1,724,325 research outputs found
Xuebin Wang's Quick Files
No full textThe Quick Files feature was discontinued and it’s files were migrated into this Project on March 11, 2022. The file URL’s will still resolve properly, and the Quick Files logs are available in the Project’s Recent Activity
Xuebin Wang's Quick Files
No full textThe Quick Files feature was discontinued and it’s files were migrated into this Project on March 11, 2022. The file URL’s will still resolve properly, and the Quick Files logs are available in the Project’s Recent Activity
Bone tissue engineering : biomimetic structures for human osteoprogenitor growth
No full textIn vitro and in vivo approaches to investigate the ability to generate biomimetic scaffolds for bone tissue engineering included the use of 1) surface-modification of an biodegradable polymer scaffold with GRGDS peptide, fibronectin (FN), 2) Saos-2 'retentate' extracts (BMP's), 3) recombinant human pleiotrophin (rhPTN) and, 4) recombinant human bone morphogenetic protein-2 (rhBMP-2). In addition, the potential of growth factor encapsulation and gene therapy to deliver growth factors to modulate human osteoprogenitors adhesion and differentiation was examined. Human osteoprogenitors were shown to adhere, differentiation and to mineralised on FN and GRGDS coupled polymer films as well as on three-dimensional (3-D) biodegradable scaffolds indicating the potential to generate porous scaffolds with the ability to mimic the biological microenvironments for cell growth. Saos-2 cell 'retentate' extract, which contains a mixture of BMP's, stimulated human osteoprogenitor adhesion, growth and differentiation on poly(-lactic acid co÷glycolic acid) (PLGA) (75:25) porous scaffolds. 3-D biomimetic structures adsorbed with rhPTN maintained the ability to modulate human osteoprogenitor activity resulting in new cartilage and bone matrix formation both in vitro and in vivo. Human BMP-2 gene adenoviral transfer into human bone marrow stromal cells confirmed the possibility of using gene therapy to engineer bone tissue. Furthermore, rhBMP-2 encapsulated within PLA porous scaffolds by a supercritical fluid mixing method, stimulated C2C12 cell differentiation and promoted human osteoprogenitor proliferation, differentiation as well as new cartilage and bone formation on 3-D PLA scaffolds in vivo. In conclusion, these studies indicates that the ability to generate osteoinductive and osteoconductive biomimetic scaffold using biodegradable polymers in combination with osteogenic growth factors to create a biomimetic microenvironment for human osteoprogenitor growth and to generate templates for the development of a living tissue substitute for bone.</p
Xuebin Wang's Quick Files
No full textThe Quick Files feature was discontinued and it’s files were migrated into this Project on March 11, 2022. The file URL’s will still resolve properly, and the Quick Files logs are available in the Project’s Recent Activity
A Study on the Cost Competitiveness of International Short Sea Shipping in Korea-Japan Route : Lo-Lo and Ro-Ro Shipping Transport
Get PDFWith the rapid growth of international trade, international logistics has become a significant economic activity today. Under these circumstances, companies are continually striving to improve logistics processes, reduce logistics costs, and maximize the efficiency of the supply chain to achieve better performance. In the development of international logistics, maritime transport has always been the most critical mode of transportation and a vital component of the supply chain. To enhance maritime transportation efficiency and realize more smooth international multimodal transportation, container transportation system appeared in the 1950s and Ro-Ro transportation through container was gradually getting popular. Recently, European and North American advanced countries are actively fostering international short sea shipping to reduce environmental pollution and congestion caused by road transportation and to improve the efficiency of the transportation network in the region. The Ro-Ro ship is attracting attention as a significant transportation means for short sea shipping due to its advantages of quick and convenient loading and unloading system.
Northeast Asia is geographically suitable for fostering short sea shipping and economic cooperation among countries in the region is actively underway. However, the market share of Ro-Ro transportation is abysmal compared to traditional Lo-Lo transportation. States in this area are also attempting various cooperation to improve international logistics efficiency. Among them, Korea and Japan are supporting the development of a seamless logistics process by encouraging the companies of both countries with the government-led initiative. A representative example is the double number trailer pilot project based on Ro-Ro transportation which started from 2013. Therefore, it is necessary to have an accurate understanding of the competitiveness of Ro-Ro and Lo-Lo in Northeast Asia's short sea shipping market. For this purpose, this study builds a model to estimate the total logistics cost of two transportation means. And analyze the cost competitiveness of Lo-Lo and Ro-Ro in general situations. Also, the model is applied to estimate the total logistics cost of the double number trailer demonstration project and suggest the growth potential of Ro-Ro transportation method.
