1,773,398 research outputs found

    Osteoindctivization of dental implants and bone- defect-filling materials

    No full text
    http://www.woodheadpublishing.com/en/book.aspx?bookID=159

    CMAS corrosion of EB PVD TBCs: Identifying the minimum level to initiate damage

    Get PDF
    Over the last decade a significant amount of research has been conducted into the durability of thermal barrier coatings (TBCs) focusing mainly on issues of oxidation, erosion and foreign object damage (FOD). However, as the performance and durability of TBCs has improved the temperatures at which they operate has increased. This increase in temperature has resulted in another lifing issue for EB PVD TBCs, namely that of CMAS attack. Calciumâ  magnesiumâ  alumino-silicate (CMAS) attack occurs when atmospheric dust that has deposited on the surface of turbine blades melts and wicks into the columns of the TBC. This occurs at temperatures above 1240â  1260 à °C and results in the degradation of the columnar microstructure of the TBCs. Due to the fact that TBCs operate in a temperature gradient CMAS only infiltrates part of the coating before solidifying. There are a number of issues associated with CMAS attack, both chemical and mechanical. From a chemical point of view CMAS attack of electron beam (EB) physical vapour deposited (PVD) TBCs can be considered as a form of corrosion; when there is a lot of excess CMAS on the surface of a coated component Yttria diffuses out of the TBC into the molten CMAS resulting in a tâ ² to monoclinic phase transformation in the yttria stabilised zirconia (YSZ), CMAS attack also results in localised melting and subsequent re-precipitation of the coating resulting in a loss of the defined columnar microstructure. While from a mechanical point of view the CMAS, once re-solidified, reduces the strain compliance of the EB PVD and can result in spallation of the TBC on cooling. Furthermore, current studies have indicated that small amount of CMAS infiltration significantly increases the erosion rate of EB PVD TBCs. This paper covers various aspects of CMAS attack of EB PVD TBCs, specifically looking at minimum levels of CMAS required to initiate damage, as well as investigating it from an erosionâ  corrosion

    EB-NPCs are significantly different than our previously differentiated NPCs.

    No full text
    EB-NPCs cluster away from both pluripotent stem cells and NPCs derived from both ESCs and iPSCs by our previously published method in both (A) Principal component analysis and (B) hierarchical clustering. (C) EB-NPCs show a lack of TGFβ2 transcript as shown by whole genome expression analysis.</p

    EB-derived erythrocytes are uniformly of the primitive lineage.

    No full text
    A) Single-cell RT-PCR (Biomark System, Fluidigm) from FACS-sorted primary and EB-derived erythroid cells as indicated in the colour coded groups for embryonic (Hba-x and Hbb-y) and adult (Hba-a1/2 and Hbb-b1/2) globin genes. B) PCA of expression data from a panel of 40 probes used for single-cell RT-PCR (Biomark System, Fluidigm) to distinguish primitive and definitive lineages of specific differentiation stages. EB-derived erythroid cells (dark and light blue dots) most closely resemble E9.5 primary cells (orange circles with a black outline) as indicated with the black dotted circle.</p

    A Német Fürjész eb alkalmazhatósága hazánkban

    No full text
    A Német Fürjész eb mint hazánkban ritkának számító kutya fajta jellemzése, fajtaleírása, standardje. A különböző vadászterületeken történő alkalmazása, eredményessége. A különböző minősítések, vizsgakövetelmények leírásai. A fajta ajánlás mindazoknak akik szeretik a vadászatot, illetve vadászathoz egy kutyát szeretnének használni, valamint meglátják az értéket a kutyában. Összehasonlítás más német vadászkutyákkal.vadgazda mérnökBSc/B

    Supplementary Figure 7 from <sup>177</sup>Lu-DOTA-EB-TATE, a Radiolabeled Analogue of Somatostatin Receptor Type 2, for the Imaging and Treatment of Thyroid Cancer

