14,303 research outputs found
EZH2 as a Potential Target for NAFLD Therapy
No full textNon-alcoholic fatty liver disease (NAFLD) is a complex disease that is affected by genetic predisposition and epigenetic modification. Deregulation of epigenetic pathways is now recognized as a frequent event in NAFLD, and understanding the mechanistic roles of these epigenetic factors may lead to new strategies for NAFLD treatment. Enhancer of zeste homolog 2 (EZH2) catalyzes methylation on Lys 27 of histone H3, which leads to chromatin compaction and gene silencing. EZH2 regulates embryonic development and cell lineage determination and is related to many human diseases. Recent studies show that EZH2 has critical roles in liver development, homeostasis, and regeneration. Moreover, aberrant activation of EZH2 promotes NAFLD progression. Several EZH2 inhibitors have been developed and studied both in vitro and in clinical trials. In this review, we summarize our current understanding of the role of EZH2 in NAFLD and highlight its potential as a novel therapeutic target for NAFLD treatment
Author Correction: Evaluation of skin cancer resection guide using hyper‑realistic in‑vitro phantom fabricated by 3D printing
Get PDFThe original version of this Article contained an error in the spelling of the author Taehun Kim which was incorrectly given as Teahun Kim. The original Article has been corrected
Ouder, dus hoger in rang niet noodzakelijk meer van tel op de werkvloer
No full textAbstract: Speelt leeftijd in de huidige arbeidsmarkt nog steeds een belangrijke rol in hoe we binnen een bedrijf opklimmen? Recent onderzoek van professor Kim De Meulenaere, expert in organisatiegedrag en hr-management aan de Antwerp Management School en Universiteit Antwerpen, toont dat de relatie tussen leeftijd en hi\uebrarchische rang de prestaties van bedrijven be\uefnvloedt
Regularity results for nonlocal fully nonlinear elliptic equations
Get PDFRang M. Regularity results for nonlocal fully nonlinear elliptic equations. Bielefeld: Universitätsbibliothek; 2013.In this thesis we consider nonlocal fully nonlinear elliptic operators derived from a certain class of linear integro-differential operators with kernels having anisotropic lower bounds. We obtain regularity estimates for solutions to corresponding nonlocal fully nonlinear elliptic equations
DBLP-derived labeled data for author name disambiguation
No full textThis is a DBLP-derived labeled data originally created by Dr. C. Lee Giles at Penn State University and filtered for duplicate removal and error correction by Dr. Jinseok Kim at University of Michigan. For more details, see references below.1. Kim, Jinseok (2018). Evaluating author name disambiguation for digital libraries: a case of DBLP. Scientometrics. doi:10.1007/s11192-018-2824-5 2. Kim, Jinseok & Kim, Jenna (2018). The impact of imbalanced training data on machine learning for author name disambiguation. Scientometrics. doi: 10.1007/s11192-018-2865-9Each row refers to an author name instance with following feature information separated by tab.author name: full name string extracted from DBLPunique author id: labels assigned manually by Dr. C. Lee Giles's teampaper id: assigned by Dr. Jinseok Kimauthor list: names of authors in the byline of the paperyear: publication yearvenue: conference or journal namestitle: stopwords removed and stemmed by the Porter's stemmerIf you want to use this dataset, please consider to cite papers below.For the original dataset: Han, H., Giles, L., Zha, H., Li, C., & Tsioutsiouliklis, K. (2004). Two Supervised Learning Approaches for Name Disambiguation in Author Citations. JCDL 2004: Proceedings of the Fourth ACM/IEEE Joint Conference on Digital Libraries, 296-305. doi:10.1145/996350.996419For the filtered dataset: 1. Kim, Jinseok (2018). Evaluating author name disambiguation for digital libraries: a case of DBLP. Scientometrics. doi:10.1007/s11192-018-2824-5 or2. Kim, Jinseok & Kim, Jenna (2018). The impact of imbalanced training data on machine learning for author name disambiguation. Scientometrics. doi: 10.1007/s11192-018-2865-9</div
Characteristics in oxygen storage capacity of ceria-zirconia mixed oxides prepared by continuous hydrothermal synthesis in supercritical water
No full textContinuous hydrothermal synthesis in supercritical water (supercritical synthesis) is a method to prepare metal oxide nanoparticles rapidly and continuously using supercritical water. Highly crystallized nanoparticles of homogeneous complex metal oxides as well as single metal oxides Could be produced easily by the supercritical synthesis. Ceria-zirconia mixed oxide is widely used as oxygen storage material, for example, in the three-way catalysts for the clean LIP of automotive gases. Ceria-zirconia mixed oxides were prepared by the new supercritical synthesis method and also by the conventional co-precipitation method. The characteristics in oxygen storage capacity (OSC) of ceria-zirconia mixed oxide prepared by the supercritical synthesis were compared with those by the co-precipitation method. It was confirmed through physical characterizations with N-2 adsorption, SEM, TPR and O-2-uptake that the supercritical synthesis could lead to ceria-zirconia mixed oxides with higher thermal stability and better OSC due to its morphology. (c) 2006 Elsevier B.V. All rights reserved
Khoo Kay Kim, professor of Malaysian history : a biobibliometric study
Get PDFPresents an analysis of the publication productivity, authorship pattern, channels of communication, journal preference and language preference of Professor Dato' Khoo Kay Kim, Professor of Malaysian History in the University of Malaya, Kuala Lumpur. The results of this biobibliometric study indicate that he can be a role model for future Malaysian historians to emulate his various achievements especially in the field of history education
Anxious, Dismal, Giddy, Aggressive: Seth Kim-Cohen interviewed by Mark Peter Wright for Ear Room.
No full textA conversation with author Seth Kim-Cohen
Kim Gordon - no icon
No full textAs cofounder of legendary rock band Sonic Youth, best-selling author, and celebrated artist, Kim Gordon is one of the most singular and influential figures of the modern era. This personally curated scrapbook is an edgy and evocative portrait of Gordon s life, art, and style. Spanning from her childhood on Californian surf beaches in the 60s and 70s to New York s downtown art and music scene in the 80s and 90s where Sonic Youth was born. Through unpublished personal photographs, magazine and newspaper clippings, fashion editorials, and advertising campaigns, interspersed with Gordon s song lyrics, writings, artworks, private objects, and ephemera, this book demonstrates how Kim Gordon has been a role model for generations of women and me
Overview of Recent Progress in Fire Suppression
No full textthis document is published in / Une version de ce document se trouve dans : Invited Keynote Lecture at the 2 nd NRIFD Symposium, Proceedings, Tokyo, Japan, July 17-19, 2002, pp. 1-13 www.nrc.ca/irc/ircpubs NRCC-45690 Title: OVERVIEW OF RECENT PROGRESS IN FIRE SUPPRESSION TECHNOLOGY Author(s): Andrew KIM Corresponding (first) author: Andrew Kim Academic degree: Ph.
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