128 research outputs found
Essential Oils: Antifungal activity and study methods
Essential oils (EOs) are natural, volatile compounds extracted from plants, known for their diverse biological properties, including potent antifungal activity. This review explores the antifungal mechanisms of EOs, their efficacy against human and plant fungal pathogens, and their applications in medicine, agriculture and food preservation. EOs disrupt fungal cell membranes, inhibit ergosterol biosynthesis, induce oxidative stress and interfere with mitochondrial function and enzymatic pathways, leading to fungal cell death. Their broad-spectrum activity makes them promising alternatives to conventional antifungals, particularly in the face of rising antifungal resistance. Synergistic effects with conventional drugs, such as azoles and polyenes, further enhance their therapeutic potential. However, challenges such as variability in composition, stability, sensory impact and regulatory hurdles limit their widespread adoption. Advanced delivery systems, including nano-encapsulation and emulsification, are being explored to improve EO stability and efficacy. In agriculture, EOs show promise as biocontrol agents against crop pathogens, while in food preservation, they inhibit spoilage fungi and extend shelf life. Future research should focus on optimizing EO formulations, conducting in vivo and clinical studies, and developing regulatory frameworks to facilitate their integration into mainstream applications. By addressing these challenges, EOs can emerge as safe, sustainable and effective antifungal agents, offering innovative solutions across multiple industries.
Keywords: Antifungal activities, essential oils, study method
Relationship between Nurses' Emotional Intelligence and Their Organizational Citizenship Behaviors
Abstract: Emotional Intelligence (EI) has been related to a number of positive work outcomes including organizational citizenship behaviors (OCBs). It seems that organizational behavior of each nurse is strongly influenced by EI. Aim: To determine the relationship between nurses’ EI and their organizational citizenship behaviors. Methods: A descriptive, correlational research design was utilized in all inpatient medical, surgical and critical care units at Kafr El-Dawar General hospital, El-Beheira, Egypt, for all staff nurses who will be available at the time of data collection .Tools: two tools were used: Tool Ι: Wong and Law EI Scale (WLEIS) and a demographic characteristics data sheet; Tool Π: Organizational Citizenship Behavior (OCB) Scale. Results: Staff nurses have moderate mean percent score of total EI and have high mean percent score of total OCB. Also, there are positive highly significant relationships between total EI and its dimensions and total OCB and its dimensions. Conclusion: there was highly statistically positive relationship between total EI of the nurses and their organizational citizenship behaviors at Kafr El-Dawar General hospital. Recommendations: Study the impact of managers’ leadership style on nursing staff perception of OCB.
Keywords: Emotional Intelligence, Organizational Citizenship Behavior, WLIES.
Title: Relationship between Nurses' Emotional Intelligence and Their Organizational Citizenship Behaviors
Author: Nahed Samir kozmel, Reem Mabrouk Abd El Rahman, Wafaa Hassan Mostafa
International Journal of Novel Research in Healthcare and Nursing
ISSN 2394-7330
Vol. 10, Issue 3, September 2023 - December 2023
Page No: 14-27
Novelty Journals
Website: www.noveltyjournals.com
Published Date: 06-September-2023
DOI: https://doi.org/10.5281/zenodo.8321297
Paper Download Link (Source)
https://www.noveltyjournals.com/upload/paper/Relationship%20between%20Nurses-06092023-2.pdfInternational Journal of Novel Research in Healthcare and Nursing, ISSN 2394-7330, Novelty Journals, Website: www.noveltyjournals.co
Unsupervised multiblock data analysis: A unified approach and extensions: Unsupervised multiblock data analysis: A unified approach and extensions
ISI Document Delivery No.: JQ2BB Times Cited: 0 Cited Reference Count: 37 Managmana, Essomanda Tchandao Cariou, Veronique Vigneau, Evelyne Kakai, Romain Lucas Glele Qannari, El Mostafa Glele Kakai, Romain/0000-0002-6965-4331 France overseas cultural and cooperation network of the Embassy of France in Togo; African Excellence Center in Mathematical Sciences and Applications of the University of Abomey-Calavi (Benin) The first author is very grateful to France overseas cultural and cooperation network of the Embassy of France in Togo and the African Excellence Center in Mathematical Sciences and Applications of the University of Abomey-Calavi (Benin) for their financial support. 