pressed electrode density could be increased to 2.60 g·cm-3 by using the S/LiCoO2 composite. In particular, LiCoO2 showed an effective adsorption and electrocatalytic conversion toward soluble intermediate polysulfides, and facilitied to achieve the high utilization of sulfur and cycle stability. As expected, the S/LiCoO2 composite exhibited larger capacity and slower capacity decay rate at 0.1 C rate as compared with the S/carbon composite. Meanwhile, the polarization in discharge-charge processes was smaller for the S/LiCoO2 composite, showing the enhanced reaction kinetics by adopting LiCoO2 host. Therefore, the S/LiCoO2 composite showed superior rate capability and cycle performance at large current density. By virtue of the high tap density, the S/LiCoO2 composite delivered a larger volumetric capacity (1750.5 mAh·cm-3-composite), almost 2.2 times of the S/carbon composite (811.4 mAh·cm-3-composite). Furthermore, the volumetric capacity of the pressed S/LiCoO2 electrode could reach 1676.8 mAh·cm-3-electrode based on the electrode level, almost 2.5 times of the S/carbon electrode (676.5 mAh·cm-3-electrode). This work provides a feasible strategy to achieve the high volumetric capacity and energy density of cathode based on LiCoO2 as sulfur host, which provides reference for further developing high volumetric energy density cathode materials for lithium-sulfur battery.国家自然科学基金项目(21935006)通讯作者:高学平E-mail:[email protected]:GAOXue-pingE-mail:[email protected]南开大学新能源材料化学研究所,天津 300350Institute of New Energy Material Chemistry, Nankai University, Tianjin 300350, Chin
A Study of the Institutional Advantages of Socialist Market Economy with Chinese Characteristics:Western Economics Analysis Based on the 17 Topics in Xi Jingping:The Govermance of China(Ⅱ)
牟敦果,厦门大学经济学院教授、博士生导师,经济学博士;王秋,山东省委党校(山东行政学院)副教授。【中文摘要】社会主义制度促进中国经济发展的优势有目共睹,但一些西方经济学批判者却蝇粪 点玉,极力诋毁。事实上,哈耶克等反社会主义制度的立论是有缺陷的。改革开放后中国创造经济奇迹的原因不仅在于人民的勤奋和创造力,更在于中国的制度选择,因为社会主义市场经济体制具有多方面的优势。在西方经济学框架下证明社会主义制度的优势,将是对这些西方偏颇观点的有力反驳。《习近平谈治国理政(第二卷)》的17个主题都直接或间接为推动经济发展服务。对习近平治国理政措施的要素化分析有助于构建宏观经济运行体系。基于该宏观经济运行体系和实证检验所得的变量间关系系数,构建中国宏观经济循环模型,可对比模拟检验社会主义社会经济体制和自由经济体制下的经济发展状况。分析表明,社会主义市场经济体制下经济增长目标区和灵活投资调节机制的制度安排能够保证中国经济长期稳定的发展,中国特色社会主义市场经济体制在推动中国经济持续稳定快速发展方面彰显了充分的制度自信。
【Abstract】The advantages of the socialist system in promoting China's economic development are obvious to all,but some critics in Western economics have attempted to discredit them. In fact,the anti-socialist theories of Hayek and others is flawed. China's success in creating an economic miracle since the Reform and Opening-up is due to not only the people's diligence and creativity,but also China's system choice,as the socialist market economic system has many advantages. Proving the advantages of the socialist system under the framework of Western economics will be a powerful refute to these biased views of the West. The 17 topics in Xi Jinping : The (Gvernancc ef China (Ⅱ) all serve to promote economic development directly or indirectly. By elementalizing the measures for governance, a macroeconomic operating system is constructed. Based on the macroeconomic system and coefficients between variables obtained from empirical tests,a Chinese macroeconomic simulating model is constructed,which can simulate and compare the economic development status under the socialist economic system and the free market economic system. The simulation shows that the institutional arrangements of economic growth target areas and flexible investment adjustment mechanisms under the socialist market economy system can ensure the long- term stable development of the Chinese economy. The socialist market economic system with Chinese characteristics has demonstrated the full institutional confidence in promoting the sustained stable and rapid development of the Chinese economy.国家社会科学基金项目“我国能源转型与发展战略问题研究”(18BJY069
