27,563 research outputs found
Liu Kang
No full textLiu Kang: Essays on Art and Culture is a testament to the inexorable passion of an artist who knew no boundaries. This collection of essays, which Liu Kang wrote over 44 years, offers an insight into the artist’s myriad interests as well as his contributions as a first generation Nanyang artist and art educator. Translated into English for this volume, Liu Kang’s essays are accompanied by commentaries and photographs of the artist-author and his subjects
sj-docx-7-dhj-10.1177_20552076231203648 - Supplemental material for Systemic evaluation of the relationship between asthma and osteoarthritis: Evidence from a meta-analysis and Mendelian randomization study
No full textSupplemental material, sj-docx-7-dhj-10.1177_20552076231203648 for Systemic evaluation of the relationship between asthma and osteoarthritis: Evidence from a meta-analysis and Mendelian randomization study by Yaoyao Nie, Houpu Liu, Jing Wang, Ye Yang, Wenxia Zhao, Dingwan Chen and Yingjun Li in DIGITAL HEALTH</p
sj-docx-8-dhj-10.1177_20552076231203648 - Supplemental material for Systemic evaluation of the relationship between asthma and osteoarthritis: Evidence from a meta-analysis and Mendelian randomization study
No full textSupplemental material, sj-docx-8-dhj-10.1177_20552076231203648 for Systemic evaluation of the relationship between asthma and osteoarthritis: Evidence from a meta-analysis and Mendelian randomization study by Yaoyao Nie, Houpu Liu, Jing Wang, Ye Yang, Wenxia Zhao, Dingwan Chen and Yingjun Li in DIGITAL HEALTH</p
sj-tiff-1-tag-10.1177_17562848241245455 – Supplemental material for In era of immunotherapy: the value of trastuzumab beyond progression in patients with trastuzumab-resistant HER2-positive advanced or metastatic gastric cancer
No full textSupplemental material, sj-tiff-1-tag-10.1177_17562848241245455 for In era of immunotherapy: the value of trastuzumab beyond progression in patients with trastuzumab-resistant HER2-positive advanced or metastatic gastric cancer by Hui Wang, Caiyun Nie, Weifeng Xu, Jing Li, He Gou, Huifang Lv, Beibei Chen, Jianzheng Wang, Yingjun Liu, Yunduan He, Jing Zhao and Xiaobing Chen in Therapeutic Advances in Gastroenterology</p
Phoebus 10: A Journal of Art History
No full texttableOfContents: Homage to the Past: The Art of Yin Xiaofeng by Ralph Gabbard and Liu Liu.. pages 5-1
Resilience enhancement for urban distribution network via risk-based emergency response plan amendment for ice disasters
No full textHigh-impact low-probability (HILP) events, such as ice disasters, result in large losses of critical loads (CLs) in the urban distribution network (UDN). Thus, emergency response plans are usually made against various HILP events to improve the UDN resilience. However, these emergency plans are usually made under incomplete and imperfect information; thus, the execution of these plans may not be effective and even risky under the real situation. Therefore, in this paper, a multi-stage UDN resilience enhancement framework is proposed for tackling this challenge. At the first stage, the distribution system operator (DSO) forms typical failure scenarios based on historical data of damage to electric components under ice disasters. Under each scenario, the DSO designs a response plan to minimize the CLs' loss and associated costs. Thanks to the updated information on the ice disaster, at the second stage, DSO makes a risk assessment on the planned emergency response. If the risk is unacceptable for any period of the ice disaster, at the third stage, DSO amends the response plan to alleviate the "second-order " impacts on CLs, distribution lines, and distributed generations (DGs). Finally, simulations on the modified IEEE-69 system, including 10 CLs and some DGs, show that the proposed framework can effectively reduce second-order impacts due to both the ice disaster and its impact on the execution of originally planned emergency response
Cultural exploitation in chinese politics: Reinterpreting liu sanjie
No full textLiu Sanjie is a typical Chinese legendary figure, adapted from folk custom and transformed during many historical and political stages. By comparing the musical film Liu Sanjie with the landscape performing art Impression Liu Sanjie, this paper explores how Liu Sanjie is reconstructed in the Impression to be in accord with contemporary demands (shidaixing). In the film, made during the 1960s, Liu Sanjie was promoted as a heroine fighting against the privileged classes, but in the Impression, her class struggle has been erased and only a harmonious and abstract legend remains. Her ethnicity is promoted by Han elites as not exclusive Zhuang, but shared equally with Han, Miao and Dong ethnicity in an imagined community to propagate a sense of ethnic harmony and unified Chineseness. Her transformation from a realistic character, full of a rebelling spirit, to