0 3 Elsevier Amsterdam 1873-3239International audienceFor the analysis of multiblock data, a unified approach of several strategies such as Generalized Canonical Correlation Analysis (GCCA), Multiblock Principal Components Analysis (MB-PCA), Hierarchical Principal Components Analysis (H-PCA) and ComDim is outlined. These methods are based on the determination of global and block components. The unified approach postulates, on the one hand, two link functions that relate the block components to their associated global components and, on the other hand, two summing up expressions to compute the global components from their associated block components. Not only several well-known methods are retrieved but we also introduce a variant of GCCA. More generally, we hint to other possibilities of extensions thus emphasizing the fact that the unified approach, besides being simple, is versatile. We also show how this approach of analysis although basically unsupervised could be adapted to yield a supervised method to be used for a prediction purpose. Illustrations on the basis of simulated and real case studies are discussed
Alternative control of helminthosporium leaf spot on wheat using essential oils of Origanum compactum and Thymus satureioides
The production of cereals in Morocco has experienced fluctuations due to various factors, including cryptogamic diseases. The control of these diseases still relies heavily on chemical products that harm the environment. The objective of this study, was to test an alternative method that improves yield and is environmentally friendly in controlling helminthosporium leaf spot disease caused by Bipolaris sorokiniana, using essential oils extracted from medicinal plants. The effect of two essential oils, Origanum compactum and Thymus satureioides, was tested against helminthosporium leaf spot on four varieties of durum wheat (Triticum durum) and common wheat (Triticum aestivum). These two essential oils were applied to the aerial part at a concentration of 0.31 µl/ml for Origanum compactum essential oil and 1.25 µl/ml for Thymus satureioides essential oil. The different parameters evaluated included the types of infection, the greenness rate on the top two leaves at the flowering stage, grain weight, the number of grains per spike, and the weight of a thousand grains. The results showed that both essential oils significantly reduced disease severity by 48% and increased grain yield by an average of 25% across all varieties used. Thymus satureioides was found to be more effective than Origanum compactum, reducing the infection rate by 52% and improving productivity by 50%. These results indicate that the control of this disease can be achieved without the use of synthetic chemical products.
Keywords: Helminthosporium leaf spot, Wheat, Bipolaris sorokiniana, Alternative control, Essential oils, Origanum compactum, Thymus satureioide
Nurses' Perceptions of Health Care Learning Organizational Culture and Their Readiness for Change
Abstract: Healthcare organizations aspire to improve safety and quality in a changing environment, learning organizations' practices can help to reinforce existing skills and knowledge and provide opportunities to find better ways of working. Aim: examine the relationship between nurses' perceptions of health care learning organizational culture and their readiness for change at Kafr El-Dawar General hospital. Study design: A descriptive, correlational research design was used in this study. Setting: This study was carried out in all intensive and critical care units; and inpatient units (medical and surgical) at Kafr El-Dawar General hospital (N=22). with bed capacity (N=278). Subject: All staff nurses, who are working in the previously mentioned settings and who were available at the time of data collection and with at least one year of experience, were included in the study (N=270).Tool Ӏ: Dimensions of Learning Organization Questionnaire (DLOQ). Tool ӀӀ: Attitudes Toward Change Survey (ATCS). Results: The finding of this study revealed that the vast majority of staff nurses had high level of learning organizational culture and high level of readiness for change. Conclusion: The present study shows that there is positive statistical significant relationship between learning organizational culture and readiness for change. Moreover, there are positive high statistical significant relationship between learning organizational culture and all it's dimensions; and between readiness for change and all its dimensions. Recommendations: Investigate how learning organizational culture can be effectively connected in practice to other basic concepts, such as job satisfaction, job performance or organizational commitment.
Keywords: Learning organizational culture, Readiness for change, and Learning organization.
