179 research outputs found
Immunogenicity of SAdV vectors boosted by MVA.
<p>Balb/c mice were immunised with 10<sup>6</sup> infectious units of AdC68-TIPeGFP, AdvY25TIPeGFP, or ChAd63 TIPeGFP. After 56 days post prime, mice were boosted with 10<sup>6</sup> pfu MVA-TIPeGFP. Blood was collected <b>A</b>, 55 post prime and <b>B</b>, 7 days post boost. Blood IFNγ<sup>+</sup> CD8<sup>+</sup> T cell responses were measured by intracellular cytokine staining (ICS) after stimulation with Pb9 peptide. No statistical significance was found between any of the groups by one way ANOVA.</p
Improving the maximum transmission distance of continuous-variable quantum key distribution with noisy coherent states using a noiseless amplifier
By employing a nondeterministic noiseless linear amplifier, we propose to increase the maximum transmission distance of continuous-variable quantum key distribution with noisy coherent states. With the covariance matrix transformation, the expression of secret key rate under reverse reconciliation is derived against collective entangling cloner attacks. We show that the noiseless linear amplifier can compensate the detrimental effect of the preparation noise with an enhancement of the maximum transmission distance and the noise resistance. (C) 2014 Elsevier B.V. All rights reserved.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000342256500002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Physics, MultidisciplinarySCI(E)[email protected]
Simultaneous fleet assignment and cargo routing using benders decomposition
In this paper, we incorporate the cargo routing problem into fleet assignment to model the fleet assignment more accurately. An integrated model and a Benders decomposition-based approach are developed to simultaneously obtain the optimal assignment of fleet to legs and the routing of forecasted cargo demand over the network. Computational experiments show that this integrated approach converges very fast for all different test scenarios
Ana Acevedo y sus hijas junto a la imagen de la Virgen del Rocío, en el Rocío Chico de 1953 (Fotografía). Fondo Hermandad Matriz de Nuestra Señora del Rocío de Almonte
Casa Hermandad Matri
ESM Figures from Substantially adaptive potential in polyploid cyprinid fishes: evidence from biogeographic, phylogenetic and genomic studies
Whole genome duplication (WGD) is commonly believed to play key roles in vertebrate evolution. However, nowadays polyploidy exists in a few fish, amphibian and reptile groups only, and seems to be an evolutionary dead-end in vertebrates. We investigate the evolutionary significance of polyploidization in Cyprinidae—a fish family that contains more polyploid species than any other vertebrate groups with integrating biogeographic, phylogenetic and genomic analyses. First, polyploid species are found to be significantly frequent in higher altitude and lower mean annual temperature areas compared to diploid species in Cyprinidae. Second, a polyploidy-related diversification rate shift is observed in Cyprinidae. It is that increased net diversification rate is only seen in three polyploid lineages, and other polyploid lineages have similar net diversification rate as well as diploid lineages in Cyprinidae. Interestingly, significant ‘lag-times’ existed between polyploidization and radiation in Cyprinidae. Multiple polyploid lineages were established approximately 15 Ma through recurrent allopolyploidization events but the net diversification rate did not start to increase until approximately 5 Ma—long after polyploidization events. Environmental changes associated with the continuous uplift of Tibetan Plateau and climate change have likely promoted the initial establishment and subsequent radiation of polyploidy in Cyprinidae. Finally, the unique retention of duplicated genes in polyploid cyprinids adapted to harsh environments is found. Taken together, our results suggest that polyploidy in Cyprinidae is far more than an evolutionary dead-end, but rather shows substantially adaptive potential. Polyploid cyprinids thus constitute an ideal model system for unveiling largely unexplored consequences of WGD in vertebrates, from genomic evolution to species diversification
Intersubband Transitions in Lead Halide Perovskite-Based Quantum Wells for Mid-Infrared Detectors
Due to their excellent optical and electrical properties
as well
as versatile growth and fabrication processes, lead halide perovskites
have been widely considered as promising candidates for green energy
and applications related to optoelectronics. Here, we investigate
their potential applications at infrared wavelengths by modeling the
intersubband transitions in perovskite-based quantum well systems.
Both single-well and double-well structures are studied, and their
energy levels as well as the corresponding wave functions and intersubband
transition energies are calculated by solving the one-dimensional
Schrödinger equations. Via adjustment of the quantum well and
barrier thicknesses, the intersubband transition energies can be tuned
to cover a broad infrared wavelength range. We also find that the
lead halide perovskite-based quantum wells possess high absorption
coefficients. The widely tunable transition energies and high absorption
coefficients of the perovskite-based quantum well systems, combined
with their unique material and electrical properties, may enable an
alternative material system for infrared photodetector applications
Microgravimetric Analysis Method for Activation-Energy Extraction from Trace-Amount Molecule Adsorption
Activation-energy
(Ea) value for trace-amount
adsorption of gas molecules on material is rapidly and inexpensively
obtained, for the first time, from a microgravimetric analysis experiment.
With the material loaded, a resonant microcantilever is used to record
in real time the adsorption process at two temperatures. The kinetic
parameter Ea is thereby extracted by solving
the Arrhenius equation. As an example, two CO2 capture
nanomaterials are examined by the Ea extracting
method for evaluation/optimization and, thereby, demonstrating the
applicability of the microgravimetric analysis method. The achievement
helps to solve the absence in rapid quantitative characterization
of sorption kinetics and opens a new route to investigate molecule
adsorption processes and materials
Quantum Photon Sources in WSe<sub>2</sub> Monolayers Induced by Weakly Localized Strain Fields
Quantum emitters in semiconductor transition metal dichalcogenide
(TMD) monolayers hold great promise for many quantum optics applications
due to the intriguing properties afforded by the host materials. The
creation of localized excitonic states in two-dimensional semiconductors
is also fundamentally interesting. Local strain engineering of TMD
monolayers has been attested to be a viable approach for creating
quantum emitters. However, despite the ubiquitous existence of local
topography variations in the structures used to create strain gradients
in the TMD monolayers, an understanding of their influence on the
strain fields and exciton trapping is notably lacking, especially
on the nanoscale. In this study, we investigate WSe2 monolayers
deposited on the edges of as-fabricated trenches, which are deemed
to induce 1D delocalized strain profiles in the monolayers, and observe
optical signatures of weakly confined excitonic states supporting
biexciton emission. Our numerical simulations of the strain distributions
suggest that the quantum emitters originate from quasi-1D like localized
strain profiles induced by local topography variations at the trench
edges. These findings have strong implications toward the controlled
creation of quantum emitters in TMD monolayers and their efficient
coupling to photonic structures
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