96,443 research outputs found
Erratum to: Effect of moderate red wine intake on cardiac prognosis after recent acute myocardial infarction of subjects with Type 2 diabetes mellitus (Diabetic Medicine, (2006), 23, 9, (974-981), 10.1111/j.1464-5491.2006.01886.x)
No full textIn an article by Marfella et al, the author name C. Saron is incorrect and should be listed as C. Sardu. Therefore the correct author list is: R. Marfella, F. Cacciapuoti, M. Siniscalchi, F. C. Sasso, F. Marchese, F. Cinone, E. Musacchio, M. A. Marfella, L. Ruggiero, G. Chiorazzo, D. Liberti, G. Chiorazzo, G. F. Nicoletti, C. Sardu, F. D'Andrea, C. Ammendola, M. Verza and L. Coppola.In an article by Marfella et al, the author name C. Saron is incorrect and should be listed as C. Sardu. Therefore the correct author list is: R. Marfella, F. Cacciapuoti, M. Siniscalchi, F. C. Sasso, F. Marchese, F. Cinone, E. Musacchio, M. A. Marfella, L. Ruggiero, G. Chiorazzo, D. Liberti, G. Chiorazzo, G. F. Nicoletti, C. Sardu, F. D'Andrea, C. Ammendola, M. Verza and L. Coppola
A 0.12mm<sup>2</sup> Wien-Bridge Temperature Sensor with 0.1°C (3σ) Inaccuracy from -40°C to 180°C
No full text Resistor-based temperature sensors can achieve much higher resolution and energy efficiency than conventional BJT-based sensors [1], but they typically occupy more area (> 0.25 mm 2 ) and have lower operating temperatures (le 125 {circ} {C}) [2]-[4]. This work describes a 0.12mm 2 resistor-based sensor that uses a Wien-bridge (WB) filter to achieve 0.1 {circ} {C} (3 sigma) inaccuracy from - 40 {circ} {C} to 180 {circ} {C}. Compared to a state-of-the-art WB sensor [4], it occupies 6 × less area and achieves comparable relative accuracy over a 76% wider operating range. Session 10.3 Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic InstrumentationMicroelectronic
F. C. Heim to Horace Kephart, June 12, 1898
No full textIn this letter of June 12, 1898, F. C. Heim writes Horace Kephart to let him know that he is sorry the government is not supporting the independent Sharpshooters. Heim sends 60 cents and asks Kephart to send him a copy of his Infantry tactics so he can prepare and he hopes to see a report on Kephart’s experiment with 30 caliber Winchester in the publication “Shooting and Fishing.”June 12, 1898
Haubstadt, Ind.
Mr. Horace Kephart.
Kind Sir
Your letter
viewed I wish to say that I am
sorry the government sees fit to
“pour cold water” upon those of us,
I say us for I am with you heart
and soul, who are trying to do
that which in my opinion he should
encourage and ought to have done
years ago.
But be of good cheer your movement
will not be lost.
I enclose money order to and of
60 cents; please send me Infantry
tactics. (paper) and mark that
part of the drill that applies to
your organization.
I should not like to come to you
as “green as a gourd” in regard
to military drill.
Hope you will report in S and F.
the result of your experiments
with the 30 cal. Winchester as adopted
by you. Yours
F. C. Hei
Seung Soo You
No full text학위논문(석사)--아주대학교 일반대학원 :분자과학기술학과,2011. 2Surface modification of the biomaterials was widely investigated to improve bio compatibility. In particular, the PEG based hydrogel coating systems were developed due to various advantages of the hydrogels such as high hydrophilicity and lubricity. Heparin has been studied as a bio-active material for surface modification to produce not only bio compatible surface but also anti-coagulant surface. Heparin is the most commonly used anticoagulant reagent in clinical use and heparinization of surfaces which has been shown to be a successful strategy to prevent thrombus formation and to improve blood compatibility of blood-contacting medical devices. However, physical adsorption of hydrogels limits the durability in the long-term exposure in vivo.
