117,434 research outputs found
Spotlight on COVID-19: from biology to therapy and prevention
No full textIn this COVID-19 Focus Issue, we highlight a collection of recently published The FEBS Journal articles that consider the broader aspects of the COVID-19 pandemic, ranging from the debunking of urban myths to highlighting some of the most pressing questions concerning SARS-CoV-2 infection, treatment, prevention and pathology. The collection comprises two review articles, six Viewpoints, two research papers and one commentary. We hope that these articles will provide readers with an informative and interesting overview that will promote further critical analysis of currently available data and observations on COVID-19
Spotlight on COVID-19: eighteen months on
No full textIn this Editorial, we highlight the contents of The FEBS Journal’s second Special Issue focussed on COVID-19. The issue covers a variety of aspects related to COVID-19, ranging from the most recent improvements in therapies and the significant impact of rapidly developed COVID-19 vaccines to the emergence of variants of SARS-CoV-2, the role of the immune system in the various stages of the disease and the impact of the disease in different organs. We hope that this collection of articles will give readers an informative and critical perspective on recent advances in understanding and treating COVID-19
Cerebrosides with antiproliferative activity from Euphorbia peplis L.
No full textTwo new cerebrosides have been isolated from the whole plants of Euphorbia peplis L. The structures were established by FT-IR spectroscopy, FAB MS, EI-MS, ESI-MS, 1D and 2D NMR spectroscopy. The structures of the cerebrosideswere characterized as 1-O-β-D-glycosides of phytosphingosines, which comprised a common long-chain base, (2S, 3S, 4R, 8Z)-2-amino-8 (Z)-octadecene-1,3,4-triol with 2-hydroxy fatty acids of varying chain lengths (C25, C22) linked to the amino group. The isolated compounds were shown to possess significant antiproliferative properties against cultured human tumor cell lines KB and IMR-32
Glicerolipidi: sintesi chemoenzimatica ed effetto della catena acilica sull’attività idrolitica della lipasi
No full textSynthesis and Application of High Molecular Weight Multifunctional Poly(Ethylene Glycol)s
No full textTrieste science & the city young: come crescere un cuore sano
No full textPossiamo fare qualcosa per mantenere il nostro cuore giovane e sano? Nel contesto del progetto CURIoSA (ComUnicaRe per crescere in SAlute, finanziato dalla Regione Autonoma Friuli Venezia Giulia), viene proposto un evento con esperti del mondo della scienza e dello sport sulle tematiche che hanno risvolti sull'attuazione di misure preventive delle malattie di maggiore impatto socio-sanitario (tumori e malattie cardiovascolari). Incontro a cura di ICGEB e Università di Trieste. Intervengono: Giorgio Faganello, dirigente medico SC Cardiovascolare e Medicina dello sport Azienda Sanitaria Universitaria Integrata di Trieste, Francesco Loffredo, docente di Scienze mediche applicate Università della Campania "L. Vanvitelli" di Napoli, head of Molecular Cardiology Unity ICGEB. Conduce Serena Zacchigna, group leader Cardiovascular Biology ICGEB, docente di Biologia molecolare Università di Trieste. Special guest: il gruppo musicale "Sindrome di MA
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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