7 research outputs found
Une gueguere de cents and dans le golfe de Guinée
No full textA Guiné-Equatorial, um dos países pouco conhecidos do continente africano, é analisado por Max Liniger-Goumaz do ponto de vista das origens e da herança colonial. A máquina do Estado, os responsáveis políticos, os interesses locais e, principalmente, os interesses externos, são analisados segundo conexões com o esquema da autoridade local. O autor mostra ainda que as alterações ocorridas em termos do sistema de poder não correspondem a mudanças reais no plano político econômico.nuloEquatorial Guinea, one of the countries less known on the African Continent, is analyzed by Max Liniger-Goumaz the points of view on origins and heritance the colonial. The state machine, the responsible politicians, local interests and mainly foreign interests, are analyzed according to their connections with the scheme of local authority. The author still shows that chances done in the ruling system do not correspond to the real changes in the political economic plan
Computational Evidence for Laboratory Diagnostic Pathways: Extracting Predictive Analytes for Myocardial Ischemia from Routine Hospital Data
No full textBackground: Laboratory parameters are critical parts of many diagnostic pathways, mortality scores, patient follow-ups, and overall patient care, and should therefore have underlying standardized, evidence-based recommendations. Currently, laboratory parameters and their significance are treated differently depending on expert opinions, clinical environment, and varying hospital guidelines. In our study, we aimed to demonstrate the capability of a set of algorithms to identify predictive analytes for a specific diagnosis. As an illustration of our proposed methodology, we examined the analytes associated with myocardial ischemia; it was a well-researched diagnosis and provides a substrate for comparison. We intend to present a toolset that will boost the evolution of evidence-based laboratory diagnostics and, therefore, improve patient care. Methods: The data we used consisted of preexisting, anonymized recordings from the emergency ward involving all patient cases with a measured value for troponin T. We used multiple imputation technique, orthogonal data augmentation, and Bayesian Model Averaging to create predictive models for myocardial ischemia. Each model incorporated different analytes as cofactors. In examining these models further, we could then conclude the predictive importance of each analyte in question. Results: The used algorithms extracted troponin T as a highly predictive analyte for myocardial ischemia. As this is a known relationship, we saw the predictive importance of troponin T as a proof of concept, suggesting a functioning method. Additionally, we could demonstrate the algorithm’s capabilities to extract known risk factors of myocardial ischemia from the data. Conclusion: In this pilot study, we chose an assembly of algorithms to analyze the value of analytes in predicting myocardial ischemia. By providing reliable correlations between the analytes and the diagnosis of myocardial ischemia, we demonstrated the possibilities to create unbiased computational-based guidelines for laboratory diagnostics by using computational power in today’s era of digitalization
Interaction and external field quantum quenches in the Lieb-Liniger and Gaudin-Yang model
No full textA review of the solution of the Lieb-Liniger is given. Using the wave function, the dynamics after a quench with a time dependent interaction strength is studied. Directly calculating the overlaps of wave functions, an interaction strength linear in time is examined. Furthermore utilizing those overlaps and the so called Yudson representation a time periodic interaction strength is studied. Moreover the dynamics of the Lieb-Liniger model with an external homogenous field is analyzed. After giving a review of the solution of the Gaudin-Yang model, an outlook on how the wave function for the Gaudin-Yang model in an external homogenous field could be obtained is given.M.S.Includes bibliographical referencesby Stefan M. Groh
The developmental cell biology of Trypanosoma brucei
No full textTrypanosoma brucei provides an excellent system for studies of many aspects of cell biology, including cell structure and morphology, organelle positioning, cell division and protein trafficking. However, the trypanosome has a complex life cycle in which it must adapt either to the mammalian bloodstream or to different compartments within the tsetse fly. These differentiation events require stage-specific changes to basic cell biological processes and reflect responses to environmental stimuli and programmed differentiation events that must occur within a single cell. The organization of cell structure is fundamental to the trypanosome throughout its life cycle. Modulations of the overall cell morphology and positioning of the specialized mitochondrial genome, flagellum and associated basal body provide the classical descriptions of the different life cycle stages of the parasite. The dependency relationships that govern these morphological changes are now beginning to be understood and their molecular basis identified. The overall picture emerging is of a highly organized cell in which the rules established for cell division and morphogenesis in organisms such as yeast and mammalian cells do not necessarily apply. Therefore, understanding the developmental cell biology of the African trypanosome is providing insight into both fundamentally conserved and fundamentally different aspects of the organization of the eukaryotic cell
Quench dynamics of one dimensional multi-component quantum gases
No full textThis thesis studies the quench dynamics of strongly correlated quantum systems described by one dimensional integrable Hamiltonians. We develop the Yudson approach for such systems in terms of contour integrals allowing the expansion of arbitrary states in terms of the Bethe Ansatz eigenstates which in turn provides the means to calculate the time evolution of such observables as densities or noise correlations from any initial states. As a motivation to the present work, I present the state of art ultracold atom techniques and fundamental questions related to the quench dynamics. Then various Bethe ansatz solutions are discussed. This is followed by an introduction to the Yudson approach where advantages and difficulties are listed. As applications of the Yudson approach, I studied the nonequilibrium dynamics of the Lieb-Liniger model,(bosonic) Gaudin-Yang model, quenched from a Mott state with a super fluid Hamiltonian. Integration contours are specified for various models and different interactions. It is shown that the Yudson approach incorporates all free states and bound states into the contour, separating them apart sheds light on the validity of the String hypothesis. The result is affirmative for Lieb-Linger model, but not for the Gaudin-Yang model. Our calculations for the density and correlation shows that for interacting system, if the pre-quench state has negligible overlap among the particles, the system retains this feature after the quench. Particularly, normalized noise function c(z; -z) at the origin shows different stages. Shortly after the quench, the sign are different for attractive and repulsive interaction. Then they both quickly approaches the value where possibility to find both particles equals zero. Then the value increases gradually for attractive models, while c(0; 0) remains small for repulsive systems.Ph.D.Includes bibliographical referencesby Huijie Gua
Escalating environmental summer heat exposure—a future threat for the European workforce
No full textHeat exposure constitutes a major threat for European workers, with significant impacts on the workers’ health and productivity. Climate projections over the next decades show a continuous and accelerated warming over Europe together with longer, more intense and more frequent heatwaves on regional and local scales. In this work, we assess the increased risk in future occupational heat stress levels using the wet bulb globe temperature (WBGT), an index adopted by the International Standards Organization as regulatory index to measure the heat exposure of working people. Our results show that, in large parts of Europe, future heat exposure will indeed exceed critical levels for physically active humans far more often than in today’s climate, and labour productivity might be largely reduced in southern Europe. European industries should adapt to the projected changes to prevent major consequences for the workers’ health and to preserve economic productivity. © 2020, The Author(s)
The SCAR READER Project: toward a high-quality database of mean Antarctic meteorological observations
No full textA new dataset of monthly and annual mean near-surface climate data ( temperature, surface and mean sea level pressure, and wind speed) for the Antarctic region has been created using historical observations [ Scientific Committee on Antarctic Research ( SCAR) Reference Antarctic Data for Environmental Research ( READER)]. Where possible, 6-hourly surface synoptic and automatic weather station observations were used to compute the means. The ability to quality control the data at the level of individual observations has produced a more accurate series of monthly means than was available previously. At the time of writing, the mean data are available on the Internet (http://www.antarctica.ac.uk/met/programs-hosted.html). Data for 43 surface-staffed stations and 61 automatic weather stations are included in the database. Here, mean temperature, pressure, and wind speed data for 19 occupied stations with long records are provided