In this study, in situ forming heparin and PEG based hydrogels as a coating material was developed to improve blood compatibility of the metal devices and the durability of the hydrogel coating layer on the surface. 316L stainless steel (SS) substrates were simply and rapidly coated with hydrogels via horseradish peroxidase (HRP) enzymatic reaction in presence of hydrogen peroxide (H2O2). After hydrogel coating, durability of the hydrogel coating layer was evaluated. Heparin and PEG based hydrogel coating layer was stable for 7 days. Hydrogel coated surface effectively inhibited the protein adsorption and platelet adhesion. Surface bound heparin has suppressed the coagulation on the hydrogel coated surface by inactivating antithrombin. Our results demonstrated that the in situ forming heparin and PEG based hydrogel has great potential for use as a surface coating materials to improved blood compatibility of the metal surface.I. INTRODUCTION 1
A.Biomaterial-body interaction at biointerface 1
B.Surface modifications for improved biocompatibility 4
1. Hydrogel 5
1) In situ forming hydrogel 6
2) Application of hydrogel 7
2. Heparin 9
1) Structure of heparin 9
2) Medical importance of heparin 12
3) Interaction of heparin with proteins 17
C. Hydrogel coating 21
D. Objectives 22
II. EXPERIMENTS 23
A. Materials 23
B. Synthesis of Tetronic-Tyramine/Dopamine (TTD) conjugates 24
C. Synthesis of NH2-PEG-Tyramine (NH2-PEG-TA) conjugates 26
D. Synthesis of HT and HPT conjugates 29
E. Preparation of heparin and PEG based hydrogel coated Surface 30
1. Mechanical property 30
2. Hydrogel coating 30
3. Coating stability test 31
F. Bloodcompatibility test 34
1. Factor Xa assay 34
2. Protein adsorption 35
3. Platelet adhesion 36
4. Hemolysis test 37
III. RESULTS AND DISCUSSION 38
A. Synthesis and characterizations 38
B. Mechanical strength 42
C. Hydrogel coating stability 44
D. Factor Xa Assay 46
E. In vitro blood compatibility test 48
IV. CONCLUSIONS 55
V. REFERENCES 56
Abstract (in Korean) 64Maste
A CMOS Dual- RC Frequency Reference With ±200-ppm Inaccuracy From -45 °C to 85 °C
No full textThis paper presents a 7-MHz CMOS RC frequency reference. It consists of a frequency-locked loop in which the output frequency of a digitally controlled oscillator (DCO) is locked to the combined phase shifts of two independent RC (Wien bridge) filters, each employing resistors with complementary temperature coefficients. The filters are driven by the DCO's output frequency and the resulting phase shifts are digitized by high-resolution phase-to-digital converters. Their outputs are then combined in the digital domain to realize a temperature-independent frequency error signal. This digitally assisted temperature compensation scheme achieves an inaccuracy of ±200 ppm from -45 °C to 85 °C after a two-point trim. The frequency reference draws 430 μA from a 1.8-V supply, while achieving a supply sensitivity of 0.18%/V and a 330-ppb Allan deviation floor in 3 s of measurement time.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic InstrumentationMicroelectronics(OLD)Applied Quantum Architecture
Viscoelastic Characterisation of High Protein Ice Cream: Predicting Tactile Sensory Properties via Time–Concentration Superposition and Large Amplitude Oscillatory Shear (LAOS) Rheology
No full textIn the present work we report on the exploration of time concentration superposition principle (TCS) and non- linear dynamic rheology (LAOS) as useful instrumental tools for predicting tactile sensory modalities of ice cream at serving temperature ( 14 ◦C). Three common tactile sensory properties of ice cream i.e., resistance to scooping (scoopability), creaminess and gumminess were assessed in high protein formulations differing in their protein to fat ratio (φP/F =0.9 to 4) and protein source (milk protein concentrate (MPC) vs whey protein isolate- sodium caseinate (WPICAS) 1:1 blend). The complex viscosity – angular frequency data obeyed the TCS principle with the calculated shift factors reflecting effectively the compositional profile of ice creams i.e., ac ∝ φP/F 1.16 and φP/F 2.23, bc ∝ φP/F1.27 and φP/F1.75 for MPC and WPICAS fortified systems. LAOS assessment revealed a clear impact of protein type and φP/F on the shearing deformation of ice creams. MPC fortification and decrease in the φP/F enhanced the shear flowing ability of the ice creams. In all cases, the onset of shear stiffening and thickening behaviour was observed at shear stresses below the flow point, which indicates gel-like or colloid glass-like structures. According to partial least squares regression analysis, the TCS parameters (ac and bc), damping factor (tanδ) and the shear strain (γf) and elastic modulus (log Gʹ f) at flow point were determined as the most important parameters predicting tactile sensory modalities on large deformation (spooning) such as scoopability, creaminess and gumminess
Mitomycin C in highly myopic eyes - Author reply
No full textOphthalmology. 2005 Feb;112(2):208-18; discussion 219.
