1,721,048 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Chemical and biological investigation of essential oil obtained from cultured Mentha spicata species
No full textAmaç: Tarihsel olarak bitkiler, insanoğlunun barınma, yakıt ve gıda ile ilgili ihtiyaçlarını karşılamak için hayati bir kaynak olarak kullanılmıştır. Bu çalışmada 2020-2022 yılları arasında kültüre alınmış Mentha spicata L. türünün hidrodistilayon yöntemiyle elde edilen uçucu yağının kimyasal bileşenlerinin, antiokisdan ve enzim inhibisyon aktivitelerinin belirlenmesi amaçlanmıştır. Gereç ve Yöntem: Çalışılan türün uçucu yağının kimyasal bileşenleri GC-MS tekniğiyle belirlenmiştir. Elde edilen uçucu yağın biyolojik aktivitelerini belirlemek için Serbest radikali giderim aktivitesi (DPPH), Katyon radikali giderim aktivitesi (ABTS) ve Bakır (II) iyonu indirgeme kapasitesi (CUPRAC) antioksidan test yöntemleri ve antikolinesteraz, anti-aging, üreaz ve tirozinaz enzin inhibisyon aktiviteleri kullanılmıştır. Bulgular: M. spicata türünün uçucu yağının yıllara göre (2020-22) GC-MS/FID sonuçlarına bakıldığında majör bileşenleri; karvon (sırasıyla; %46.92, %42.16 ve %48.77), limonen (%18.45, %16.99 ve %18.68) olarak tespit edilmiştir. M. spicata türlerinin uçucu yağının antioksidan ve asetilkolinesteraz ve üreaz enzim inhibisyon aktiviteleri göstermedikeleri belirlenmiştir. Çalışılan M. spicata türünün 2022 yılındaki uçucu yağlarının Bütirilkolinesteraz (BChE) ve elastaz test yöntemlerinde orta seviyede (sırasıyla, %inhibisyon: 31.50±0.54 ve 9.31±0.03) inhibisyon aktivite göstermiştir. Kollajenaz enzim inhibisyonunda ise M. spicata türünün 2021 yılında elde edilen uçucu yağının (%inhibisyon 14.48±0.16) orta sevide aktivite gösterdiği belirlenmiştir. Sonuç: Türlerin farklı yıllarda elde edilen uçucu yağ içerikleri değişmediği tespit edilmiştir ve bu anlamda bölgede türün uçucu yağı ile ilgili ekonomik potansiyelinin olduğu söylenebilir. M. spicata türünün çeşitli tıbbi özellikleri, gıda ve halk arasında kullanımları başta ilaç endüstrisi ve farmasötik preparatlarda kullanımı gittikçe önem kazanması ve M. spicata türüne olan ilgisinin artmasıyla çalışmalara konu olmuştur. Bu çerçevede tez sonuçların bu alana katkı sağlayacağı aşikârdır.Aim: Historically, plants have been used as a vital resource to meet human needs for shelter, fuel and food. In this study, it was aimed to determine the chemical constituents, antioxidant and enzyme inhibition activities of the essential oil obtained by hydrodistillation method of Mentha spicata L. species cultivated between 2020-2022. Material and Method: The chemical constituents of the essential oil of the studied species were determined by GC-MS technique. Free radical scavenging activity (DPPH), cation radical scavenging activity (ABTS) and copper (II) ion reducing capacity (CUPRAC) antioxidant test methods and anticholinesterase, anti-aging, urease and tyrosinase enzyme inhibition activities were used to determine the biological activities of the essential oil. Results: When the GC-MS/FID results of the essential oil of M. spicata species according to years (2020-22) were analyzed, the major components were determined as carvone (46.92%, 42.16% and 48.77%, respectively), limonene (18.45%, 16.99% and 18.68%). The essential oil of M. spicata species did not show antioxidant, acetylcholinesterase and urease enzyme inhibition activities. The essential oils of the studied M. spicata species in 2022 showed moderate (%inhibition: 31.50±0.54 and 9.31±0.03, respectively) inhibition activity in butyrylcholinesterase (BChE) and elastase test methods. In collagenase enzyme inhibition, it was determined that the essential oil of M. spicata species obtained in 2021 showed moderate activity (%inhibition 14.48±0.16). Conclusion: It was determined that the essential oil contents of the species obtained in different years did not change and in this sense, it can be said that there is an economic potential for the essential oil of the species in the region. Various medicinal properties of M. spicata species, its use in food and folk uses, especially its use in the pharmaceutical industry and pharmaceutical preparations have become increasingly important and have been the subject of studies with the increasing interest in M. spicata species. In this context, it is obvious that the results of this thesis will contribute to this field.Bu tez Dicle Üniversitesi Bilimsel Araştırma Projeleri Koordinatörlüğü (DÜBAP) tarafından ECZACILIK 20.003 nolu proje kapsamında desteklenmiştir
