685 research outputs found

    First variation formula in Wasserstein spaces over compact Alexandrov spaces

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    We extend results proved by the second author (Amer. J. Math., 2009) for nonnegatively curved Alexandrov spaces to general compact Alexandrov spaces X with curvature bounded below. The gradient flow of a geodesically convex functional on the quadratic Wasserstein space (P(X),W_2) satisfies the evolution variational inequality. Moreover, the gradient flow enjoys uniqueness and contractivity. These results are obtained by proving a first variation formula for the Wasserstein distance. © Canadian Mathematical Society 2011

    Abundant nucleostemin expression supports the undifferentiated properties of germ cell tumors

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    博士論文要旨Abstract 要約Outline 以下に掲載:The American Journal of Pathology. 183(2) pp.592-603 2013. ELSEVIER. 共著者:Noriyuki Uema, Takako Ooshio, Kenichi Harada, Masako Naito, Kazuhito Naka, Takayuki Hoshii, Yuko Tadokoro, Kumiko Ohta, Mohamed A.E. Ali, Miyuki Katano, Tomoyoshi Soga,Yasuni Nakanuma, Akihiko Okuda,and Atsushi Hira

    Association of a murine leukaemia stem cell gene signature based on nucleostemin promoter activity with prognosis of acute myeloid leukaemia in patients

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    金沢大学博士(医学)博士論文本文Full 以下に掲載:Biochemical and Biophysical Research Communications 450(1) pp.837-843 2014. Elsevier Inc. 共著者:Mohamed A.E. Ali, Kazuhito Naka, Akiyo Yoshida, Kyoko Fuse, Atsuo Kasada, Takayuki Hoshii, Yuko Tadokoro, Masaya Ueno, Kumiko Ohta, Masahiko Kobayashi, Chiaki Takahashi, Atsushi Hiraodoctoral thesi

    Association of a murine leukaemia stem cell gene signature based on nucleostemin promoter activity with prognosis of acute myeloid leukaemia in patients

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    博士論文本文Full 以下に掲載:Biochemical and Biophysical Research Communications 450(1) pp.837-843 2014. Elsevier Inc. 共著者:Mohamed A.E. Ali, Kazuhito Naka, Akiyo Yoshida, Kyoko Fuse, Atsuo Kasada, Takayuki Hoshii, Yuko Tadokoro, Masaya Ueno, Kumiko Ohta, Masahiko Kobayashi, Chiaki Takahashi, Atsushi Hira

    Strong therapeutic potential of γ-secretase inhibitor MRK003 for CD44-high and CD133-low glioblastoma initiating cells

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    博士論文要旨Abstract 要約Outline 以下に掲載:Journal of Neuro-Oncology 121(2) pp.239-250 2015. Springer. 共著者:Shingo Tanaka, Mitsutoshi Nakada, Daisuke Yamada, Ichiro Nakano, Tomoki Todo, Yasushi Ino, Takayuki Hoshii, Yuko Tadokoro, Kumiko Ohta, Mohamed A.E. Ali, Yutaka Hayashi, Jun-ichiro Hamada, Atsushi Hira

    Minimum search to establish worst-case guarantees in coalition structure generation

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    Coalition formation is a fundamental research topic in multi-agent systems. In this context, while it is desirable to generate a coalition structure that maximizes the sum of the values of the coalitions, the space of possible solutions is often too large to allow exhaustive search. Thus, a fundamental open question in this area is the following: Can we search through only a subset of coalition structures, and be guaranteed to find a solution that is within a desirable bound (beta) from optimum? If so, what is the minimum such subset? To date, the above question has only been partially answered by Sandholm et al. in their seminal work on anytime coalition structure generation [Sandholm et al., 1999]. More specifically, they identified minimum subsets to be searched for two particular bounds: β = n and β = [n/2]. Nevertheless, the question remained open for other values of β. In this paper, we provide the complete answer to this question

    Abundant nucleostemin expression supports the undifferentiated properties of germ cell tumors