Title: Nurses' Perceptions of Health Care Learning Organizational Culture and Their Readiness for Change
Author: Lobna Abd Elaziz Saad Abd Elaziz, Reem Mabrouk Abd El Rahman, Wafaa Hassan Mostafa
International Journal of Novel Research in Healthcare and Nursing
ISSN 2394-7330
Vol. 10, Issue 3, September 2023 - December 2023
Page No: 1-13
Novelty Journals
Website: www.noveltyjournals.com
Published Date: 06-September-2023
DOI: https://doi.org/10.5281/zenodo.8321320
Paper Download Link (Source)
https://www.noveltyjournals.com/upload/paper/Nurses'%20Perceptions%20of%20Health%20Care%20Learning-06092023-1.pdfInternational Journal of Novel Research in Healthcare and Nursing, ISSN 2394-7330, Novelty Journals, Website: www.noveltyjournals.co
Protective effect of arabic gum against cardiotoxicity induced by doxorubicin in mice: A possible mechanism of protection
Title: Protective effect of arabic gum against cardiotoxicity induced by doxorubicin in mice: A possible mechanism of protection
Author(s): Abd-Allah, ARA, Al-Majed, AA, Mostafa, AM, Al-Shabanah, OA, El Din, AG, Nagi, MN
Source: JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY Volume: 16 Issue: 5 Pages: 254-259 Published: 2002
Department: Pharmacology and Toxicology
Abstract: Arabic gum (AG) is a naturally occurring compound that has been proposed to posses potent antioxidant activity. In this study, the possible effects whereby AG could protect against cardiotoxicity induced by doxorubicin (DOX) in mice were carried out. Administration of single dose of DOX (15 mg/kg, i.p.) induced cardiotoxicity 72 h, manifested biochemically by a significant elevation of serum creatine kinase (CK) (EC 2.7.3.2). In addition, cardiotoxicity was further confirmed by the significant increase in lipid peroxides measured as malondialdehyde (MDA). Administration of AG (25 g/kg) orally for 5 days before and 72 h after DOX injection produced a significant protection against cardiotoxicity induced by DOX. This was evidenced by significant reductions in serum CK and cardiac lipid peroxides. The effect of AG was examined on the superoxide anion radical generated by enzymatic and nonenzymatic methods. The results indicate that AG is a potent superoxide scavenger. The superoxide scavenging effect of AG may explain, at least in part, the protective effect of AG against cardiotoxicity induced by DOX. (C) 2002 Wiley Periodicals, Inc
Diastolic dysfunction and pulmonary hypertension in sickle cell anemia: Is there a role for L-carnitine treatment?
Clinical manifestations of cardiovascular abnormalities in patients with sickle cell (SC) anemia are well documented. Many variables were assessed in our study before and after administration of L-carnitine to randomly selected 37 SC disease (SCD) children for a period of 6 months. Variables such as weight, height, serum ferritin levels, units of blood transfused and the number of veno-occlusive crises all showed significant improvement after the 6 months of therapy with L-carnitine. Our study also showed that cardiac diastolic function and pulmonary hypertention are common in pediatric SCD patients. These two disorders showed some improvement after L-carnitine administration. Therefore, L-carnitine deserves a rigorous large-scale randomized clinical trial to evaluate its potential benefits as treatment for SCD patients with cardiac complications. Copyright © 2006 S. Karger AG.APPLETON CP, 1993, J AM COLL CARDIOL, V22, P1972; ARDUINI A, 1995, CARNITINE SYSTEM NEW, P169; ATWEH GF, 1996, BLOOD S, V88, P652; BAHL VK, 1992, AM HEART J, V124, P1516, DOI 10.1016-0002-8703(92)90066-5; BALFOUR IC, 1984, AM HEART J, V108, P345, DOI 10.1016-0002-8703(84)90623-9; Batra AS, 2002, AM J HEMATOL, V70, P306, DOI 10.1002-ajh.10154; BENNET MJ, 1992, L CARNITINE ITS ROLE, P187; Calvani M, 2004, ANN NY ACAD SCI, V1033, P52, DOI 10.1196-annals.1320.005; Cipolotti R, 2001, J TROP PEDIATRICS, V47, P73, DOI 10.1093-tropej-47.2.73; COLLINS