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
The determination of chemical and biological activites of some agricalturlly products medicinal and aromatic species
No full textAmaç: Bu çalışmada ülkemizin doğu bölgesinde doğal olarak yetişen bazı türlerin tarımsal kültürle çoğaltılan örneklerin (Sideritis libanotica subs kurdica, Thymus citriodorus, Origanum minutiflorum, Satureja macrantha, Lippia citriodora, Ziziphora clinopodioides, Cyclotrichium leucotrichum, Thymus vulgare, Nepeta italica, Origanum syriacum, Rosemarinus officinalis, Salvia palestina, Tanacetum parthenium, Melissa officinalis, Sideritis perfoliata, Origanum saccatum, Pelargonium graveolens, Salvia verticillata, Salvia multicaulis, Teucrium polium, Foeniculum vulgare, Pimpinella anisum, Mentha tomentosa, Thymbra spicata, Origanum onites, Origanum SP(Origanum onites+Origanum syriacum), Origanum vulgare subs. gracile) kimyasal ve biyolojik yönden detaylı araştırılması amaçlanmıştır. Gereç ve Yöntem: Bu çalışmada halk arasında daha çok kekik (Baharat) ve çay olarak kullanılan ve tarımsal kültür ile çoğaltılan 27 türün uçucu yağ (miktarı yeterli olan) ve etanol ekstreleri hazırlanarak elde edilen bu uçucu yağların ve etanol ekstrelerinin antioksidan (total fenolik, total flavonoit, DPPH, CUPRAC ve ABTS), antikolinesteraz (AChE ve BChE inhibitörleri), tirozinaz ve üreaz aktiviteleri belirlenmiştir. Ayrıca ekstrelerin toksik-sitotoksik etkileri MTT yöntemi ile belirlenmiştir. Miktarı yeterli olan türlerin uçucu yağı hidrodistilasyon yöntemi ile elde edilip bileşimi GC-MS/FID ile tespit edilmiştir. Ayrıca bu türlerin gıda olarak kullanılması nedeniyle GC-MS/FID SPME ile aroma içerikleri belirlenmiştir. Tüm türlerin etanol ekstreleri de hazırlanarak LC-MS/MS ile bu ekstrelerin fenolik içerikleri tespit edilmiştir. Bulgular: Tarımsal kültür ile çoğaltılan 27 türün aroma içeriği ve 13 türün uçucu yağ sonuçalarına göre majör bileşenler olarak karvakrol, timol, trans-geraniol, trans-sitral, pulegon, verbenon, linalil asetat, kafur, ?-pinen, sitronellol, limonen, anetol, 1,8 sineol, piperiton ve p-simen tespit edilmiştir. LC-MS/MS sonuçlarına göre ise genel olarak rosmarinik asit, astragalin ve luteolin 7-glikosid majör bileşen olarak belirlenmiştir. Antioksidan aktivite sonuçlarında, ABTS yönteminde Br-3,Br-10, Br-14, Br-15, Br-16, Br-24, Br-25, Br-27, Br-3 Ess, Br-8 Ess, Br-24 Ess, Br-25 Ess ve Br-27 Es (IC50: ?1 µg/mL) örneklerinin, DPPH yönteminde Br-14 (IC50: ?1 µg/mL) örneğinin oldukça yüksek aktivite gösterdiği ve standart bileşiklerden de daha aktif olduğu tespit edilmiştir. Türlerin etanol ekstrelerini asetilkolinesteraz enzim inhibisyon aktivitesine (AChE) bakıldığında Br-11 (%inhibisyon: 88.47±1.80), butirilkolinesteraz enzim inhibisyon aktivitesinde (BChE) ise Br-11 (%inhibisyon: 99.65±2.97) örneğinin en yüksek aktivite gösterdiği belirlenmiştir. Ayrıca Origanum cinsine ait tüm türlerin uçucu yağının antikolinestraz enzim aktivitelerinin hem AChE hem de BChE yönteminde oldukça aktif oldukları belirlenmiştir. Örnekler içerisinde Br-11 Ess örneğinin HT-29 kolon kanseri hücre serisine karşı en yüksek etkiyi (%Canlılık: 23.70±0.38), Br-24 Ess örneğinin MCF-7 hücre serisine karşı en yüksek etkiyi (%Canlılık: 11.20±0.14) gösterdiği belirlenmiştir. Sonuç: Ülkemizde yetişen 27 türün tarımsal kültür ile çoğaltılan örneklerin ekstreleri hazırlanmış ve incelenmiştir. Tüm örneklerin aroma içeriği belirlenirken miktarı yeterli olan türlerin uçucu yağı elde edilip içeriği aydınlatılmıştır. Elde edilen