3,463 research outputs found
Letter from Cy Donner to Michi Weglyn, June 2, 1967
No full textA letter from Cy Donner to Michi Weglyn encouraging her to come out to California to talk to producers about two shows called "Youthquake" and "Pretty Talk".These materials are from box 73 and 74 of the Frank Chin Papers. The Frank Chin Papers contain personal and professional correspondence between Frank Chin and Michi Weglyn relating to particular projects on which either author was working as well as files related to the Day of Remembrance Tribute to Michi Weglyn
Targeting Telomere Dynamics as an Effective Approach for the Development of Cancer Therapeutics [Corrigendum]
No full textTao HY, Zhao CY, Wang Y, Sheng WJ, Zhen YS. Int J Nanomedicine. 2024;19:3805–3825.
The authors have advised that they neglected to include a funding statement on page 3820 of the published paper. The funding statement should read as follows.
Funding
This research was funded by the CAMS Innovation Fund for Medical Sciences (CIFMS) (2021-I2M-1-026).
The authors apologize for this error
Outcome of medium-dose VP-16/CY/TBI superior to CY/TBI as a conditioning regimen for allogeneic stem cell transplantation in adult patients with acute lymphoblastic leukemia
No full textThe choice of conditioning regimen before allogeneic stem cell transplantation (SCT) in patients with acute lymphoblastic leukemia (ALL) is important. We retrospectively compared outcomes of medium-dose VP-16/cyclophosphamide/total body irradiation (VP/CY/TBI) regimen and CY/TBI. Five hundred and twenty-nine patients (VP/CY/TBI: n = 35, CY/TBI: n = 494) who met all of the following criteria were compared: first time for SCT, aged 15-59 years; first or second complete remission at SCT; bone marrow or peripheral blood as stem cell source; and HLA phenotypically matched donor. Median age of the patients was 34 years, and patients who received VP/CY/TBI were younger (28 years vs. 34 years, P = 0.02). Cumulative incidences of relapse and non-relapse mortality (NRM) were higher for patients who received CY/TBI (P = 0.01 for relapse, P < 0.01 for NRM). After a median follow-up period of 36.9 months, 5-year overall survival (OS) rates were 82.2% in the VP/CY/TBI group and 55.2% in the CY/TBI group. OS, and disease-free survival (DFS) in the VP/CY/TBI group were shown to be significantly better by multivariate analysis [hazard ratio: 0.21 (95% confidence interval: 0.06-0.49) for DFS, hazard ratio: 0.25 (95% confidence interval: 0.08-0.59) for OS]. VP/CY/TBI was associated with a lower relapse rate and no increase in NRM, resulting in better survival than that in CY/TBI for adult ALL patients
A Recessive Lethal Gene, l-Cy, concealed in the Second Chromosome Balancer of Drosophila Melanogaster
No full textThe second chromosome balancer, SM 5[In(2(LR)SM 5)]Cy, has been used as a most useful tool to study the genetic variations in natural populations of Drosophila. melanogaster. The balancer suppresses recombination in almost whole region of the second chromosome since it has complicated inversions both in the right and left arms. It is lethal in the homozygous condition and it also has a dominant mutant, Cy, and several recessive mutations.Homozygous lethality has been explained by the presence of In(2 LR) or Cy itself. However, the cause of lethality is not necessarily clear. Recently, the author has found a recessive lethal gene in a natural population, which is allelic to these balancer chromosomes. In this short communication the author reports that the lethality of SM 5 chromosome in the homozygous condition is due to a recessive lethal gene, l-Cy (lethal Cy)
Weekly CY dose ingested.
