150,603 research outputs found
KRITIK SOSIAL DALAM NOVEL F? SAB?L AL- T?J KARYAMUST>{?F?LUT{FY AL-MANFAL??Y(SUATU TINJAUAN INTRINSIK)
No full textABSTRAKSkripsi ini berjudul kritik sosial dalam novel F? Sab?l Al- T?j karyaMusthafa lutfy Al-manfaluty (Suatu Tinjauan Intrinsik). Skripsi ini membahastentang kritik sosial yang terdapat dalam novel F? Sab?l Al- T?j. Tujuan penelitianuntuk menjelaskan kritik sosial dan bentuknya dalam novel F? Sab?l Al- T?j .Metode penelitian yang digunakan adalah kepustakaan (library research).Populasi dalam penelitian ini adalah novel F? Sab?l Al- T?j dan terjemahannyaDemi Mahkota untuk artinya, Sedangkan sampel penelitian ini adalah kritiksosisal dalam novel F? Sab?l Al- T?j .Hasil penelitian menunjukkan bahwa kritik sosial dalam F? Sab?l Al- T?jadalah kritik terhadap pemerintah, kekuasaan, prekonomian, dan hak asasimanusia. Sedangkan bentuk kritik sosial berupa langsung dan tidak langsung.xv + 60 hlm
DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire
No full textThe majority of known human tumor-associated antigens derive from non-mutated self proteins. T cell tolerance, essential to prevent autoimmunity, must therefore be cautiously circumvented to generate cytotoxic T cell responses against these targets. Our strategy uses DNA fusion vaccines to activate high levels of peptide-specific CTL. Key foreign sequences from tetanus toxin activate tolerance-breaking CD4+ T cell help. Candidate MHC class Ibinding tumor peptide sequences are fused to the C terminus for optimal processing and presentation. To model performance against a leukemia-associated antigen in a tolerized setting, we constructed a fusion vaccine encoding an immunodominant CTL epitopederived from Friend murine leukemia virus gag protein (FMuLVgag) and vaccinated tolerant FMuLVgag-transgenic (gag-Tg) mice. Vaccination with the construct induced epitopespecificIFN-c-producing CD8+ T cells in normal and gag-Tg mice. The frequency and avidity of activated cells were reduced in gag-Tg mice, and no autoimmune injury resulted. However, these CD8+ T cells did exhibit gag-specific cytotoxicity in vitro and in vivo. Also, epitope-specific CTL killed FBL-3 leukemia cells expressing endogenous FMuLVgag antigen and protected against leukemia challenge in vivo. These results demonstrate a simple strategy to engage anti-microbial T cell help to activate epitope-specific polyclonal CD8+ T cell responses from a residual tolerized repertoire
L1-stability estimates for n x n conservation laws
No full textLet u(t) + f (u)(x) = 0 be a strictly hyperbolic n x n system of conservation laws, each characteristic field being linearly degenerate or genuinely :nonlinear. In this paper Mie explicitly define a functional Phi = Phi (u, upsilon,), equivalent to the L-1 distance, which is "almost decreasing" i.e.,
Phi(u (t), upsilon (t)) - Phi(u (s), upsilon (s)) less than or equal to O (epsilon) . (t - s) for all t > s greater than or equal to 0, for every pair of epsilon-approximate solutions u, upsilon with small total variation, generated by a wave front tracking algorithm. The small parameter epsilon here controls he errors in the wave speeds, the maximum size of rarefaction fronts and the total strength of all nonphysical waves in u and in upsilon. From the above estimate, it follows that front-tracking approximations converge to a unique limit solution, depending Lipschitz continuously on the initial data, in the L-1 norm. This provides-a new proof of the existence of the standard Riemann semigroup generated by a n: x n system of conservation laws
Letter from Carl Hayden to Henry F. Ashurst
No full textLetter describing three enclosures, a letter from F. M. Gold, Carl T. Hayden's reply to Gold's letter, and a copy of a bill introduced by Cameron
Letter from A. F. Potter to Carl Hayden
No full textLetter from A. F. Potter to Carl T. Hayden describing John H. Page's request to build a railway for the Canyon Copper Company as "impractical"
Capacity and Error Performance of Reduced-Rank Transmitter Multiuser Preprocessing Based on Minimum Power Distortionless Response
No full textIn this contribution we first derive a transmitter multiuser preprocessing (TMP) scheme for a general multiuser multiple-input-multiple-output (MIMO) system based on the minimum power distortionless response (MPDR) criterion, which minimizes the power in the context of a given downlink mobile terminal (MT) under the distortionless condition. This optimization problem results in a solution, which has the same form as the minimum mean-square error (MMSE) multiuser detection (MUD). Hence, we then extend the well-known rank-reduction techniques in MMSE-MUD to the MPDR-TMP in order to mitigate the possible implementation problems of the MPDRTMP. In our study three classes of rank-reduction algorithms are considered, which are derived, respectively, based on the eigen-analysis methods of principal components (PC) and crossspectral metrics (CSMs) as well as on the Taylor polynomial approximation (TPA) approach, which does not depend on the eigen-analysis. In this contribution both the capacity and error performance of a downlink space-division multiple-access (SDMA) system is investigated, when either the full-rank or reduced-rank MPDR-TMP is invoked. From our study and simulation results, it can be shown that the MPDR-TMP scheme is highly efficient for achieving the capacity and for suppressing the multiuser interference (MUI). The reduced-rank techniques can be employed by the MPDR-TMP, so as to reduce its implementation complexity while achieving the near full-rank performance of the full-rank MPDR-TMP
Conformal transformation in f(T) theories
No full textIt is well known that f(R) theories are dynamically equivalent to a particular class of scalar-tensor theories. In analogy to the f(R) extension of the Einstein-Hilbert action of general relativity, f(T) theories are generalizations of the action of teleparallel gravity. The field equations are always second order, remarkably simpler than f(R) theories. It is interesting to investigate whether f(T) theories have the similar conformal features possessed in f(R) theories. It is shown, however, that f(T) theories are not dynamically equivalent to teleparallel action plus a scalar field via conformal transformation, since there appears an additional scalar-torsion coupling term. We discuss briefly what constraint of this coupling term may be put on f(T) theories from observations of the solar system
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
Full text linkIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
New types of f(T) gravity
No full textRecently f(T) theories based on modifications of teleparallel gravity, where torsion is the geometric object describing gravity instead of curvature, have been proposed to explain the present cosmic accelerating expansion. The field equations are always second order, remarkably simpler than f(R) theories. In analogy to the f(R) theory, we consider here three types of f(T) gravity, and find that all of them can give rise to cosmic acceleration with interesting features, respectively
On F-injectors of fitting set of a finite group
No full textYang, N. On F-injectors of fitting set of a finite group / Nanying Yang, W. Guo, N. T. Vorob’ev // Communications in Algebra. – 2018. – Vol. 46, № 1. – P. 217–229.Let G be some generalized π-soluble groups and F be a Fitting set of G. In this paper, we prove the
existence and conjugacy of F-injectors of G and give a f the structure of the injectors
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