268 research outputs found
DEBORA: Developing an Interface to Support Collaboration in a Digital Library
No full textInterfaces to library systems have largely failed to represent the in-herently collaborative nature of information work. This paper describes how collaborative functionality is being implemented as part of the DEBORA project to provide access to digitised Renaissance documents. Work practices of users of Renaissance documents are described and the collaborative features of the client software are outlined. Functionalities discussed include annotation, the creation of virtual books and the inclusion of user-supplied metadata
On the avant-garde : Bruno Schulz and Debora Vogel
No full textIn his recent book devoted to the study of Schulz, Michał Paweł Markowski rebukes the scholars of Schulz that they have ignored the indebtedness of the write r in Hegel's philosophy, and at the same time he claims that it is hard to find in Schulz any evidence that he had actually read the philosopher. The author of the article argues the contrary: Hegelian themes are treated by Schulz with an ironic distance, and it is certain the w rite r read Hegel as his
closest friend, Debora Vogel, devoted her PhD dissertation to the author of The Phenomenology of Spirit. The influence of Hegel can be rather seen in Vogel's writings, as she
was fascinated by the avant-garde idea of progress pursued by the anonymous masses. Seemingly Schulz the bumpkin is behind but in the long run he went ahead of his friend,
because unlike her he stressed the subjective aspect of the avant-garde revolution. Jarzębski Wobec awangardy: Bruno Schulz i Debora Vogel
Homogenization of conservation laws with oscillatory source and non-oscillatory data
No full textWe consider a scalar conservation law with oscillatory, periodic source term and with oscillatory initial data.
For possibly resonant initial data, we prove a corrector-type result for this problem, extending a previous one by
the author [Asymptotic Anal. 46 (2006), 53-79]. Here we can relax the assumption of well-prepared data
interessi sociali, concorrenza e pluralismo istituzionale nei servizi pubblici locali
No full textThe article tries to truce the connection between Pubblic Administration and Local Pubblic Services in the perspective of an institutional and social pluralism. Moving from the analysis of the changes occured to State intervention in economy and the ineraction of pubblic and private sector, the Author analyse the most recent reforms of Local Pubblic Services'legislation and the impact of the new costitutional federalism in the role of the different level of governament in managing and regulating Pubblic Service
Managing today's news media : audience first /
No full textThe business of journalism is in the midst of massive change. Managing Today's News Media: Audience First offers practical solutions on how to cope with and adapt to the evolving media landscape. News media experts Samir Husni, Debora Halpern Wenger, and Hank Price introduce a forward-looking framework for understanding why change is occurring and what it means to the business of journalism. Central to this new paradigm is a focus on the audience. The authors introduce "The 4Cs Strategy" to describe how customers, control, choice, and change are all part of a strategy for successful media organizations. Every chapter in the book relates to one or more of these four key principles: * Customer - Each platform must offer a unique experience to the customer. ...Includes bibliographical references (pages 203-210) and index.The business of journalism is in the midst of massive change. Managing Today's News Media: Audience First offers practical solutions on how to cope with and adapt to the evolving media landscape. News media experts Samir Husni, Debora Halpern Wenger, and Hank Price introduce a forward-looking framework for understanding why change is occurring and what it means to the business of journalism. Central to this new paradigm is a focus on the audience. The authors introduce "The 4Cs Strategy" to describe how customers, control, choice, and change are all part of a strategy for successful media organizations. Every chapter in the book relates to one or more of these four key principles: * Customer - Each platform must offer a unique experience to the customer. ...Description based on MARC record for print version
Violence, Chaos and Theophany in Habakkuk 3
No full textDivine violence often causes scandal, since the current image of divinity is one-dimensional, focused on features such as mercy, justice, forgiveness, etc. In reality, the Bible – First and New Testaments – is not afraid to present many faces of God, even those that are scandalous to us. The aim of this paper is to show the role of divine vio- lence in restoring order in the cosmos through the analysis of one of the most complex texts of the First Testament: Abakkuk 3. The restoration of the cosmic order is also the restoration of good and earthly justice. It is evident, however, that the world of the con- temporary reader is different from that of the author and his readers: textual analysis shows the distance that separates them and, at the same time, opens up a space of issues that solicits numerous questions about our way of place ourselves in front of religion and the divine, on our presuppositions and our expectations
Jean Baudrillard: cynism or truth?
No full textJean Baudrillard was one of the leading intellectuals of the twentieth century.
Baudrillard, who died on 6th March 2007 in Paris, conceived an acute observation and, on many
occasions, complex, ambiguous and difficult interpretation of contemporary society for him (and
us). Reassuming the observations that revolve around the French philosophy’s simulacra concept
during the 1960’s1, Baudrillard focused his attention on the relationship which is established
between this concept and the vast, symbolic horizon produced by the simulative condition present
in society.
Considered as being the father of the simulacra concept and according to this author, postmodern
society is differentiated from the previous period, the modern age, because of its being
organised in compliance with a new, simulation logic and on the continuous interchange of images
and signs. Differently, in fact, from modern society, which was structured according to the linear
and precise production logic; current society is based on the proliferation of codes, models and
signs and the new rules dictated by simulation.