an abstract and disembodied ‘sense of harmony’, is a complete reinterpretation of a Chinese historical legend. Utilizing a term from Wang Ban (1997), ‘the sublime figure of history’, which refers to an ideology aestheticized by the party state for securing its governance, this paper refers to the bold artistic treatment of Liu Sanjie for cultural exploitation as ‘Liu Sanjie’s sublime’. The paper explores the evolutionary progress of Liu Sanjie from class revolution to art revolution in response to political requirements. The author is a stage-trained performing artist, specialized in both Western opera and Chinese classical and folk singing and dance. He is also a critic and art consultant in the Chinese landscape performing arts industry. These professional roles have allowed privileged access to the top people in this industry
Antimicrobial peptide novicidin synergizes with rifampin, ceftriaxone, and ceftazidime against antibiotic-resistant EnterobacteriaceaeIn Vitro
No full textThe spread of antibiotic resistance among Gram-negative bacteria is a serious clinical threat, and infections with these organisms are a leading cause of mortality worldwide. Traditional novel drug development inevitably leads to the emergence of new resistant strains, rendering the new drugs ineffective. Therefore, reviving the therapeutic potentials of existing antibiotics represents an attractive novel strategy. Novicidin, a novel cationic antimicrobial peptide, is effective against Gram-negative bacteria. Here, we investigated novicidin as a possible antibiotic enhancer. The actions of novicidin in combination with rifampin, ceftriaxone, or ceftazidime were investigated against 94 antibiotic-resistant clinical Gram-negative isolates and 7 strains expressing New Delhi metallo-?-lactamase-1. Using the checkerboard method, novicidin combined with rifampin showed synergy with >70% of the strains, reducing the MICs significantly. The combination of novicidin with ceftriaxone or ceftazidime was synergistic against 89.7% of the ceftriaxone-resistant strains and 94.1% of the ceftazidime-resistant strains. Synergistic interactions were confirmed using time-kill studies with multiple strains. Furthermore, novicidin increased the postantibiotic effect when combined with rifampin or ceftriaxone. Membrane depolarization assays revealed that novicidin alters the cytoplasmic membrane potential of Gram-negative bacteria. In vitro toxicology tests showed novicidin to have low hemolytic activity and no detrimental effect on cell cultures. We demonstrated that novicidin strongly rejuvenates the therapeutic potencies of ceftriaxone or ceftazidime against resistant Gram-negative bacteria in vitro. In addition, novicidin boosted the activity of rifampin. This strategy can have major clinical implications in our fight against antibiotic-resistant bacterial infections
Test Make Sense?
No full textCorresponding author Changyu Liu should be listed as the first corresponding author.No Full Tex
Nordihydroguaiaretic acid enhances the activities of aminoglycosides against methicillin-sensitive and resistant Staphylococcus aureus in vitro and in vivo
No full textInfections caused by methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant S. aureus (MRSA) are prevalent. MRSA infections are difficult to treat and there are no new classes of antibiotics produced to the market to treat infections caused by the resistant bacteria. Therefore, using antibiotic enhancers to rescue existing classes of antibiotics is an attractive strategy. Nordihydroguaiaretic acid (NDGA) is an antioxidant compound found in extracts from plant Larrea Tridentata. It exhibits antimicrobial activity and may target bacterial cell membrane. Combination efficacies of NDGA with many classes of antibiotics were examined by chequerboard method against 200 clinical isolates of MRSA and MSSA. NDGA in combination with gentamicin, neomycin, and tobramycin was examined by time-kill assays. The synergistic combinations of NDGA and aminoglycosides were tested in vivo using a murine skin infection model. Calculations of the fractional inhibitory concentration index (FICI) showed that NDGA when combined with gentamicin, neomycin, or tobramycin displayed synergistic activities in more than 97% of MSSA and MRSA, respectively. Time kill analysis demonstrated that NDGA significantly augmented the activities of these aminoglycosides against MRSA and MSSA in vitro and in murine skin infection model. The enhanced activity of NDGA resides on its ability to damage bacterial cell membrane leading to accumulation of the antibiotics inside bacterial cells. We demonstrated that NDGA strongly revived the therapeutic potencies of aminoglycosides in vitro and in vivo. This combinational strategy could contribute major clinical implications to treat antibiotic resistant bacterial infections
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