363 research outputs found
Kumba gymnorhynchus Iwamoto and Sazonov 1994
No full textKumba gymnorhynchus Iwamoto and Sazonov, 1994 Fig 5 Kumba gymnorhynchus Iwamoto and Sazonov, 1994: 229 –231, fig. 3, 4 (holotype CAS 77313, 68.3 HL, 402 + TL) and paratype ZMMGU P. 17766 (75.3 HL, 496 + TL); West Australian Ridge [Broken Ridge], 30 ° 46 ’S, 93 ° 20 ’E; 1260– 1370 m; 2 Sep 1976. Shao et al. 2008: 25, table 2 (listed, one spec.; South China Sea, 736–1040 m) Material examined. ASIZ P 65527 (1 spec., 64.9 HL, 316 TL; South China Sea, 22 ° 16 ’N, 120 °06’E, 736– 1040 m; sta. CD 134; 22 Nov 2001). Counts. 1 D II, 11; P i 18 /i 18; V 8; gillrakers first arch (outer/inner) 1 + 6 / 1 + 9, gillrakers second arch (outer/inner) 2 + 9 / 2 + 8; scale rows below 1 D 11, below midbase 1 D 9, below 2 D 12, lateral line scales over distance equal to predorsal length ca. 52. Measurements (in mm, percent HL in parentheses). Head length 64.9; snout 17.8 (27); preoral 13.4 (21); internasal width 14.0 (22); interorbital width 15.7 (24); orbit diameter 16.9 (26); suborbital height 10.3 (16); postorbital length 25.7 (40); distance orbit to preopercle 32.2 (50); length upper jaw 26.9 (41); length barbel 7.6 (12); length isthmus to A origin 28.7 (44); height 1 D 41.3 (64); length base 1 D 20.1 (31); P length 34.7 (53); length V 54.1 (83). Remarks. This specimen represents the first record of the species from the western Pacific and only the third known specimen. The original description was based on two specimens collected from the West Australian Ridge in the eastern Indian Ocean. Another specimen was examined by the first author in the Museum of Victoria (NMV 23944, 61 mm HL, 360 mm TL); it was captured off Albany, Western Australia (35 °S, 118 °E). The species is also expected to be in the southwestern Pacific.Published as part of Iwamoto, Tomio, Ho, Hsuan-Ching & Shao, Kwang-Tsao, 2009, Description of a new Coelorinchus (Macrouridae, Gadiformes, Teleostei) from Ta i w a n, with notable new records of grenadiers from the South China Sea, pp. 39-50 in Zootaxa 2326 on page 48, DOI: 10.5281/zenodo.27542
Summary of report of bulletins from March 26, 1942 to June 31, 1942
No full textSummary of the report on bulletins written by Kiyotoshi Iwamoto. Summary covers staff, activities, and number of bulletins.The Tsuyoshi Roy Nakai Collection includes reports and and handwritten notes related to the Manzanar incarceration camp and the Nakai family
Sociology essay
No full textSociology essay written by Sawae Iwamoto for a class assignment at Tri-State High School at Tule Lake incarceration camp. Covers population and it's impact on community life.The Japanese American Archival Collection documents the people, places, and daily life of Japanese Americans, primarily those who lived in the once thriving community of pre-war Florin in the Sacramento region, as well as the conditions in American incarceration camps during World War II. The approximately 7,000 original items include personal and official letters, photographs, diaries, arts and crafts, newsletters, textiles, camps artifacts, yearbooks and other publications
Memo from Shyogo Iwamoto, Secretary, Heart Mountain Community Council, to Mr. Shoji Nagumo, February 11, 1944
No full textMemorandum of understanding regarding the date, time, and location of a council meeting.The Japanese American Archival Collection documents the people, places, and daily life of Japanese Americans, primarily those who lived in the once thriving community of pre-war Florin in the Sacramento region, as well as the conditions in American incarceration camps during World War II. The approximately 7,000 original items include personal and official letters, photographs, diaries, arts and crafts, newsletters, textiles, camps artifacts, yearbooks and other publications
Cytostatic inhibition of cancer cell growth by lignan secoisolariciresinol diglucoside
