3,098 research outputs found
Deng Deng
No full textabstract: Deng Deng was six years old when the Arabs attacked his village.
“Lost Boys Found” is an ongoing, interdisciplinary project that is collecting, recording and archiving the oral histories of the Lost Boys/Girls of Sudan. The collection is a work-in-progress, seeking to record the oral history of as many Lost Boys/Girls as are willing, and will be used in a future book.Age: 20Region: WeilThis picture and bio was donated to the Lost Boys Found project from The Arizona Lost Boys Cente
Deng Atem
No full textabstract: Deng Atem witnessed his village being burned and people being killed. He was seven years old when the militia came into his village.
“Lost Boys Found” is an ongoing, interdisciplinary project that is collecting, recording and archiving the oral histories of the Lost Boys/Girls of Sudan. The collection is a work-in-progress, seeking to record the oral history of as many Lost Boys/Girls as are willing, and will be used in a future book.Age: 27Region: Bahr al GhazalThis picture and bio was donated to the Lost Boys Found project from The Arizona Lost Boys Cente
Malek Deng
No full textabstract: Malek Deng left his home at the age of seven because his village was attacked.
“Lost Boys Found” is an ongoing, interdisciplinary project that is collecting, recording and archiving the oral histories of the Lost Boys/Girls of Sudan. The collection is a work-in-progress, seeking to record the oral history of as many Lost Boys/Girls as are willing, and will be used in a future book.Age: 28Region: Bahr al GhazalThis picture and bio was donated to the "Lost Boys Found" oral history project from The Arizona Lost Boys Cente
Role of the MPN subunits in COP9 signalosome assembly and activity, and their regulatory interaction with Cullin3-based E3 ligases
No full textThe COP9 signalosome (CSN) is an evolutionarily conserved multisubunit protein complex that regulates a variety of biological processes. Among its eight subunits, CSN5 and CSN6 contain a characteristic MPN (for Mpr1p and Pad1p N-terminal) domain and, in Arabidopsis thaliana, are each encoded by two genes: CSN5A, CSN5B and CSN6A, CSN6B, respectively. We characterized both MPN subunits using a series of single and double mutants within each gene family. Our results indicate that although CSN6A and CSN6B retain mostly redundant functions, CSN5A and CSN5B play unequal roles in the regulation of plant development. Complete depletion of either of the two MPN members results in CSN instability and the decay of various CSN components, along with the complete loss of CUL1, CUL3, and CUL4 derubylation. Furthermore, we demonstrate that CSN interacts with CUL3, in addition to CUL1 and CUL4, and that the lack of CSN activity differentially affects the stability of those three cullins. Interestingly, we also show that optimal CUL3 activity is required to maintain the cellular pool of CSN5, through a posttranscriptional mechanism. Our data suggest the existence of reciprocal regulation between CUL3 and CSN5 accumulation. This study thus completes the genetic analysis of all CSN subunits and confirms the structural interdependence between PCI and MPN subunits in functional CSN complex formation
Peter Deng
No full textabstract: Peter was five years old when he left the village with his sister.
“Lost Boys Found” is an ongoing, interdisciplinary project that is collecting, recording and archiving the oral histories of the Lost Boys/Girls of Sudan. The collection is a work-in-progress, seeking to record the oral history of as many Lost Boys/Girls as are willing, and will be used in a future book.Age: 20Region: Upper NileThis picture and bio was donated to the "Lost Boys Found" oral history project from The Arizona Lost Boys Cente
Abraham Deng Magot
No full textabstract: Abraham left his village when war broke out and without food it was difficult to survive. Along with other boys, he ate grass and learned to clean muddy water for drinking.
“Lost Boys Found” is an ongoing, interdisciplinary project that is collecting, recording and archiving the oral histories of the Lost Boys/Girls of Sudan. The collection is a work-in-progress, seeking to record the oral history of as many Lost Boys/Girls as are willing, and will be used in a future book.Age: 26Region: Upper NileThis picture and bio was donated to the "Lost Boys Found" oral history project from The Arizona Lost Boys Cente
FIN219, an auxin-regulated gene, defines a genetic link between phytochrome A and the downstream regulator COP1 in light control of Arabidopsis development
No full textDELLA-mediated PIF degradation contributes to coordination of light and gibberellin signalling in Arabidopsis
No full textLight and gibberellins (GAs) antagonistically regulate hypocotyl elongation in plants. It has been demonstrated that DELLAs, which are negative regulators of GA signalling, inhibit phytochrome-interacting factors 3 and 4 (PIF3 and PIF4) by sequestering their DNA-recognition domains. However, it is unclear whether there are other mechanisms of regulatory crosstalk between DELLAs and PIFs. Here, we demonstrate that DELLAs negatively regulate the abundance of four PIF proteins through the ubiquitin-proteasome system. Reduction of PIF3 protein abundance by DELLAs correlates closely with reduced hypocotyl elongation. Both sequestration and degradation of PIF3 by DELLAs contribute to a reduction in PIF3 binding to its target genes. Thus, we show that promotion of PIF degradation by DELLAs is required to coordinate light and GA signals, and the dual regulation of transcription factors by DELLAs by both sequestration and degradation may be a general mechanism.National Natural Science Foundation of China [31330048, 31271294]; National Program on Key Basic Research Project of China [2012CB910900]; NIH of United States [GM-47850]; Peking-Tsinghua Center for Life Sciences; State Key Laboratory of Protein and Plant Gene ResearchSCI(E)[email protected]; [email protected]
Deng Erya jiu cang jia gu.
No full text李宗焜拓摹并題."鄧爾雅(一八八四-一九五四)舊藏甲骨. 一九六九年五月鄧祖玄奉母葉多福女士之命以其父爾雅先生所藏甲骨慨贈香港中文大學聯合書院. 二〇一五年夏移藏大學圖書館""乙未仲冬余應香港中文大學圖書館李露絲館長之邀為館藏甲骨之儲存與展示貢愚余以坐言不如起行遂為之董理重為類次並施拓摹携歸裱冊而還之且識數語以記因緣李宗焜於史語所""Deng Erya (yi ba ba si - yi jiu wu si) jiu cang jia gu. Yi jiu liu jiu nian wu yue Deng Zuxuan feng mu Ye Duofu nü shi zhi ming yi qi fu Erya xian sheng suo cang jia gu kai zeng Xianggang Zhong wen da xue Lian he shu yuan. Er ling yi wu nian xia yi cang Da xue tu shu guan""Yi wei zhong dong yu ying Xianggang Zhong wen da xue tu shu guan Li Lusi guan zhang zhi yue wei guan cang jia gu zhi chu cun yu zhan shi gong yu yu yi zuo yan bu ru qi xing sui wei zhi dong li chong wei lei ci bing shi tuo mo xie gui biao ce er huan zhi qie shi shu yu yi ji yin yuan Li Zongkun yu Shi yu suo"In accordion binding.Li Zongkun tuo mo bing ti
Regulation by the COP9 signalosome of AtPIC2, an F-box protein from Arabidopsis thaliana
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