1,810 research outputs found
Além da enxada, a utopia: a colonização italiana no oeste catarinense
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas. Programa de Pós-Graduação em História.Através da teoria e metodologia da História Oral, busca perceber a experiência migratória dos italianos e seus descendentes que migraram da Região Colonial Italiana, no Rio Grande do Sul, para o Oeste de Santa Catarina, a partir das primeiras décadas do séc. XX. Apresenta vários aspectos do cotidiano dos migrantes na nova terra, como o trabalho, o lazer e a família. Analisa quais as representações do passado são transmitidas pelas pessoas que vivenciaram a referida experiência migratória
Construyendo la ópera nacional: A Marília de Itamaracá de L. V. De-Simoni
No full textLuiz Vicente De Simoni (1782-1881) was an Italian physician who went to Rio de Janeiro in 1817, and was constantly involved in the musical and theatrical scene of the city. He is the author of Marília de Itamaracá (1854, music by Adolpho Maersch), considered by some authors as the first “Brazilian” opera. The subject is historical and narrates some episodes of the 17th century war against the Dutch. One of his main concerns was the use of Brazilian and Portuguese themes in operas, in order to invent something “national”. As part of a broader movement, the idea was to explore Brazilian people, landscape and traditions as the main subject for operas that should be sung in Portuguese. The movement was related to a broader political project sponsored by the government and the Emperor, aimed at the revision of Brazilian history and the construction of a new cultural identity for the country. The purpose of this paper is to examine some aspects of the libretto of Marília de Itamaracá and the ideas discussed in its preface, showing the contradictions and tensions involved in the creation of a “national” identity through operas
Inhibition of mannose binding lectin is protective in experimental traumatic brain injury
No full textAIMS
We have previously demonstrated the presence of mannose binding lectin (MBL) in the brain of traumatic brain injured (TBI) patients and in that of mice subjected to experimental TBI, where MBL-C exceeds MBL-A. We have also shown that the susceptibility to TBI is significantly reduced in MBL double knock-out compared to wild type mice at 2-5 weeks postinjury (1). We have now evaluated the effect of the administration of two multivalent glycomimetic MBL-ligands, Polyman-2 (2) and Polyman-9, on mouse TBI progression.
METHODS and RESULTS
Polyman-2 and Polyman-9 were selected for their interaction with MBL-A and MBL-C, evaluated by surface plasmon resonance (SPR). Polyman-2 showed higher binding to MBL-A, while Polyman-9 showed a similar binding to MBL-A and MBL-C. Furthermore, Polyman-9 binding to MBL-C was higher than that of Polyman-2.
Male C57Bl/6 mice were subjected to sham or controlled cortical impact brain injury (parameters: velocity 5 meter/sec and depth 1 mm). At 10 minutes postinjury, mice randomly received an intravenous infusion of either Polyman-2, Polyman-9 or saline. Functional outcome was evaluated using the neuroscore and beam walk tests weekly, up to 4 weeks postinjury. Brain-injured mice receiving saline or Polyman-2 had similar neurobehavioral deficits. On the contrary, brain-injured mice receiving Polyman-9 had significantly reduced sensorimotor deficits compared to saline treated mice at 2-4 weeks postinjury.
CONCLUSIONS
Differently from Polyman-2, Polyman-9 confers neurobehavioural protection after TBI. This effect may be due to Polyman-9 higher affinity to MBL-C. Together with the decreased response to TBI reported in MBL KO mice, these data demonstrate the MBL relevance in TBI setting.
1) Longhi L, Orsini F, De Blasio D, Fumagalli S, Ortolano F, Locatelli M, Stocchetti N, De Simoni M G, Mannose binding lectin expressed after clinical and experimental traumatic brain injury and its deletion is protective. Critical Care Medicine 2014, in press
2) Orsini F, Villa P, Parrella S, Zangari R, Zanier E, Gesuete R, Stravalaci M, Ottria R, Reina JJ, Paladini A, Micotti E,Ribeiro-Viana R, Rojo J, Pavlov VI, Stahl GL, Bernardi A, Gobbi M, and
De Simoni MG. Targeting mannose binding lectin confers long lasting protection with a surprisingly wide therapeutic window in cerebral ischemia. Circulation 2012; 126: 1484-1494
Sunius simoni
No full textSunius simoni (QUEDENFELDT, 1881) Material examined: Spain: Andalucía: 1 ex., Cádiz, East Facinas, Embalse de Almodóvar, 36°09'N, 5°38'W, 110 m, under stones, 3.I.2017, leg. Forcke (MNB). Comment: Sunius simoni is endemic to the extreme south of Spain and North Morocco. Its distribution is mapped in ASSING (2008).Published as part of Assing, Volker, 2017, A revision of Sunius XVI. Two new species from Iran and Iraq (Coleoptera: Staphylinidae: Paederinae), pp. 247-254 in Beiträge Zur Entomologie = Contributions to Entomology (Beitr. Entomol.) (Beitr. Entomol.) 67 (2) on page 248, DOI: 10.21248/contrib.entomol.67.2.247-253, http://zenodo.org/record/475491
Pseudosinella simoni Jordana & Baquero 2007
No full textPseudosinella simoni Jordana & Baquero, 2007 Pseudosinella simoni Jordana & Baquero, 2007: 13. MATERIAL EXAMINED. — Spain • 23 specimens on slide and 100 (approximately) in ethyl alcohol; SSD-9, slide 07; Sierra de Guadarrama, Segovia; Ortuño et al. leg.; MZNA • 2 specimens; SSD-11, slide 17; same data; MZNA • 1 specimen on slide and 11 in ethyl alcohol; SSD-24, slide 03; same data; MZNA. REMARKS Known only to date from the specimens of the type locality (Navacerrada, Sierra de Guadarrama, Spain) (Jordana & Baquero 2007). It therefore appears for the second time in the same area.Published as part of Baquero, Enrique, Jordana, Rafael & Ortuño, Vicente M., 2021, Distinctive Collembola Communities in the Mesovoid Shallow Substratum: Entomobryomorpha of the Sierra de Guadarrama National Park (Central Spain), pp. 37-78 in Zoosystema 43 (3) on page 75, DOI: 10.5252/zoosystema2021v43a3, http://zenodo.org/record/448716
Hydrologic response in the initiation area of the Dimai debris flow (Dolomites, Italian Alps)
No full textDebris flows are fast moving landslides of mixed water and poorly sorted debris (IVERSON, 1997; CRUDEN AND VARNES, 1996). Because of the high flow velocity, impact forces, and long runout, debris flows are commonly regarded as one of the most hazardous landslide types (JAKOB, 2005). The Dolomites region (NE Italian Alps) has one of the most frequent return intervals for large debris flows on the world (PASUTO AND SOLDATI, 2004; SKERMER AND VANDINE, 2005).