No full textOur previous study demonstrated that lignan metabolites enterolactone and enterodiol inhibited colonic cancer cell growth by inducing cell cycle arrest and apoptosis. However, the dietary lignans are naturally present as glycoside precursors, such as secoisolariciresinol diglucoside (SDG), which have not been evaluated yet. This study tested the hypothesis that dietary SDG might have a different effect than its metabolites in human colonic SW480 cancer cells. Treatment with SDG at 0 to 40 μmol/L for up to 48 hours resulted in a dose- and time-dependent decrease in cell numbers, which was comparable to enterolactone. The inhibition of cell growth by SDG did not appear to be mediated by cytotoxicity, but by a cytostatic mechanism associated with an increase of cyclin A expression. Furthermore, high-performance liquid chromatography analysis indicated that SDG in the media was much more stable than enterolactone (95% of SDG survival vs 57% of enterolactone after 48-hour treatment). When the cells were treated with either enterolactone or SDG at 40 μmol/L for 48 hours, the intracellular levels of enterolactone, as measured by high-performance liquid chromatography–mass spectrometry/electron spray ionization, were about 8.3 × 10−8 nmol per cell; but intracellular SDG or potential metabolites were undetectable. Taken together, SDG demonstrated similar effects on cell growth, cytotoxicity, and cell cycle arrest when compared with its metabolite enterolactone. However, the reliable stability and undetectable intracellular SDG in treated cells may suggest that metabolism of SDG, if exposed directly to the colonic cells, could be different from the known degradation by microorganisms in human gut
Structural and biophysical properties of a synthetic channel-forming peptide: designing a clinically relevant anion selective pore
No full textThe design, synthesis, modeling and in vitro testing of channel-forming peptides derived from the cys-loop superfamily of ligand-gated ion channels are part of an ongoing research focus. Over 300 different sequences have been prepared based on the M2 transmembrane segment of the spinal cord glycine receptor α-subunit. A number of these sequences are water-soluble monomers that readily insert into biological membranes
where they undergo supramolecular assembly, yielding channels with a range of selectivities and conductances. Selection of a sequence for further modifications to yield an optimal lead compound came
down to a few key biophysical properties: low solution concentrations that yield channel activity, greater ensemble conductance, and enhanced ion selectivity. The sequence NK[subscript]4-M2GlyR T19R, S22W (KKKKPARVGLGITTVLTMRTQW) addressed these criteria. The structure of this peptide has been analyzed by solution NMR as
a monomer in detergent micelles, simulated as five-helix bundles in a membrane environment, modified by cysteine-scanning and studied for insertion efficiency in liposomes of selected lipid compositions. Taken together, these results define the structural and key biophysical properties of this sequence in a membrane. This model provides an initial scaffold from which rational substitutions can be proposed and tested to modulate anion selectivity. This article is part of a Special Issue entitled: Protein Folding in Membranes
Thorogobius alvheimi Sauberer & Iwamoto & Ahnelt 2018, sp. nov.
No full textThorogobius alvheimi sp. nov. (Figures 1–3, 7; Tables 1–3) Holotype. CAS 222482, female, standard length+caudal fin length 72.1+ 19.8 mm; Angola, off Luanda (8°24′S, 12°56′E) at depths of 166– 162 m, R/ V Dr. Fridtjof Nansen (DFN) stn. 3713, 15 April 2005. Paratypes. (8 specimens). Angola: CAS 222338, 1 male 51.8+d mm SL+CL, 1 female 52.3+d mm SL+CL, sw. of Congo R. mouth (6°27′S, 11°55′E), 109– 108 m, DFN stn. 3783, 22 April 2005; CAS 244059, 1 male 102.4+d mm SL+CL, same data as for holotype; CAS 225193, 1 female 52.2+d mm SL+CL, off Luanda (8°53.5′S, 13°02.21′E) 190– 187 m, DFN stn. 102, 11 March 2007; NMW 99079, 1 female 62.6+ 20.2 mm SL+CL, same data as for CAS 222338. Ghana: CAS 243855, 1 female 64.1+ 17.4 mm SL+CL, off Accra (5°16.44′N, 0°10.65′W), 91– 88 m, DFN stn. 13, 2 May 2010; CAS 243856, 1 male 51.3+ 15.3 mm SL+CL, off Keta (5°49.26′N, 1°07.57′E), 84– 74 m, DFN stn.4, 1 May 2010; CAS 243857, 1 female 58.6 + d mm SL+CL, se. off Keta, (5°53.89′N, 1°16.37′E), 208– 201 m, DFN stn. 2, 2 May 2010. Non-type specimens. (4 specimens). Excluded from type material because of