47,251 research outputs found
Dynamics of gene expression profiling in liver following thermal injury and sepsis
No full textBurn injury leads to a prolonged inflammatory response in the body. Moreover, severe burn injuries are always associated with bacterial infections which cause more persistent inflammatory response, resulting in prolonged hyper-metabolism and hyper-catabolism on systemic level. Despite significant advances in patient care, morbidity and mortality remain high in those patients. The difficulty in developing new and more effective medications is due, in part, to our incomplete understanding of the underlying pathophysiology of the disease. Liver, the main organ regulating both the inflammation and metabolism plays a key role in responding to external injuries. Thus, analyzing the responses in liver to burn, infection and “double hits” injury from global perspective as well as in a timely manner may offer a molecular framework for study on the pathophysiology of systemic inflammation induced by injuries. The overall studies were divided into single injury in which the animals were subjected to single burn injury or single cecal ligation and puncture (CLP) injury individually and “double hits” injury in which the rats were subjected to a burn injury and subsequent CLP injury. Animals were sacrificed at various time points, and whole liver samples were analyzed using Affymetrix Rat Genome 230 2.0 Arrays. After identifying differentially expressed probesets in injury rats vs. sham over time, the concatenated data sets corresponding to these differentially expressed probesets in injury and sham were combined and analyzed using a “consensus clustering” approaches. Ingenuity Pathway Analysis (IPA) was used to functionally annotate genes, and RT-PCR was used to confirm microarray trends. Both single burn and CLP injury induces the activation of pro-inflammatory response, anti-inflammatory response, and enhanced synthesis of acute-phase proteins, increased metabolism and tissue damage. Genes which are directly in response to bacteria removal are only triggered in CLP injury. In double hits study, burn priming prior to CLP disrupts the transcriptional response in the liver to septic injury in the rat by altering the onset of anti-bacterial functions in the liver. In addition, burn enhanced hyper metabolic conditions through aggressive amino acid degradation at critical time points.Ph. D.Includes bibliographical referencesby Qian Yan
Qian dao comic
No full textQian Dao Comic merupakan sebuah rancangan usaha untuk menerbitkan sebuah komik-komik yang menggunakan dwi-bahasa, yaitu bahasa Mandarin sebagai bahasa utama dan bahasa Indonesia sebagai bahasa pendukung. Komikkomik tersebut akan disadur dari penerbit-penerbit yang ada di dalam maupun di luar negeri, yang mana cerita-cerita yang disadur tersebut dikhususkan pada cerita dongeng, legenda, mitos, dan cerita rakyat. Penyalur yang digunakan oleh Qian Dao Comic ada 3, yaitu kursus bahasa Mandarin, toko buku, dan agen. Untuk membangun bisnis ini diperlukan dana atau investasi sebesar Rp.900.000.000,00 yang mana diperkirakan dalam waktu 18 bulan, perusahaan tela h mencapai payback period
Mesonemoura longiflagellata Xiao & Zhao & Qian & Du 2019, sp. nov.
