3,088 research outputs found

    Retour à Olbia : Conférence internationale, pour célébrer 200 années de fouilles à Olbia. 1994

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    Zhuravlev Denis, Zuev Vadim. Retour à Olbia : Conférence internationale, pour célébrer 200 années de fouilles à Olbia. 1994. In: Dialogues d'histoire ancienne, vol. 21, n°1, 1995. pp. 255-263

    Contrasting activity profile of two distributed cortical networks as a function of attentional demands

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    The original publication is available at http://www.jneurosci.orgThis work was supported by R01 grant MH-073610 from the National Institutes of Health to Denis Paré

    Is Tolerance Political? An Interview with Denis Lacorne

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    contribution à un site webDenis Lacorne is the author of "The Limits of Tolerance. Enlightenment Values and Religious Fanaticism" (Columbia University Press, 2019), the English translation of "Les limites de la tolérance" (Gallimard, awarded the Prix Montyon by the Académie Française). In his book, which is intellectually very inspiring because of the many questions it addresses and raises, Denis Lacorne traces the emergence of the notion of tolerance from its early thinkers to the Age of Enlightenment and finally questions the notion and its various understandings through more recent events in France and the United States. What is tolerance? Is tolerance political? Interview by Miriam Périer, CER

    Timing of impulses from the central amygdala and bed nucleus of the stria terminalis to the brainstem

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    The amygdala and bed nucleus of the stria terminalis (BNST) are thought to subserve distinct functions with the former mediating rapid fear responses to discrete sensory cues and the latter longer “anxiety-like” states in response to diffuse environmental contingencies. Yet, these structures are reciprocally connected and their projection sites overlap extensively. To shed light on the significance of BNST-amygdala connections, we compared the antidromic response latencies of BNST and central amygdala (CE) neurons to brainstem stimulation. Whereas the frequency distribution of latencies was unimodal in BNST neurons (~10 ms mode), that of CE neurons was bimodal (~10 and ~30 ms modes). However, after stria terminalis (ST) lesions, only short-latency antidromic responses were observed, suggesting that CE axons with long conduction times course through the ST. Compared to the direct route, the ST greatly lengthens the path of CE axons to the brainstem, an apparently disadvantageous arrangement. Since BNST and CE share major excitatory basolateral amygdala (BL) inputs, lengthening the path of CE axons might allow synchronization of BNST and CE impulses to brainstem when activated by BL. To test this, we applied electrical BL stimuli and compared orthodromic response latencies in CE and BNST neurons. The latency difference between CE and BNST neurons to BL stimuli approximated that seen between the antidromic responses of BNST cells and CE neurons with long-conduction times. These results point to a hitherto unsuspected level of temporal coordination between the inputs and outputs of CE and BNST neurons, supporting the idea of shared functions.The original publication is available at: http://jn.physiology.org/cgi/content/full/100/6/342

    Rehab Depot de la Plaine Saint-Denis

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    Redesign for workshop Atelier Revision Intermediaire at the Depot de la Plaine Saint-Denis with a rehabilitation center as new functionRMITArchitecture and The Built Environmen

    Der verschwundene Archipel : Die Geoarchäologie der Taman-Halbinsel unter dem Einfluss von Professor Hans-Joachim Gehrke