FS, 1982, AM J MED, V73, P814, DOI 10.1016-0002-9343(82)90763-X; COURTOIS M, 1988, CIRCULATION, V78, P661; COVITZ W, 1995, CHEST, V108, P1214, DOI 10.1378-chest.108.5.1214; DONATELLI A, 1987, CURR THER RES, V6, P620; Eidem BW, 2004, J AM SOC ECHOCARDIOG, V17, P212, DOI 10.1067-j.echo.2003.12.005; El-Beshlawy A, 2004, ACTA HAEMATOL-BASEL, V111, P143, DOI 10.1159-000076522; ESTRADE G, 1989, ARCH MAL COEUR VAISS, V82, P1975; Faller Douglas V., 1994, P235; FERRARI R, 1995, CARNITINE SYSTEM NEW, P323; FLORENZANO F, 1984, AM J CARDIOL, V54, P638, DOI 10.1016-0002-9149(84)90264-9; Gladwin MT, 2004, NEW ENGL J MED, V350, P886, DOI 10.1056-NEJMoa035477; Haque AK, 2002, HUM PATHOL, V33, P1037, DOI 10.1053-hupa.2002.128059; ILICETO S, 1995, J AM COLL CARDIOL, V26, P380, DOI 10.1016-0735-1097(95)80010-E; Kane A, 2001, ARCH PEDIATRIE, V8, P707, DOI 10.1016-S0929-693X(00)00302-X; KITABATAKE A, 1983, CIRCULATION, V68, P302; KOUTTAB N, 1993, MED INFLAM, V11, P525; LESTER LA, 1990, CHEST, V98, P1169, DOI 10.1378-chest.98.5.1169; LEWIS JF, 1991, J AM COLL CARDIOL, V17, P1473; MASINDET S, 1993, 18 ANN M NAT SICKL C, pA81; MIRSKY I, 1984, CIRCULATION, V69, P836; MOTTERLINI R, 1992, MOL CELL BIOCHEM, V116, P139, DOI 10.1007-BF01270581; Oh JK, 1997, J AM SOC ECHOCARDIOG, V10, P246, DOI 10.1016-S0894-7317(97)70062-2; Pons R, 1995, J Child Neurol, V10 Suppl 2, pS8; POWARS D, 1988, MEDICINE, V67, P66; Shah P M, 1992, Curr Probl Cardiol, V17, P781; Shankar Sudha S, 2004, Ann N Y Acad Sci, V1033, P189, DOI 10.1196-annals.1320.018; SIMMONS BE, 1988, ARCH INTERN MED, V148, P1526, DOI 10.1001-archinte.148.7.1526; SIMONSON JS, 1988, J AM COLL CARDIOL, V11, P557; STODDARD MF, 1989, J AM COLL CARDIOL, V13, P327; SUTTON LL, 1994, AM J CARDIOL, V74, P626, DOI 10.1016-0002-9149(94)90760-9; TEIN I, 1990, PEDIATR RES, V28, P247, DOI 10.1203-00006450-199009000-00020; Tsagris V, 2005, EUR J PEDIATR, V164, P131, DOI 10.1007-s00431-004-1590-y; Vanella A, 2000, CELL BIOL TOXICOL, V16, P99, DOI 10.1023-A:1007638025856; Vasan RS, 2000, CIRCULATION, V101, P2118; VEILLE JC, 1994, AM J OBSTET GYNECOL, V170, P10769
Plasmonic field effects of silver nanoparticle monolayers on poly(phenylene ethynylene) fluorescent polymers of different chain length
The literature on nanomaterials has been flooded with new shapes, sizes, and compositions of nanostructures. The process of developing and characterizing these particles has been broadly accomplished and many interesting and promising properties have been revealed for application in current and developing technologies. In particular, the phenomenon of surface plasmon resonance seen in metallic gold and silver nanoparticles has drawn substantial interest. It has been established that the electromagnetic fields surrounding plasmonic particle surfaces can influence the properties of nearby systems, causing them to experience effects such as enhanced absorption and emission of light or drastically increased conductivity. For this reason, plasmonic nanoparticles are being applied to an endless number of applications for new materials.
This thesis investigated the effects of silver nanocube (AgNC) arrays on the photophysical properties of poly(paraphenyleneethynylene) (PPE) fluorescent polymers, a particularly relevant material to the applications of organic-electronics. AgNCs were selected because of their particularly strong plasmonic field, which is enhanced at the sharp features of the cubes. The PPE polymer is an exceptionally fluorescent conjugated polymer that often serves as a building block for polymer-based sensing applications. By monitoring the absorption and emission of the PPE polymer, a better understanding of plasmonic effects on this polymer system was obtained. Compression of the monolayer of AgNCs on the surface of a Langmuir-Blodgett trough can be used for control of interparticle distance and, thus, the plasmon field intensity felt by an adsorbed layer of PPE polymer.
