2,009 research outputs found
Impact of selective decontamination of the digestive tract on multiple organ dysfunction syndrome: Systematic review of randomized controlled trials
No full textOBJECTIVE:
We examined the impact of selective decontamination of the digestive tract on multiple organ dysfunction syndrome.
DATA SOURCES:
We searched MEDLINE, EMBASE, the Cochrane Register of Controlled Trials, previous meta-analyses, and meetings proceedings.
STUDY SELECTION:
We included all randomized trials comparing both oropharyngeal and intestinal administration of antibiotics in selective decontamination of the digestive tract with or without a parenteral component, with placebo or standard therapy used in the controls.
DATA EXTRACTION:
Two reviewers independently applied selection criteria, performed quality assessment, and extracted the data. The primary end point was the number of patients with multiple organ dysfunction syndrome developing during intensive care unit stay. Secondary end points were overall mortality and multiple organ dysfunction syndrome-related mortality. Odds ratios were pooled with the random effect model.
DATA SYNTHESIS:
We identified seven randomized trials including 1270 patients. Multiple organ dysfunction syndrome was found in 132 of 637 patients (20.7%) in the selective decontamination of the digestive tract group and in 219 of 633 patients (34.6%) in the control group (odds ratio, 0.50; 95% confidence interval, 0.34-0.74; p < .001). Overall mortality for selective decontamination of the digestive tract vs. control patients was 119 of 637 (18.7%) and 145 of 633 (22.9%), respectively, demonstrating a nonsignificant reduction in the odds of death (odds ratio, 0.82; 95% confidence interval, 0.51-1.32; p = .41). In five studies including 472 patients, multiple organ dysfunction syndrome-related mortality was demonstrated in 31 of 239 (13%) patients in selective decontamination of the digestive tract group and 37 of 233 (15.9%) in the controls (odds ratio, 0.84; 95% confidence interval, 0.48-1.41; p = .54).
CONCLUSIONS:
Selective decontamination of the digestive tract reduces the number of patients with multiple organ dysfunction syndrome. Mortality was not significantly reduced, probably because of the small sample size
SDD, SOD, or oropharyngeal chlorhexidine to prevent pneumonia and to reduce mortality in ventilated patients: which manoeuvre is evidence-based?
No full textElastic-DF: Scaling Performance of DNN Inference in FPGA Clouds through Automatic Partitioning
No full textCustomized compute acceleration in the datacenter is key to the wider roll-out of applications based on deep neural network (DNN) inference. In this article, we investigate how to maximize the performance and scalability of field-programmable gate array (FPGA)-based pipeline dataflow DNN inference accelerators (DFAs) automatically on computing infrastructures consisting of multi-die, network-connected FPGAs. We present Elastic-DF, a novel resource partitioning tool and associated FPGA runtime infrastructure that integrates with the DNN compiler FINN. Elastic-DF allocates FPGA resources to DNN layers and layers to individual FPGA dies to maximize the total performance of the multi-FPGA system. In the resulting Elastic-DF mapping, the accelerator may be instantiated multiple times, and each instance may be segmented across multiple FPGAs transparently, whereby the segments communicate peer-to-peer through 100 Gbps Ethernet FPGA infrastructure, without host involvement. When applied to ResNet-50, Elastic-DF provides a 44% latency decrease on Alveo U280. For MobileNetV1 on Alveo U200 and U280, Elastic-DF enables a 78% throughput increase, eliminating the performance difference between these cards and the larger Alveo U250. Elastic-DF also increases operating frequency in all our experiments, on average by over 20%. Elastic-DF therefore increases performance portability between different sizes of FPGA and increases the critical throughput per cost metric of datacenter inference. Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Computer Engineerin
Hydrodynamical turbulence by fractal fourier decimation
No full textWe present a systematic numerical investigation of high-resolution 3D isotropic and homogeneous turbulence resolved on a decimated set of Fourier modes. Fractal decimation acts to decrease the effective dimensionality of the flow by allowing triadic interactions only in a set of Fourier modes N(k) proportional to k^DF for large k. While keeping the symmetries of the original 3D Navier-Stokes equations unchanged, a dramatic change in small-scale statistics is detected at decreasing the fractal dimension DF . Already at fractal dimension DF = 2.8, a global self-similar behaviour is observed in the inertial range of scales, the consequence of such transition are the restoration of the scaling symmetry and vorticity distribution that becomes close to Gaussian. We relate the results to the different roles of local vs non-local interactions in the energy transfer range
'Response by the author, Daniel F. Vukovich.'
No full textResponse by the author (Vukovich) to a review of Illiberal China (my 2019 monograph
DF AND HF LASER SPECTRA
No full textW. B. Roh and K. Narahari Rao, J. Mol. Spectrosc. 49, 317 (1974).""Author Institution: Department of Physics, The Ohio State University; Department of Electrical Engineering, The Ohio State UniversityA pulsed laser was used as a source to study DF and HF infrared laser spectra with a grating spectrometer. The rotational structure observed for the 1-0, 2-1, and 3-2 bands of DF, and the 1-0 and 2-1 bands of HF has been measured by following a procedure similar to that used for the CO laser Molecular constants derived by combining these laser measurements with other available data will be presented
OPTOACOUSTIC MEASUREMENT OF DF LASER ABSORPTION BY METHANE
No full textAuthor Institution:An optoacoustic system has been constructed for measurement of absorption of DF laser radiation. Absorption by methane in Argon and Nitrogen has been measured at 15 DF laser lines in the 3.6 – 4.0 region. Construction and calibration of the spectrophone will be discussed
REFLECTION OF DIFFERENTIAL PULMONARY PERFUSION IN POLYTRAUMA PATIENTS ON DIFFERENTIAL LUNG VENTILATION (DLV) - A COMPARISON OF 2 CO2-DERIVED METHODS
No full text
REFLECTION OF DIFFERENTIAL PULMONARY PERFUSION IN POLYTRAUMA PATIENTS ON DIFFERENTIAL LUNG VENTILATION (DLV) - A COMPARISON OF 2 CO2-DERIVED METHODS
No full text- …
