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Διερεύνηση των επιπέδων ομοκυστεΐνης ορού και συσχέτισή της με άλλους παράγοντες καρδιαγγειακού κινδύνου σε τυχαίο, αντιπροσωπευτικό και στρωματοποιημένο δείγμα του γενικού πληθυσμού
Homocysteine levels are now considered as a strong and independent factor for cardiovascular disease through many and various mechanisms. However there are findings that do not really confirm or recognize tHcy´s importance in actually causing coronary artery diasease, while recent studies have considered Hcy more as a result than a cause of arteriosclerosis.The aim of this work was to investigate the associations between homocysteine levels (tHcy) and several cardiovascular risk factors, in a random sample of cardiovascular diasease-free people. From May 2001 to December 2002 we randomly enrolled 1514 adult men and 1528 women, without any evidence of cardiovascular or any other chronic disease. The sampling was stratified by the age – gender distribution of (census 2001) of the greater area of Athens. Hcy's values was proved to be higher for males than for females. Current smokers versus former smokers and never smokers tHcy's levels were also higher. Hcy was also associated with age and body mass index (BMI). Hcy's levels were highly associated with blood pressure, cigarette smoking, alcohol consumption and coffee drinking. A positive correlation was also observed between Apo-B, ApoA1, total cholesterol, LDL-cholesterol, triglycerides and tHcy. On the other hand we found an inverse correlation between endurance exercise, HDL-cholesterol and tHcy. Adherence of the traditional Mediterranean diet was associated with a reduction of the concentrations of tHcy. Our findings indicate a positive association between hostility and homocysteine levels. There was a dose–response relationship between the severity of depressive symptoms and the expression of inflammatory and coagulation markers as tHcy´s levels. Our findings cannot be evidences for causality; however they can state hypotheses that could be evaluated by other prospective studies in the future.Τα αυξημένα επίπεδα ομοκυστεΐνης θεωρούνται σαν ένας ισχυρός και ανεξάρτητος παράγοντας καρδιαγγειακού κινδύνου, μέσω διάφορων μηχανισμών. Παράλληλα υπάρχουν ευρήματα που δεν αναγνωρίζουν τον ρόλο της υπερομοκυστεϊναιμίας στη πρόκληση καρδιαγγειακής νόσου ή την θεωρούν αποτέλεσμα κι όχι αίτιο στεφανιαίας νόσου.Στην παρούσα εργασία εξετάσαμε τις πιθανές σχέσεις των επιπέδων ομοκυστεΐνης με διάφορους καρδιαγγειακούς παράγοντες κινδύνου, σε τυχαίο δείγμα ατόμων χωρίς ιστορικό καρδιαγγειακής νόσου.Συγκεκριμένα στο χρονικό διάστημα Μάϊος 2001 έως Δεκέμβριος 2002 πραγματοποιήσαμε τη μελέτη μας σε τυχαίο και αντιπροσωπευτικό δείγμα του νομού Αττικής,στρωματοποιημένο κατά φύλο και ηλικία, που το αποτελούσαν 1514 άνδρες και 1528 γυναίκες. Τα επίπεδα ομοκυστεΐνης (tHcy) βρέθηκαν υψηλότερα στους άνδρες σε σχέση με τις γυναίκες.Οι καπνιστές βρέθηκε να εμφανίζουν υψηλότερες τιμές tHcy σε σχέση με τους πρώην και τους μη-καπνιστές.Οι τιμές της tHcy διαπιστώθηκε ότι συσχετίζονται με την ηλικία και τον δείκτη μάζας σώματος(BMI) των ατόμων.Διαπιστώσαμε επίσης θετική συσχέτιση της tHcy με την αρτηριακή πίεση, το κάπνισμα τσιγάρων, τη χρήση αλκοόλ και τη λήψη καφέ.Εξάλλου θετική σχέση βρέθηκε και με την Apo-B, ApoA1, ολική χοληστερόλη, LDL-χοληστερόλη και τα τριγλυκερίδια.Αντίθετα διαπιστώσαμε αρνητική συσχέτιση της tHcy με την σωματική άσκηση και με τα επίπεδα HDL-χοληστερόλης.Η υιοθέτηση της Μεσογειακής διατροφής φάνηκε να ευνοεί την μείωση των επιπέδων της tHcy. Επίσης τα αποτελέσματα μας έδειξαν θετική συσχέτιση της tHcy με την επιθετικότητα των ατόμων.Τέλος διαπιστώσαμε δοσολογική σχέση μεταξύ των συμπτωμάτων της κατάθλιψης και της βαρύτητάς τους με δείκτες φλεγμονής και πήξης όπως π.χ η ομοκυστεΐνη.Τα ευρήματά μας σίγουρα δεν αποτελούν αποδείξεις αιτιολογικής συσχέτισης της υπερομοκυστεϊναιμίας με τη καρδιαγγειακή νόσο-γιά αυτό απαιτούνται νέες προοπτικές μελέτες-αλλά μπορεί να συμβάλλουν στην έρευνα για τον ρόλο της στη πρόκληση καδιαγγειακής νόσου
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
Author-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
In Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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