236 research outputs found
ANTAT-CU Real Time: Een gekwantificeerde beoordeling van de verbaal-mondelinge effectiviteit en efficiëntie middels de ANTAT
No full textDe Amsterdam-Nijmegen Test voor Alledaagse Taalvaardigheden (ANTAT) brengt bij personen met afasie (PMA) de verbaal-mondelinge communicatie in kaart. Echter is de scoring subjectief door het ontbreken van een interne standaard. Ruiter et al. (2011) hebben door gebruik van Content Units (CU) een kwantitatievere scoringswijze ontwikkeld voor het in kaart brengen van zowel de verbaal-mondelinge effectiviteit als de efficiëntie. Deze scoringswijze was zeer arbeidsintensief, doordat er orthografisch getranscribeerd moest worden. De huidige studie heeft een scoringsmethode ontwikkeld waarbij content units tijdens de afname al gescoord kunnen worden (ANTAT-CU Real Time). Uitingen van 31 gezonde participanten en 8 PMA zijn in deze studie met beide scoringsmethoden gescoord en vergeleken. Uit deze studie blijkt dat de ANTAT-CU Real Time een volwaardig alternatief is
Five-year Development of Psychopathology in Young People with Intellectual Disabilities
Full text linkKoot, J.M. [Promotor]Verhulst, F.C. [Promotor]Dekker, M.C. [Copromotor
Tussen de oren, voor paard en pony in praktijk
Full text linkDit boek is echter voor tussen de oren van de eigenaar, verzorger, ruiter of amazone. Het bevat praktische adviezen op het gebied van voeding, opfok, gezondheid, africhting, vruchtbaarheid, beweiding en bodem
Het effect van woordfrequentie in semantische taken van de DuLIP-Kids-testbatterij
No full textHet Dutch Linguistic Intraoperative Protocol, of DuLIP, is een testbatterij die gebruikt wordt bij wakkere-hersenoperaties om hersengebieden die betrokken zijn bij taalproductie en taalbegrip te lokaliseren. Omdat wakkere-hersenoperaties steeds vaker bij kinderen worden uitgevoerd, is een DuLIP-KIDS-taak ontwikkeld. Voor het ontwikkelen van een test zijn enkele factoren van belang, waaronder woordfrequentie. Van deze woordfrequentie wordt aangenomen dat deze invloed heeft op de snelheid waarop woorden uit het mentale lexicon worden opgehaald, maar er is discussie over welke informatie sneller wordt opgehaald bij woorden met een hogere woordfrequentie: De semantische informatie en/of de fonologische informatie.
Dit onderzoek onderzoekt het effect van de woordfrequenties van de doelwoorden van de items op de score van drie taken van de DuLIP-KIDS-testbatterij: De benoemtaak, de semantische odd-word-out-taak en de semantische odd-picture-out-taak, waarbij de semantische taken een groter beroep doen op het semantische systeem in het mentale lexicon. Daarnaast onderzoekt dit onderzoek de verschillen in scores tussen twee leeftijdsgroepen (10 tot 13 jaar en 16 tot 17 jaar) op deze testen
The development of quantitative methods for residues in foods of animal origin with validation according to commission decision 2002/657/EC
Full text linkResidue methods were developed for the determination o f the coccidiostat robenidine in egg, the benzimidazoles (13) in liver (albendazole 2-amino albendazole sulphone, albendazole sulphoxide, albendazole sulphone, thiabendazole, oxfendazole or fenbendazole sulphoxide, hydroxy mebendazole, amino flubendazole, fenbendazole sulphone, oxibendazole, mebendazole, flubendazole and albendazole) and the triphenylmethane dyes (4) in salmon (malachite green, crystal violet, leucomalachite green and leucocrystal violet). The methods were validated according to the criteria defined in Commission Decision 2002/657/EC. Robenidine was extracted from egg with acetonitrile and the sample extracts analysed by liquid chromatography (LC) with ultraviolet (UV) spectrophotometric detection at 317 nm. The decision limit (CCa) and the detection capability (CCP) were 10 |xg.kg_I and 17 ng.kg'1 respectively.