EGFR-targeted CAR-T cells are potent and specific in suppressing triple-negative breast cancer both in vitro and in vivo
百年校庆之际,药学院刘文教授团队连续在Clinical & Translational Immunology和Cancer Immunology Research杂志上发表论文报道了一种靶向表皮生长因子受体(Epidermal growth factor receptor,EGFR)的新型嵌合抗原受体T细胞(CAR-T细胞)在小鼠肿瘤模型中能有效地抑制三阴性乳腺癌(Triple-negative breast cancer,TNBC),其与表观遗传调控因子CDK7抑制剂联合使用甚至达到治愈效果。三阴性乳腺癌侵袭性强、复发快、预后差,临床上缺乏有效的治疗手段。包括CAR-T治疗在内的免疫治疗已经成为癌症治疗中极具前景的治疗方式之一。研究团队构建了一种靶向EGFR的新型CAR-T细胞,证实了联合CAR-T肿瘤免疫治疗和表观遗传抑制剂能更有效抑制癌症的发生发展和缓解肿瘤免疫治疗引起的耐受,为临床上治疗三阴性乳腺癌提供了一种潜在的方式。
药学院刘文教授为文章的通讯作者,课题组助理教授夏琳、博士生郑早早、硕士生陈宇洁和公共卫生学院博士生刘珺懿为共同第一作者。【Abstract】Objectives: Triple-negative breast cancer (TNBC) is well known for its strong invasiveness, rapid recurrence and poor prognosis. Immunotherapy, including chimeric antigen receptor-modified T (CAR-T) cells, has emerged as a promising tool to treat TNBC. The identification of a specific target tumor antigen and the design of an effective CAR are among the many challenges of CAR-T therapy.
Methods: We reported that epidermal growth factor receptor (EGFR) is highly expressed in TNBC and consequently
designed an optimal third generation of CAR targeting EGFR. The efficacy of primary T lymphocytes infected with EGFR CAR lentivirus (EGFR CAR-T) against TNBC was evaluated both in vitro and in vivo. The signalling pathways activated in tumor and EGFR CAR-T cells were revealed by RNA sequencing analysis.
Results: Third-generation EGFR CAR-T cells exerted potent and specific suppression of TNBC cell growth in vitro, whereas limited cytotoxicity was observed towards normal breast epithelial cells or oestrogen
receptor-positive breast cancer cells. This capability was further demonstrated in vivo in a xenograft mouse model, with minimal offtumor cytotoxicity. Mechanistically, in vitro stimulation with TNBC cells induced the expansion of na€ıve-associated EGFR CAR-T cells and enhanced their persistence. Furthermore, EGFR CAR-T cells activated the interferon c, granzyme–perforin–PARP and Fas–FADD–caspase signalling pathways in TNBC cells.
Conclusion: We demonstrate that EGFR is a relevant immunotherapeutic target in TNBC, and EGFR CAR-T exhibits potent and specific antitumor activity against TNBC,suggesting the potential of this third-generation EGFR CAR-T as an immunotherapy tool to treat TNBC in the clinic.The work of LX was supported by the National Natural Science Foundation of China (31600748) and Project of XMU Training Program of Innovation and Entrepreneurship for Undergraduates (2019X0959), and the work of Wen Liu was supported by the National Natural Science Foundation of China (81761128015, 81861130370, 31871319 and 91953114), Fujian Province Health Education Joint Research Project (WKJ2016-2-09), Xiamen Science and Technology Project (2017S0091), Xiamen Science and Technology major projects (3502Z20171001-20170302) and Fundamental Research Funds for the Central University (20720190145).
