5,762 research outputs found

    Letter from Cy Donner to Michi Weglyn, June 2, 1967

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    A letter from Cy Donner to Michi Weglyn encouraging her to come out to California to talk to producers about two shows called "Youthquake" and "Pretty Talk".These materials are from box 73 and 74 of the Frank Chin Papers. The Frank Chin Papers contain personal and professional correspondence between Frank Chin and Michi Weglyn relating to particular projects on which either author was working as well as files related to the Day of Remembrance Tribute to Michi Weglyn

    A study of void crushing in large forgings II. Estimation of bonding efficiency by finite-element analysis

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    Larger ingots are required in the steel industry because the major parts of many products are needed as one large body in order to obtain higher quality. In large ingots, internal voids have to be eliminated so as to obtain sound products. Void crushing is carried out in at least two steps, i.e. void closing and hot pressure bonding. This study is concerned with hot pressure bonding of internal voids, the objective of the study being to estimate the bonding efficiency by the finite-element method and using the estimation method proposed in a previous paper. From the thermo-viscoplastic finite-element method, a boundary condition was imposed on the surface of an internal void. Experiments were also carried out in order to compare the bonding efficiency with that of the proposed modelling, in which the required data were obtained from the finite-element analysis. The results calculated using the proposed model are in good agreement with the experimental results. According to the variation of the position of the void and the change of die shape, the bonding efficiency is estimated and the height reduction of forging for the elimination of the voids is correctly estimated through analysis of the bonding process. (C) 1997 Elsevier Science S.A

    Modelling of void crushing for large-ingot hot forging

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    The present work is concerned with the elimination of internal voids in a large ingot so as to obtain defect-free products. The void-crushing process is analyzed by the thermo-viscoplastic finite-element method for three-dimensional forging at elevated temperature. The effects of the pre-cooling temperature, the rate of deformation and the change of the die-shape are discussed for obtaining the high crushing efficiency of a void, using the Taguchi method. The bonding efficiency is also estimated and the optimal combination of forging parameters for the elimination of Voids is determined using the Taguchi method, in which a new objective function has been used considering load constraint. (C) 1997 Elsevier Science S.A

    Outcome of medium-dose VP-16/CY/TBI superior to CY/TBI as a conditioning regimen for allogeneic stem cell transplantation in adult patients with acute lymphoblastic leukemia

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    The choice of conditioning regimen before allogeneic stem cell transplantation (SCT) in patients with acute lymphoblastic leukemia (ALL) is important. We retrospectively compared outcomes of medium-dose VP-16/cyclophosphamide/total body irradiation (VP/CY/TBI) regimen and CY/TBI. Five hundred and twenty-nine patients (VP/CY/TBI: n = 35, CY/TBI: n = 494) who met all of the following criteria were compared: first time for SCT, aged 15-59 years; first or second complete remission at SCT; bone marrow or peripheral blood as stem cell source; and HLA phenotypically matched donor. Median age of the patients was 34 years, and patients who received VP/CY/TBI were younger (28 years vs. 34 years, P = 0.02). Cumulative incidences of relapse and non-relapse mortality (NRM) were higher for patients who received CY/TBI (P = 0.01 for relapse, P < 0.01 for NRM). After a median follow-up period of 36.9 months, 5-year overall survival (OS) rates were 82.2% in the VP/CY/TBI group and 55.2% in the CY/TBI group. OS, and disease-free survival (DFS) in the VP/CY/TBI group were shown to be significantly better by multivariate analysis [hazard ratio: 0.21 (95% confidence interval: 0.06-0.49) for DFS, hazard ratio: 0.25 (95% confidence interval: 0.08-0.59) for OS]. VP/CY/TBI was associated with a lower relapse rate and no increase in NRM, resulting in better survival than that in CY/TBI for adult ALL patients
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