48,962 research outputs found

    Interview with YA mystery author, Valerie Sherrard

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    An interview with Valerie Sherrard, a YA author, which focuses on her process of writing the Shelby Belgarden mystery series.         

    2018-11-20 Chien-Hui Yang, DMA Solo Cello Recital

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    This recital is given in partial fulfillment of the requirements of the Doctor of Musical Arts degree. Chien-Hui is from the Studio of Prof. Dennis Parker

    Interview with YA author Vicki Grant

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    We feature an interview with Nova Scotian YA author Vicki Grant. Vicki is a prolific author who has written 14 books and has written over 100 episodes of children‘s TV. Vicki discusses her thoughts on reading positively and the meaning behind positivity, her favorite bad-day books, and how we as a community can promote reading positively. She makes us realize the importance of realism in writing and how important it is to connect with young readers

    Functional Polymorphism of Ctla-4 and Icos Genes in Allogeneic Hematopoietic Stem Cell Transplantation

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    T cells play a critical role in alloimmune recognition and thus contribute to graft-versus-host disease (GVHD) and relapse prevention in hematopoietic stem cell transplantation (HSCT). Cytotoxic T lymphocyte antigen-4 ( CTLA-4) and inducible costimulator (ICOS) are costimulatory molecules of T cell activation and their genetic variations can affect the capacity of T cells to become activated or inactivated. Methods: We examined CTLA-4 (-318 C/T and +49 A /G) and ICOS (c.602 A/C and c.1624 C/T ) genotypes in 123 patients with HSCT and their HLA-matched sibling donors , and then evaluated the impacts of the genetic polymorphisms on GVHD, disease relapse, and survival. Results: By multivariate analysis, the donor CTLA-4 - 318 TT genotype increased the risk of disease relapse ( Hazard ratio [HR]: 5. 91, 95% confidence interval [CI]: 1.17-29.79, P=0. 0313). Recipients who received a graft from a donor with ICOS c.602 CC genotype had worse disease-free survival (HR: 5.97, 95% CI: 1.49-23.87, P= 0.0115). Additionally, recipients with ICOS c.1624 TT genotype had worse overall survival (HR: 12. 98. 95% Cl: 2.58-65.35, P=0.0019). Nevertheless, CTLA-4 and ICOS genotypes were not associated with acute and chronic GVHD . Conclusions: Both donor and recipient CTLA-4 and ICOS gene polymorphisms might be of importance for the outcome of allogeneic HSCT

    Interview with YA author and Children‘s Editorial Assistant Suzanne Sutherland

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    An interview with Young Adult author Suzanne Sutherland. The interview focuses on Toronto, the straight edge scene, music and subculture, Sutherland\u27s first book, When We Were Good and the importance of queer representation in YA books. Sutherland also recommends a number of YA novels

    A Study of Chien Tseng\ue2s Poetry in The Early Qing Empire\uef\ubcContemplative\ue3Extraordinary and Adherents Writing

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    In The Early Qing Empire , Chien Tseng(1629-1701) is famous for collect books , he is important to Bibliography today . At the same time , Chien Tseng was a poet , he wrote as a focus as poetry of the adherents , while showing contemplative and extraordinary two kinds of art , as well as the integration of many artistic skills and styles . In this paper , the study of Chien Tseng\ue2s poetry , focusing on poetry content , poetry art and poetry realm . This paper is divided into seven chapters , the first chapter is introduction , including the research motive and research method ; the second chapter explains the background of the times , including the historical background , social background and literary background ; the third chapter analyzes the poem content , understanding the subject matter of Chien Tseng\ue2s description of the subject matter , master the poet\ue2s creative core ; the fourth chapter analyzes the image representation of poems and understands the use of image ; the fifth chapter discusses the writing skills of poems and understands the art of poetry ; the sixth chapter analyzes the artistic conception of poetry ; the seventh chapter is conclusion

    Evaluating the Collaborative Ecosystem for an Innovation-Driven Economy: A Systems Analysis and Case Study of Science Parks

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    National policies for science parks and innovation have been identified as one of the major driving forces for the innovation-driven economy, especially for publicly funded science parks. To investigate this collaborative ecosystem (government-academia-industry) for growth and sustainable development, this paper proposes a nation-wide economic impact analysis of science parks and innovation policy based on historical data drawn from one of the globally recognized high-technology industrial clusters in Taiwan. Systems thinking with causal loop analysis are adopted to improve our understanding of the collaborative ecosystem with science park policies. First, from a holistic viewpoint, the role of government in a science parks and innovation ecosystem is reviewed. A systems analysis of an innovation-driven economy with a science park policy is presented as a strategy map for policy implementers. Second, the added economic value and employment of the benchmarked science parks is evaluated from a long range perspective. Third, the concepts of government-academia-industry collaboration and policies to innovation ecosystem are introduced while addressing the measures and performance of innovation and applied R&D in the science parks. We conclude with a discussion of lessons learned and the policy implications of science park development and an innovation ecosystem
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