该研究工作也得到了公共卫生学院的夏宁邵教授和罗文新教授的大力支持。该研究工作获得了科技部重点研发计划、国家自然科学基金项目、福建省自然科学基金项目、厦门市科技计划项目、厦门市科技重大专项、中央高校基本科研业务费专项资金等多个项目的经费支持
Single-pass transformation of syngas into ethanol with high selectivity by triple tandem catalysis
乙醇既可作为替代燃料或优质汽油添加剂亦是重要基础化学品,同时也是一种理想的氢载体。乙醇需求量近年增长迅速,我国需求缺口巨大,当前合成气合成乙醇有三种方法,其中直接法因在同一催化剂上存在多种反应通道,导致产物选择性不超过60%。另一方面,多步法路线虽然较为成熟,但因反应和分离/纯化步骤多,存在成本贵、能耗高等问题。发展合成气直接制乙醇的新方法和新路线具有重大意义。王野课题组在C1化学领域率先提出以接力催化控制反应选择性的新方法,并在合成气高选择性制备液体燃料、低碳烯烃和芳烃等方面取得成功。该工作是在王野教授、张庆红教授共同指导下完成的。醇醚酯化工清洁生产国家工程实验室高工康金灿、2018级博士生何顺和2017级博士生周伟为论文共同第一作者。陈明树教授课题组在原位红外、准原位XPS等表征中给予了支持,南京大学彭路明教授课题组在固体核磁表征方面提供了帮助。Synthesis of ethanol from non-petroleum carbon resources via syngas (a mixture of H2 and
CO) is an important but challenging research target. The current conversion of syngas to
ethanol suffers from low selectivity or multiple processes with high energy consumption.
Here, we report a high-selective conversion of syngas into ethanol by a triple tandem catalysis. An efficient trifunctional tandem system composed of potassium-modified ZnO–ZrO2,
modified zeolite mordenite and Pt–Sn/SiC working compatibly in syngas stream in one
reactor can afford ethanol with a selectivity of 90%. We demonstrate that the K+–ZnO–ZrO2
catalyses syngas conversion to methanol and the mordenite with eight-membered ring
channels functions for methanol carbonylation to acetic acid, which is then hydrogenated to
ethanol over the Pt–Sn/SiC catalyst. The present work offers an effective methodology
leading to high selective conversion by decoupling a single-catalyst-based complicated and
uncontrollable reaction into well-controlled multi-steps in tandem in one reactor.This work was supported by the National Key Research and Development Program of the Ministry of Science and Technology of China (No. 2017YFB0602201) and the National Natural Science Foundation of China (Nos. 91945301, 91545203, 21972116, 21433008, 21872112, 21673188 and 21690082). We acknowledge Prof. L. Peng and Y. Wen (Nanjing University, China) for performing NMR characterizations.该研究得到科技部重点研发计划(2017YFB0602201)和国家自然科学基金重大研究计划(91945301、91545203)等项目的资助
Lithium Storage Performance of High Capacity Material Si@CPZSin Lithium Ion Batteries
本文通过简单的溶胶-凝胶法以聚环三磷腈-4,4\'-磺酰基二苯酚聚合物(PZS)为碳源通过在硅纳米颗粒表面包覆碳层,成功构筑了核壳结构的Si@C复合材料. 通过对不同厚度碳层包覆的Si@CPZS的储锂性能进行研究,发现当硅表面PZS衍生碳厚度为10 nm时具有最佳的储锂性能,且经过长达290圈的循环后容量仍然保持在940 mAh·g-1,并且利用X射线衍射图谱、热重、比表面孔径测定仪及透射电镜等分析手段对样品进行了结构和组分分析. 本文进一步将Si@CPZS复合材料作为石墨的添加剂,结果表明30%的Si@CPZS复合材料可将石墨负极的容量提升至700 mAh·g-1.Carbon layers with different thicknesses were introduced into the surfaces of silicon (Si) nanoparticles by sol-gel method using poly (cyclotriphosphazene-co-4, 4\'-sulfonyldiphenol) as the carbon source. Technologies of X-ray diffraction, thermo-gravimetric analysis, Brunauer-Emmett-Teller and transmission electron microscopy were employed to analyze the structures and components of the as-prepared Si@CPZS composites. Electrochemical performance of Si@CPZS with different carbon thicknesses was studied. The results showed that Si@CPZS with carbon thickness of 10 nm possessed the best performance. Its capacity remained 940 mAh·g-1 after 290 cycles under 500 mA·g-1. As the addictive, the graphite-based anode contained 30% of Si@CPZS composite could achieve the specific capacity higher than 700 mAh·g-1.国家自然科学基金项目(No. 21573265,No.21805292)资助作者联系地址:1. 中国科学院兰州化学物理研究所,甘肃 兰州 730000;2. 中国科学院大学,北京 100080Author's Address: 1. Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China; 2. University of Chinese Academy of Sciences, Beijing 100080, China通讯作者E-mail:[email protected]