damage and/or juvenile stage. CAS 244060, 4 specimens of undetermined sex (37.9–46.5 mm SL), same data as for holotype. Diagnosis. Thorogobius alvheimi sp. nov. is distinguished from its congeners in the combination of following characters: Fins: first dorsal fin with six spiny rays, second and third distinctly elongated; pectoral fin ray count 20–21; pelvic disc complete and short with well-developed anterior membrane (frenum), with pointed lateral lobes. Scales: nape and predorsal area naked; no scales on the opercle; scales in longitudinal series 27–31. Pattern of free neuromasts: supratemporal rows tr and trp developed, extending transversally between pores H and K; longitudinal row g short, not passing row m posteriorly and distinctly distant from row h; infraorbital row 6 long, ventrally extending to lower margin of preopercle, its ventral section 6i originating anterior to its dorsal section 6s; posterior lateral row h reaching anteriorly above posterior third of opercle. Body proportions: body depth (16.6– 20.4% at anal-fin origin in SL), head width (42.9–53.8% in head length); upper jaw long (42.6–45.7% in head length); minimum height of caudal peduncle (34.8–50.2% in caudal peduncle length); eyes large (22.4–31.3% in head length); caudal fin short (27.1–32.3% in SL). Coloration: body uniformly pale fawn and brown; margin of scale pockets dark brown pigmented, yielding a reticulated pattern; pale spots on nape and predorsal area; caudal fin uniformly dusky greyish. Description. Profile of head steep; dorsal outline of body straight. Tubular anterior nostril short without process from rim; branchiostegal membrane attached to side of isthmus. Fins. D1 with 6 spiny rays (6*: 9); D2 with 1 spiny and 11 articulated rays (1+11*: 9); anal fin with 1 spiny and 10 articulated rays (1+10*: 9); pectoral fin with 20–21 articulated rays (20*: 7, 21: 2); dorsalmost rays of pectoral fin within fin membrane; pelvic disc with 1 spiny and 5 articulated rays on each side (1+5*: 9); caudal fin with 16– 17 segmented rays (16*: 1, 17: 8), 14 of them branched (14*: 9). Second to fourth spiny rays of D1 longest; second spiny ray of D1 extremely elongated, when depressed reaching to end of D2 base; depressed third dorsal spiny ray reaching approximately to first quarter of D2 base. Pelvic disc complete (oval-shaped) with well-developed anterior membrane (frenum) that extends about 75% of first (spinous) ray; lobes distinct, narrow and pointed. Squamation. Scales in lateral series 27–31 (27: 2, 28: 1, 29*: 3, 30: 1, 31: 1); scales in transversal series 8–11 (8:2; 9: 1; 10*: 1, 11: 1). Entire trunk, breast and base of pectoral fin covered by large scales. Predorsal area, nape, cheek and opercle naked (Fig. 3). ......continued on the next page Dentition. Premaxillary teeth arranged in an outer row of distinctly larger canine teeth and 5–6 rows of small conical teeth; on dentary some teeth of anteriormost row enlarged and caniniform, followed by series of 5–6 intermediate rows of small conical teeth and innermost row of enlarged teeth. Gill-rakers (holotype). Eight gill-rakers on ceratobranchial bone; one on epibranchial and one on pharyngobranchial. Vertebrae. Total number 28; 11 precaudal and 17 caudal, including urostyle. Body proportions. Presented in table 2. Head lateral line system (Fig. 3). Anterior and posterior oculoscapular canals complete with pores (from anterior to posterior) B, C (unpaired), D (unpaired), E, F, G, H and K, and L, respectively. Preopercular canal with pores (from dorsal to ventral) M, N and O; these pores larger than pores of other head canals. Rows and number of neuromasts (sensory papillae) given in table 1. Generally a high number of papillae present in most of the neuromast rows. Coloration (preserved in ethanol). Body pale fawn and brown; head, including nape and predorsal area, darker than trunk; lips not distinctly darker than head; nape and predorsal area with pale spots in a reticulate pattern over dark ground laterally extending onto dorsal part of opercle; neuromasts (sensory papillae) dark brown; margin of scale pockets dark brown, yielding a reticulated pattern. Trunk uniformly pale fawn to brownish; no dark patches