1,721,019 research outputs found
Chirurgische und Interventionelle Behandlungsmöglichkeiten beim Adenokarzinom des Pankreas
Full text linkZusammenfassung. Bei nur einer Minderheit von 20 % der Patienten mit Pankreaskarzinom wird die Erkrankung in einem noch lokal begrenzten Stadium diagnostiziert, das eine primäre onkologisch radikale Resektion erlaubt, womit ein 5-Jahres Überleben von 20 bis 25 % erreicht wird. Aber auch bei sogenannt «borderline resectable» und «locally advanced» Befunden kann eine chirurgische Behandlung eventuell kombiniert mit intraoperativer irreversibler Electroporation in ausgewählten Situationen und im Rahmen von kombinierten Behandlungskonzepten eingesetzt werden, was die Prognose deutlich verbessert. In high-volume Zentren mit entsprechender Erfahrung können auch bei Tumoren mit begrenzter Infiltration der V.portae/V.mesenterica superior durch Venenresektion und -rekonstruktion radikale Resektionen erreicht werden.
Surgical and interventional treatment in pancreatic adenocarcinoma
Abstract. Only in a minority of 20 % of patients with pancreatic cancer the disease is diagnosed at a locally limited stage, that allows a R0 resection. This is associated with a 5year survival of 20 to 25 %. But also in so called «borderline resectable» and «locally advanced» disease surgical treatment combined with intraoperative irreversible electroporation can be applied in selected cases and in the context of multimodal treatment, thereby improving prognosis. In high-volume centers resections of tumors with limited venous involvement can be performed increase of R0 resections without significantly increasing morbidity and mortality
Elektive Splenektomie bei Erwachsenen – Vorbereitung, Durchführung und Nachbetreuung
No full textElective splenectomy in adults is often performed after failure of conservative treatment in patients with hematologic, neoplastic, or autoimmune disorders. The indication to perform a splenectomy should be discussed in an interdisciplinary team and the surgeon should not make the decision on his own. Laparoscopic splenectomy is nowadays established as the gold-standard treatment due to low morbidity and mortality and - compared to open surgery - lower postoperative pain, less intraoperative blood loss and shorter hospital stay. Every patient with planned splenectomy must undergo vaccination against pneumococci and meningococci at least two weeks prior to the operation, which helps reducing the risk of the "overwhelming post-splenectomy infection" (OPSI). Beside re-vaccination against pneumococci and meningococci during follow-up, every patient should be informed about the increased risk of infection, receive a personal post-splenectomy pass and emergency antibiotics in case of infectionDie elektive Splenektomie bei Erwachsenen wird häufig nach erfolgloser, konservativer Therapie bei hämatologischen, neoplastischen und autoimmunen Krankheiten durchgeführt. Die Indikation zur Splenektomie sollte bei allen Pa tienten interdisziplinär – und nicht durch den Chirurgen allein – gestellt werden. Die laparoskopische Splenektomie hat sich heutzutage als Gold-Standard eta bliert mit sehr geringer postoperativer Morbidität und Mortalität und im Vergleich zur offenen Methode weniger postoperativen Schmerzen und einem kür zeren Spitalaufenthalt. Spätestens zwei Wochen präoperativ müssen die Patienten erstmals gegen Pneumokokken sowie Meningokokken geimpft werden, um das Risiko einer „overwhelming post-splenectomy infection“ (OPSI) zu minimieren. Zusätzlich zur Auffrischimpfung im follow-up sollte jeder Patient über das erhöhte Infektrisiko informiert sein sowie einen Post-Splenektomie-Ausweis und ein Notfall-Antibiotikum auf sich tragen
Monolithic zirconia reconstructions supported by teeth and implants: 1- to 3-year results of a case series.
No full textOBJECTIVE
Today, only scarce information is available on monolithic zirconia reconstructions. The objective of this study was to evaluate the performance of monolithic zirconia for tooth- and implant-borne reconstructions.
METHOD AND MATERIALS
Monolithic zirconia single crowns (SCs) and fixed dental prostheses (FDPs) supported by implants or teeth were included in this study. Implant placement and prosthetic treatment were done in the same clinical setting. One technician performed all laboratory work using the same CAD/CAM workflow (DentalDesigner, Ceramill Motion 2, Amann Girrbach). The endpoints were technical outcome, color match, marginal adaptation, anatomical form, and biologic aspects. The modified United States Public Health Service (USPHS) criteria and periodontal parameters were applied for the clinical evaluation by two independent examiners. Descriptive statistics and nonparametric tests were used for statistical comparisons.
RESULTS
Forty patients (17 men, 23 women, mean age 59.1 ± 14.7 years) with 109 reconstructions (74 SCs, 35 FDPs) supported by 38 implants and 71 teeth were assessed, resulting in a total of 238 monolithic zirconia units (including 62 pontics and 18 cantilevers). Median follow-up time was 23.8 months (12 to 36 months). No technical failures were observed. The total prosthesis survival rate was 99.6% (teeth, 100%; implants, 98.4%) due to the loss of one implant. The periodontal/peri-implant parameters stand for healthy tissue, and caries was not detected. The records obtained by the USPHS revealed good clinical outcomes.
CONCLUSION
These short-term results indicate that monolithic zirconia reconstructions for teeth and implants may be a satisfactory treatment option, particularly in the posterior region
Endoscopic intra-abdominal rescue therapy of a dislodged EUS-guided hepaticogastrostomy stent.
Full text linkGoing Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
EUS-guided pancreaticogastrostomy and transgastric per-oral pancreatoscopy with electrohydraulic lithotripsy in a patient with chronic hereditary pancreatitis and several intraductal stones.
No full textEndoscopic rescue therapy of a distally perforated, retroperitoneal stent after EUS-guided pancreaticogastrostomy
Full text linkVariations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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