In the Chapter 4, PPE (n = 15) emission was monitored as a function of the AgNC plasmonic field. A two-photon process was found to explain the unusual increase then decrease of the fluorescence intensity. This observation was attributed to exciton-exciton annihilation processes within the polymer. The annihilation process is initiated by large enhancements of the polymer absorption rate when plasmonic fields are at their highest (when the AgNCs are compressed to short interparticle distances).
In chapter 5, the optical properties of PPE polymers as a function of their chain length and the AgNC density were examined. A simple study was conducted to consider the conformational/geometrical effects on PPE that were caused by the deposition of PPE onto the AgNC topography. In this study, the structure of the absorption and emission profiles were evaluated and used as evidence of polymer interchain interactions, planarization, and even the potential generation of oligomeric species through breaking of conjugation.
Fundamental interactions between materials must be evaluated and optimized prior to their use in devices. This thesis serves to shed a little bit of light on the interaction of a well-defined plasmonic particle with a conjugated polymer. The Langmuir-Blodgett technique serves as a critical tool in applying these colloidally produced nanoparticles to 2D arrays in practical applications. The observation of exciton-exciton annihilation at low-energy excitation is an entirely new phenomenon that was initiated by the plasmonic properties of metal nanoparticles. It is the hope of the author that the results contained herein can aide in the use of plasmonic nanoparticles in future devices.M.S
Location-based analysis of car-following behavior during braking using naturalistic driving data
This study investigates the car-following behavior during braking at intersections and segments. Car-following events were extracted from a naturalistic driving dataset, mapped using ArcGIS, and analyzed to differentiate between the intersection- and segment-related events. The intersection-related events were identified according to an intersection influence area, which was estimated based on the stopping sight distance and the speed limit. Five behavioral measures were quantified based on exploring the Probability Density Functions (PDF) for intersection- and segment-related events. The results showed that there were significant differences between the PDFs of the measures for both cases. Moreover, it was indicated that drivers tend to be more aggressive at intersections when compared to segments. Thus, it is crucial to consider the driver’s location when investigating driver behavior. The quantified behavioral measures are a rich data source that can be used for car-following microscopic modeling, surrogate safety analysis, and driver assistance systems development.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author
Sustaining the population growth of desert settlements, case study: North Sinai, Egypt
Egypt faces ongoing problems in its population distribution. While heavily populated areas of the
Nile Valley continue to attract migrants, depopulated areas remain largely empty. In North Sinai, in spite
of governmental support represented in new infrastructure and many urban and investment projects, there
exists a tremendous under- population problem. In the meantime the urban centres of Egypt are suffering
worsening social, economic, infrastructural and environmental problems exacerbated by overpopulation.
This thesis addresses the concept of sustaining population growth of desert settlements. It argues
that the socio-economic needs of desert settlements are to a large part overlooked, thus contributing to
their failure to attract and retain large numbers of people. Discussion of this subject is structured into
three parts, followed by the conclusion and recommendations.
Part One uses extensive literature references to give a comprehensive background to the different
features of desert settlements and their social, economic and environmental dimensions. Part Two covers
the theoretical approach of sustaining the population growth of desert settlements, especially in peripheral
areas. This part ends with a comparative analysis between three desert development experiences; in
Egypt, the USA and Israel. These first two parts are targeted to address the indicators of sustaining
population growth. These investigations into the subject area support a view that it is not sufficient for
governments only to use economic, employment and infrastructural means to attract people to desert
settlements. These do not tackle the problem of public attitudes towards living in remote communities,
nor do they provide settlements that are adaptive to the desert environment, which would invite settlers to
remain and bring up their families there. These insights construct the analytical background to the field
study in Part Three, which outlines the research techniques and the case study, field survey and
questionnaire conducted with the assistance of residents of five chosen desert settlements in North Sinai.
This analysis examines the attitudes among `local' and `new comer' households looking at their
residential mobility, the relocation process, and the consequences of the community and prospects for the
future.
The findings lead to the conclusion that much of the deviation from achieving national and
regional population dispersal policies can be explained through studying the socio-economic and
socio-cultural dimensions of desert settlements. They highlight significant differences in values, motivations
and interests of both `local' and `newcomer' households and explain that these forces should have a major
influence in formulating and implementing effective population redistribution policies.
Although the research limits itself to the context of the desert environment, the author suggest that
its findings may offer valuable insights to other parts of the world, where national policies are seeking to
counter the global problems of rural -urban migration
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