11 research outputs found
Invasive validation of a new oscillometric device (Arteriograph) for measuring augmentation index, central blood pressure and aortic pulse wave velocity
No full textBackground The importance of measuring aortic pulse wave velocity (PWVao), aortic augmentation index (Aix) and central systolic blood pressure (SBPao) has been shown under different clinical conditions; however, information on these parameters is hard to obtain. The aim of this study was to evaluate the accuracy of a new, easily applicable oscillometric device (Arteriograph), determining these parameters simultaneously, against invasive measurements. Methods Aortic Aix, SBPao and PWVao were measured invasively during cardiac catheterization in 16, 55 and 22 cases, respectively, and compared with the values measured by the Arteriograph. Results We found strong correlation between the invasively measured aortic Aix and the oscillometrically measured brachial Aix on either beat-to-beat or mean value per patient basis (r=0.9, P<0.001; r=0.94, P<0.001), which allowed the noninvasive calculation of the aortic Aix without using generalized transfer function. Similarly strong correlation (r=0.95, P<0.001) was found between the invasively measured and the noninvasively calculated central SBPao; furthermore, the BHS assessment of the paired differences fulfilled the 'B' grading. The PWVao values measured invasively and by Arteriograph were 9.41 +/- 1.8 m/s and 9.46 +/- 1.8 m/s, respectively (mean +/- SD); furthermore, the Pearson's correlation was 0.91 (P<0.001). The limits of agreement were 11.4% for aortic Aix and 1.59 m/s for PWVao. Conclusion Aix, SBPao and PWVao, measured oscillometrically, showed strong correlation with the invasively obtained values. The observed limits of agreement are encouragingly low for accepting the method for clinical use. Our results suggest that the PWVao values, measured by Arteriograph, are close to the true aortic PWV, determined invasively. J Hypertens 28: 2068-2075 (C) 2010 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins
Are Concerns About Leveraged ETFs Overblown?∗
No full textNOTE: Staff working papers in the Finance and Economics Discussion Series (FEDS) are preliminary materials circulated to stimulate discussion and critical comment. The analysis and conclusions set forth are those of the authors and do not indicate concurrence by other members of the research staff or the Board of Governors. References in publications to the Finance and Economics Discussion Series (other than acknowledgement) should be cleared with the author(s) to protect the tentative character of these papers
In Vitro Longitudinal Relaxivity Profile of Gd(ABE-DTTA), an Investigational Magnetic Resonance Imaging Contrast Agent.
No full textMRI contrast agents (CA) whose contrast enhancement remains relatively high even at the higher end of the magnetic field strength range would be desirable. The purpose of this work was to demonstrate such a desired magnetic field dependency of the longitudinal relaxivity for an experimental MRI CA, Gd(ABE-DTTA).The relaxivity of 0.5mM and 1mM Gd(ABE-DTTA) was measured by Nuclear Magnetic Relaxation Dispersion (NMRD) in the range of 0.0002 to 1T. Two MRI and five NMR instruments were used to cover the range between 1.5 to 20T. Parallel measurement of a Gd-DTPA sample was performed throughout as reference. All measurements were carried out at 37°C and pH 7.4.The relaxivity values of 0.5mM and 1mM Gd(ABE-DTTA) measured at 1.5, 3, and 7T, within the presently clinically relevant magnetic field range, were 15.3, 11.8, 12.4 s-1mM-1 and 18.1, 16.7, and 13.5 s-1mM-1, respectively. The control 4 mM Gd-DTPA relaxivities at the same magnetic fields were 3.6, 3.3, and 3.0 s-1mM-1, respectively.The longitudinal relaxivity of Gd(ABE-DTTA) measured within the presently clinically relevant field range is three to five times higher than that of most commercially available agents. Thus, Gd(ABE-DTTA) could be a practical choice at any field strength currently used in clinical imaging including those at the higher end
Longitudinal relaxivity profile of Gd(ABE-DTTA) and Gd-DTPA.
No full textA: The field dependency of the longitudinal relaxivity of 4 mM Gd-DTPA (circles) and 0.5 mM and 1 mM Gd(ABE-DTTA) (diamonds and squares, respectively) acquired with NMRD is shown. B: The relaxivity of Gd(ABE-DTTA) and GD-DTPA obtained on a series of static field MRI and NMR instruments listed in Table 1, as a function of magnetic field strength is shown. All measurements were carried out at 37°C and pH 7.4.</p
The MRI characteristics of the no-flow region are similar in reperfused and non-reperfused myocardial infarcts: an MRI and histopathology study in swine
No full textLongitudinal relaxivity data (s<sup>-1</sup>mM<sup>-1</sup>) of Gd(ABE-DTTA) and Gd-DTPA obtained on NMRD, MRI and NMR instruments are shown along with the corresponding field strength (Tesla) and proton Larmor frequency (MHz).
No full textLongitudinal relaxivity data (s-1mM-1) of Gd(ABE-DTTA) and Gd-DTPA obtained on NMRD, MRI and NMR instruments are shown along with the corresponding field strength (Tesla) and proton Larmor frequency (MHz).</p
List of the MRI and NMR equipment used in our studies.
No full textList of the MRI and NMR equipment used in our studies.</p
Children Don’t Like Eating What They’re Supposed to Eat… A Study of Public Catering for Children in Hungary from a Historical Perspective
No full textChildhood nutrition is an important element of lifestyle research, since the regularity and nutritional
content of our meals as children, and the way in which they are eaten, determine our physical and mental
health throughout our lives. Prior to 2018, there was no basic interdisciplinary research on this topic in
Hungary, thus to fill the gap, an interdisciplinary research group was established in 2018 at the Institute of
Ethnography, which carried out nationwide research. The present study is based on fieldwork undertaken
by the author in two schools — the János Lenkey Primary School in Eger (formerly Primary School No. 1)
and the Tamás Bolyki Primary School in Ózd — as well as a large amount of information gleaned from
questionnaires and interviews. My research was also extended in terms of a historical and geographical
perspective: I studied archival sources and expanded the field of my investigations by including Salgótarján,
a research location familiar from my earlier research, which provided a vantage point alongside Ózd and
Eger, as a third city typical of Northern Hungary. Public catering for children has undergone significant
changes in the last six to seven years, although prior to this it had appeared relatively uniform, in line with
the ingredients available at the time. The obligation to provide public catering and the general obligation to
work, which began in the Rákosi era and culminated in the Kádár era, significantly changed family eating
habits. Traditional elements typical of a particular locality disappeared as the globalization efforts of socialism were accomplished. The ever-decreasing amount of time devoted to preparing, cooking, and
consuming food moved society in the direction of canteens, fast-food restaurants, and later, after the regime
change, global fast-food chains. Education on proper nutrition is not currently part of academic teacher
training, thus for want of a better alternative, teachers organize children’s school meals based on their own
experience and socialization or following the school’s regulations (where they exist), without having a
unified concept. The number of meals eaten at home has been reduced to light breakfasts, lunches, and dinners, with families mostly sitting down together at the table for dinner, when they often consume ready
meals. Lack of contact with foodstuffs and with the person preparing the food has a negative impact on
children’s psychological development. Relying on extensive basic research and participant observation, and
through the joint efforts of specialists from several fields of the social sciences, a significant improvement
could be achieved in both public catering and education on healthy nutrition
