1,720,953 research outputs found
Study of the effectiveness of fructose-1,6-diphosphate in the complex treatment of cardiac surgery patients who underwent coronary artery bypass grafting with cardiopulmonary bypass
Background. Coronary heart disease is the accumulation of atherosclerotic plaques in the blood vessels that supply the heart with oxygen and nutrients. Coronary artery bypass grafting is a strategy for myocardial revascularization that is indicated for patients with three or more coronary artery damage, high SYNTAX, diabetes, and left ventricular systolic dysfunction. In the vast majority of cases, CABG is currently performed with cardiopulmonary bypass. During the cardiopulmonary bypass, under the influence of a number of factors, there is a decrease in the level of some electrolytes. One of them is phosphorus — an important element for all living cells, which performs various functions. The purpose of the study was to study the effectiveness of fructose-1,6-diphosphate in order to prevent and reduce the severity of acute left ventricular failure in patients who underwent surgery — coronary artery bypass grafting with cardiopulmonary bypass, in which hypophosphatemia was detected before surgery. Materials and methods. 500 patients were operated on at the State Scientific Institution “Scientific and Practical Center of Preventive and Clinical Medicine” of the Agency of State Affairs. All underwent coronary artery bypass graft surgery with cardiopulmonary bypass. 60 patients were selected who were diagnosed with hypophosphatemia at the preoperative stage. Hypophosphatemia refers to a decrease in phosphate levels below normal, or levels approaching the lower limit of normal. The main group included 30 patients, for the correction of phosphate levels used fructose-1,6-diphosphate (drug Esafosfina). The control group also included 30 patients, no correction of phosphate levels was performed. No statistically significant differences in groups (by sex, age, number of bypasses imposed) were found, p > 0.05. The study of phosphate levels was performed before surgery, immediately after the end of cardiopulmonary bypass and in the early postoperative period in the dynamics. Results. The introduction of fructose-1,6-diphosphate was carried out (according to the manufacturer’s instructions) in an amount of 10 g as an intravenous infusion during cardiopulmonary bypass. An increase in the level of phosphates with fructose-1,6-diphosphate after administration of the drug in the main group, p < 0.05. Hemodynamic disorders after surgery, in the case of fructose-1,6-diphosphate, occurred 1.76 times less often (p < 0.05) than in the group where the correction of hypophosphatemia was not performed. In the case of acute left ventricular failure after CABG with artificial circulation, the recovery time of hemodynamics from surgery to stabilization was twice (p < 0.05) shorter in the main group compared with the control. And the amount of inotropic drug (dobutamine) consumed in the main group was 2.6 times (p < 0.05) less than in the control group. Conclusions. The use of the fructose-1,6-diphosphate in the complex treatment of cardiac surgery patients who underwent coronary artery bypass grafting with cardiopulmonary bypass, significantly corrects hypophosphatemia (increases phosphate levels). Administration of fructose-1,6-diphosphate reduces the incidence of acute left ventricular failure after CABG with cardiopulmonary bypass, in a group of patients who were diagnosed with hypophosphatemia before surgery. In case of its development, the appointment of fructose-1,6-diphosphate leads to a reduction in the recovery time of hemodynamics and a reduction in the total dose of inotropic drug (dobutamine), necessary to achieve stabilization
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
Author-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
In Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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