No full textMesonemoura longiflagellata Xiao & Qian sp. nov. Figs. 1–10 Adult habitus. General color dark brown. Head dark brown to black, antennae dark brown, palpi brown. Thorax dark brown, pronotum trapezoid, wider than long, rugosities scattered. Legs dark brown, femora and tibiae with a yellowish band. Wings light brown, veins dark brown. Abdomen brown, terminal segments dark brown (Fig. 1). Male terminalia. Terga 1–7 sclerotized of the anterior area. Tergite 8 anteriorly sclerotized. Sterna 1–8 mostly membranous, laterally sometimes speckled. Tergite 9 sclerotized laterally and anteriorly, medially membranous, tiny bristles at the junction of the membranous and sclerotized area (Figs. 2, 6). Hypoproct of sternite 9 broad basally, abruptly tapering toward the apex, apically blunt; vesicle elliptical and slender, medially membranous (Fig. 3). Tergite 10 strongly sclerotized, medially membranous with sparse tiny bristles laterally of membranous area anteriorly of tergite 10 (Figs. 2, 5 6, 8). Epiproct slender, basally and marginally sclerotized, median portion membranous. Flagellum dark brown, long and broad basally, tapering slightly towards the apex, curved in dorsal view, tip blunt and membranous in dorsal and lateral view (Figs. 2, 5, 6, 7). Paraproct with 3 lobes: inner lobe sclerotized, apex bifurcate and pointed of the same length; median lobe consists of two parts, inside portion strongly sclerotized with tip with a row of tiny spines, outside portion membranous, shorter than inside portion and with many hairs, connected with outer lobe; outer lobe slender, entirely sclerotized, basal recurved along the cerci, tip blunt. (Figs. 3, 9). Cerci cylindrical, bearing many hairs, slightly bent inwards (Figs. 2, 3, 5, 6). Female terminalia. Pregenital plate on sternite 7 appears as an inverted triangle, posteriorly reaching anterior margin of sternite 8. Sternite 8 with sclerotized subgenital plate, semicircular and deeply indented in the middle. A pair of symmetrical arc-shaped lateral sclerites, a part under the middle of subgenital plate, and the other part stretches out the subgenital plate and reach the posterior margin of sternite 8. Sternite 9 sclerotized posteriorly and medially with indented membranous area. (Fig. 4, 10). Material examined. Holotype male, CHINA: Yunnan Province, Shangri-la City, Pudacuo National Park, 27°52’17” N, 99°54’26” E, 3879 m, 11 September 2017, Leg. Qian Xiao, Yu-Han Qian, Jia-Hao Chen. Paratypes: 3 males and 5 females, same data as holotype (ICSFU). 3 males and 2 females, CHINA: Yunnan Province, Shangrila City, Baima Snow Mountain Nature Reserve, 28°18’33” N, 99°8’9” E, 3514 m, 18 July 2017, Leg. Yu-Han Qian, Qian Xiao, Ming-Xue Xie, Jia-Hao Chen, Jin-Long Wei. Etymology. The Latin name “ longiflagellata ” means with a long flagellum, referring to the distinctly long flagellum of the epiproct. Remarks. The new species is apparently closely related to M. sbordonii Fochetti & Sezzi, 2000 from Yunnan Province of China, M. spiroflagellata (Wu, 1973) and M. sichuanensis Du & Ji, 2015 from Sichuan Province of China, M. tritaenia Li & Yang, 2007 from Henan Province of China. The male and female of M. longiflagellata can be distinguished from the M. sbordonii by the long flagellum without a forked tip and the pregenital plate of female not reaching sternite 9, and the semicircular subgenital plate with a pair of symmetrical arc-shaped lateral sclerites. Additionally, the male paraproct and the female pregenital plate of the new species differ from M. spiroflagellata and M. tritaenia. Mesonemoura longiflagellata also has a row of tiny spines on the tip of the median lobe of paraproct differing from M. sichuanensis.Published as part of Xiao, Qian, Zhao, Jing, Qian, Yu-Han & Du, Yu-Zhou, 2019, Two new species of Mesonemoura (Plecoptera: Nemouridae) from Yunnan Province of China, pp. 531-538 in Zootaxa 4565 (4) on pages 531-533, DOI: 10.11646/zootaxa.4565.4.7, http://zenodo.org/record/259135
Glimmer before sunrise: Qian Song (1818-1860) and his elite art in nineteenth-century China
No full textThis thesis offers the first comprehensive and in-depth study of Qian Song 錢松
(1818-1860), an intellectual artist from the late Qing Dynasty. Qian Song’s role and the
era he lived in were both unique. He was a member of the famous group of seal carving
artists known as the Eight Masters of Seal Carving in Hangzhou. However, due to his
versatile seal carving style, which differed significantly from the other seven masters,
debates about the reasonability of his identity have never ceased. The development of
jinshixue ⾦⽯學 (bronze and stone scholarship) from the late 18th century to the early
19th century directly led to artistic trends in calligraphy, painting, and seal carving in
the late 19th century. Qian Song’s active period was during the mid-19th century,
specifically 1840-1860, which was at the peak of domestic upheavals and external wars,
and this period also marked a turning point for the Chinese elite art.
