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Procedure alternative alla chirurgia nella correzione di alcune cardiopatie congenite. Stato attuale e prospettive.
Cogan Syndrome
To lead ophthalmologists to consider Cogan syndrome
when managing a patient presenting with keratitis or other ocular
inflammation accompanied by sensorineural hearing loss. Methods.
Seven patients affected by Cogan syndrome were studied: two
males and five females, ranging from 27 to 65 years of age (mean
age: 41 years). Subjects were evaluated for a period ranging from
22 to 46 months (mean follow up time: 29.2 months). All patients
were treated with immunosuppressive drug combination therapy
(IDCT). Results. Three patients were affected by classic Cogan
syndrome (i.e., vestibuloauditory symptoms and later sensorineural
hearing loss and interstitial keratitis). Four patients presented
atypical Cogan syndrome (i.e., sensorineural hearing loss and
chronic ocular inflammation such as uveitis, scleritis, conjunctivitis,
retinal vasculitis, etc.). Four of these patients had a late diagnosis.
Two of them were diagnosed when they already had a
cochlear implant, one with bilateral deafness underwent cochlear
implantation 1 year after the beginning of IDCT, one had severe
bilateral hearing loss that improved during the first year of IDCT,
and then rapidly worsened to total deafness in 1 month following
an episode of severe systemic hypotension. Three patients who had
an early diagnosis of Cogan syndrome had no worsening of vestibuloauditory
dysfunction during the follow up period. Conclusion.
Diagnosis of Cogan syndrome should not be overlooked by
ophthalmologists in all patients with recurrent ocular inflammatory
disease associated with vestibuloauditory symptoms. Early diagnosis
is essential to commence the appropriate immunosuppressive
therapy that may prevent permanent hearing loss and ocular
dysfunctio
Percutaneous balloon angioplasty in post-operative Fontan patients with pulmonary artery stenosis
L'angioplastica percutanea nel trattamento delle stenosi valvolari polmonari ed aortiche
Emangiomatosi epatica multinodulare con scompenso cardiaco ed evoluzione in epatopatia colostatica.
Emangiomatosi epatica con scompenso cardiaco congestizio ed evoluzione in epatopatia colostatica
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