196,700 research outputs found
R. Wirz s/m R. Rahn z. f. E
No full textDedikationssilhouette nach links von R. Wirz, gewidmet Johann Rudolf Rahn (1841-1912)Anonyme/r Künstler/inDatierung gemäss Rahns Notizen im vorangestellten alphabetischen NamensregisterHandschriftliche Widmung unterhalb des Porträts "R. Wirz s[eine]m R. Rahn z[ur] f[reundlichen] E[rinnerung]
De Ementito in omnibus Fidei dogmatibus Romanæ Ecclesiæ Doctorum Consensu, Ex occasione famosissimarum Propositionum Janseniticarum
No full textAdjuvante Christi Gratia, Praeside Joanne Wirtzio ... ; Respondente Conrado Wirtzio ... ; Assumente Joh. Heinrico Heideggero ... Disputabitur Postridie Synodi Autumnalis, M DC LII.Widmungsgedicht von Johannes Wirz an Joh. Conrad Werdmüller auf dem Titelblatt verso. Gedichte von Conrad Wirz und Johann Heinrich Heidegger auf Bl. C₄.Dissertation Hohe Schule Zürich 165
Enucleatio Insignis Dicti Salvatoris Joh. XIV. 6
No full text... ad placidam disputationem proposita, A Johanne Wirtzio ... ; Respondente Henrico Ernio, V.D. Ministro ; Assumente Casparo Wyssio, ... Postridie Synodi Autumnalis, Anno M DC LII.Diss. Hohe Schule Zürich, 1652Widmungsgedicht von Johannes Wirz an Johannes Berger auf dem Titelbl. vers
Circadian and homeostatic modulation of sleep spindles in the human electroencephalogram
No full textSleep spindles are transient EEG oscillations of about 12-16 Hz. Together with slow waves, they hallmark the human non-REM sleep EEG. Sleep spindles originate in the thalamus and are suggested to have a sleep protective function by reducing sensory transmission to the cortex. Other evidence points to an involvement of sleep spindles in brain plasticity processes during sleep. Previous studies have shown that sleep spindles are both under homeostatic (sleep-wake dependent) and circadian (time of day-dependent) control. Furthermore, frequency-specific topographical distribution of power density within the spindle frequency range has been reported. The aim of this thesis was to assess homeostatic and circadian influences on spectral spindle frequency activity (SFA) and spindle parameters in different brain regions. Healthy young volunteers participated in both a 40-h sleep deprivation (SD) and a 40-h multiple nap paradigm. The recovery nights after the SD and the nap protocol served to assess the effect of enhanced and reduced homeostatic sleep pressure, respectively. The multiple nap paradigm revealed the modulation of sleep spindles across the circadian cycle. Two different methodological approaches were used to analyze the EEGs: classical spectral analysis (Fast Fourier Transform, FFT) and a new method for instantaneous spectral analysis (Fast Time Frequency Transform, FTFT), developed as a part of this thesis project in collaboration with Wim Martens from TEMEC, The Netherlands. Slow wave activity (SWA, spectral power density in the 0.75-4.5 Hz range) and spindle frequency activity (SFA, spectral power density in the spindle frequency range) in the high frequency range (13.75-16.5 Hz) were oppositely affected by the differential levels of sleep pressure (Chapter 2). These effects strongly depended on brain location. After SD, the SWA increase compared to the baseline night was most pronounced in the beginning of the night and in the fronto-central region. Power density in the high spindle frequency range was reduced in the centro-parietal brain region. After the nap protocol, when sleep pressure was reduced, power density in the SWA range was decreased at the beginning of the night. SFA was generally increased after the nap protocol. The data indicate that the balance between SWA and high-frequency spindle activity may represent a sensitive marker for the level of
homeostatic sleep pressure.
The new method of FTFT revealed that spindle density was reduced after SD
(Chapter 3). This reduction was particularly apparent in the frontal derivation, and
most pronounced in the first half of the night. The reduction of spindle density with its
temporal and local specificity confirms the inverse homeostatic regulation of slow
waves and sleep spindles. Sleep spindles had a lower frequency and a higher
amplitude after SD. Within an individual spindle, frequency variability was reduced,
which indicates that sleep spindles were more stable and homogenous after SD. The
increase in spindle amplitude and the reduced intra-spindle frequency variability
suggests a higher degree of synchronization in thalamocortical neurons under high
homeostatic sleep pressure.
EEGs during the nap paradigm were analyzed to compare SFA and sleep
spindle characteristics during and outside the circadian phase of melatonin secretion
(the “biological night” and “biological day”, respectively) (Chapter 4). In naps
occurring during the phase of melatonin secretion, lower spindle frequencies were
promoted, indexed as a reduction in mean spindle frequency (i.e. slowing of sleep
spindles) and an increase in spindle amplitude and SFA in the low-frequency range
(up to ~14.25 Hz) paralleled by a reduction in the high-frequency range (~ 14.5-16
Hz). Furthermore, spindle density was increased, and intra-spindle frequency
variability reduced during the night. Thus, the circadian pacemaker is likely to
promote low-frequency, high amplitude and homogenous sleep spindles during the
biological night. The circadian modulation of sleep spindles may be a way by which
the circadian system modulates and times sleep consolidation. This circadian
modulation clearly depended on brain location such that it was maximal in the
parietal and minimal in the frontal derivation.