From Rural Industry to Horticulture Reform: Fei Xiaotong's Exploration of Rural Revitalization Paths
张亚辉,厦门大学人类学与民族学系教授、博士生导师;庄柳,厦门大学人类学与民族学系博士研究生。【中文摘要】20世纪初,基于对当时中国所处现代世界体系发展序列定位的不同认知以及由此而选取的不同比较研究对象,费孝通与理査德•H.托尼为中国的乡村振兴设计了两条不同的发展路径,前者主张以乡土工业为基点来构筑乡村的现代性,后者则强调园艺改革对乡村振兴的重要意义。在经历了系列思想转变后,晚年的费孝通也重新回归到对园艺改革的关注,希望在中国走一条乡土工业与园艺改革并举的乡村振兴道路。但无论如何,对共同体伦理的维护是乡村振兴的前提与关键。因而,重启费孝通和托尼关于中国现代化思想的比较研究,梳理费孝通关于乡村振兴路径的探索过程,不仅对理解中国社会科学的思想史具有理论价值,还对理解中国的乡村振兴策略具有重要的现实意义。
【Abstract】 In the early 20th century,based on the different cognitions of the sequence of the development of China in the modern world system and the different selected comparative research objects, Fei Xiaotong and Richard H. Tony designed two different development paths for the rural revitalization of China. The former advocated the construction of rural modernity based on rural industry,while the latter emphasized the importance of horticultural reform for rural revitalization. With a series of changes in his thoughts,in his later years,Fei Xiaotong returned to his focus on horticultural reform in the hope that China would embark on a rural revitalization path that combined rural industry with horticultural reform. However, the maintenance of community ethics was the premise and key to rural revitalization.Therefore,restarting the comparative study of Fei Xiaotong's and Tony's thoughts on China's modernization and sorting out Fei Xiaotong's exploration of the path of rural revitalization have not only theoretical value for understanding the history of the thought of Chinese social sciences,but also practical significance for understanding China's rural revitalization strategies.中央高校基本科研业务费专项资金资助项目“部落组织与封建王权:藏边地区的土地、政治与宗教的人类学研究”(20720171049
On the Training Model for International Chinese Talent under the “Belt and Road Initiative”
郑通涛,厦门大学海外教育学院教授、博士生导师,语言学博士;郭旭,厦门大学海外教育学院博士研究生。【中文摘要】“一带一路”建设的不断推进产生了大量的人才缺口,人才的匮乏对中国高等教育提出了新的挑战。以人才需求类型、地域分布、素质特征为出发点,基于“一带一路”建设需要提出的国际汉语人才培养模式包含如下六个要素:1.培养理念。人才培养需要树立“全球观”理念和“全人类”的格局感,契合建设人类命运共同体愿景。2.培养目标。人才培养的直接目标是为“一带一 路”建设提供人才支撑。3.培养主体。新形势下人才培养的主体不再仅是高校,而是转变成中外政府、高校、智库、企业和社会组织等组成的联合体。4.培养内容。建立在现状调査之上的培养内容,以提升学生的汉语交际能力为主,同时融合“一带一路”所需的专业知识,落实“汉语+ ”的政策方针。5.培养方式。“一带一路”沿线国家不同国情要求人才培养要以国别化的方式进行。6. 培养评价。在满足国际人才培养五个标准的前提下,人才培养评价体系由多方参与建设而成,从而保障人才培养质量。培养模式还需借助大数据挖掘、数据库建设、AI技术等手段,提高人才培养效率。以需求为导向构建的国际汉语人才培养模式,为“一带一路”教育共同体的建设工作提供学理支撑和应用借鉴。
【Abstract】The steady advancement of the “Belt and Road”,has created a large shortfall of talent,presenting challenges to China's higher education. With type of talent demand,geographical distribution and quality characteristics as the starting points,and based on the “Belt and Road”,construction,the training model for international Chinese talent comprises six elements.First,the training concept:talent training needs to establish a “global outlook” concept and a sense of “all humanity” to suit the vision of building a community of shared destiny for mankind. Second,the training goal: The immediate goal of talent training is to provide