The benzimidazoles were extracted from liver samples with ethyl acetate, sample extracts were defatted with hexane and cleaned up by automated solid-phase extraction (SPE) on Ci8 cartridges. Aliquots o f the extracts were analysed by LC with UV detection at 298 nm. The CCa values ranged between maximum residue limit (MRL) + 12% and MRL + 25% and the CCP ranged between MRL + 25% and MRL + 45%. The triphenylmethane dyes were extracted from salmon with acetonitrile and pH 3 buffer, extracts were cleaned up using cation-exchange SPE on sulphonic acid (SCX) cartridges and the sample extracts were analysed by liquid chromatography tandem mass spectroscopy (LC-MS/MS). CCa for malachite green, leucomalachite green, crystal violet and leucocrystal violet were 0.17, 0.15, 0.40 and 0.17 iig-kg'1 respectively and CCP were 0.30, 0.35, 0.80 and 0.32 ng.kg 1 respectively.
All research undertaken in this thesis was published in peer reviewed journals. This work has made a significant contribution to residues science as more novel methods have become available for surveillance of these drugs at national and international level. The methods developed in this research also provide a legal basis for prosecuting individuals who use these veterinary products without adhering to EU legislation. Ultimately the work enhances food safety as methods developed help to eliminate the hazards associated with drug residues entering the food chain
Klinische Anatomie; Van A(natomie) naar Beter
Full text linkNiet UB, maar tijdelijk ter bevordering van de PDF bestanden in het Leids Repositorium
Produção de conserva de mexilhões (Perna perna) em embalagem flexível: avaliação sensorial e instrumental da textura
Full text linkDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Alimentos.O objetivo deste trabalho foi avaliar o efeito do processamento sobre a microbiologia e as propriedades texturais e sensoriais do mexilhão (Perna perna) armazenado em embalagem flexível (polietileno) a temperatura ambiente. As soluções variam na concentração de ácido lático e sal de cozinha (NaCl), onde cada variação foi chamada de ensaio, num total de nove ensaios. Após a imersão dos mexilhões na solução, os mesmos foram acondicionados em embalagem plástica termorresistente e seladas a vácuo. As embalagens foram imersas em água em ebulição por 30 minutos. A avaliação microbiológica dos mexilhões apresentaram limites aceitáveis para Coliformes totais, Salmonella spp e S. aureus, atendendo os limites estabelecidos pela Agência Nacional de Vigilância Sanitária. Os resultados das bases voláteis totais após 90 dias de estocagem indicaram bom estado de conservação do produto, estando também abaixo do limite estabelecido pela legislação brasileira. As análises mostraram que o produto é próprio para o consumo humano. Os resultados da análise instrumental de textura foram comparados com o mexilhão pré-cozido. Para avaliar as características sensoriais do produto, foi realizado o teste de aceitação, com 25 consumidores, utilizando uma escala hedônica de nove pontos. A análise sensorial foi realizada com os ensaios 4, 5, 6, 7, 8 e 9 com 30 dias de estocagem, não havendo diferença significativa (p < 0,05) entre as amostras, com índice médio de aceitabilidade de 67,26 %
The Virtual Surgical Pelvis: Anatomy Visualization for Education and Surgical Planning
No full textThis thesis deals with visualizing anatomical data for medical education and surgical planning purposes. To this end, we have developed a detailed virtual atlas, the Virtual Surgical Pelvis (VSP),which unifies surgically relevant knowledge on pelvic anatomy. We provide methods to share the knowledge contained in the VSP for educational purposes, and to visualize the VSP in the context of individual patients for pre-operative planning purposes.Chapter 2 deals with a representation developed to unify spatial and non-spatialanatomical knowledge. Via this representation, it is possible to store, access and visualize these heterogeneous datasets through a shared coordinate system. This allows us to construct the VSP atlas, a process which we describe in detail in Chapter 3, where we also detail the application potential of the VSP. We present several examples of the VSP mapped to clinical pre-operative MRI scans, as examples of how the VSP can be used to enrich clinical data with surgically relevant information that is not available from the scans themselves.To share the VSP for educational purposes, we present an online tool, the Online Anatomical Human (OAH) in Chapter 4. OAH runs directly in the browser and can be used to explore the complex relation between 