    No full text
    Supplemental Figure 7: VAC treatment did not improve therapeutic efficacy of DOTA-EB-TATE in either low- or high-SSTR2 expressing tumors. (A) No effect of VAC on the tumor progression in the 177Lu-DOTA-EB-TATE treated FTC133 (low-SSTR2-expressing) subcutaneous xenograft mice model. C-control mice that received 177Lu-DOTA-EB-TATE (n=8); VAC-valproic acid treated mice that received 177Lu-DOTA-EB-TATE (n=9). Data are presented as mean{plus minus}SEM. (B) No effect of VAC on the tumor progression in the 177Lu-DOTA-EB-TATE treated AR42J (high-SSTR2-expressing) subcutaneous xenograft mice model. C-control mice that received 177Lu-DOTA-EB-TATE (n=8); VAC-valproic acid treated mice that received 177Lu-DOTA-EB-TATE (n=7). Data are presented as mean{plus minus}SEM.</p

    The processing windows for NiTi alloy manufactured by PBF-EBessing windows for NiTi alloy manufactured by PBF-EB

    No full text
    Nickel titanium (NiTi) as one of the most utilized shape memory alloy has drawn significant interest due to its unique characteristics. However, NiTi is also considered a susceptible material to smoke during electron beam powder bed fusion (PBF-EB) process, which restricts the manufacturing possibility of the components. This work investigates processing windows for pre-heating and melting of NiTi powder to allow fabricating healthy parts. The smoke tests were carried out at different focus offsets and beam currents in relation to beam speeds. It is noted that a smaller EB spot can effectively prevents smoking while it may cause the strong powder bonding which can affect powder recycling negatively. Thus, a less focused beam (or larger EB spot) was selected to reach medium but efficient sintering. Moreover, it was observed that a negative defocused EB mitigates the smoke phenomenon compared to the positive defocused EB with a similar spot size. After that, parts having a relative density over 99% were successfully manufactured with PBF-EB. It is also found that with the same level of energy input, a set of low power with low scan speed leads to denser parts compared to a set of high power with high scan speed. This is attributed to less complexities in the melt dynamic which is related to lower density of impacting electrons. Besides, the combination of low power with low scan speed also improves geometrical accuracy of the parts attributed to the smaller spot size and smaller melt pool sizes. </p

    Development of EB-PVD TBC'S : the role of deposition temperature and plasma assistance

    No full text
    Gas turbine manufacturers have achieved continuingly improved engine efficiency and thrust-to-weight ratio by designing with increased Turbine Entry Temperature (TET). The protection of High Pressure Turbine (HPT) aerofoils with thin insulating ceramic coatings, referred to as Thermal Barrier Coatings (TBC's), has emerged as the next key technology to allow for further increases in TET. Electron Beam Physical Vapour Deposition (EB-PVD) is today's most promising processing route for the manufacture of TBC's applied on aerofoils. The purpose of this work was to generate a sound understanding of the relationship between the EB-PVD process and the structure of Zr02- 8wt%Y2O3 ceramic deposits, which could be exploited to achieve improved TBC performance. In particular, the role of deposition temperature and the potential benefits in using RF and DC plasma assistance of the EB-PVD process were investigated, together with their influence on the erosion performance of EB-PVD TBC's. The significance of particulate erosion as a degradation mode is assessed under conditions representative of the HPT environment. New explorable routes to achieve reduced thermal conductivity of EB-PVD TBC's are identified. It is shown that EB-PVD TBC's deposited at low temperature contain a massive content of microscopic voidage (-50%) which is responsible for their lack of thermal stability. The growth of EB-PVD TBC's at elevated deposition temperatures is explained in terms of dynamic sintering, whereby diffusion processes compete against the high rate arrival of vapour atoms to overcome the spontaneous defectiveness of the atomic build up. Modelling of the gas discharge physics has highlighted scope for improving the effectiveness of plasma assistance in causing ceramic structural damage, capable of modifying the coating thermal properties. The erosion rate of EB-PVD TBC's is shown to be controlled by their degree of plastic deformation upon particle impacts, which in turn depends on the ceramic column diameter and inherent porosity
    corecore