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    International audienceZwischen 2011 und 2021 umfasste das archäologische Projekt „Taman'“ unter der Leitung von Udo Schlotzhauer und Denis Zhuravlev auch einen bedeutenden geoarchäologischen Aspekt, gefördert von Hans-Joachim Gehrke, dem ehemaligen Direktor des Deutschen Archäologischen Instituts. Dank der Zusammenarbeit mit den Geomorphologen Helmut Brückner und Daniel Kelterbaum kam es zu völlig neuen Erkenntnissen, nicht nur für die Geowissenschaften, sondern auch für die Archäologie und Alte Geschichte. H. Brückner und D. Kelterbaum revolutionierten die gängige Meinung über die holozänen Meeresspiegelschwankungen des Schwarzen Meeres. Sie zeigten, dass die bis dahin postulierten Regressions-Transgressions-Zyklen – insbesondere die sog. Phanagoreische Regression zwischen etwa 800 und 200 v.Chr. – nicht stattgefunden haben und stattdessen der Meeresspiegel des Schwarzen Meeres während des Holozäns kontinuierlich gestiegen ist und nur lokal durch tektonische Prozesse beeinflusst wurde. Darüber hinaus belegen die Sedimente aus ihren Bohrungen auf der Taman'-Halbinsel die ehemalige Existenz eines Archipels aus vier Inseln westlich der Mündung des Kuban-Flusses seit der Bronzezeit. Durch den Abgleich zwischen geowissenschaftlichen sowie den reichen archäologischen Befunden mit alten und modernen Texten und Karten, die seit mehr als einem Jahrhundert von Ausgrabungen und Vermessungen gesammelt wurden, konnten wir ein kohärentes Szenario für die Identifizierung der meisten antiken und mittelalterlichen Orts- und Flussnamen erstellen sowie den historisch überlieferten mentalen Rahmen der Landschaftsbeschreibungen rekonstruieren. Daraus ergibt sich eine völlig neue Sicht auf die Entwicklung der Topographie der heutigen Taman'-Halbinsel. In diesem Beitrag erläutern wir beispielhaft die Folgen der neuen Erkenntnisse für die antike Stadt Kepoi und dem heutigen Ort Taman'. Wir zeigen, dass die archäologischen und historischen Zeugnisse mit der geographischen Rekonstruktion der Landschaft im Umfeld dieser milesischen Kolonie im asiatischen Teil des Kimmerischen Bosporus und dem modernen Ort Taman' vereinbar sind

    Severini e Denis

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    L'A. prende in esame i controversi rapporti tra i due artisti, nel primo decennio del secolo e, più tardi, nella produzione di carattere religioso. Severini risulta influenzato da Denis più di quanto sostenga negli scritti teorici. The Author examines the controversial relationships between the two artists, in the first decade of the century and later on, in their religious production. Severini appears influenced by Denis more than he declares in his theoretic writings

    The bed nucleus of the stria terminalis mediates inter-individual variations in anxiety and fear

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    While learning to fear stimuli that predict danger promotes survival, the inability to inhibit fear to inappropriate cues leads to a pernicious cycle of avoidance behaviors. Previous studies have revealed large inter-individual variations in fear responding with clinically anxious humans exhibiting a tendency to generalize learned fear to safe stimuli or situations. To shed light on the origin of these inter-individual variations, we subjected rats to a differential auditory fear conditioning paradigm where one conditioned auditory stimulus (CS+) was paired to footshocks whereas a second (CS-) was not. We compared the behavior of rats that received pre-training excitotoxic lesions of the bed nucleus of the stria terminalis (BNST) to that of sham rats. Sham rats exhibit a continuum of anxious/fearful behaviors. At one end of the continuum were rats that displayed a poor ability to discriminate between the CS+ and CS-, high contextual freezing, and an anxiety-like trait in the elevated plus maze (EPM). At the other end were rats that display less fear generalization to the CS-, lower freezing to context, and a non-anxious trait on the EPM. Although BNST-lesioned rats acquired similarly high levels of conditioned fear to the CS+, they froze less than sham rats to the CS-. In fact, BNST-lesioned rats behaved like sham rats with high discriminative abilities in that they exhibited low contextual fear and a nonanxious phenotype in the EPM. Overall, this suggests that inter-individual variations in fear generalization and anxiety phenotype are determined by BNST influences on the amygdala and/or its targets.Published in Journal of Neuroscience. Copyright Society for Neuroscience.Available from the Journal of Neuroscience: http://www.jneurosci.org

    Theta synchronizes the activity of medial prefrontal neurons during learning

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    Copyright, Learning & Memory Online by Cold Spring Harbor Laboratory Press http://www.learnmem.org/This material is based upon work supported by NIMH grant R01MH-073610.The published version of this article is online at http://www.learnmem.org/cgi/doi/10.1101/lm.93240

    Amygdala intercalated neurons are required for expression of fear extinction

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    Here we test the hypothesis that ITC neurons mediate extinction by lesioning them with a toxin that selectively targets cells expressing micro-opioid receptors (microORs).This is the author's version of an accepted paper for Nature. The published article can be found at the journal's web site: http://www.nature.com/nature
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