at the bases of dorsal fins; caudal, pectoral and pelvic fins uniformly dusky greyish (Figs. 2, 3). Etymology. This species is named in honor of Oddgeir Alvheim of the Institute of Marine Research, Bergen, Norway, for his many photographic contributions to the FAO Species Identification Guides and for his assistance and advice to the second author during three surveys aboard the R/V Dr. Fridtjof Nansen. Distribution and habitat. So far Thorogobius alvheimi sp. nov. is known only from the type localities off Angola and Ghana. It was dredged on the outer edge of the continental shelf from 208– 74m depth and occurs on soft bottom. Remarks. Thorogobius alvheimi sp. nov. differs distinctly from other species of the genus in the following specific characters (also see table 3 for an additional character matrix). Thorogobius alvheimi sp. nov. and Thorogobius angolensis differ in: (1) squamation of nape and predorsal area and dorsal part of opercle (naked vs. completely scaled) (Fig. 7); (2) number of neuromasts in head neuromast rows (less numerous and shorter vs. numerous and longer), e.g. row i1 (10–12 vs. 19–25); coloration (preserved) of (3) trunk (uniformly pale fawn to brownish with no distinct markings vs. pale fawn to brownish with two brown blotches on flanks in lateral midline below rear of D1 and center of D2, respectively); of (4) nape and predorsal area (with pale spots in a reticulate pattern over dark ground extending onto dorsal part of opercle vs. no spots on nape, predorsal area or opercle); of (5) pectoral fin (no dark vertical band on dorsal half of pectoral fin base vs. dark band on base of pectoral fin); (6) caudal fin uniformly dusky greyish vs. 4–5 vertical dark bands. Thorogobius alvheimi sp. nov. and Thorogobius ephippiatus differ in: (1) scales in lateral midline (27–31 vs. 33–42); (2) lobe of pectoral fin (scaled vs. naked); (3) neuromast rows tr and trp (present vs. absent); coloration (preserved) of (4) head, nape and predorsal area (pale spots in a reticulate pattern on nape and predorsal area only vs. brown spots on head, nape and predorsal area); of (5) trunk (uniformly pale fawn to brownish with no distinct markings vs. covered with dark brown blotches); (6) habitat preference (offshore between 74 and 208 m on soft bottoms vs. inshore in 6–60 m on sandy areas of rocky shores, also cave dwelling); (7) distribution (off Angola and Ghana vs. Norwegian Sea to Canary Islands). Thorogobius alvheimi sp. nov. and Thorogobius laureatus sp. nov. differ in: (1) squamation of nape and predorsal area (naked vs. sides of nape and predorsal area scaled) (Figs. 3, 5, 7); (2) pattern of the head neuromast lateral line system (distance between rows g and h as least as long as row g vs. distance between both rows halflength of row g or less; row 6i originates anterior to 6s vs. rows 6i and 6s opposite to each other); coloration (preserved) of (3) nape and predorsal area (with pale spots in a reticulate pattern over dark ground laterally extending on dorsal part of opercle vs. no spots on nape and predorsal area) (Figs. 3, 5); of (4) pectoral fin (no dark vertical band on dorsal half of pectoral fin base vs. dark band on base of pectoral fin) (Figs. 2, 4, 6); of (5) caudal fin (uniformly dusky greyish vs. with 6–7 distinct dark vertical bands) (Figs. 2, 6). Thorogobius alvheimi sp. nov. and Thorogobius macrolepis differ in: (1) number of pectoral fin rays (20–21 vs. 17–18); (2) number of neuromasts in head neuromast rows, e.g. r2 (11–20 vs. 4–8), c 2 (16–24 vs. 8–13), 3 (12– 22 vs. 8–11), 4 (16–25 vs. 9–13), e1 (32–46 vs. 24–29), f (17–29 vs. 10–15), as1 (16–22 vs. 7–11), la2 (8 vs. 3–7); (3) lobe of pectoral fin (scaled vs. naked); (4) neuromast rows tr and trp (present vs. absent); coloration (preserved) of (5) head, nape and predorsal area (pale spots in reticulate pattern on nape and predorsal area only vs. brown spots on head, nape and predorsal area); of (6) trunk (uniformly pale fawn to brownish with no distinct markings vs. covered with pale spots and blotches); (7) habitat preference (offshore between 74 and 208 m on soft bottom vs. inshore in 6–60 m on sandy areas of rocky shores, also cave dwelling); (8) distribution (off Angola and Ghana vs. from the Mediterranean). Thorogobius alvheimi sp. nov. and Thorogobius rofeni differ in: (1) neuromast rows tr and trp (present vs. absent); (2) number of neuromasts in head neuromast rows, e.g. r2 (11–20 vs. 5–8), h (18–35 vs. 12–17), as1 (16– 23 vs. 10–13), la2 (8 vs. 4–5); (3) upper jaw longer (42.6–45.7% vs. 33.0–37.2% in head length); (4) coloration (preserved) of (5) nape and predorsal area (with pale spots in a reticulate pattern over dark ground laterally extending on dorsal part of opercle vs. no spots on nape and predorsal area); of (6) caudal fin (uniformly dusky greyish vs. with distinct dark vertical bands).Published as part of Sauberer, Michael, Iwamoto, Tomio & Ahnelt, Harald, 2018, Two new deep-water species of the genus Thorogobius (Teleostei: Gobiidae) from the upper continental slope of the Eastern Central Atlantic, pp. 357-371 in Zootaxa 4429 (2) on pages 360-366, DOI: 10.11646/zootaxa.4429.2.10, http://zenodo.org/record/128391
Tyr-199 and charged residues of pharaonis Phoborhodopsin are important for the interaction with its transducer.
No full textpharaonis Phoborhodopsin (ppR; also pharaonis sensory rhodopsin II, psRII) is a retinal protein in Natronobacterium pharaonis and is a receptor of negative phototaxis. It forms a complex with its transducer, pHtrII, in membranes and transmits light signals by protein-protein interaction. Tyr-199 is conserved completely in phoborhodopsins among a variety of archaea, but it is replaced by Val (for bacteriorhodopsin) and Phe (for sensory rhodopsin I). Previously, we (Sudo, Y., M. Iwamoto, K. Shimono, and N. Kamo, submitted for publication) showed that analysis of flash-photolysis data of a complex between D75N and the truncated pHtrII (t-Htr) give a good estimate of the dissociation constant KD in the dark. To investigate the importance of Tyr-199, KD of double mutants of D75N/Y199F or D75N/Y199V with t-Htr was estimated by flash-photolysis and was ~10-fold larger than that of D75N, showing the significant contribution of Tyr-199 to binding. The KD of the D75N/t-Htr complex increased with decreasing pH, and the data fitted well with the Henderson-Hasselbach equation with a single pKa of 3.86 ± 0.02. This suggests that certain deprotonated carboxyls at the surface of the transducer (possibly Asp-102, Asp-104, and Asp-106) are needed for the binding
Implementing displacement damage calculations for electrons and gamma rays in the Particle and Heavy-Ion Transport code System
No full textCore size effects of laser fusion subcritical research reactor for fusion engineering research
No full textA multi-purpose high repetition laser facility, the so-called Japan establishment for power-laser community harvest (J-EPoCH) is proposed as a next generation laser facility. J-EPoCH will operate at the maximum rate of 100 Hz. The omnidirectional 12 laser beams with 8 kJ would yield ∼1013 neutrons with a large high aspect ratio target. As one of the applications of J-EPoCH, a laser fusion subcritical research reactor has been conceptually designed based on existing technologies. Moreover, a variety of fusion engineering studies: energy conversion, tritium breeding, neutron irradiation effects, etc, can be conducted. The feasibility of the subcritical research reactor is considered in terms of neutron-thermal (n-t) conversion and tritium breeding. Lead–lithium alloy (Li17Pb83) and boron carbide (B4C) have the potential to be studied for preliminary fusion power generation. The subcritical reactor will generate 21.4 W and 20.0 W of the thermal fusion power with the Li17Pb83 and the B4C layers of the thickness of 80 cm, respectively at 1 Hz operation. The Li17Pb83 layer of a 5 mm thickness will achieve the temperature rise of 0.203 mK per shot. The thermal fusion energy is detectable with conventional measurement techniques. The core with the Li17Pb83 layer thickness of 100 cm will yield more than one tritium from a deuterium–tritium fusion neutron. However, laser windows reduce the efficiency of n-t conversion and tritium yield.** After this version, the author still has made a few minor corrections.journal articl
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