1,721,168 research outputs found
8th International Congress of the NDPKinase/Nm23/awd Family-From Basic Science to Clinical Application-
No full textUSE OF MICRORNA-199b-5p IN MEDICAL AND DIAGNOSTIC FIELD
No full textThis invention concerns the use of MicroRNA-199b-5p in medical and diagnostic fields. Particularly, this invention concerns the use of the miR199b-5p in the anti-cancer therapy and as a histophatological and metastasis marker
Metastatic breast cancer: does prune make the tumor prone?
No full textIL CONVEGNO HA AVUTO SPEAKERS DI NATURA INTERNAZIONALE CHE HA PORTATO A CONFRONTO SCIENZIATI DA TUTTO IL MONDO CHE STUDIANO IL CARCINOMA MAMMARIO ED I SUOI SVILUPPI TERAPEUTICI
Biomarcatore per la rilevazione di cellule tumorali circolanti e relativi metodi e kit di rilevazione
No full textBiomarcatore per la rilevazione di metastasi di tumori e relativi metodi e kit di rilevazione
-----
L’invenzione concerne un biomarcatore per la rilevazione di metastasi di tumori come il tumore tumore del colon, dell’esofago, gastrico, della mammella, dei polmoni, medulloblastoma, della prostata, linfoma, melanoma, glioblastoma, carcinoma del pancreas, sarcoma, epatocarcinoma, mediante rilevazione del numero di copie e della variazione di espressione del gene erbB2 nei liquidi biologici di pazienti affetti dai tumori sopra elencati
H-prune enhance WNT and Notch canonical pathway in breast cancer; Metastatic breast cancer: does prune make the tumor prone?
No full text
Inibitori della migrazione cellulare mediata dal complesso tra h-prune e GSK-3 e relativi usi nella terapia antitumorale.
No full textThe invention concerns new inhibitors of cell migration mediated by h-prune-GSK-3 complex and uses thereof for the prevention and treatment of tumour metastases
Encyclopedia of Cancer 1st Edition (2008)
No full texthttp://www.springerlink.com/content/u2544p7368v26v60/accesso all'articolo.
Prune H stands for the human homologue of the Drosophila prune gene. Prune protein was initially identified in Drosophila, in which its mutation caused a brownish-purple “prune” eye color due to significant loss of drosopterins “red pigments,” compared to the bright red eye of the wild-type fly, thus explaining its mutant name.
Characteristics
Prune is appertaining to the DHH family phosphoesterase proteins including RecJ DNA repair Exonucleases, Pyrophosphatases (PPASEs) and Exopolyphospatases (PPX). The DHH super-family can be divided into two main groups on the basis of a C-terminal motif that is very well conserved within each group, but not across the groups. All the members of this super-family possess four other motifs that contain highly conserved charged residues predicted to be responsible for binding ions and catalyzing the phosphoesterase reaction. The most characteristic of these is the third motif, with the signature DHH ...
- …
