997 research outputs found

    xM state cells are involved in vasculogenic mimicry (VM).

    No full text
    (A) Tumors formed by E, E/M, and xM cells were analyzed by H&E staining and IHC analysis for the CD34 (Brown) and PAS (Purple). Pink arrows indicate VM channels (PAS+/CD34-), brown arrows indicate classic angiogenesis (PAS+/CD34+), which is included as a control. Quantification of VM channels determined by microscopy with 400x magnification in randomly chosen fields (n = 3 per group, ** PB) NPC clinical samples were analyzed by IHC analysis for detecting VM channels, three representative areas in one case are shown. (C) The colocalization of ZEB1 (Brown) and PAS (Purple) in xM tumor, as well as NPC clinical sample (D). Images of three representative areas in one tumor sample are shown. (E) Vasculogenic mimicry of E, E/M, and xM cells was analyzed by Matrigel tube formation assay in vitro (Mean +/- SD of three biological replicates, *** P<0.001).</p

    Effects of silencing LMP1 and LMP2A expression on plasticity of E/M and xM cells.

    No full text
    (A) Purified E/M cells were transfected with siRNAs to knock down the expression of LMP1 or LMP2A. The knockdown efficiencies of these siRNAs in E/M cells were analyzed by Western blot. (B) The changes of CD44 and CD104 profile in E/M cells were analyzed by flow cytometry analysis. (C) Purified xM cells were transfected with siRNAs to knock down the expression of LMP1 or LMP2A. The knockdown efficiencies of these siRNAs in xM cells were analyzed by Western blot. (D) The changes of CD44 and CD104 profile in xM cells were analyzed by flow cytometry analysis. (TIF)</p

    Research on the Improvement of Cargo Service Quality of XM Airlines

    No full text
    This study takes XM Airlines' baggage check-in service as the object, and based on the SERVQUAL model and analytic hierarchy process, constructs a service quality evaluation system to systematically evaluate its service status. The main content includes the following: Firstly, based on the theoretical framework, a basic overview and analysis of the operational status of XM Airlines are conducted to understand the main problems currently existing, and a targeted evaluation system is constructed for the existing problems. Secondly, based on the completed evaluation system, the Analytic Hierarchy Process is used to establish a corresponding mathematical model. The systematic problem of evaluating the quality of freight services is decomposed into various factors for quantitative analysis, and the importance weights of each factor are calculated and ranked. Thirdly, analyze and summarize the analysis data of the second stage, design and distribute survey questionnaires, establish relevant evaluation criteria, construct a matrix to calculate weights, obtain the final evaluation results, and based on this, provide targeted suggestions for XM Airlines to improve service quality, further discuss and prospect. Research has found that the overall quality of XM Airlines baggage check-in is at a satisfactory level, but there is still room for improvement in terms of reliability, security, and tangibility. Specific issues include damaged or lost luggage, cumbersome compensation processes, and delayed updates to luggage status. In response to the above issues, it is recommended that XMAirlines enhance its existing intelligent technology, optimize service processes, strengthen resource and facility management to effectively improve luggage check-in efficiency and accuracy, enhance passenger satisfaction and trust, and thus enhance the airline's market competitiveness

    CANONICAL ABERRATION THEORY IN ELECTROMAGNETIC MULTIPOLES

    No full text
    In a 2N-pole electromagnetic system, defining the electron optical Hamiltonian function, we have derived both general algebraic expressions (arbitrary N) and special numerical formulas (N = 3,4,5,6,7) for different aberrations from lower to higher order (i.e., the order of N - 1, N + 1, 2N - 3, 2N - 1, 3N - 5). The so-called canonical aberration theory in electromagnetic multipoles has thus been developed, which allows us to deduce angular dependencies of different aberrations and to examine the possibility for spherical correction of a round lens by using multipoles.Physics, AppliedSCI(E)0ARTICLE125968-59756

    Further study on the mechanism of cleavage fracture at low temperatures

    No full text
    On the basis of finite element analyses of stress and strain ahead of a precrack tip and\ud metallographic observation, the RKR model for cleavage fracture was reviewed, and the following\ud conclusions were made: the critical event for cleavage fracture of a precracked specimen of C-Mn steel,\ud tested around - 100°C, is the propagation of a second phase particle-sized crack into the neighbouring\ud ferrite grain; there is a minimum distance Xm~ n from the precrack tip to the initiation position of cleavage\ud fracture. This Xm~n is not determined by the criterion of the principal stress Oyy exceeding the cleavage stress\ud trf, or the probability assuring the presence of an "eligible" cracked particle for which the criterion is\ud satisfied. The Xm~ n has a definite physical meaning at which triaxiality %/6 reaches the critical value Tc,\ud to prevent a produced crack nucleus from blunting. From the Xmi n and the measured cleavage stress af,\ud the lower boundary value of K~c in the lower shelf of the transition curve could be calculated. A physical\ud model for the statistical description of the scattering of the measured value of K~ c from its lower boundary\ud value is suggested

    Removal of ammonium from rare-earth wastewater using natural brucite as a magnesium source of struvite precipitation

    No full text
    This paper presents a study regarding ammonium removal from rare-earth wastewater by struvite precipitation with natural brucite mineral as a source of magnesium. Experimental results indicated that a pH ranging from 8.5 to 9.5 was the optimum for the removal of ammonium using the soluble form of brucite as a magnesium source. Additionally, when solid brucite was used as a magnesium source as well as an alkali reagent, the initial ammonium concentration of 4,535 mg/L decreased to 239–317 mg/L after an reaction time of 12 h in wastewater treated with the S/L (solid brucite/liquid wastewater) ratios ranging from 31.2 to 63.2 g/L. Furthermore, as some non-reacted brucite still remained in the precipitates obtained at the end of reaction, the precipitates were subjected to reuse. The reuse results demonstrated that the reuse of the precipitates obtained with 63.2 g/L was feasible, and almost half of the brucite dose could be saved.</jats:p

    Architectural design and evaluation of an efficient Web-crawling system

    No full text
    This paper presents an architectural design and evaluation result of an efficient Web-crawling system. The design involves a fully distributed architecture, a URL allocating algorithm, and a method to assure system scalability and dynamic reconfigurability. Simulation experiment shows that load balance, scalability and efficiency can be achieved in the system. Currently this distributed Web-crawling subsystem has been successfully integrated with WebGather, a well-known Chinese and English Web search engine, aimed at collecting all the Web pages in China and keeping pace with the rapid growth of Chinese Web information. In addition, we believe that the design can also be useful in other context such as digital library, etc. (C) 2002 Elsevier Science Inc. All rights reserved.Computer Science, Software EngineeringComputer Science, Theory &amp; MethodsSCI(E)EI6ARTICLE3185-1936
    corecore