3,108 research outputs found
Drift-free single crystalline silicon micromirror with floating field limiting shields
No full textThis paper presents the charging mitigation method at single crystalline silicon micromirror by means of improving the geometry around electrodes. We have now determined that tilt angle drift and stiction are due to the charging effect, and that the effect can be enormously reduced by floating field limiting shields around the electrodes and dielectric geometry. While 0.5 degrees drift was measured at the 83% voltage of the pull-in voltage from the previous micromirror model, the micromirror considering drift-free design showed plusmn0.005 degrees drift at the same percentage voltage of it. At the 97.7% of the pull-in voltage, stiction occurred after about 220 seconds from the previous micromirror model. On the other hand, newly designed micromirror did not show any pull-in effect even at above percentage of it
19.1 A 300MHz-BW, 27-to-38dBm In-Band OIP3 sub-7GHz Receiver for 5G Local Area Base Station Applications
No full textRecently, the so-called sub-6GHz band of the 5G new radio (NR) has been extended to 7.125GHz to address the relentless customer demand for higher data-rate communication. This demands a new design approach for the local area base-station (LA-BS) receivers (RXs) to cover a wide operating frequency range of 0.41 to 7.125GHz. Moreover, for NR bands above 3GHz, the maximum RF bandwidth (BW) is as high as 400MHz, in which a -35dBm modulated in-band (IB) blocker can be present. These impose stringent BW and IB linearity requirements for the baseband amplifiers in the LA-BS receivers. In addition to IB interferences, a -15dBm continuous-wave (CW) out-of-band (OOB) close-in blocker can also be present at 60MHz offset frequency from the passband edges, thus demanding a highly selective RX. Finally, the blocker 1dB compression point (B1textdB) becomes a key parameter for local area co-location applications in which the power of the far-out OOB blocker can be as large as -4dBm.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic
A 4 GHz Continuous-Time ΔΣ ADC With 70dB DR and -74dBFS THD in 125MHz BW
No full textA 4 GHz third-order continuous-time ΔΣ ADC is presented with a loop filter topology that absorbs the pole caused by the input capacitance of its 4-bit quantizer and also compensates for the excess delay caused by the quantizer's latency. The ADC was implemented in 45 nm-LP CMOS and achieves 70 dB DR and -74 dBFS THD in a 125 MHz BW, while dissipating 260 mW from 1.1/1.8 V supply. The ADC occupies 0.9 mm 2 including the modulator, clock circuitry and decimation filter.Accepted Author ManuscriptElectronic Instrumentatio
Estimation of standard liver volume for liver transplantation in the Korean population
No full textThe standard liver volume (LV) of a recipient is estimated in liver transplantation to determine the minimum LV necessary for the recipient. Simple linear formulas of LV estimation were developed for the Japanese and Caucasian populations. The present study examined the applicability of the reported formulas to the Korean population. Liver density (LD) was determined by analyzing 24 healthy livers. Data of liver weight (LW), body weight (BW), body height (BH), body surface area (BSA), and age were obtained from 652 postmortem examination reports (age, 42.4 +/- 16.5 years) showing normal livers. The LV of each subject was estimated by LW/LD and the relationships between LV, BW, BSA, and age were analyzed. LD was 1.04 +/- 0.07 kg/L. LV/BW decreased as age increased in the children but leveled off in the adults; the rate of increase in LV along with BSA in individuals with BSA < 1.2 m(2) appeared less than the corresponding rate in individuals with BSA greater than or equal to 1.2 m(2). The Japanese formula produced underestimates for the Korean population (226.9 +/- 289.4 mL), while the Caucasian formula produced random errors (-30.64 +/- 281.5 mL). A better LV estimation formula was established: LV (mL) = 21.585 x BW (kg)(0.732) x BH (cm)(0.225) (adjusted R-2 = 0.59; SE = 275.8 mL). In conclusion, this study indicates that a nonlinear or piecewise linear model is more desirable than a simple linear model for LV estimation in children and adults, because LV/BW and LV/BSA are not constant with age and BSA.X114749sciescopu
Maternal birth weight and BMI mediate the transgenerational effect of grandmaternal BMI on grandchild’s birth weight
No full textObjectiveThe aims of this study are to examine the potential association between grandmaternal BMI and grandchild’s birth weight (BW) and whether maternal BW and BMI mediate this association.MethodsData of 209 grandmother-mother pairs and 355 grandchildren from the Isle of Wight birth cohort in the UK were analyzed using path analysis.ResultsAn indirect effect of grandmaternal BMI on increasing grandchild’s BW was mediated by maternal BW and BMI at age 18 years (indirect effects: β = 2.3 g/unit increase in grandmaternal BMI via maternal BW and β = 4.4 g via maternal BMI; P = 0.04). These two mediating effects of maternal BW and BMI confounded one another. Grandmaternal smoking during pregnancy had an indirect effect on decreasing grandchild’s BW, dependent on maternal smoking during pregnancy and BW (indirect effects: β = −36.1 g compared with nonsmoking grandmothers via maternal smoking during pregnancy and β = −27.2 g via maternal BW; P = 0.005). Neither direct effect between grandmaternal BMI and grandchild’s BW nor that between grandmaternal smoking during pregnancy and grandchild’s BW was statistically significant.ConclusionsLarger grandmaternal BMI indirectly increased grandchild’s BW via maternal BW and BMI. Grandmaternal smoking during pregnancy indirectly reduced grandchild’s BW via maternal smoking during pregnancy and BW.</p
A 280μW dynamic-zoom ADC with 120dB DR and 118dB SNDR in 1kHz BW
