1,721,033 research outputs found
Histopathological follow-up after bailout stenting for early postoperative stenosis of a central aorto-pulmonary shunt
No full textWe treated a neonate with pulmonary atresia and a ventricular septal defect complicated by straddling of the atrioventricular valves by constructing a central aorto-pulmonary shunt. The postoperative course was complicated by obstruction of the shunt, which was treated by implantation of a coronary stent. Six months after the stenting, a Glenn anastomosis was created and the stented shunt removed. Analysis showed that the shunt was completely covered by a vascularized neointima. The stent had not produced injury to the shunt, with struts of the stent covered nicely by neoendothelium, with sparse inflammation surrounding the artificial implants
Histopathological follow-up after bailout stenting for early postoperative stenosis of a central aorto-pulmonary shunt
No full textWe treated a neonate with pulmonary atresia and a ventricular septal defect complicated by straddling of the atrioventricular valves by constructing a central aorto-pulmonary shunt. The postoperative course was complicated by obstruction of the shunt, which was treated by implantation of a coronary stent. Six months after the stenting, a Glenn anastomosis was created and the stented shunt removed. Analysis showed that the shunt was completely covered by a vascularized neointima. The stent had not produced injury to the shunt, with struts of the stent covered nicely by neoendothelium, with sparse inflammation surrounding the artificial implants
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Concurrent infection with Mycobacterium avium subsp. hominissuis and Giardia duodenalis in a chinchilla (Chinchilla lanigera f. dom.)
No full textA 3-year-old, female chinchilla (Chinchilla lanigera f. dom.) suffered from prolonged vaginal discharge. Sonographically, multiple nodules were detected in the uterus, and the lung showed a diffuse radiodensity, Ovario-hysterectomy was performed and histology of the uterus revealed a severe multifocal pyo-granulomatous metritis with myriads of acid-fast rod-shaped bacilli. Microbiological culture of formalin-fixed uterine tissue and a native vaginal swab resulted in the growth of mycobacteria that were identified as Mycobacterium (M.) avium subsp. hominissuis. The animal was euthanized and pathomorphological examination revealed severe multifocal granulomatous inflammation of lung, mediastinal and mesenteric lymph nodes, intestine, pancreas and kidneys. In addition, an infection of the small intestine with Giardia duodenalis was confirmed immunohistochemically. This is the first report describing a concurrent infection with M. avium subsp. hominissuis and Giardia duodenalis in a chinchilla. Both pathogens represent a potential health risk especially for young or immunosuppressed persons, in particular if infected animals show unspecific clinical symptoms.Ein dreijähriges, weibliches Chinchilla (Chinchilla lanigera f. dom.) zeigte anhaltenden Vaginalausfluss. Sonografisch wurden multiple, noduläre Umfangsvermehrungen im Uterus und eine diffuse Röntgendichte in der Lunge festgestellt. Es wurde eine Ovariohysterektomie durchgeführt und die histologische Untersuchung ergab eine hochgradige, multifokale pyo-granulomatöse Metritis mit unzähligen säurefesten stäbchenförmigen Bakterien. Die mikrobiologische Kultur von formalinfixiertem Uterusgewebe und einem nativen Vaginaltupfer führte zu einem Wachstum von Mykobakterien, die als Mycobacterium (M.) avium subsp. hominissuis identifiziert wurden. Das Tier wurde euthanasiert und pathomorphologisch wurden hochgradige, multifokale, granulomatöse Entzündungen in Lunge, mediastinalen und mesenterialen Lymphknoten, Darm, Pankreas und Nieren festgestellt. Zusätzlich wurde im Dünndarm immunhistologisch eine Infektion mit Giardia duodenalis nachgewiesen. Dieses ist die erste Beschreibung einer Ko-Infektion mit M. avium subsp. hominissuis und Giardia duodenalis bei einem Chinchilla. Beide Erreger können ein mögliches Gesundheitsrisiko insbesondere für junge oder immunsupprimierte Personen darstellen, besonders wenn infizierte Tiere eine unspezifische klinische Symptomatik zeigen
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
as a recessive functional variant for hepatic fibrinogen storage disease in Wagyu cattle
Full text linkHepatic fibrinogen storage disease (HFSD) was diagnosed in a 5-month-old Wagyu calf with a history of recurrent respiratory disease. It was characterized by lethargy, dehydration, acidemia, and increased liver enzyme activities. Histologically, disseminated hepatocytes were swollen and showed a single, sharply demarcated, faintly eosinophilic cytoplasmic inclusion with a ground-glass appearance, with the nucleus in an eccentric position. Cytoplasmic inclusions did not stain with the periodic acid-Schiff (PAS) reaction. Using a rabbit polyclonal antibody against fibrinogen, the cytoplasmic vacuoles in the hepatocytes stained intensely. Electron microscopy disclosed hepatocytes with membrane-bound cytoplasmic inclusions filled with fine granular material interspersed with a few coarse-grained electron-dense granules. A trio whole-genome sequencing approach identified a deleterious homozygous missense variant in DGKG (p.Thr721Ile). The allele frequency in 209 genotyped Wagyu was 7.2%. This is a report of a DGKG-related recessive inherited disorder in cattle and adds DGKG to the list of candidate genes for HFSD in other species
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