94 research outputs found
De principiis eloquentiae e sententia Platonis [microform] /
No full textFilmed with: Küppers, J. J. / Curae criticae in Thucydidem -- Niggemeyer, T. / De Alcmane poeta Laconico -- Lohmann, W. / Quaestionum Lucretianarum capita duo -- Kroon, T. T. / Specimen litterarium exhibens Quaestiones Catullianas -- Cobet, C. G. / Oratio de arte interpretandi grammatices et critices fundamentis innixa primario philologi officio -- Panofsky, H. / Quaestionum de historiae Herodoteae fontibus pars prima -- Hoffmans, W. A. / Theses controversae quas...in scholia Horatiana quaestiones selectae... -- Hoffs, F. van / De rerum historicarum in Aeschyli Persis tractatione poetica -- Horkel, J. / Analecta Horatiana -- Hoelscher, L. / De vita et scriptis Lysiae oratoris -- Hartmann, G. F. / Observationes in Plutarchi Vitam Timoleontis -- Hildenbrand, F. J. / Sex. Properti elegiarum librum primum commentariis grammaticis -- Hilff, F. / Observationes criticae et exegeticae ad Silii Italici Punicorum... -- Vahlen, J. / Quaestiones Ennianae criticae -- Spiro, F. / [Epithalamion] Wolfgang Passow und Helene Passow... -- Westerwick, K. / De Republica Platonis -- Wollseiffen, M. / De syllabarum in brevem vocalem desinentium apud Homerum productione -- Wolf, F. H. E. / Observationes ad scholia in Platonem -- Nauta, B. A. / Senecae librum De providentia (1825) -- Neissner, E. / Kampf des Horaz für eine bessere Geschmacksrichtung in der römischen Poesie -- Seneca / L. Annaei Senecae liber De providentia.Diss.Includes bibliographical references.Microfilm.Mode of access: Internet
Policing Standard Form Contracts in Germany and South Africa: A Comparison
No full textThe aim of this dissertation is to compare South African law on standard form contracts against the corresponding German law. Thus, the responses of both legal systems to the special situation occurring in cases of standard form contracts will be compared and evaluated. Thereby, the focus of this dissertation is to determine whether South African law on standard form contracts provides adequate protection for the submitting party. German law on standard form contracts provides the basis and outline against which South African law will be critically evaluated. German law was selected for this task, as it was one of the first legal systems, which enacted legislation, and addresses the issue systematically. It should be noted that this dissertation does not aim to evaluate German law on standard form contracts. In the first part of this dissertation I will provide a brief definition of the notion of freedom of contract and consumer protection. I will then proceed to highlight the relevance of standard form contracts in modern society and outline the problems associated with such contracts. This will be followed by a discussion of whether standard form contracts can be considered as classical contracts. In the second part of this dissertation I will outline the law on standard form contracts in both jurisdictions. Concerning the German law, I will give a brief overview of what the relevant provisions state. Concerning South African law, I will briefly illustrate what the relevant common law appears to be without going into far too much depth. Such outlines of the applicable laws are necessary in order to acquaint the reader with some of the important themes that this dissertation will discuss in detail. In part three the actual comparison and evaluation will follow. The comparison will include a detailed illustration of the law on standard form contracts in both jurisdictions. Thereby, some repetition in regard to the applicable law cannot be avoided. Thereafter, the evaluation will more specifically investigate whether South African law is effective in achieving its aims and whether South Africa should introduce legislation on standard form contract terms
Activation of sea urchin sperm motility is accompanied by an increase in the creatine kinase exchange flux
Get PDFThe kinetics of the creatine kinase (CK) reaction were studied in suspensions of quiescent and active, intact sea-urchin spermatozoa in artificial seawater, using 31P-NMR magnetization transfer. In inactive sperm, no CK-mediated exchange flux was detected, whereas in activated motile sperm, the forward pseudo-first-order rate constant was 0.13±0.04 s-1 at 10 °C, corresponding to a steady-state CK flux of 3.1±0.5 mM·s-1. Intracellular pH shifted from 6.6±0.1 to 7.6±0.1 upon activation. The phosphocreatine (PCr)/ATP and PCr/Pi ratios were only marginally reduced in activated sperm, whereas the estimated cytosolic free ADP concentration increased remarkably from 9 µM in quiescent, to 114 µM in activated spermatozoa. The elevation of CK flux upon sperm activation is discussed in the light of the proposition that in sea-urchin spermatozoa, which are fuelled entirely by oxidative phosphorylation, high-energy phosphate transport is mediated by a 'CK/PCr shuttle'
Dynamic changes of ADC, perfusion, and NMR relaxation parameters in transient focal ischemia of rat brain
No full textThe potential of multiparametric MRI parameters for differentiating between reversibly and irreversibly damaged brain tissue was investigated in an experimental model of focal brain ischemia in the rat. The middle cerebral artery (MCA) was occluded by intraluminal suture insertion for 60 or 90 min, followed by 4.5 h of reperfusion. The apparent diffusion coefficient (ADC) of brain water, T-1 and T-2 relaxation times, and CBFi, an MR-derived index of cerebral perfusion, were repeatedly measured and correlated with the outcome from the ischemic impact. A novel user-independent approach for segmentation of ADC maps into classes of increasing injury was introduced to define regions of interest (ROIs) in which these parameters were evaluated. MCA occlusion led to a graded decline of ADC, which corresponded with both the severity of flow reduction and an increase in T-1 and T-2 relaxation times. Removal of the suture led to a triphasic restitution of blood flow consisting of a fast initial rise, a secondary decline, and final normalization. Postischemic reperfusion led to a rise of ADC irrespective of the duration of ischemia. However, the quality of recovery declined with increasing severity of the ischemic impact. Throughout the observation time, T-1 and T-2 showed a continuous increase, the intensity of which correlated with the severity of ADC decline during ischemia. Particularly with longer ischemia time, elevated T-2 in combination with reduced ADC yielded a lower probability of recovery during recirculation, while intraischemic perfusion information contributed less to the prediction of outcome. In conclusion, the combination of MR parameters at the end of ischemia correlated with the probability of tissue recovery but did not permit reliable differentiation between reversibly and irreversibly damaged tissue
In situ measurements of creatine kinase flux by NMR. The lessons from bioengineered mice
No full textP-31 nuclear magnetic resonance (NMR) is uniquely suited to measure the kinetics of the phosphoryl-exchange reaction catalyzed by creatine kinase in intact mammalian tissue, especially striated muscle. Recently developed transgenic mouse models of the creatine kinase iso-enzyme system open novel opportunities to assess the functional importance of the individual iso-enzymes and their relative contribution to the total in situ flux through the CK reaction. This chapter reviews the most recent findings from NMR flux measurements on such genetic models of CK function. Findings in intact mouse skeletal and cardiac muscle in vivo are compared to data from purified mitochondrial and cytosolic creatine kinase in vitro. The relevance of findings in transgenic animals for the function of CK in wild-type tissue is described and the perspectives of transgenic techniques in future quantitative studies on the creatine kinase iso-enzyme system are indicated
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