196,747 research outputs found
Wuttke, M, 424041
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/427451Surname: WUTTKE. Given Name(s) or Initials: M. Military Service Number or Last Known Location: 424041. Missing, Wounded and Prisoner of War Enquiry Card Index Number: SEA-4581.250585
Item: [2016.0049.59712] "Wuttke, M, 424041
Selbstorganisation als didaktisches Prinzip in der akademischen Lehre? Subversive Betrachtung aus Sicht verschiedener Disziplinen und Gruppen von Betroffenen
No full textWuttke E, Zimmermann M, Goldhorn M, Wild E. Selbstorganisation als didaktisches Prinzip in der akademischen Lehre? Subversive Betrachtung aus Sicht verschiedener Disziplinen und Gruppen von Betroffenen. In: Rausch A, Warwas J, Seifried J, Wuttke E, eds. Konzepte und Ergebnisse ausgewählter Forschungsfelder der beruflichen Bildung - Festschrift für Detlef Sembill. Baltmannsweiler: Schneider Verlag Hohengehren; 2015: 383-402
Metabolic effects of 20-OH-Ecdysone in ovariectomized rats
No full textPostmenopausal women develop often obesity which may be prevented by 20-OH-Ecdysone (Ecd) This was investigated in ovanectomized (ovx) rats They were orally treated with 3 doses of Ecd (18, 56 or 116 mg/day/animal) Positive controls received 159 mu g estradiol (E2). Quantitative computer tomography at the level of the abdomen and the metaphysis of the tibia allowed estimation of surface, fat depots and muscles The highest dose of Ecd resulted in serum concentrations of 0.4 X 10(-6) M Serum E2 concentrations in the positive controls were 73 3 +/- 24 41 pg/ml E2 but not Ecd stimulated uterine weights Under Ecd ovx animals gained less fat but had more muscle mass Serum TSH, T4 and T3 levels remained unaffected while E2 treatment increases T4 but decreases T3 levels Ecd at the lowest dose lowered serum LDL and did not result in increased serum triglycerides, an effect seen in the E2 treated rats At the Ecd highest dose serum HDL was higher than in the controls In conclusion Ecd has beneficial effects on fat and muscle tissue and may be able to prevent the metabolic syndrome and sarcopenia by a non-estrogenic mechanism (C) 2010 Elsevier Ltd All rights reserve
Pharmacokinetics of human chorionic gonadotropin after i.m. administration in goats (Capra hircus)
No full textThe present investigation addresses the pharmacokinetics of human chorionic gonadotropin (hCG), intramuscularly (i.m.) administered to goats. Nine pluriparous does of the Boer goat breed, 2-6 years of age and weighing 45-60 kg, were administered 500 IU hCG (2 ml Chorulon) deep into the thigh musculature 18 h after superovulatory FSH treatment. Blood samples were drawn from the jugular vein at 2 h intervals for the first 24 h, at 6 h intervals until 42 h, and at 12 h intervals until 114 h after administration. After centrifugation, plasma hCG concentrations were determined by electrochemiluminescence immunoassay. Pharmacokinetical parameters were as follows: lag time, 0.4 (S. E. M. 0.1) h; absorption rate constant, 0.34 (S. E. M. 0.002) h; absorption half-life, 2.7 (S. E. M. 0.5) h; elimination rate constant, 0.02 (S. E. M. 0.002) h; biological half-life, 39.4 (S. E. M. 5.1) h; and apparent volume of distribution, 16.9 (S. E. M. 4.3) I. The plasma hCG profile was characterized by an absorption phase of 11.6 (S. E. M. 1.8) h and an elimination phase of 70.0 (S. E. M. 9.8) h, with considerable individual variation in bioavailability and pharmacokinetical parameters. Biological half-life was negatively correlated (P<0.05) with peak concentration (r=-0.76), absorption rate constant (r=-0.78), and elimination rate constant (r=-0.87). The results indicate that after rapid absorption, hCG remains in the circulation for an extended period. This has to be taken into account when assessing the stimulatory response to hCG treatment on an ovarian level. Reproduction (2012) 144 77-8
Numerical analysis of thermal cycling during a multi-stage energy pile thermal response test
No full textEnergy piles are emerging as convenient alternative to the more traditional borehole heat exchangers (BHEs) to provide heating/cooling to buildings, as they remove the need for special purpose excavations and can accommodate more pipes, thus enhancing energy performance. However, their different aspect ratio compared to BHEs requires different modelling tools and dedicated thermal response testing, to achieve adequate thermal design. In this work, the results of an extended multi-stage thermal response test (TRT) carried out on a single energy pile installed in London Clay are presented in terms of both fluid temperature data and concrete temperature, measured by vibrating wire strain gauges and optic fibre sensors. The results are then explored in detail by means of a finite element numerical code, able to account for both convective heat exchange in the fluid, between the fluid and the solids and transient heat diffusion in the concrete and the ground. Analysis of the TRT field data shows that during the later stages of the test there is clear evidence of cyclic changes in performance. Investigation of these effects using the numerical model raises the possibility that there could be some alteration of the properties of the soil-pile contact during the test. Hypotheses for the observed behaviour are tentatively put forward and discussed with work recommended to further investigate the percieved phenomena
Adrenal release of catecholamines and Met-enkephalin before and after stress as measured by a novel in vivo dialysis method in the rat
No full textEffects of acute i.v. infusion and 5-day styrene inhalation on neuroendocrine function in male rats.
No full textEffects of acute i.v. infusion and 5-day styrene inhalation on neuroendocrine function in male rats.
No full textEvaluation of the antiosteoporotic potential of Tinospora cordifolia in female rats
No full textThe available courses of therapy to osteoporosis in menopausal women are limited by several side effects generated. A need therefore arises to explore herbal alternatives that are effective and safe. Objective: Present animal studies were conducted to investigate the potential of Tinospora cordifolia (TC) ethanolic stem extract as an antiosteoporotic agent. Methods: Three-month-old female Sprague-Dawley rats were either ovariectomized (ovx) or sham operated and treated with vehicle (benzyl benzoate:castor oil; 1:4), E-2 (1 mu g/day) or TC (10, 50, 100 mg/kg b.wt) subcutaneously for 4 weeks. At the end of experiment bone mineral density of tibiae was measured by quantitative computer tomography. Serum was analyzed for the activity of alkaline phosphatase and levels of osteocalcin, cross-laps and lipids. Uterus and mammary gland were processed for histological studies. Results: Ovx rats treated with TC (10 mg/kg b.wt) showed an osteoprotective effect as the bone loss in tibiae was slower than ovx controls. Serum osteocalcm and cross-laps levels were significantly reduced. All the above effects of TC were much milder than those produced by E-2. Alkaline phosphatase activity was higher in TC treatment groups. Total cholesterol and LDL levels remained unaltered but HDL levels were significantly lowered with TC (50 mg/kg b.wt) treatment. Uterus and mammary gland showed no signs of proliferation after treatment with TC extract. Conclusion: TC extract showed estrogen like effects in bone but not in reproductive organs like uterus and mammary gland. Thus, this Study demonstrates that extract of T cordifolia has the potential for being used as antiosteoporotic agent. (C) 2008 Elsevier Ireland Ltd. All rights reserved
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