Some, important thematic nucleuses and perspectives emerged from his analysis and shall be
expanded upon below
An Absent Narrator? The Structure of Narration in Debora Vogel's „Akacje kwitną. Montaże” („Acacias Bloom. Montages”)
No full textFor the author a polemics with the thesis concerning the “absence” of the narrator in Debora Vogel's novel Akacje kwitną. Montaże is the starting point for analysis of the narration structure of the work. The self-creating measures taken by the speaking subject, a distinct self-thematism and showing the very process of creating the novel world by means of proper techniques reveal the basic principle of the work's construction, which is the idea of creationism. At the same time these are manifestations of the experimental character of Vogel's fiction and of the peculiar game played by the narrator with the recipient with the use of tools typical of the novel
L'Agenda “Donne, pace e sicurezza” e la tutela dei diritti umani. Un bilancio a vent'anni dalla Risoluzione 1325 (2000)
No full textL'articolo propone una panoramica sull'adozione della ris. 1325 (2000) da parte del Consiglio di sicurezza delle Nazioni Unite in occasione del ventesimo anniversario dalla sua adozione. La risoluzione è uno dei documenti più importanti del Consiglio, sebbene non giuridicamente vincolante, ed ha creato la cd. Agenda "Donne, pace e sicurezza". L'elaborato si propone di sottolineare i profili giuridici di rilievo della risoluzione e delle successive risoluzioni che compongono il corpus normativo dell'Agenda. In particolare, nell'articolo si evidenziano i profili giuridici in materia di diritti umani, nello specifico dei diritti umani delle donne, dimostrando che sia la ris. 1325 (2000) che l'Agenda "Donne, pace e sicurezza" nel suo complesso debbano incardinarsi all'interno del framework normativo della tutela dei diritti umani in quello che l'autore chiama "il nuovo trinomio nell'equazione dei diritti umani".The article provides an overview of the adoption of United Nations Security Council Resolution 1325 (2000) in view of the 20th anniversary of its adoption. Resolution 1325 (2000) is one of the most important resolutions of the UNSC even if not legally binding and has created the so called "Women, Peace and Security" Agenda. This paper aims at highlighting the relevant legal aspects of the Resolution and the following ones which constitutes the legal corpus of the Agenda. In particular, his paper highlights the legal aspects of the international protection of human rights, specifically women’s human rights, and shows that it both Resolution 1325 (2000) and also the "Women, Peace and Security" Agenda as a whole should be enshrined within the legal framework of the protection of human rights in what the author has called "the new trinomial in the equation of human rights"
LPA₁ and LPA₂ receptors as new therapeutic targets for the treatment of central nervous system pathologies
No full textTesis inédita de la Universidad Complutense de Madrid, Facultad de Ciencias Químicas, Departamento de Química Orgánica, leída el 05-05-2017Los lisofosfolípidos son derivados lípidicos con funciones tanto estructurales como de señalización, por lo que juegan un papel fundamental en humanos y otros mamíferos. El análisis de lisofosfolípidos en fluidos humanos de pacientes con diferentes condiciones patológicas revela no sólo la importancia de los lisofosfolípidos y de sus receptores en enfermedades humanas, sino también sus potenciales aplicaciones como biomarcadores y/o dianas terapéuticas.1,2 Entre ellos, destaca el ácido lisofosfatídico (LPA) debido a su implicación en la regulación de procesos fisiológicos y patológicos de importancia a través de la activación de sus receptores correspondientes LPA1–6,3-5 todos ellos pertenecientes a la superfamilia de los receptores acoplados a proteínas G (GPCRs). El LPA regula una amplia variedad de actividades biológicas, especialmente en el desarrollo y el funcionamiento del sistema nervioso.6,7 Considerando los numerosos efectos producidos por el LPA en diferentes tipos celulares del sistema nervioso y la sobreexpresión de los receptores de LPA como consecuencia de un daño neuronal observado tanto en ratones como en humanos, es probable que el LPA regule aspectos esenciales en la reorganización celular después de un trauma neuronal.8 Entre todas las neuropatologías donde el LPA juega un papel importante, el dolor neuropático9-13 y el daño medular14-16 son condiciones con una elevada incidencia y altamente incapacitantes, que actualmente carecen de terapias específicas. En este contexto, los receptores LPA1 y LPA2 se han relacionado con estas patologías,17,18 pero la falta de agonistas y antagonistas potentes y selectivos ha dificultado el estudio de sus funciones específicas. Por tanto, en este trabajo, hemos abordado el desarrollo de ambos tipos de compuestos para así tratar de esclarecer la función de los receptores LPA1 y LPA2 en el dolor neuropático y en el daño medular...Lysophospholipids (LPs) are cell membrane lipid derivatives that also act as extracellular signals and play important roles in humans and other mammals. Analysis of LPs in human body fluids from subjects with different pathophysiological conditions reveal not only the relevance of LPs and their receptors in human diseases, but also their potential application as biomarkers and/or therapeutic targets.1,2 Among them, lysophosphatidic acid (LPA) stands out as a molecule that elicits a plethora of biological effects by binding to specific G protein-coupled receptors: LPA1–6 receptors.3-5 LPA regulates a wide variety of biological activities, notably within the developing and adult nervous system.6,7 Considering the pleiotropic effects of LPA on many nervous system cell types, together with data showing localized up-regulation of LPA receptors after injury in mice and humans, it is likely that LPA regulates essential aspects of the cellular reorganization after neural trauma.8 Among all neuropathologies where LPA plays an important role, neurophatic pain (NP)9-13 and spinal cord injury (SCI)14-16 are high incidence and seriously disabling conditions which currently lack specific pharmacological therapies. In this context, LPA1 and LPA2 receptor subtypes have been functionally linked to many neural processes associated to these pathologies,17,18 but the lack of potent and selective agonists and antagonists has impaired the delineation of their specific role. Hence, we have focused our efforts on the development of such agents to clarify the biological role of LPA1 and LPA2 receptors in NP and SCI...Depto. de Química OrgánicaFac. de Ciencias QuímicasTRUEunpu
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