uçucu yağ ve etanol ektrelerinin kimyasal içerik analizlerinin yanısıra biyolojik özellikleride ortaya konularak sonuçlar bilim dünyasına kazandırılmıştır.Aim: In this study, some species grown naturally in the eastern region of our country (Sideritis libanotica subs kurdica, Thymus citriodorus, Origanum minutiflorum, Satureja macrantha, Lippia citriodora, Ziziphora clinopodioides, Cyclotrichium leucotrichum, Thymus vulgare, Nepeta italica, Origanum syriacum, Rosemarinus officinalis, Salvia palestina, Tanacetum parthenium, Melissa officinalis, Sideritis perfoliata, Origanum saccatum, Pelargonium graveolens, Salvia verticillata, Salvia multicaulis, Teucrium polium, Foeniculum vulgare, Pimpinella anisum, Mentha tomentosa, Thymbra spicata, Origanum onites, Origanum SP(Origanum onites+Origanum syriacum), Origanum vulgare subs. gracile) was aimed to be investigated in detail in terms of chemical and biological aspects. Material and Method: In this study, essential oils (sufficient amount) and ethanol extracts of 27 species, which are mostly used as oregano (spice) and tea and cultivated by agricultural culture, and ethanol extracts obtained by preparing antioxidant (total phenolic, total flavonoit, DPPH, CUPRAC and ABTS), anticholinesterase (AChE and BChE inhibitors), tyrosinase, urease activities were determined. In addition, the toxic-cytotoxic effects of the extracts were determined by MTT method. The essential oil of the species with sufficient amount was obtained by hydrodistilation method and its composition was determined by GC-MS/FID. In addition, since these species are used as food, aroma contents were determined by GC-MS / FID SPME. Ethanol extracts of all species were also prepared and the phenolic contents of these extracts were determined by LC-MS/MS. Results: According to the aroma content of 27 species propagated by agricultural culture and the essential oil results of 13 species, carvacrol, timol, trans-geraniol, trans-citral, pulegone, verbenone, linalyl acetate, camphor, ?-pinene, citronellol, limonene, anethole, 1,8-cineole, piperitone and p-cymene were determined as major components. According to LC-MS/MS results, in general rosmarinic acid, astragalin and luteolin 7-glycoside were determined as major components. In the antioxidant activity results, it was determined that the Br-3, Br-10, Br-14, Br-15, Br-16, Br-24, Br-25, Br-27, Br-3 Ess, Br-8 Ess, 24 Ess, Br-25 Ess and Br-27 Ess (IC50: ?1 µg / mL) samples in the ABTS method and the Br-14 (IC50: ?1 µg / mL) sample in the DPPH method showed quite high activity and were more active than the standard compounds. When the acetylcholinesterase enzyme inhibition activity (AChE) of the ethanol extracts of the species was examined, it was determined that Br-11 (inhibition%: 88.47 ± 1.80) and Br-11 (inhibition%: 99.65 ± 2.97) sample showed the highest activity in butyrylcholinesterase enzyme inhibition activity (BChE). In addition, it was determined that the anticholinestrase enzyme activities of the essential oil of all species belonging to the Origanum genus were quite active in both AChE and BChE methods. Among the samples, it was determined that Br-11 Ess sample had the highest effect (viability%: 23.70 ± 0.38) against HT-29 colon cancer cell line, and Br-24 Ess sample showed the highest effect (viability%: 11.20 ± 0.14) against MCF-7 cell line. Conclusion: The extracts of 27 species grown in our country with agricultural culture were prepared and examined. While determining the aroma content of all samples, the essential oil of the species with sufficient amount was obtained and the content was illuminated. In addition to the chemical content analysis of the essential oil and ethanol extracts obtained, their biological properties have been revealed and the results have been brought to the world of science.Dicle Üniversitesi Bilimsel Araştırma Projeleri Koordinatörlüğü (DÜBAP) tarafından Eczacılık.20.002 no'lu proje kapsamında desteklenmiştir
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