The total logistics costs of Lo-Lo and Ro-Ro were calculated by selecting Busan-Hakata, Busan-Shimonoseki and Busan-Osaka routes and applying the same conditions. As a result, the cost competitiveness of Lo-Lo is higher than Ro-Ro on most routes, and Ro-Ro is competitive only for high-value cargo transportation. However, as a result of the total logistics costs of the double number pilot project, Ro-Ro reduced total logistics costs by about $435 per FEU compared to Lo-Lo by reducing freight packaging costs. Also, Ro-Ro transport achieved seamless supply chain, which significantly decreased lead time. Future research needs to extend the scope of the study to include other countries in Northeast Asia such as China. Also, it is necessary to increase the accuracy of the analysis results by applying more variables to affect total logistics cost. Finally, it is essential to change the perception of competitiveness in Ro-Ro transportation. Ro-Ro systems should be regarded as the core of a more sustainable short sea shipping supply chain that integrates maritime transport and port-handling operations, and more in-depth research is needed.제 1 장 서 론 1
1.1 연구 배경 및 목적 1
1.2 연구 방법 및 구성 5
제 2 장 선행연구 고찰 8
2.1 국제근해운송 관련 선행연구(Lo-Lo, Ro-Ro) 8
2.2 운송수단 선택 관련 선행연구 14
2.3 화물 시간가치 산정 관련 선행연구 16
2.4 시사점 17
제 3 장 한국-일본 노선 Lo-Lo/Ro-Ro 운영현황 분석 19
3.1 Lo-Lo 및 Ro-Ro 운송 개요 19
3.2 한국-일본 노선 컨테이너 물동량 현황 20
3.3 한국-일본 주요 정기선 노선 현황 25
3.4 소결 32
제 4 장 한국-일본 노선 Lo-Lo/Ro-Ro 총 물류비용 분석 33
4.1 분석개요 33
4.2 총 운임 분석 34
4.3 시간비용 분석 37
4.4 포장비용 분석 44
4.5 한국-일본 노선 Lo-Lo/Ro-Ro 총 물류비용 분석 46
4.6 소결 63
제 5 장 한일 더블넘버 트레일러 시범사업 총 물류비용 산정 65
5.1 시범사업 소개 65
5.2 시범사업 총 물류비용 산정 75
제 6 장 결 론 79
6.1 연구결과 요약 79
6.2 연구의 한계 및 향후 연구방향 83
참고문헌 85
부 록 91Docto
Inter-receiver traveltimes of Love wave around the British Isles
No full textThis dataset contains inter-receiver Love wave traveltimes among 61 seismometers around the British Isles. The data was originally obtained by cross-correlation of ambient noise data recorded by the 61 receivers during 2001 to 2003, 2006 to 2007 and in 2010. More details can be found in Transdimensional Love-wave tomography of the British Isles and shear-velocity structure of the East Irish Sea Basin from ambient-noise interferometry (https://doi.org/10.1093/gji/ggw286) and Interrogating Subsurface Structures using Probabilistic Tomography: an example assessing the volume of Irish Sea basins (https://doi.org/10.1002/essoar.10510266.1)
Bayesian Inversion, Uncertainty Analysis and Interrogation using Boosting Variational Inference
No full textThis dataset contains inter-receiver Love wave traveltimes among 61 seismometers around the British Isles. The data was originally obtained by cross-correlation of ambient noise data recorded by the 61 receivers during 2001 to 2003, 2006 to 2007 and in 2010. More details can be found in Transdimensional Love-wave tomography of the British Isles and shear-velocity structure of the East Irish Sea Basin from ambient-noise interferometry (https://doi.org/10.1093/gji/ggw286) and Interrogating Subsurface Structures using Probabilistic Tomography: an example assessing the volume of Irish Sea basins (https://doi.org/10.1029/2022JB024098). The dataset relates to the manuscript "Bayesian Inversion, Uncertainty Analysis, and Interrogation using Boosting Variational Inference"
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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