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    Heat shock transcription factor A6b, AtHSFA6b, is induced through ABA-dependent signaling and mediates several abiotic stress responses in Arabidopsis thaliana

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    植物在生長發育的過程中可能會遭受到許多逆境,包括溫度、鹽分以及水分逆境等。而熱休克反應是植物對抗熱逆境的重要機制之一,過程中藉由熱休克轉錄因子調控熱休克蛋白質的產生來保護細胞,以降低熱逆境的損害。分析微陣列晶片中的資料,顯示阿拉伯芥的熱休克轉錄因子會被多種生物性或非生物性逆境所誘導,其中在熱休克轉錄因子A6群中之AtHSFA6a會被滲透逆境所誘導,AtHSFA6b則主要會被冷、鹽分、滲透以及乾旱逆境誘導;此外,兩者皆會被離層酸誘導表現。顯示這兩者可能會參與在離層酸所調控的逆境反應當中。在本篇文章中,我們利用遺傳及分子層次的分析來調查阿拉伯芥AtHSFA6中之兩個成員在遭遇逆境時所扮演的角色。首先,我們確定了兩者皆會受離層酸、鹽與滲透逆境所誘導;在離層酸缺失及對離層酸不敏感的突變株中,證實離層酸相關的訊號傳遞對於AHSFA6b的表現是必須的;同時AHSFA6b啟動子中之離層酸反應序列(ABRE)對其感應ABA是不可或缺的,以上結果顯示AtHSFA6b參與在離層酸相關的訊號路徑之中。藉由觀察突變株和轉植株在子葉綠化、根系生長以及其對鹽分耐受性的差異,結果顯示AtHSFA6b確實參與在離層酸所調控的非生物逆境反應當中;此外,耐熱性的測試結果也顯示AtHSFA6b同樣也參與在先天耐熱性及誘導耐熱性的調控過程之中。我們的研究結果說明了,AtHSFA6b除了在複雜的熱休克轉錄因子調控網絡當中扮演重要角色外;另外加入了一條新的調控路徑,那就是在離層酸所調控的非生物性逆境反應中也扮演著正向的調控因子。Plants face various environmental stresses, such as drought, salinity, heat and cold directly. In response to heat stress (HS), heat shock response (HSR) is a conserved mechanism of increasing heat shock protein (HSP) genes expression through a heat shock factors (HSFs)-dependent mechanism. According to microarray databases, AtHSFA6a is induced by salt and osmotic stress, while AtHSFA6b expression is responsive to cold, salt, osmotic and drought treatment; in addition both genes are upregulated by ABA treatment suggesting the AtHSFA6s may involve in ABA-mediated responses. This report describes our investigation of the role of AtHSFA6s in response to abiotic stress in Arabidopsis by genetic and molecular approaches. Both AtHSFA6s were induced by abscisic acid (ABA), salt and osmotic stress. Downregulated AtHSFA6b expression in ABA-deficient and ABA-insensitive mutants indicates that ABA signaling is required for AtHSFA6b expression. Notably, ABRE acts as the functional cis-element in the promoter region of AtHSFA6b, suggests AtHSFA6b is a member involved in ABA-dependent pathway. Analysis of cotyledon greening, root growth and salt tolerance in mutant lines and transgenic plants indicated that AtHSFA6b participates in ABA-mediated stress responses and acts as a positive regulator. In addition, thermotolerance tests also showed AtHSFA6b is involved in basal- and acquired-thermotolerance. These studies reveal AtHSFA6b is a positive regulator in ABA-mediated stresses, and add a new signaling pathway into the complex HSF network

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used

    Author Under Sail The Imagination of Jack London, 1893-1902

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    In Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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