1,721,039 research outputs found
Lower oddball event-related EEG delta and theta responses in patients with dementia due to Parkinson's and Lewy body than Alzheimer's disease
No full textOddball task-related EEG delta and theta responses are associated with frontal executive functions, which are significantly impaired in patients with dementia due to Parkinson's disease (PDD) and Lewy bodies (DLB). The present study investigated the oddball task-related EEG delta and theta responses in patients with PDD, DLB, and Alzheimer's disease dementia (ADD). During visual and auditory oddball paradigms, EEG activity was recorded in 20 ADD, 17 DLB, 20 PDD, and 20 healthy (HC) older adults. Event-related EEG power spectrum and phase-locking analysis were performed at the delta (1–4 Hz) and theta (4–7 Hz) frequency bands for target and nontarget stimuli. Compared to the HC persons, dementia groups showed lower frontal and central delta and theta power and phase-locking associated with task performance and neuropsychological test scores. Notably, this effect was more significant in the PDD and DLB than in the ADD. In conclusion, oddball task-related frontal and central EEG delta and theta responses may reflect frontal supramodal executive dysfunctions in PDD and DLB patients
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Kırıkkale yöresindeki sığır işletmelerinden toplanan yem ve süt örneklerinde mikotoksin kalıntısının araştırılması
No full textProje -- Kırıkale Üniversitesi2011/41101639
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
The investigation of the effect of levamisole on oxidative stress and cytokines in rats exposed to lead poisoning
No full textLevamizol, veteriner hekimlikte antelmintik ve immunmodulatör olarak kullanılan bir ilaçtır. Kurşun, zehirliliği çok iyi bilinen çevre kirletici bir metaldir. Bu çalışmanın amacı, kurşun zehirlenmesi oluşturulan ratlarda immunomodulatör etkili levamizolun oksidatif stres ve sitokin cevap üzerine etkisinin araştırılmasıdır. Çalışma Kırıkkale Üniversitesi Hayvan Deneyleri Yerel Etik Kurulu (Etik no:16/82) tarafından onaylandı. Çalışmada 40 adet, 2-3 aylık erkek Wistar rat kullanıldı. Ratlar 10 ' ar lık 4 gruba ayrıldı. Kontrol grubu olan birinci gruba gavaj ile fizyolojik tuzlu su (FTS), ikinci gruba gavaj ile FTS ve içme suyuna 2000 ppm kurşun asetat, üçüncü gruba 2 mg/kg gavaj ile levamizol, dördüncü gruba ise 2 mg/kg gavaj ile levamizol ve 2000 ppm kurşun (Pb) asetat içme suyuna 5 hafta boyunca verildi. Çalışmanın sonunda, anestezi altında kanları kalpten alındı. Heparinli tüplerdeki kan örnekleri, 3000 rpm'de 10 dakika santrifüj edilip, plazmaları ayrıldı. Alanin amino transferaz (ALT), alkalin aminotransferaz (AST), alkalin fosfataz (ALP) aktiviteleri ve albumin, kreatinin, total protein, trigliserid, total kolesterol, ürik asit, total bilirubin, düşük yoğunluklu lipoprotein (LDL-kolesterol), yüksek yoğunluklu lipoprotein (HDL-kolesterol), kalsiyum, glikoz değerleri otoanalizör cihazında okundu. Aynı zamanda malondialdehid (MDA) aktivitesi ölçüldü ve ticari kitlerle superoksiddismutaz, katalaz, IL18, IFN-gama (IFN ? ) ve IgE, IgG seviyelerine mikroplak okuyucu ile bakıldı. Yapılan analiz sonucunda, 5 hafta boyunca 2000 ppm Pb asetat verilen grupta MDA aktivitesi, kontrol ve 2 mg/kg levamizol verilen gruba göre istatistiksel olarak anlamlı arttığı; buna karşılık Pb+L grubunda, Pb grubuna göre istatistiksel olarak azaldığı tespit edilmiştir (P?0,001). Süperoksid dismutaz (SOD) değerinin, Pb+ levamizol verilen gruplarda, Pb verilen gruba göre istatistiksel olarak anlamlı şekilde arttığı tespit edilmiştir (P=0,029). Katalaz (CAT) değerinin, Pb verilen grupta levamizol, kontrol ve Pb+levamizol grubuna göre önemli düzeyde arttığı tespit edilmiştir (P?0,001). IL 18 ile IFN ? aktivitelerinde deneme grupları arasında istetistiksel olarak önemli bir fark bulunamamıştır (P>0,05). Ig G değeri levamizol ve Pb+levamizol gruplarında Pb grubuna göre anlamlı derecede artmıştır (P?0,01). Ig E ise gruplar arasında istatistiksel olarak farklılık tespit edilmemiştir. (P>0,05). Plazma ALT aktivitesi ve total kolesterol düzeyi Pb verilen grupta diğer çalışma gruplarına göre istatistiksel olarak daha yüksek bulunmuştur; levamizol uygulaması yükselen ALT ve total kolesterol seviyesini anlamlı olarak düşürmüştür (P 0.05). Ig G levels were significantly higher in the levamisole and Pb + levamisole groups than in the Pb group (P?0.01). Ig E was not statistically different among the groups (P> 0.05). Plasma ALT activity and total cholesterol level were statistically higher in the Pb group than in the other experimental groups, and levamisole administration significantly lowered elevated ALT and total cholesterol levels (P <0.001). The results of the study suggest that levamisole may find additional use in the treatment of lead poisoning; also it has been concluded that further studies can be achieved by conducting further studies in organs such as the liver and brain, which are most affected by lead. Key words: Cytokines, lead, levamisole, rat, oxidative stres
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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