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.
SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy.
Abstract
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes.
DESIGN: Prospective, double-masked, randomized clinical trial.
PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia.
METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months).
MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH.
RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively).
CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK.
Comment in
Ophthalmology. 2006 Feb;113(2):357; author reply 357-8
How, i f you don't from sin retire,
No full textmandolins; voiceGene and Idis Neal
Wesley, Arkansas
April 13, 1951
Collected by Irene Carlisle
Reel 110 Item 5
WHEN HE SETS YOUR FIELDS ON FIRE
There's a call that rings; what a wondrous thing
To folks that's gone astray;
Saying, "Come, ye men with your load of sin;
There at the altar lay."
You don't seem to heed, nor your chain of greed,
Your conscience never retire;
Be assured, my friend, if you s t i l l offend,
He will set this world on f i r e .
How, i f you don't from sin retire,
He will set your fields on f i r e;
You have heard Jesus c a l l,
And he says your soul must f a l l.
Now, my friends, if you desire,
He will set your fields on f i r e;
And rejoice with him, free from every sin,
When he sets this world on f i r e.
Won't you take advice, make the sacrifice,
Completely turn from sin?
Taking up the cross, counting treasures lost,
Let Jesus live within.
When temptations come, you can face toward home;
Your heart will never tire;
But rejoice and pray in that last great day
When he sets this world on f i r e .
How, i f you don't, etc.Funding for digitization provided by the Arkansas Humanities Council and the Happy Hollow Foundation
Six Overtures Composed by C. F. Abel. Adapted for the Harpsichord or Piano Forte : being Opera First / By the Author
Get PDFSIX OVERTURES COMPOSED BY C. F. ABEL. ADAPTED FOR THE HARPSICHORD OR PIANO FORTE : BEING OPERA FIRST / BY THE AUTHOR
Six Overtures Composed by C. F. Abel. Adapted for the Harpsichord or Piano Forte : being Opera First / By the Author (1)
Cover (1)
Titelseite (2)
Overture I. (3)
Overture II. (8)
Overture III. (12)
Overture IV. (16)
Overture V. (20)
Overture VI. (24
F. Poindexter to C. S. Buchanan, November 12, 1864
No full textIn this letter of November 12, 1864, Adgt. F. Poindexter informs Captain C. S. Buchanan for Colonel J. P. Siler that he needs to have his men ready and assembled to defend the country. He also requires Buchanan to stop by Headquarters so he can fill out a requisition for number of arms and amount of ammunition needed.Head Quarters 6th Reg. NC, H, S,
Franklin Nov, 12th 1864
Special Orders
No.___
Capt. C. S. Buchanan,
I am instructed by Col. Siler to inform you that he has just received special orders from Col. Palmer, to direct you to have your men in readiness to be assembled at any time when called upon by Col. Siler & to cooperate with him in defending the country, in such a way as Col. Siler shall indicate. I am also instructed by Col. Siler to inform you that he has a blank Requisition for arms, ammunition [all] for your company of Reserves. You are therefore, respectively, required, to come over to these Head Quarters at once, to make out the Requisition, indicated above, for the number of arms & amount of ammunition necessary, for your company. Please act promply.
By order of
Capt. C.S. Buchanan Col. J.P. Siler
Commanding Reserve F. Poindexter Adgt.
In Jackson & Maco
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