2D and 3D anatomy. Furthermore, annotations can be added directly on the 3D structures for quizzing purposes, or to enrich the VSP further with annotations performed by experts. The OAH was successfully deployed in aMassiveOpenOnline Course (MOOC), where thousands of studentsworldwide used the application to study pelvic anatomy.While the VSP is based on multiple datasets, it does not include all potential topological anatomical variations in branching structures such as vessels and nerves. Illustrations and text are traditionally used by medical specialists to study these variations, but it is difficult to compare complex variations in such illustrations. Therefore, in Chapter 5 we present an interactive visualization application for anatomical variations, which allows the user to compare and explore variations of branching structures interactively for educational purposes. With methods inspired by graph theory, users can intuitively select groups of variations, based on a similarity measure, and compare local differences.In Chapter 6, we present a state-of-the-art report on multimodal medical visualization. We describe the basics of medical image acquisition, and the clinical workflow for dealing with such data. We discuss suitable rendering and visualization techniques appropriate for rendering multiple modalities. The core contribution of this work is a taxonomy based on the multimodal medical visualization applications so far, the visualization techniques they employ, and the medical domain context. Additionally, we provide an outlook on open problems and potential future research directions.To make the VSP patient-specific and to enrich the VSP with more datasets, registration is needed. Unfortunately, current registration software is often difficult to use for non-medical-imaging-experts. In Chapter 7 we present a new registration application, RegistrationShop, that allows user to register 3D medical image datasets based on 3D visualizations and simple interactive transformation tools. Based on real-time visual feedback via comparative visualization techniques, users can inspect the current registration result and iteratively improve the alignment. Besides basic interactive transformation tools, we propose a novel way of placing corresponding landmark-pairs in 3D volumes.After combining the VSP atlas with patient-specific pre-operative MRI scans, we visualize the results in an interactive application for surgical planning aimed at pelvic oncological procedures, entitled PelVis, which is described in Chapter 8. We present visualization methods to represent context, target, and risk structures for surgical planning of the Total Mesorectal Excision (TME) procedure. We employ distance-based and occlusion management techniques to represent the patient-specific pathology and anatomy. Furthermore, we visualize the confidence in the registration outcome in relation to the distance of the target structure to the risk zones.The research described in this thesis was supported by the Dutch Technology Foundation STW via project 10903: “High-definition Atlas-based surgical planning for Pelvic Surgery”
A Community Perspective on Smart Grid Projects: Preselecting community-oriented smart grid project sites within Dutch neighborhoods for end-user flexible behavior potential
No full textWithin several testing grounds in The Netherlands, Decentralized System Operators (DSOs) test a variety of smart grid solutions in order to anticipate on expected peak load increase; Most future energy system scenarios point out issues related to the functioning of the grid. Examples are blackout risks and large voltage fluctuations, which occur due to peak load as a result of rising electricity peak demand (for example because of electric vehicles) as well as decentralized electricity generation. The classic solution for the DSO to handle peak load are grid reinforcements which are costly and do not support the uptake of sustainable energy technology. In effect, the DSOs assess the suitability of alternative, possibly cheaper and more sustainable solutions for the future energy system. One measure is to mitigate peak load by incentivizing time-flexible electricity consumption. Through stimuli triggering a behavioral reaction, the DSO wishes to make residents adaptive end-users. Within previous pilot projects, DSOs predominantly assessed the effectiveness of stimuli related to electricity pricing schemes and real-time consumption information on end-user flexibility behavior.....Technology, Policy and ManagementEnergy & Industr
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