    No full text
    金沢大学博士(医学)博士論文要旨Abstract 要約Outline 以下に掲載:The American Journal of Pathology. 183(2) pp.592-603 2013. ELSEVIER. 共著者:Noriyuki Uema, Takako Ooshio, Kenichi Harada, Masako Naito, Kazuhito Naka, Takayuki Hoshii, Yuko Tadokoro, Kumiko Ohta, Mohamed A.E. Ali, Miyuki Katano, Tomoyoshi Soga,Yasuni Nakanuma, Akihiko Okuda,and Atsushi Hiraodoctoral thesi

    Alvinocaris longirostris Kikuchi and Ohta 1995

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    Alvinocaris longirostris Kikuchi and Ohta, 1995 (Figs. 2–5) Alvinocaris longirostris Kikuchi and Ohta, 1995: 772, figs. 1–7; Komai and Segonzac, 2005: 1148, figs. 19, 20, 29. Material examined. 1 male (cl 12.35 mm), cold seep, Jiaolong Cold Seep I, ridge between continental shelf and slope, off Guangdong Province, China, southwest to Taiwan Island, northeastern South China Sea, 22 ° 6.948 ’N, 119 ° 17.116 ’E, 1138 m depth, collected with small net held by manipulator of “Jiaolong” submersible, collectors: Jian-wen Qiu and Xinzheng Li, 19 June 2013. Description of specimen from the South China Sea. Large Alvinocaris shrimp. Rostrum directed forward, very slightly curved dorsally, 0.50 of carapace length, distal part damaged, remaining part almost reaching to distal margin of second segment of antennular peduncle; dorsal margin armed with 11 + teeth, including 7 + teeth on rostrum proper and 4 relatively strong teeth on carapace posteriror to orbital margin, posteriormost tooth arising at anterior 0.39 of carapace length; ventral margin armed with 2 + small subdistal teeth. Carapace width 0.66 of length; postrostral median ridge moderately high, extending to 0.80 of carapace length, dorsal angle about 157 °; pterygostomial tooth weakly produced anteriorly, shorter and more robust than antennal tooth, exceeding antennal tooth; post-antennal groove distinct; branchial region not particularly inflated. Third abdominal pleuron unarmed. Fourth abdominal pleuron with small posteroventral tooth and 1 very small additional tooth on posterior margin and very 1 (right) or 2 (left) small additional teeth on ventral margin. Fifth abdominal pleuron armed with strong posteroventral tooth and 1 (left) or 3 (right) additional teeth on posterior margin. Sixth abdominal somite 0.43 times as long as carapace, 1.25 times longer than height, pleuron with strong posterolateral and posteroventral tooth. Telson 1.56 times as long as sixth abdominal somite, not reaching posterior margin of uropodal endopod, 2.33 times as long as anterior width and 4.30 times as long as posterior width; armed with 6 (right) or 8 (left) dorsolateral spines; posterior margin evenly slightly convex, armed with 1 (right) or 2 (left) spines similar to dorsolateral ones at lateral corners and 10 plumose setae all longer than mesial pair of lateral spines. Eyes small, stalk short, cornea indistinct. Antennular peduncle stout, stylocerite exceeding mid-length of second segment, distolateral tooth of first segment extending to proximal 0.40 of second segment; second segment 1.68 times longer than wide, distomesial tooth acute. Antennal scale 0.45 times as long as carapace, 1.82 times longer than wide; lateral margin straight, slightly converging against dorsal median ridge; distolateral tooth directed forward, falling short of broadly rounded distal margin of blade. First and second pereopods symmetrical. First pereopod robust; greatest height of palm 1.18 times as long as length of palm; fingers strongly curved medially, dactylus 2.35 times as long as length of palm, carpus and merus unarmed. Second pereopod very slender, merus unarmed. Third pereopod moderately slender; dactylus 0.19 times as long as propodus, with accessory spinules notably increasing in size distally; carpus 0.72 times as long as propodus; merus 1.17 times as long as propodus, 5.92 times as long as greatest height, with a strong spine at middle ventral margin. Fourth and fifth pereopods similar to third, with merus unarmed. Measurements. Carapace length= 12.35 mm; carapace width= 7.86 mm; rostrum length= 6.12 mm; telson length= 8.21 mm. Colouration. Body entirely semi-transparent ivory-white, eyes white (Figs. 2, 3). Remarks. The present male specimen agrees well with the original (Kikuchi and Ohta, 1995) and Komai and Segonzac’s (2005) descriptions and illustrations. The similarities of nucleotide sequences of the genes 16 S RNA and COI from the present specimen are more than 99 % comparing with those provided by G. Tokuda, R. P. Kumara and H. Yamasaki [genbank number: AB 821296.1 (mitochondrial DNA complete genome), fig. 4, COI, fig. 5, 16S RNA] and K. H. Chu and T.-Y. Chan [genbank number: GQ 131897.1 (16 S RNA)] from specimens from Okinawa Trough, Hatoma Knoll, the type locality. Alvinocaris longirostris was not previously reported from the South China Sea. This record extends the distribution of the species much south into the South China Sea. As Komai and Segonzac (2005) pointed out, this species may be the only one in the family Alvinocarididae that occurs on both hot vents and cold seeps (see Teixeira et al. 2013). This record is the second record of the species from cold seep, after Fujikura et al. (1995) reported it from the Sagami Bay, at similar depth (1120–1220 m) as this record, although the species was first reported from hydrothermal vent. Same as Alvinocaris longirostris Kikuchi and Ohta, 1995, the two key species of the Bathymodiolus platifrons — Shinkaia crosnieri Community from the Jiaolong Cold Seep I, Bathymodiolus platifrons Hashimoto & Okutani, 1994 and Shinkaia crosnieri Baba & Williams, 1998 were also reported from Okinawa Trough in the habitat fluenced by hydrothermal vent. These three species are also the key species in the hydrothermal vent community. Recently, the author visited the Jiaolong Cold Seep I again in April 2014 for field work with the scientific vessel “Kexue” using ROV “Faxian”, more specimens of Alvinocaris longirostris Kikuchi and Ohta, Bathymodiolus platifrons Hashimoto & Okutani, 1994 and Shinkaia crosnieri Baba & Williams, 1998 were collected. The 14 known species of the genus Alvinocaris can be distinguished by the following key with caution as it is designed for identifying adult specimens. The key is modified after Komai & Segonzac’s (2005) key.Published as part of Li, Xinzheng, 2015, Report on two deep-water caridean shrimp species (Crustacea: Decapoda: Caridea: Alvinocarididae, Acanthephyridae) from the northeastern South China Sea, pp. 130-138 in Zootaxa 3911 (1) on pages 132-135, DOI: 10.11646/zootaxa.3911.1.8, http://zenodo.org/record/24050