The research conducts the study through several dimensions, including Qian Song’s
social interactions with the intellectual artists in the Jiangnan area, the developmental
context of bronze and stone prior to 1840, the lineage of Eight Masters of Seal Carving
in Hangzhou, Qian Song’s seal carving and calligraphy. By exploring these aspects in
the study of Qian Song, we aim to understand the artistic pursuits, achievements, and
social life of an outstanding literati artist renowned for his seal carving during the
transitional period of early 19th century antiquarian study.
After the Introduction of the literature review and the approaches, Chapter Two
investigates Qian Song’s social interactions, providing a clearer understanding of his
life through his social engagements in Hangzhou and Shanghai and analysing how he,
as an intellectual artist, established his social network via his artistic creation in a time
of turmoil. This chapter also serves as part of Qian Song’s biography. The third chapter
focuses on the transition of the main function of bronze and stone scholarship from
academic research to inspiration for artistic creation from the late 18th century to the
early 19th century. This period serves as the background and foundation for Qian Song’s
artistic style. In Chapter Four, I will delve into the development model of the Eight
Masters of Seal Carving in Hangzhou, which is the base of Qian Song’s artistic taste
and method. My study explores the cultural and artistic activities of these eight masters
individually. The last two chapters respectively examine Qian Song’s seal carving and
calligraphy, analysing his artistic styles
Rhopalopsole triseriata Qian & Du, sp. nov.
No full textRhopalopsole triseriata Qian & Du, sp. nov. Figs. 4–6. Material examined. Holotype male, Sichuan Province, Luding County, Hailuogou, 2200m, 3 Jul. 2009, Leg. Qian Yu-han. Paratype male, Tibet, Motuo County, Beibeng, 780m, 17 Jun. 2009, Leg. Qian Yu-han. Adult habitus. Head dark brown, wider than pronotum; hind ocelli much closer to the eyes than to each other, antennae and palpi dark brown. Pronotum dark brown, subquadrate, all angles somewhat rounded with black irregular stripes on surface. Legs dark brown. Wings hyaline, veins light grayish brown. Male. Approximate measurement: forewing length 5.0mm, body length 5.5mm. Tergum 9 weakly sclerotized, distinctly wider than long, posterior margin with two narrow, distinctly sclerotized transverse bands; transverse bands more or less connected in the middle, and expand on each side (Fig 4). Sternum 9 subgenital plate wider than long and rounded apically; basally, tongue shaped vesicle bears dense hairs (Fig 5). Tergum 10 with strongly sclerotized lateral process rather thick basally, thin apically and ending a sharp point in lateral view (Fig 6); midanterior sclerite sclerotized, distinctly wider than long, bearing two short obtuse lateral processes and one slightly longer middle process with expanded tip; tergum also bearing weakly sclerotized mid-posterior transverse sclerites (Fig 4). Epiproct simple curved process with erect spine-line apical portion (Fig 1). Subanal lobes long and upturned, in ventral aspect, two sides of subanal lobes folded inward, narrow basally and expanded apically, distinct longitudinal furrows cover the dorsal and ventral surface (Fig 5). Cerci cylindrical and bent upward without a tiny apical spine (Fig 6). Female. Unknown. Distribution. Sichuan Province, Xizang (= Tibet) Autonomous Region. Etymology. Latin “ tri ” means three; Latin “ seriata ” means row. The species name refers to the shape of the mid-anterior sclerite of tergum 10. Diagnosis. Rhopalopsole triseriata is a member of the R. magnicerca group (Sivec et al. 2008, Stark et al. 2012, Li and Yang 2012), which currently includes 14 species, six of these known from China (Li and Yang 2012). Males of the group are generally recognized by the moderately long, relatively stout posterolateral projections of tergum 10 and by a pair of sublateral raised areas on the posteromedian margin of tergum 9. The epiproct of the known species are small, hook-like projections and the cerci are upturned and lack terminal