No full text<p>Although both substrains received similar CY dose at the starting of the treatment period, voluntary drinking in subsequent weeks was higher in less symptomatic MRL +/+ than in MRL/lpr mice.</p
A Poetics of becoming: the mythography of Cy Twombly
No full textA Poetics of Becoming: The Mythography of Cy Twombly, centres upon Proteus, a painting made by the artist Cy Twombly in 1984. The chapter uses this particular work as a means of unpacking the artist's complex and manifold relationship with mythology. With regards to both the facture and the matiere of Proteus, the author argues that the visual poetics of the artist's work results from what is claimed to be the painting's "becoming
Accurate and robust feature-based homography estimation using HALF-SIFT and feature localization error weighting
No full textThe goal of homography estimation is to find global transformation between two images of the same scene taken from different viewpoints. The feature-based homography estimation method uses a local feature extractor, a RANSAC-like method and the Levenberg-Marquardt method to estimate the homography matrix. However, in practical applications, the accuracy and robustness of homography estimation are significantly affected by feature localization error. In this paper, we first use the HALF-SIFT method to compensate for localization error caused by the feature extraction method and use the covariance matrix to represent localization error caused by image noise. Then, we proposed a new inliers selection method named CW MLESAC and a new homography matrix refinement method named CW L-M to improve accuracy and robustness. Experimental results show that the proposed method is more accurate and robust under different noise levels and inlier ratios than state-of-the-art methods such as LMedS, RANSAC, MSAC and MLESAC
CY Students: Economic Desparity in the Formation of Racial Identity
No full textSubmitted by Tim McDonough ([email protected]) on 2008-06-04T19:31:37Z
No. of bitstreams: 1
ResearchProcess.doc: 60416 bytes, checksum: f98f8ef8abb0cbe4ec2582240eee44d0 (MD5)This project investigates whether racial identity within the Korean international student community is influenced by factors that had lead them to study in the United States. The aspect of racial identity being investigated focuses on individual’s perception of acceptance into various social networks on the University of Illinois campus. The author seeks to answer the following questions: How do people define their identity? How does appearance, nationality, ethnicity, and environment affect identity? Why do some CY students socialize only with the CY social networks while other CY students extend into main stream American social networks? How does economics factor into racial identity and does the “Push-Pull theory of migration” influence identity?Made available in DSpace on 2008-06-04T19:31:37Z (GMT). No. of bitstreams: 1
ResearchProcess.doc: 60416 bytes, checksum: f98f8ef8abb0cbe4ec2582240eee44d0 (MD5)
Previous issue date: 2008unpublishe
Investigation of heat transfer in metal-foam tubes
No full textThis thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Nowadays metallic foams attract increasing attention in making compact heat exchangers due to its advanced thermal properties. In this project, the performance of forced convection and flow boiling heat transfer in metal-foam tubes has been investigated experimentally and theoretically. Compared to those of plain tubes, the research results reveal that the use of metal foam can significantly enhance heat transfer capabilities due to its strong fluid mixing capability and the high surfacearea density. In present study, the heat transfer performance and flow resistance of R134a vapour flow in metal-foam tubes have been measured. The results show that both the microstructure of metal foams and tube/foam attaching methods (contact thermal resistance) can significantly affect the heat transfer performance. Compared to plain tubes, the use of metal foams could improve the heat transfer by 5-15 times. To examine the effect of different tube/foam combining methods on heat transfer, a group of metal-foam tubes with different attaching methods have been tested experimentally. Since no experimental result for two-phase heat transfer in metal foams can be found in the open literature despite their potential wide range applications, the boiling flow and heat transfer in horizontal metal-foam tubes are experimentally investigated. The results show that the two-phase flow resistance and heat transfer both increase as the pore size tends to be smaller for a given porosity. The boiling heat transfer will be enhanced by increasing the vapour quality for high mass flow rates, but it is not always true for low mass flow rates. This different heat transfer behaviour can be attributed to different flow patterns occurring inside the metal-foam tubes. The two phase flow pattern can be indirectly inferred from the cross-sectional wall surface temperature fluctuations and the temperature difference between the wall surface and refrigerant fluid. In addition to the experimental research, analytical and numerical investigations have been conducted to predict the heat transfer performance of forced convection and flow boiling heat transfer in these tubes. The effect of contact thermal resistance between the tube wall and metal foam structures was considered in the model. The results show that the overall thermal resistance of a metal-foam tube is a combination of the resistance of the metal-foam structure and the resistance between solid phase and fluid phase. The increase of relative density and the decrease of pore size of metal foams can reduce these resistances respectively. The thesis also reports the investigations of the effects of these parameters on enhancing the overall heat transfer performance. This was carried out through a detailed parametric analysis. The results show that the thermal performance of a metal-foam heat exchanger can be superior to that of conventional finned tube heat exchangers.Funding was obtained from the UK Engineering and Physical Sciences Research Council
(EPSRC grant number: GR1T24364/01) to provide fund for the project, Brunel
University (Brief Award, WAE-DPA301)
Behavioural effects of chronic exposure to CY/sucrose solution.
No full text<p>(A) Chronic immunosuppression reduced step-down latency in diseased MRL/lpr mice, but had the opposite effect on congenic controls. (B) In addition to the previously-documented substrain differences in sucrose consumption <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0100684#pone.0100684-Sakic3" target="_blank">[24]</a>, CY had a significant detrimental effect on the performance in both groups. (C) Although a trend was noted, CY could not abolish previously-reported differences in overall floating in the forced swim test <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0100684#pone.0100684-Sakic2" target="_blank">[23]</a>. (D) Prolonged immunosuppression improved spontaneous ambulatory activity in MRL/lpr mice, but had a detrimental effect on MRL +/+ controls. (E) Conversely, CY exposure significantly improved (but did not normalize) running wheel activity in MRL/lpr mice.</p
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