186,207 research outputs found

    Oxygen reserve index to predict oxygen status in anaesthetized dogs

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    Oxygen reserve index (ORi) is a non-invasive continuous parameter ranging from 0 to 1 that positively correlates with arterial oxygen content (PaO2) between 100-200 mmHg in humans. This prospective study investigated the relationship of ORi with PaO2, and its use to predict oxygen content in dogs. In 21 anaesthetised mechanically ventilated healthy dogs undergoing elective procedures, PaO2 was measured by a blood gas analyser and at the time of blood collection the ORi recorded by Masimo multi-wavelength pulse CO-oximeter. Pearson coefficient (r) was used to assess the correlation between ORi and PaO2. To identify if factors known to affect the pulse oximeter reading, such as the weight, local perfusion, pH, PaCO2, and temperature, influenced ORi measurements, paired data were fitted in a linear model and the correlation between the model residuals and the confounders was calculated. Youden index was used to identify the ORi value that predicted PaO2 ≥ 150 mmHg with the highest sensitivity and specificity. A total of 51 paired measurements of ORi and PaO2 were collected, and a moderate positive correlation (r = 0.6) was found. Plethysmographic curve appeared to influence the accuracy of ORi rather than the perfusion index. Only body weight mildly affected ORi measurements (r = 0.48, p < 0.05). An ORi ≥ 0.48 indicated a PaO2 ≥ 150 mmHg with as sensitivity of 87%. The oxygen reserve index may be used to titrate oxygen administration in anaesthetised dogs, although it does not replace blood gas analysis for arterial oxygen content measurement

    Constraining the Accretion Geometry of the Intermediate Polar EX Hya Using NuSTAR, Swift, and Chandra Observations

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    In magnetically accreting white dwarfs, the height above the white dwarf surface where the standing shock is formed is intimately related with the accretion rate and the white dwarf mass. However, it is difficult to measure. We obtained new data with NuSTAR and Swift that, together with archival Chandra data, allow us to constrain the height of the shock in the intermediate polar EX Hya. We conclude that the shock has to form at least at a distance of about one white dwarf radius from the surface in order to explain the weak Fe Kα 6.4 keV line, the absence of a reflection hump in the high-energy continuum, and the energy dependence of the white dwarf spin pulsed fraction. Additionally, the NuSTAR data allowed us to measure the true, uncontaminated hard X-ray (12-40 keV) flux, whose measurement was contaminated by the nearby galaxy cluster Abell 3528 in non-imaging X-ray instruments.Fil: Luna, Gerardo Juan Manuel. Consejo Nacional de Investigaciónes Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Astronomía y Física del Espacio. - Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Astronomía y Física del Espacio; ArgentinaFil: Mukai, K.. National Aeronautics and Space Administration; Estados UnidosFil: Orio, M.. Università di Padova; ItaliaFil: Zemko, P.. Università di Padova; Itali

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    The ability of oxygen reserve index to detect mild hyperoxemia in mechanically ventilated dogs: a preliminary study

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    Introduction:Mild hyperoxemia in humans could be detected with the oxygen reserve index (ORi) for arterial partial pressure of oxygen (PaO2) between 100 and 200 mmHg. This study evaluated the correlation of ORi with PaO2 and its ability to detect mild hyperoxemia in dogs. Methods:This prospective observational study enrolled 23 adult anesthetized dogs undergoing elective procedures. The animals were ventilated under pressure-control ventilation with a peak inspiratory pressure of 10–12cm H2O and a respiratory rate adjusted to maintain normocapnia. Simultaneous measurements of ORi and PaO2 were collected, with a multi-wavelength pulse co-oximeter with a probe applied to the dog’s tongue, and a blood gas analyzer, respectively. Pearson correlation coefficient (r) was calculated between simultaneous measurements of ORi and PaO2. Youden index was used toidentify the ORi cutoff values predicting PaO2 hyperoxia thresholds ≥110, ≥120, ≥130, ≥140, and ≥150 mm Hg with the highest sensitivity and specificity. Diagnostic performances of ORi to detect the same hyperoxia thresholds were estimated using the area under the receiver operating characteristic curve (AUROC).The effects of perfusion index (PI),body temperature, arterial blood pH, partial pressure of carbon dioxide (pCO2), lactatemia, and hemoglobin on AUROC were evaluated. Results: A total of 56 paired measurements of ORi and PaO2 were collected. Mean PaO2 value was 148.8 ±32.48 mm Hg and mean hemoglobin was 12.58±1.84 g/dL. A moderate positive correlation (r=0.53,P<0.001) between ORi and PaO2 was found. The ORicutoff value with the highest sensitivity (91%) was 0.3, indicating PaO2 ≥120 mm Hg, with 70% specificity and AUROC=0.84 (95%CI=0.68–1.01). The ORi value cutoff with the highest specificity (86%) was 0.6, indicating PaO2≥140 mm Hg, with 60% sensitivity and AUROC=0.79 (95% CI=0.67–0.91). The AUROCs of ORito detect hyperoxia thresholds tended to increase with decreasing blood pH, PI, and lactatemia and with increasing pCO2 and temperature, while hemoglobin did not affect diagnostic performance of ORi. Conclusions: ORi may detect mild hyperoxemia with PaO2 between120 and 140 mm Hg and limit excessive hyperoxia in mechanically ventilated dogs, although it does not replace blood gas analysis for assessment of oxygenation

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Withdrawn by Author

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    &lt;p&gt;Withdrawn by Author&nbsp;&lt;/p&gt

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Dr. Edward P. Wimberly, ITC, July 2011

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    This video is a conversation with Dr. Edward P. Wimberly. Dr. Wimberly talks about his book, "No Shame in Wesley's Gospel: A Twenty-First Century Pastoral Gospel". Brad Ost, AUC Woodruff Library, is the interviewer

    Author Rights and Scholarly Publishing

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    Originally posted at http://blog.library.gsu.edu/2014/10/24/author-rights-and-scholarly-publishing/</p
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