talent support for the construction of the “Belt and Road”. Third,the training subject : Universities are no longer the only entities for talent training in the new situation,and the main entities are to be transformed into a consortium of Chinese and foreign governments,universities,think tanks,enterprises and social organizations. Fourth,the training content : Talent training should be based on the findings of surveys and focused on improving students’ Chinese communicative competence; moreover,it should be combined with the professional knowledge required by the “Belt and Road” and implement the “Chinese + ” policy and guidelines. Fifth,the training method: The different national conditions of the countries along the “Belt and Road”require talent training to be carried out in a country-specific manner. Last,the evaluation system: On the premise of meeting the five international talent training standards,the talent training evaluation system should be built by all parties concerned so as to ensure the training of talents. In addition to the six elements,the model also needs to utilize big data mining,database construction and AI technology to improve the efficiency of personnel training. The demand - oriented training model for international Chinese talent provides academic sup¬port and practical references for the construction of the “Belt and Road” education community
Labor Misallocation and Total Factor Productivity
邓明,厦门大学经济学院教授、博士生导师,经济学博士;柳玉贵,招商证券工作人员;王劲波,厦门大学经济学院助理教授,经济学博士。【中文摘要】要素配置扭曲被认为是抑制中国全要素生产率增长的重要因素之一,但其中背后的机制还缺乏足够深入的研究。包含农业部门与非农业部门的两部门模型可就劳动力配置对全要素生产率的抑制作用及其作用机制进行研究。模型的分析结构表明,劳动力在农业部门和非农业部门间的配置扭曲会抑希(劳动力从农业部门向非农业部门流动,并阻碍经济从农业向非农业的转型,同时通过这一作用机制也抑制了全要素生产率增长。为了检验这一机制,基于1985—2015年的中国省际面板数据,使用中介效应检验方法进行了实证研究。实证研究结果表明,农业部门与非农业部门间的劳动力配置扭曲确实抑制了经济由农业向非农业转型,并通过这一中介抑制了全要素生产率增长,在考虑了变量的度量方式和解释变量的内生性之后,该研究结论依然是成立。
【Abstract】 Factor misallocation is considered one of the most critical elements that restrain the growth of total factor productivity in China,but the mechanism behind this relation has not been studied in depth. This paper constructs a two-lsector model involving the agricultural sector and the non- lagricultural sector to study the restraining effect of labor misallocation on total factor productivity and related mechanisms. The theoretical study reveals that labor misallocation between the agricultural sector and the non -lagricultural sector will delay labor transfer from the former to the latter,by which labor misallocation will restrain the growth of total factor productivity. In order to test the above mechanism,this paper takes an empirical study by use of China's provincial panel data from 1985 to 2015 and the mediating effect model. The empirical study shows that labor misallocation between the agricultural sector and the non-lagricultural sector does restrain the economy ,s transformation from agriculture to non - lagriculture, and that this effect is the mediating mechanism acting on the effect of labor misallocation on the growth of total factor productivity. This outcome remains robust even we change the measurement of total factor productivity growth and consider the endogeneity of labor misallocation.国家自然科学基金面上项目“中间产品进口、技能偏向性技术进步与技能溢价”(7197311);福建省社会科学规划项目“中国企业劳动生产率差异的技术选择效应与技术吸收效应研究”(FJ2019B136