    Daytime nap controls toddlers' nighttime sleep

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    主査 : 水野雅文 / タイトル : Daytime nap controls toddlers' nighttime sleep / 著者 : Machiko Nakagawa, Hidenobu Ohta, Yuko Nagaoki, Rinshu Shimabukuro, Yoko Asaka, Noriko Takahashi, Takayo Nakazawa, Yousuke Kaneshi, Keita Morioka, Yoshihisa Oishi, Yuriko Azami, Mari Ikeuchi, Mari Takahashi, Michio Hirata, Miwa Ozawa, Kazutoshi Cho, Isao Kusakawa, Hitoshi Yoda / 掲載誌 : Scientific Reports / 巻号・発行年等 : 6:27246, 2016 / 本文ファイル: 出版者

    Daytime nap controls toddlers' nighttime sleep

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    主査 : 水野雅文 / タイトル : Daytime nap controls toddlers' nighttime sleep /著者 : Machiko Nakagawa, Hidenobu Ohta, Yuko Nagaoki, Rinshu Shimabukuro, Yoko Asaka, Noriko Takahashi, Takayo Nakazawa, Yousuke Kaneshi, Keita Morioka, Yoshihisa Oishi, Yuriko Azami, Mari Ikeuchi, Mari Takahashi, Michio Hirata, Miwa Ozawa, Kazutoshi Cho, Isao Kusakawa, Hitoshi Yoda /掲載誌 : Scientific Reports /巻号・発行年等 : 6:27246, 2016
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