spines. Rhopalopsole triseriata appears distinct from the known members of this group in shape of the mesal sclerite, lateral process, and subanal lobe of tergum 10. In R. bispina (Wu, 1949), also known from Sichuan Province, this structure is broadly cordate in shape with only a weak suggestion of three lobes and lateral projections gradually and regularly tapering ending in a sharp (Sivec et al. 2008), whereas in R. longispina, Yang & Yang (Yang & Yang 1991 b) and R. emeishan Sivec & Harper (Sivec et al. 2008), the three lobes of the sclerite are quite distinct, but in R. longispina, two sides of subanal lobes not fold inward. The shape of mesal sclerite and subanal lobes allies the new species most closely with R. emeishan Sivec & Harper, 2008, because both have the median lobe bearing an expanded tip on a slender stalk, and in addition the subanal lobes are similar in ventral aspect. However, the lateral aspects of the processes of tergum 10 are quite different. In R. emeishan, a basal notch is present and lateral margins of the thinner process are parallel for most of its length, whereas in R. triseriata the basal notch is lacking and the thicker process has more rounded margins in the basal half. The recent key to the Chinese species of R. magnicerca group by Li & Yang (2012) can be modified to include R. triseriata as follows: 1. Lateral projections of tergum 10 nearly parallel–sided in lateral view............................................. 2 –. Lateral projections of tergum 10 gradually tapering toward apex in lateral view.................................... 3 2. Male subanal lobe basally with well-defined sloping furrows, female subgenital plate only slightly produced, darkened areas triangular......................................................................... R. lewolong Li and Yang –. Male subanal lobe basally with lateral margins smooth flap and apically with longitudinal furrows, female subgenital plate pro- duced into triangular apical extension, darkened areas irregular.......................... R. emeishan Sivec and Harper 3. Lateral projections of tergum 10 downcast medially in lateral view, subanal lobes with furrow area bulging and bulbous................................................................................... R. minutospina Li and Yang –. Lateral projections of tergum 10 curved upward in lateral view, subanal lobes with furrow area concave or lacking distinct fur- row................................................................................................. 4 4. Lateral projections of tergum 10 with long and narrow in dorsal view, distal half gradually tapering into a sharp point...... 5 –. Lateral projections of tergum 10 relatively robust in dorsal view, apex with an abruptly sharpened point................. 6 5. Subanal lobes lacking a distinct furrow................................................. R. xui Yang, Li, and Zhu –. Subanal lobes with a distinct furrow, folded inward......................................... R. triseriata Qian & Du. 6. Lower base of the lateral projections with a distinct indentation in males, female subgenital plate with a broad extension, trans- verse bar of sternum 8 entire................................................................. R. bispina (Wu) –. Lower base of the lateral projections lacks an indentation in males, female subgenital plate with a narrower triangular exten- sion, transverse bar of sternum 8 split into two triangular lobes by medial membrane.......... R. longispina Yang and YangPublished as part of Qian, Yu-Han & Du, Yu-Zhou, 2013, Two new species of Rhopalopsole (Plecoptera: Leuctridae) from China, pp. 588-592 in Zootaxa 3599 (6) on pages 590-591, DOI: 10.11646/zootaxa.3599.6.7, http://zenodo.org/record/22425
Zhongguo weishenme shuo bu?, de Peng Qian, Yang Mingjie, Xu Deren
No full textBéja Jean-Philippe. Zhongguo weishenme shuo bu?, de Peng Qian, Yang Mingjie, Xu Deren. In: Perspectives chinoises, n°37, 1996. p. 68
Zhongguo weishenme shuo bu?, de Peng Qian, Yang Mingjie, Xu Deren
No full textBéja Jean-Philippe. Zhongguo weishenme shuo bu?, de Peng Qian, Yang Mingjie, Xu Deren. In: Perspectives chinoises, n°37, 1996. p. 68
- …
