214,531 research outputs found
A Corrected Proof of the Stochastic Verification Theorem within the Framework of Viscosity Solutions
No full textWe present a full and corrected proof of the stochastic verification theorem that was first obtained by Zhou, Yong, and Li [SIAM J. Control Optim., 35 (1997), pp. 243--253]
FIGURE 3. Carex daxinensis Y. Y. Zhou & X. F in Notes on Carex (Cyperaceae) from China: three new species
No full textFIGURE 3. Carex daxinensis Y. Y. Zhou & X. F. Jin, sp. nov. (A) habit; (B) staminate scale; (C) pistillate scale; (D) perigynium; (E) achene (drawn by Xiao-Feng Jin from holotype in HTC).Published as part of Zhou, Ying-Ying & Jin, Xiao-Feng, 2014, Notes on Carex (Cyperaceae) from China: three new species, pp. 133-140 in Phytotaxa 164 (2) on page 136, DOI: 10.11646/phytotaxa.164.2.7, http://zenodo.org/record/513266
Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancy
Full text linkMaternal endothelial dysfunction in preeclampsia is associated with increased soluble fms-like tyrosine kinase-1 (sFlt-1), a circulating antagonist of vascular endothelial growth factor and placental growth factor. Angiotensin II (Ang II) is a potent vasoconstrictor that increases concomitant with sFlt-1 during pregnancy. Therefore, we speculated that Ang II may promote the expression of sFlt-1 in pregnancy. Here we report that infusion of Ang II significantly increases circulating levels of sFlt-1 in pregnant mice, thereby demonstrating that Ang II is a regulator of sFlt-1 secretion in vivo. Furthermore, Ang II stimulated sFlt-1 production in a dose- and time-dependent manner from human villous explants and cultured trophoblasts but not from endothelial cells, suggesting that trophoblasts are the primary source of sFlt-1 during pregnancy. As expected, Ang II-induced sFlt-1 secretion resulted in the inhibition of endothelial cell migration and in vitro tube formation. In vitro and in vivo studies with losartan, small interfering RNA specific for calcineurin and FK506 demonstrated that Ang II-mediated sFlt-1 release was via Ang II type 1 receptor activation and calcineurin signaling, respectively. These findings reveal a previously unrecognized regulatory role for Ang II on sFlt-1 expression in murine and human pregnancy and suggest that elevated sFlt-1 levels in preeclampsia may be caused by a dysregulation of the local renin/angiotensin system
Drag reduction in a turbulent boundary layer using periodic blowing through one array of streamwise slits
No full textActive drag reduction of a turbulent boundary layer has been experimentally investigated using periodic blowing through one array of streamwise slits. Local skin-friction drag exhibits a strong dependence on control parameters, including the blowing amplitude A+ and frequency f +. A maximum drag reduction of almost 70% has been achieved at x+=33 downstream of the actuators. The near-wall structure under control are measured using smoke-wire flow visualization, hot-wire and PIV techniques. All the results point to a pronounced change in the structure of the boundary layer and a significant increase of the mean energy dissipation rate
Gongdu Zhou (trad. Chinese by Jorge Olivera and Yuqi Wang)
No full textEn los poemas de Gongdu Zhou, podemos observar, sobre todo, la esencia de la belleza clásica china : la naturaleza, la simplicidad, la reflexión, filosofía, etc.In the poems of Zhou Gongdu, we can see, above all, the essence of Chinese classical beauty: nature, simplicity, reflection, philosophy, etc.Depto. de Literaturas Hispánicas y BibliografíaFac. de FilologíaTRUEpu
Cissampelos keniensis Y. D. Zhou & Q. F. Wang
No full textE Cissampelos keniensis Y.D.Zhou & Q.F.Wang — Habit: Liana. Habitat: LMWF; 2 000–2 300 m. Distribution: IIIc. Voucher: Kaburia Track, Alt. 2 241 m, 29 Jun. 2016, Zhou & Mbuni 16/14 (HIB, EA, PE). Reference: Zhou et al. (2017b).Published as part of Zhou, Ya-Dong, Mwachala, Geoffrey, Hu, Guang-Wan & Wang, Qing-Feng, 2022, Annotated checklist of the vascular plants of Mount Kenya, East Africa, pp. 1-108 in Phytotaxa 546 (1) on page 41, DOI: 10.11646/phytotaxa.546.1.1, http://zenodo.org/record/655046
Phospholipid meets all-Trans-retinal: The making of RPE bisretinoids
No full textThe lipid phase of the photoreceptor outer segment membrane is essential to the photon capturing and signaling functions of rhodopsin. Rearrangement of phospholipids in the bilayer accompanies the formation of the active intermediates of rhodopsin following photon absorption. Furthermore, evidence for the formation of a condensation product between the photolyzed chromophore all-trans-retinal and phosphatidylethanolamine indicates that phospholipid may also participate in the movement of the retinoid in the membrane. The downside of these interactions is the formation of bisretinoid-phosphatidylethanolamine compounds that accumulate in retinal pigment epithelial cells with age and that are particularly abundant in some retinal disorders. The propensity of these compounds to negatively impact on the cells has been linked to the pathogenesis of some retinal disorders including juvenile onset recessive Stargardt disease and age-related macular degeneration.-Sparrow, J. R., Y. Wu, C. Y. Kim, and J. Zhou. Phospholipid meets all-trans-retinal: the making of RPE bisretinoids. Copyright �� 2010 by the American Society for Biochemistry and Molecular Biology, Inc
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