867 research outputs found
Anti-apoptotic Effects of PCP4/PEP19 in Human Breast Cancer Cell Lines: A Novel Oncotarget
No full text博士論文全文, 博士論文要旨Taiji Hamada, Masakazu Souda, Takuya Yoshimura, Shoko Sasaguri, Kazuhito Hatanaka, Takashi Tasaki, Takako Yoshioka, Yasuyo Ohi, Sohsuke Yamada, Masato Tsutsui, Yoshihisa Umekita and Akihide Tanimoto
Anti-apoptotic Effects of PCP4/PEP19 in Human Breast Cancer Cell Lines: A Novel Oncotarget
Oncotarget. 2014; 5(15):6076-6086.
https://doi.org/10.18632/oncotarget.216
Low energy indium or gallium ion implantations to SiO2 thin films for development of novel catalysts
No full textSatoru Yoshimura, Masato Kiuchi, Yoshihiro Nishimoto, Makoto Yasuda, Akio Baba, Satoshi Hamaguchi, Low Energy Indium or Gallium Ion Implantations to SiO2 Thin Films for Development of Novel Catalysts, e-Journal of Surface Science and Nanotechnology, 2014, Volume 12, Pages 197-202, Released April 26, 2014, Online ISSN 1348-0391, https://doi.org/10.1380/ejssnt.2014.197, https://www.jstage.jst.go.jp/article/ejssnt/12/0/12_197/_article/-char/enIt has been demonstrated that indium (In) implanted silicon dioxide (SiO thin films catalyze a reaction of benzhydrol with acetylacetone. In this study, it is found that the threshold In ion incident energy for manifestation of the catalytic effect exists between 400 and 470 eV. Furthermore, a technique to implant gallium (Ga) to SiOfilms has been developed with highly controlled doses and injection energies for the formation of thin films that promote Ga catalysts. The efficiency of catalytic reactions by Ga implanted SiOthin films is yet to be improved. Unlike In implanted SiO2, the reason why no significant reaction was observed in the case of Ga implanted SiOfilms examined in this study seems that the Ga ion energy was so low that deposited surface Ga atoms should lack interactions with Si atoms for the manifestation of catalytic reaction. © 2014 The Surface Science Society of Japan
ヒト乳癌細胞におけるPCP4/PEP19の抗アポトーシス作用 : 新規の癌標的分子
No full text鹿児島大学博士(医学)Doctor of Philosophy in Medical Science博士論文全文, 博士論文要旨Taiji Hamada, Masakazu Souda, Takuya Yoshimura, Shoko Sasaguri, Kazuhito Hatanaka, Takashi Tasaki, Takako Yoshioka, Yasuyo Ohi, Sohsuke Yamada, Masato Tsutsui, Yoshihisa Umekita and Akihide Tanimoto
Anti-apoptotic Effects of PCP4/PEP19 in Human Breast Cancer Cell Lines: A Novel Oncotarget
Oncotarget. 2014; 5(15):6076-6086.
https://doi.org/10.18632/oncotarget.2161doctoral thesi
Low-energy O⁺ or SiO⁺ ion beam induced deposition of silicon oxide using hexamethyldisiloxane
No full textYoshimura S., Takeuchi T., Kiuchi M.. Low-energy O⁺ or SiO⁺ ion beam induced deposition of silicon oxide using hexamethyldisiloxane. Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms 549, 165276 (2024); https://doi.org/10.1016/j.nimb.2024.165276.We attempted to form silicon oxide films by spraying hexamethyldisiloxane (HMDSO) to a substrate together with low-energy O⁺ ion beam injections. The energy of O⁺ ions was 100 eV. The substrate temperature was set at room temperature. After the trial, we found a film deposited on the substrate. X-ray photoelectron spectroscopy (XPS) measurements of the film showed that the film was silicon dioxide. The XPS spectra of the film also showed that the film contained almost no carbon atoms. For comparison, 100 eV SiO⁺ ion beams were injected into a substrate at room temperature in conjunction with HMDSO. XPS results of the deposited film showed that the film was silicon oxide and the atomic concentration ratio of oxygen to silicon was 1.35. In this case, however, a relatively large amount of carbon atoms (12 atomic%) was included in the film. In conclusion, we confirmed that the 100 eV O⁺ ion beam induced deposition using HMDSO is useful for the silicon dioxide film formation
Deposition of germanium dioxide films by the injection of oxygen ion beam in conjunction with hexamethyldigermane
No full textYoshimura S., Sugimoto S., Takeuchi T., et al. Deposition of germanium dioxide films by the injection of oxygen ion beam in conjunction with hexamethyldigermane. Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 1056, 168707 (2023); https://doi.org/10.1016/j.nima.2023.168707.We proposed a methodology for fabricating a film by the simultaneous injections of O+ ions and hexamethyldigermane (HMDG) to a substrate. The O+-ion energy was set at 50 eV. After the experimental trial, we found a film deposited on the substrate. The analyses of the film with X-ray photoelectron spectroscopy and Fourier transform infrared spectroscopy showed that the deposited film was germanium dioxide (GeO2). It was also noted that no film deposition occurred when HMDG was supplied to substrates without O+-ion beam injections. In conclusion, the low-energy O+-ion beam induced deposition using HMDG was found to be useful for the deposition of GeO2 films
