1,721,988 research outputs found
Huang Yu-Xing : jardin des révolutionnaires
Full text linkVivement colorée, tiraillée entre plusieurs lignes de forces figuratives et abstraites, l'œuvre de Huang Yu-Xing n'est pas sans rappeler l’époque symboliste, comme le souligne Anne Malherbe dans son essai [« Huang Yu-Xing, une obscurité pleine de phosporescences » (pp. 5-7)]. Le lecteur aura plaisir à découvrir ce jeune artiste chinois (né en 1975), dont la peinture Jardin des révolutionnaires (2012) pourrait à elle seule symboliser l’engagement spirituel. Neuf peintures de l'artiste sont ici..
Molecular mechanism of Dang-Shen-Yu-Xing decoction against Mycoplasma bovis pneumonia based on network pharmacology, molecular docking, molecular dynamics simulations and experimental verification
Full text linkMycoplasma bovis pneumonia is a highly contagious respiratory infection caused by Mycoplasma bovis. It is particularly prevalent in calves, posing a significant threat to animal health and leading to substantial economic losses. Dang-Shen-Yu-Xing decoction is often used to treat this condition in veterinary clinics. It exhibits robust anti-inflammatory effects and can alleviate pulmonary fibrosis. However, its mechanism of action remains unclear. Therefore, this study aimed to preliminarily explore the molecular mechanism of Dang-Shen-Yu-Xing decoction for treating mycoplasma pneumonia in calves through a combination of network pharmacology, molecular docking, molecular dynamics simulation methods, and experimental validation. The active components and related targets of Dang-Shen-Yu-Xing decoction were extracted from several public databases. Additionally, complex interactions between drugs and targets were explored through network topology, Gene Ontology, and Kyoto Encyclopedia of Genes and Genomes enrichment analyses. Subsequently, the binding affinity of drug to disease-related targets was verified through molecular docking and molecular dynamics simulation. Finally, the pharmacodynamics were verified via animal experiments. The primary network topology analysis revealed two core targets and 10 key active components of Dang-Shen-Yu-Xing decoction against Mycoplasma bovis pneumonia. Kyoto Encyclopedia of Genes and Genomes enrichment analysis showed that the mechanism of Dang-Shen-Yu-Xing decoction for treating mycoplasma bovis pneumonia involved multiple signaling pathways, with the main pathways including PI3K-Akt and IL17 signaling pathways. Moreover, molecular docking predicted the binding affinity and conformation of the core targets of Dang-Shen-Yu-Xing decoction, IL6, and IL10, with the associated main active ingredients. The results showed a strong binding of the active ingredients to the hub target. Further, molecular docking dynamics simulation revealed three key active components of IL10 induced by Dang-Shen-Yu-Xing decoction against Mycoplasma bovis pneumonia. Finally, animal experiments confirmed Dang-Shen-Yu-Xing decoction pharmacodynamics, suggesting that it holds potential as an alternative therapy for treating mycoplasma bovis pneumonia
Climate talks postponed due to coronavirus pandemic but action must continue
No full textThe Straits Time
Commentary: This new Ministry of Sustainability and Environment looks pretty promising
No full textChannel NewsAsi
The research of the words from ＂Li-Sao＂ by Yu-Xing-Wu 's textual criticism
No full text[[abstract]] 于省吾所撰之《澤螺居楚辭新證》，係以文字、古文物二重證據之考釋方法，對《楚辭》部分詞語進行考證的著述。于氏在疏證《楚辭》方面的著作目前仍未受到關注，因此，筆者希望能透過于氏對《楚辭》詞語的考述，來探討其《楚辭》論證方面的考察。在《澤螺居楚辭新證》書中，于省吾共考證49條詞語，本文以于氏在是書中針對同篇考證最多的〈離騷〉為論述焦點，透過於氏引述及論辨的過程加以分析，對於于氏在《澤螺居楚辭新證．離騷》這14條詞語中所運用的資料與出土文獻等進行整理、製表。首先，筆者先梳理于省吾的生平傳略及其著作概況，再逐步以于氏考釋詞語的方式、其《楚辭》研究的價值及于氏論述中需重新商榷之處，分析于氏的《楚辭》研究。
The research called ＂Ze Lo Ju Chu Ci new residence＂ written by Yu-Xing-Wu, through ancient writing and some antiquities method to verify ＂Chu-Ci＂ some words. But, his research in ＂Chu-Ci＂ did not get attention as famous as his other research. Therefore, I hope through ＂Ze Lo Ju Chu Ci new residence＂ In the book, Yu-Xing-Wu total research 49 words. ＂Li-Sao＂ which is known as Qu-Yuan's autobiography and is the one of famous in ＂Chu-Ci＂, Mr. Yu verified 14 words in this chapter, which is the maximum number of the ＂Ze Lo Ju Chu Ci new residence＂. This article introduce Mr. Yu’s life and his writings , then gradually to his way on the textual research and explanation words , analyzing the value of its ＂Chu-Ci＂ research and question, with his ＂Chu-Ci＂ research
Ren kou xue kan /
No full textPublisher: Guo li Taiwan da xue ren kou yu xing bie yan jiu zhong xin, Description based on: Di 4 qi
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