1,354,059 research outputs found
Cystic lymphangioma in adult. a case report and a review of the literature
No full textCystic lymphangioma (CL) in adult is a very rare pathology. Its etiology remains unclear, but it is supposed to be congenital or to be a result of obstruction and lymph fluid retention of developing lymphatic vessels. It generally occurs in the head and neck region, probably because of the rich lymphatics in this area. It can be easily misdiagnosed with other cervicofacial masses. We present the case of a 56-year-old-female presented with a right-sided painless cervical swelling. Ultrasonography and magnetic resonance imaging were performed and a surgical complete removal was carried out. Histological examination revealed that the mass was composed by a variety of dilated lymph vessels involved in a fibrovascular stroma. Diagnose of CL was done. With this article, we want to highlight the features of CL and its role in the differential diagnoses of adults' cervicofacial masses
Diagnostic approach to a rare case of osteoid osteoma of the astragalus.
No full textA rare case of osteoid osteoma of the ankle of the left foot is discussed. Standard X-ray and MRI were negative. Triphasic bone scintigraphy followed by CT were performed. Combined clinical CT and scintigraphy findings were highly suggestive of osteoid osteoma. This diagnosis was confirmed on histology
Ifosfamide given by continous-intravenous infusion in association with vinorelbine in patients with antracycline-resistany metastatic breast cancer:A phase I-Ii clinical trial
No full textGoing Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
No full text“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Ifosfamide given by continous-intravenous infusion in association with vinorelbine in patients with antracycline-resistant breast cancer: A phase I-II clinical trial.
No full textBackground; Vinorelbine (VNR) is highly active in metastatic
breast cancer (MBC) and has shown an overall response rate
of 40%-50% as first-line treatment. /;; vitro, a synergy has been
observed between this drug and ifosfamide (IFX). In addition,
the pharmacokinetics of IFX suggest that it may have greater activity when given by continuous-intravenous infusion (C.I.V.I.). The aim of this study was. therefore, to assess the antitumor efficacy and toxicity of the combination of bolus VNR and C.I.V.I. IFX as second-line therapy in anthracycline resistant breast cancer patients.
Patients and methods: Forty-two patients with MBC who had already received anthracycline-based chemotherapy were
treated with a regimen consisting of IFX, by C.I.V.I. for 72
hours and bolus VNR. The courses were repeated every three
weeks for a maximum of eight cycles. Four dose intensification
steps were planned: IFX, 1.5 g/m2 on days 1-3 + VNR,
30 mg/m2 on day 1 (six patients); IFX, 2 g/m2 on days 1-3 +
VNR, 25 mg/m2 on day 1 (six patients); IFX, 1.8 mg/m2 on
days 1-3 + VNR, 25 mg/m2 on days 1 and 8 (six patients); IFX,
2 g/m2 on days 1-3 + VNR, 25 mg/m2 on days 1 and 8 (24
patients). Sodium-2-mercaptoethane sulfonate (mesna) was
associated with IFX at an infusion ratio of 1:1 and, once the
infusion was completed, per os every four hours for three times.
Results: All of the 42 patients entered were assessable for
toxicity, and 41 of them for response. Neutropenia was the
most frequently-occurring toxicity, but only five patients at the
highest dose level (11.9%) presented grade 4, and none of those
at the first three steps. Other significant toxic effects were mild
(only grade I-II). The median relative dose intensity was 95%
at the highest dose level and all of the treatments were administered on an out-patient basis. The overall response rate was 36.5% with a CR rate of 4.8% (two of 41 patients, all at the
highest dose level) and a PR rate of 31.7% (13 of 41 patients).
The median response duration was 7.0 months (range 2-13
months).
Conclusions: The present phase I-II study shows that the
IFX and VNR combination is an active and well-tolerated
treatment in MBC and provides an alternative to taxanes for
patients previously treated with anthracyclines
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Author, publisher and bookseller : a tripartite synergy in Nigerian book industry
No full textThis work is about the roles of Author, Publisher and Bookseller in Book development in
Nigeria. The paper started by delving into the history of Book Publishing in Nigeria after
which it proceeded by defining who an author, a publisher, and a bookseller is and
expatiated on the indispensable roles of these key actors in Nigerian Book Industry and in
the emerging Information Society. Furthermore, the various constraints to book
development were identified while the paper advised on how the Book Industry can be
further promoted in Nigeria. However, the paper concluded and made recommendations
on how the Book sector can help in enhancing scholarship in the country
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