Taken together, the segregated analysis of different spindle parameters by the
new high-time and high-frequency resolution spindle analysis provides new insights
into sleep spindles and their regulation. Both homeostatic and circadian processes
affected sleep spindles characteristics in a topography-specific manner. These statedependent
local aspects provide further evidence that sleep is a dynamic
phenomenon which reflects use-dependent recovery or reactivation processes
Euphemismi in nuptias reverendi & doctissimi viri Dn. Iosiae Waseri, ... cum lectissima & honestissima virgine Margareta Kellera, amplissimi viri Dn. Ioh. Conradi Kelleri ... filia : ad d. VII. Iun. anno M. DC. XXIIII
No full textDruckermarkeEnthält Hochzeitsgedichte von Johannes Wirz, Felix Wyss, Joh. Rudolf Stucki, Joh. Felix Koller, Vinzenz Paravicini und Rudolf Wase
Perioperative analgesia with nonopioid analgesics
No full textHintergrund
Nichtopioidanalgetika werden bei vielen Patienten zur perioperativen Analgesie eingesetzt. Zu einigen praktischen Fragen beim Einsatz von Nichtopioidanalgetika liegen z. T. nur wenig Informationen aus Studien vor, und in Krankenhäusern existieren häufig keine Konzepte zum Vorgehen, z. B. zur Patientenaufklärung und zum Zeitpunkt der perioperativen Gabe.
Methodik
Eine Expertengruppe der beteiligten Fachgesellschaften hat konsensbasierte Empfehlungen zum perioperativen Einsatz von Nichtopioidanalgetika erarbeitet und in einem strukturierten formalen Konsensusprozess verabschiedet.
Ergebnisse
Die Arbeitsgruppe stimmt überein, dass Nichtopioidanalgetika Bestandteil eines perioperativen multimodalen Analgesiekonzepts sein sollen und Patienten präoperativ über Nutzen, Risiken und alternative Behandlungsmöglichkeiten aufgeklärt werden sollen. Die präoperative Patienteninformation und -edukation soll auch eine Schmerz- und Analgetikaanamnese umfassen und Patienten mit Risikofaktoren für starke Schmerzen und eine Schmerzchronifizierung sollen identifiziert werden. Unter Berücksichtigung von Kontraindikationen können Nichtopioidanalgetika abhängig von der Operationsdauer auch schon prä- oder intraoperativ gegeben werden, um nach Beendigung der Anästhesie ausreichende Plasmakonzentrationen zu erzielen. Nichtopioidanalgetika oder Kombinationen von (Nichtopioid‑)Analgetika sollen nur für einen begrenzten Zeitraum gegeben werden. Ein gemeinsam erarbeiteter abteilungsübergreifender Behandlungsstandard mit dem Nichtopioidanalgetikum erster Wahl, weiteren Therapieoptionen sowie adäquaten Dosierungen, ergänzt durch eingriffsspezifische Konzepte, soll schriftlich hinterlegt werden. Bei Entlassung aus dem Krankenhaus soll der nachbehandelnde Arzt zu perioperativ gegebenen und aktuell noch eingenommenen Analgetika schriftliche Informationen erhalten. Patienten sollen zu möglichen Nebenwirkungen der Analgetika und ihrer Symptome, die auch nach Krankenhausentlassung auftreten können, und die befristete Einnahmedauer informiert werden
Feeding difficulties in disabled children leads to malnutrition: experience in an Indian slum
No full textCatalogue de tableaux anciens..., formant la collection de M. H. Wirz,... Tableaux anciens, dessins, aquarelles et gouaches dépendant de la collection de M. X... / [expert] E. Féral
No full text[Vente. Art. 1888-04-09. Paris][Collection. Art. Wirz, H.. 1888]Référence bibliographique : Lugt, 47250Appartient à l’ensemble documentaire : VenteEST2Avec mode text
Novelty in phylogeny of gastrotricha: evidence from 18S rRNA gene
No full textGastrotricha form a phylum which is crucial for
defining the origin of pseudocoelomates, in that they
share a number of characters with Rotifera and Nema-
toda but also with acoelomates, and even the evolution-
ary relationships within the phylum are anything but
defined. For this reason the first extensive molecular
data on Gastrotricha from the 18S rRNA sequences of
both orders have been obtained and analyzed. Se-
quence analyses show that the phylum Gastrotricha is
strictly monophyletic along an evolutionary line quite
distinct from that of both Rotifera and Nematoda. A
new view of the evolutionary history of the phylum
Gastrotricha is put forward, in which Chaetonotida,
and not Macrodasyida, are the most primitive forms of
the group, contrary to the commonly held view. A
polyphyletic origin of aschelminthes is supported, and
the misleading term pseudocoelomates should be
discarded
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