No full textMicro-power ADCs with high linearity and dynamic range (DR) are required in several applications, such as smart sensors, biomedical imaging, and portable instrumentation. Since the signals of interest are then often small (tens of μν) and slow (<1kHz BW), such ADCs should also exhibit low offset and flicker noise. Noise-shaping SAR [1] and incremental ADCs [2] have been proposed for such applications, but their DR is limited to about 100dB. Although the ΔΣ modulator (ΔΣM) proposed in [3] achieves 136dB DR, it is at the expense of high power consumption (12.7mW). The incremental zoom ADC proposed in [4] combines a coarse SAR ADC and a fine ΔΣ ADC to efficiently achieve 119.8dB DR, but is limited to DC signals. The dynamic zoom ADC in [5] solves this problem, but requires external filtering to cope with out-of-band interference. This paper describes an interferer-robust dynamic zoom ADC that consumes 280μW while achieving 120.3dB DR and 118.1dB SNDR in 1kHz BW, resulting in a Schreier FoM of 185.8dB. It also achieves a maximum offset of 30μν and a 1/f corner of 7Hz. These advances are achieved by the combination of dynamic error-correction techniques, an asynchronous SAR ADC and a fully differential inverter-based ΔΣ ADC.Session 14.5 Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic Instrumentation(OLD)Applied Quantum ArchitecturesMicroelectronic
Using bacterial biomarkers to identify early indicators of cystic fibrosis pulmonary exacerbation onset
No full textAcute periods of pulmonary exacerbation are the single most important cause of morbidity in cystic fibrosis patients, and may be associated with a loss of lung function. Intervening prior to the onset of a substantially increased inflammatory response may limit the associated damage to the airways. While a number of biomarker assays based on inflammatory markers have been developed, providing useful and important measures of disease during these periods, such factors are typically only elevated once the process of exacerbation has been initiated. Identifying biomarkers that can predict the onset of pulmonary exacerbation at an early stage would provide an opportunity to intervene before the establishment of a substantial immune response, with major implications for the advancement of cystic fibrosis care. The precise triggers of pulmonary exacerbation remain to be determined; however, the majority of models relate to the activity of microbes present in the patient's lower airways of cystic fibrosis. Advances in diagnostic microbiology now allow for the examination of these complex systems at a level likely to identify factors on which biomarker assays can be based. In this article, we discuss key considerations in the design and testing of assays that could predict pulmonary exacerbations
Apsidal motion elements of three eccentric eclipsing binaries: V397 Cep, V493 Car and BW Aqr
No full textThe apsidal motion analysis of the eccentric eclipsing binaries: V397 Cep, V493 Car and BW Aqr have been presented. The method described by Lacy (1992) [Lacy, C.H S.. 1992. AJ 104, 2213] has been used for the apsidal motion analysis. The apsidal motion periods have been found to be 174.2 +/- 1.4, 277.3 +/- 21.3 and 7195 +/- 174 years for V397 Cep, V493 Car and BW Aqr, respectively. (C) 2009 Elsevier B.V. All rights reserved.Research Foundation of the Canakkale Onsekiz Mart UniversityThe author acknowledges the partial support by Research Foundation of the Canakkale Onsekiz Mart University
Migration of influenza virus-specific polypeptides from cytoplasm to nucleus of infected cells.
No full textAbstract
Previous studies have shown that various influenzavirus polypeptides are associated with the infected cell nucleus. To clarify the pattern of distribution of influenzavirus-specific polypeptides between nucleus and cytoplasm in infected cells and to gain further information concerning functions of influenzavirus replication occurring in the host cell nucleus, we have used high-resolution pulse-labeling experiments and detailed ultrastructural examination of purified preparations of nuclei. In addition to NP and NS1, both P1 and P2 associate preferentially with the nucleus, while P3 and NS2 remain in the cytoplasm. The viral M protein is seen in nuclear fractions only when these fractions are significantly contaminated by plasma membrane. The preferential association of P1 and P2 with nuclei suggests that these proteins, in conjunction with NP and NS1, are involved in specific functions which may include viral transcription, while P3 and NS2 are involved in a distinct role in the cytoplasm.
Author to whom reprint requests should be sent.1
Present address: The Rockefeller University, 1230 York Avenue, New York, N. Y. 10021.
2
Permanent address: Istituto di Microbiologia, Universita Degli Studi di Parma, Italy.
Copyright © 1981 Published by Elsevier Inc.
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"g conti migration nuclear cytoplasmic influenza virus "
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[[alternative]]The effect of KR precision within bandwidth on the learning of a spatial motor task
No full text[[abstract]]The purpose of this study was to investigate the effects of precision of knowledgeof results within bandwidth on learning a spatial motor task and its development of error detection capability. Thirty-two university female students who had no previous golf putting experience served as participants and were randomly assigned to one of following groups:(1)within BWKR group;(2)within BW and error direction of KR group;(3)within BW and error magnitude of KR group; and (4)tranditional BWKR group.Experimental trials for pretest to test the homogeneity of participants, 100practice trials for acquisition, 20 trials for 10-minute immediate retention test,and 20 trials for one-day delay retention test. Other than measuring participants' performance during acquistion and retention phases, on interviewing participants'perception of feedback information was also administered. The error(AE), vaiableerror(VE), and absolute difference between objective performance and subjective estimation(|O-S|). Two-way ANOVA with one factor repeated, Tukey's HSD method and test were used for statistical analysis. Findings were as followings:(1)different percision KR within bandwidth did not affect movement consistency; (2)BWKR in combination of both qualitative KR and qualitative KR was found beneficial for participants' movement accuracy. Both groups which were provided" qualitative KRwithin BW associated with qualitative KR outside BW" produced participants' development of error detection capability. Among it, providing qualitative within BW" had positive effects on participants' development of error detection capability.
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