Deposition of germanium dioxide films by the injection of oxygen ion beam in conjunction with hexamethyldigermane
No full textYoshimura S., Sugimoto S., Takeuchi T., et al. Deposition of germanium dioxide films by the injection of oxygen ion beam in conjunction with hexamethyldigermane. Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 1056, 168707 (2023); https://doi.org/10.1016/j.nima.2023.168707.We proposed a methodology for fabricating a film by the simultaneous injections of O+ ions and hexamethyldigermane (HMDG) to a substrate. The O+-ion energy was set at 50 eV. After the experimental trial, we found a film deposited on the substrate. The analyses of the film with X-ray photoelectron spectroscopy and Fourier transform infrared spectroscopy showed that the deposited film was germanium dioxide (GeO2). It was also noted that no film deposition occurred when HMDG was supplied to substrates without O+-ion beam injections. In conclusion, the low-energy O+-ion beam induced deposition using HMDG was found to be useful for the deposition of GeO2 films
Crystal structure of infectious bursal disease virus VP2 subviral particle at 2.6 ? resolution: Implications in virion assembly and immunogenicity
No full text社会資本によるスピルオーバー効果と地域経済成長 : 市町村データを用いた高速道路整備効果の実証分析
No full text本研究では, 日本の非都心地域への高速道路整備に焦点を当てながら, Chandra and Thompson (2000) の手法をべ一スに, 社会資本整備がもたらす地域経済への広域的な成長効果を推定する。この手法の特徴は空間的位置に応じて地域を分類することで, 内生性の問題に対処しながら高速道路整備の持つ広域的な地域間スピルオーバー効果を識別する点にある。実証分析の結果, 道路整備の地方都市への長期的な成長効果が確認されたが, 産業別にみると製造業や卸売業にはプラスの成長をもたらすものの, 農業や小売業にはマイナスの影響をもたらすことが明らかとなった。さらに, 高速道路の整備地域に比べ, そこから離れた隣接地域ほどより大きな成長効果があらわれる一方で, さらに離れた隣々接地域には負のスピルオーバー効果が見られることが示された。以上の結果は, 広域的なインパクトをもたらす社会資本整備においては, そのインフラが整備される地域のみならず, その周辺地域への影響を考慮することの重要性を示唆している
Serotonin (5-HT3) receptor antagonists for the reduction of symptoms of low anterior resection syndrome
No full textRyohei Itagaki, Keiji Koda, Masato Yamazaki, Kiyohiko Shuto, Chihiro Kosugi, Atsushi Hirano, Hidehito Arimitsu, Risa Shiragami, Yukino Yoshimura, Masato Suzuki Department of Surgery, Teikyo University Chiba Medical Center, Anesaki, Ichihara, Chiba, Japan Purpose: Serotonin (5-hydroxytryptamine [5-HT])3 receptor antagonists are effective for the treatment of diarrhea-predominant irritable bowel syndrome (IBS-D), in which exaggerated intestinal/colonic hypermotility is often observed. Recent studies have suggested that the motility disorder, especially spastic hypermotility, seen in the neorectum following sphincter-preserving operations for rectal cancer may be the basis of the postoperative defecatory malfunction seen in these patients. We investigated the efficacy of 5-HT3 receptor antagonists in patients suffering from severe low anterior resection syndrome. Patients and methods: A total of 25 male patients with complaints of uncontrollable urgency or fecal incontinence following sphincter-preserving operations were enrolled in this study. Defecatory status, assessed on the basis of incontinence score (0–20), urgency grade (0–3), and number of toilet visits per day, was evaluated using a questionnaire before and 1 month after the administration of the 5-HT3 antagonist ramosetron. Results: All the parameters assessed improved significantly after taking ramosetron for 1 month. The effect was more prominent in cases whose anastomotic line was lower, ie, inside the anal canal. Defecatory function was better in patients who commenced ramosetron therapy within 6 months postoperatively, as compared to those who were not prescribed ramosetron for more than 7 months postoperatively. Conclusion: These results suggest that 5-HT3 antagonists are effective for the treatment of low anterior resection syndrome, as in diarrhea-predominant irritable bowel syndrome. The improvement in symptoms is not merely time dependent, but it is related to treatment with 5-HT3 antagonists. Keywords: low anterior resection syndrome, serotonin receptor antagonist, ISR, defecatory malfunctio
Correction to: Comparison of glycyrrhizin content in 25 major kinds of Kampo extracts containing Glycyrrhizae Radix used clinically in Japan
No full textThe article Comparison of glycyrrhizin content in 25 major kinds of Kampo extracts containing Glycyrrhizae Radix used clinically in Japan, written by Mitsuhiko Nose, Momoka Tada, Rika Kojima, Kumiko Nagata, Shinsuke Hisaka, Sayaka Masada, Masato Homma and Takashi Hakamatsuka, was originally published Online First without open access. After publication in volume 71, issue 4, page 711–722 the author decided to opt for Open Choice and to make the article an open access publication. Therefore, the copyright of the article has been changed to © The Author(s) 2018 and the article is forthwith distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, duplication, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.</jats:p
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