In the Dolomites the landscape is dominated by steep dolomite massifs rising up to 3300 m a.s.l. The rocky cliffs are connected to the bottom of alpine valleys by means of milder slopes where bedrock is covered by a thick debris talus, deposited in post-glacial climatic conditions. Debris flow channels are deeply incised in the talus slope and feeded by small headwater basins located on the cliffs (MARCHI AND TECCA, 1992; BERTI et alii, 199). These basins are typically very steep (45°-60° on the average) and mostly consist of exposed bedrock with no vegetation and almost absent soil cover.
During high intensity short duration thunderstorms, rainfall water is collected by the rocky watersheds as overland flow and trunk streams incised in bedrock, and quickly delivered to the talus cones. Most of this water infiltrates into the channel bed debris and flows downstream as subsurface stormflow. However, when the infiltration capacity of the streambed is exceeded, surface flow appears in the channel and debris flows are triggered by the progressive erosion of the loose bed debris (BERTI AND SIMONI, 2005).
Although this initiation mechanism has been widely recognized in the field (e.g. CANNON et alii, 2003), monitoring data describing the onset of channel runoff and the triggering process are still lacking. In this paper we describe the monitoring systems installed on a typical debris flow catchment of the Dolomites (Dimai basin, Cortina d’Ampezzo, Belluno), with the main aim of describing the hydrologic response in the initiation area
M. J. Vermaseren avec la collaboration de Piero Simoni, Liber in Deum. L'apoteosi di un iniziato dionisiaco., 1976. EPRO, t. 53
No full textTurcan Robert. M. J. Vermaseren avec la collaboration de Piero Simoni, Liber in Deum. L'apoteosi di un iniziato dionisiaco., 1976. EPRO, t. 53. In: Revue des Études Anciennes. Tome 82, 1980, n°1-2. pp. 135-136
M. J. Vermaseren avec la collaboration de Piero Simoni, Liber in Deum. L'apoteosi di un iniziato dionisiaco., 1976. EPRO, t. 53
No full textTurcan Robert. M. J. Vermaseren avec la collaboration de Piero Simoni, Liber in Deum. L'apoteosi di un iniziato dionisiaco., 1976. EPRO, t. 53. In: Revue des Études Anciennes. Tome 82, 1980, n°1-2. pp. 135-136
Cytokine-neurotransmitter interactions in the brain
No full textThe data reviewed in this study show that immune-active molecules, such as infectious agents and their components, and cytokines, may induce profound alterations in several neurotransmitters in the CNS. The activation of the immune system elicits fever, behavioral and neuroendocrine changes and may be involved in neuropathological changes occurring in CNS conditions. These effects may be achieved through and accounted for by the changes induced in central neurotransmitters and in the neuroendocrine system by immune challenges. The present review will summarize the available evidence of the reciprocal interactions between cytokines and neurotransmitters in the CNS
The role of trust in the diffusion of privacy-invading digital technologies
No full textThis paper analyses the process of diffusion of a class of technologies that raises concerns regarding the public administration's access to sensitive data collected by it. We apply the methodology of agent-based modelling to simulate the process of diffusion of those technologies and, in extension to previous studies, consider both the rules for the diffusion of innovation and, simultaneously, those for the diffusion of political trust in a population. In this manner, we can explore the interplay between the agents' propensity towards innovation and the barriers that may derive from the lack of trust in the public administration and its management of the technology used to collect and store data belonging to citizens. The model and the study's findings are illustrated by referring to the case of smart cities, since these represent a set of technologies that are prone to misuse by the political authority. We conclude the paper by describing some scenarios that, according to the theoretical predictions of our model, should lead to the non-adoption of technology in populations that possess certain levels of trust and specific mechanics of diffusion at the time the diffusion begins
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