1,723,622 research outputs found
Dataset for QSAR Modeling of DPP-4 Inhibitors
No full textThe data that used for DPP-4 inhibitors QSAR modeling with machine learning methods were raw data from ChEMBL, initial processing data, and data partitioning for modeling which is divided into 3 parts i.e. training data, validation data (internal validation) and data test (external validation). This dataset also contained an explanation of the methods and tools used for modeling, and the predicted results of pIC50 values from the best model (from external validation data)
Dataset for QSAR Modeling of DPP-4 Inhibitors
No full textThe data that used for DPP-4 inhibitors QSAR modeling with machine learning methods were raw data from ChEMBL, initial processing data, and data partitioning for modeling which is divided into 3 parts i.e. training data, validation data (internal validation) and data test (external validation). This dataset also contained an explanation of the methods and tools used for modeling, and the predicted results of pIC50 values from the best model (from external validation data)
Fotografi Fashion Brand Nohari Karya Desainer Hermansyah Afthony
Full text linkFotografer mengambil fotografi fashion karena merupakan fotografi yang mempunyai tantangan tersendiri untuk bisa memotret dengan model. Fotografi fashion juga sudah dilakukan dari awal perkuliahan hal tersebutlah yang membuat penciptaan ini mengambil fotografi fashion. Pada penciptaan fotografi fashion brand Nohari karya desainer Hermansyah Afthony yang membuat foto di luar ruangan. Pemilihan brand Nohari merupakan adanya kedekatan dengan sudah melakukan kolaborasi dan busana dari Hermansyah Afthony mempunyai kekhasan tersendiri terutama di bidang kontemporer etnik dari setiap busananya. Rumusan masalah pada penciptaan ini adalah bagaimana memvisualisasikan fotografi fashion terhadap busana brand Nohari dan bagaimana membuat karya fotografi fashion dengan ide penciptaan pergaan busana di luar ruangan. Menggunakan metode eksplorasi, eksperimentasi, dan perwujudan membuat penciptaan ini mempunyai fotografi fashion yang berbeda dengan karya foto fashion sebelumnya. Fotografi fashion penciptaan ini mewujudkan peragaan busana dalam wujud patung yang berada di berbagai lokasi di Yogyakarta. Hasil akhir penciptaan ini bisa memvisualisasikan bentuk baru dari fotografi fashion brand Nohari dan mewujudkan fotografi fashion dengan ide penciptaan peragaan busana di luar ruangan. Melalui penciptaan karya fotografi fashion ini diharapkan bisa menjadi daya tarik ke kalangan masyarakat yang lebih luas serta mempunyai nilai jual yang tinggi. Fotografi fashion ini juga diharapkan bisa menjadi salah satu penciptaan yang baru dalam dunia fotografi fashion.
Kata kunci : fotografi fashion, Nohari, Hermansyah Afthony, media promos
Study of Mangan Peroxidase (Mnp) Enzymes from Pleurotus Ostreatus Produced using Coffee Grounds and Rice Bran as Substrates through Response Surface Methodology
Full text linkThis study aimed to optimize the production of Manganese Peroxidase (MnP) enzyme from Pleurotus ostreatus using agricultural waste substrates such as coffee grounds (CG) and rice bran (RB) through Response Surface Methodology (RSM) approach. Optimization was conducted using a Central Composite Design (CCD) with three main variables, namely MnSO₄ concentration (0.5-1.5) mM, incubation temperature (25-35) °C, and reaction time (20-30) min. The enzyme fractionation process was carried out by ammonium sulfate saturation (0-20%), (20-40%), (40-60%), followed by dialysis, and SDS-PAGE analysis. The results showed that the 0-20% fraction of CG:RB (50:50) substrate had the highest enzyme activity, which was 20.588 ± 0.141 U/mL, with the highest specific activity of 76.967 ± 0.325 U/mg. The highest protein content was found in CG:RB (0:100) substrate at 0.825 ± 0.016 mg/mL. However, the enzyme activity was lower due to the presence of non-enzymatic proteins and natural inhibitors. This study successfully demonstrated that the substrate combination of CG:RB (50:50) provided optimal results for MnP production. The Response Surface Methodology proved effective in optimizing process variables, providing great potential for biotechnology applications using agricultural waste as an environmentally friendly raw material.Keywords: Pleurotus ostreatus, Manganese Peroxidase, Coffee Dregs, Rice Bran, RSM, SDS-PAG
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