1,617 research outputs found
Data for "Effects of fibroblast growth factor 2 on muscle precursor cells from mouse limb and extraocular muscle"
No full textFibroblast growth factor 2 (FGF2) is known to play a role in skeletal muscle development and growth. We examined two populations of myogenic precursor cells for their responses to FGF2 in vitro using both extraocular and limb skeletal muscle. Fluorescence-activated cell sorting (FACS) was used to isolate two different populations of myogenic precursor cells, the EECD34 cells (positive for CD34, and negative for Sca1, CD31, and CD45) and PAX7-positive cells, from tibialis anterior and extraocular muscles of mice. These cells were cultured and treated with either proliferation or differentiation media in the absence or the presence of FGF2, followed by assays to determine the effects on proliferation and differentiation. EECD34 cells and PAX7-positive cells from both muscles responded to FGF2 with significantly increased proliferation. Both myogenic precursor cell populations from each muscle type showed increased percentage of desmin-positive mononucleated cells, but decreased rates of fusion into multinucleated myotubes in the presence of FGF2 in this in vitro system relative to control cells. FGF2 has pleiotropic effects on skeletal muscles. Contrary to the literature, FGF2 did not inhibit differentiation, but did appear to decrease fusion into multinucleated myofibers in vitro. Examination of immunostaining for myomerger in differentiating PAX7-positive cells in the presence or absence of FGF2 demonstrated a significant reduction of expression in the presence of elevated FGF2 levels. These results provide a potential mechanism for reduction in myofiber number and size in the extraocular muscles in individuals with Apert syndrome, where FGF receptor 2 mutations maintain the receptor in an activated state resulting in significantly reduced myofiber size.National Eye Institute RO1EY15313
National Science Foundation NRT-UtB: Graduate Training Program in Sensory Science
National Eye Institute NIHT32EY025187
Minnesota Lions Gift of SightWinker, Austin J; Johnson, Laura L; Jadhav, Ria; Nguyen, Catherine; Hitch, Elizabeth; McLoon, Linda K. (2025). Data for "Effects of fibroblast growth factor 2 on muscle precursor cells from mouse limb and extraocular muscle". Retrieved from the Data Repository for the University of Minnesota (DRUM), https://doi.org/10.13020/VR2S-3739
Staging the life-world: Habermas and the recuperation of Austin speech act theory
No full textPT: J; CR: APEL KO, 1976, SPRACHPRAGMATIK PHIL AUSTIN JL, 1962, HOW TO DO THINGS WOR AUSTIN JL, 1970, PHILOS PAPERS CULLER J, 1982, DECONSTRUCTION DERRIDA J, 1977, GLYPH, V1 ECO U, 1992, UNDERSTANDING ORIGIN, P273 FISH S, 1987, TRACING LIT THEORY HABERMAS J, 1984, THEORY COMMUNICATIVE, V1 HABERMAS J, 1987, THEORY COMMUNICATIVE, V2 HABERMAS J, 1989, JURGEN HABERMAS SOC MARTINET A, 1962, FUNCTIONAL VIEW LANG, P24 QUINE WV, 1960, WORD OBJECT SEARLE JR, 1969, SPEECH ACTS SEARLE JR, 1977, GLYPH, V1 VANEEMEREN F, 1983, SPEECH ACTS ARGUMENT WARNOCK GJ, 1989, FL AUSTIN; NR: 16; TC: 0; J9: J THEOR SOC BEHAV; PG: 12; GA: KR147Source type: Electronic(1
The Bibliographic Concept of Work in Cataloguing and its Issues
No full textThis report explores the IFLA’s document Functional Requirements for Bibliographic Records (FRBR). It discusses the notion of work in cataloguing as it was built since the 1950s, inasmuch this notion constitutes the conceptual framework for the proposal. Also, the entity-relationship database modeling (ERDM) system is described as far as such model provides to FRBR the operative elements that make it functional. ERDM gives to FRBR a user-centered approach as well. In its third chapter, the report tests the FRBR model through its application to a set of items belonging to the novel Rayuela, by Julio Cortázar, held at the Benson Latin American Collection of the University of Texas at Austin. Finally, some critical issues are raised along with general conclusions regarding the functionality of the mode
Sisurcana recurvana Austin & Dombroskie 2020, new
No full textSisurcana recurvana (Zeller), new combination (Figs. 8, 13, 19) Tortrix recurvana Zeller, 1866: 143 Cacoecia recurvana: [unknown author, date] (new combination). “ Archips ” recurvana: Powell et al. 1995: 148 (new combination). [Archipini unplaced] recurvana: Brown 2005: 124. Type material.— Tortrix recurvana Zeller, 1866: Lectotype, ♀: COLOMBIA: EX. 66,173 f.5., Zeller Coll., Walsingham Collection, 1910-427, 102210 [examined]. B[ritish] M[useum] Genitalia slide #7851, Razowski genitalia slide #5361 [examined] (BMNH). Discussion.—Zeller described Tortrix recurvana from two females, but it is unclear who designated the female that we figure (Fig. 8) as the lectotype. Powell (1986) commented on this species in his description of Sisurcana, but refrained from transferring it to that genus. Tortrix recurvana is extremely similar in forewing pattern (Fig. 8) and in genitalia to Sisurcana sanguinoventer Razowski and Wojtusiak, 2010. However, the cestum in T. recurvana terminates before the corpus bursae (Fig. 19), but not in S. sanguinoventer. We examined a third female specimen from the BMNH collected in Peru (KAA diss. #0135), which looks like a smaller version of T. recurvana, but the apophyses are noticeably longer. It may represent an undescribed species. Based on similarities between T. recurvana and S. sanguinoventer, we transfer T. recurvana to Sisurcana. Males of both of these species are unknown, but may be described and simply unassociated because of the extreme sexual dimorphism in Atteriini.Published as part of Austin, Kyhl A. & Dombroskie, Jason J., 2020, New Combinations In Neotropical Archipini And Atteriini (Lepidoptera: Tortricidae: Tortricinae), With The Description Of A New Genus, pp. 1-11 in Proceedings of the Entomological Society of Washington 122 (1) on page 8, DOI: 10.4289/0013-8797.122.1.1In, http://zenodo.org/record/372476
J. Frank Dobie of Austin with Mrs. Amon G. Carter Junior at the Amon Carter Museum of Western Art
No full textJ. Frank Dobie of Austin, a noted Texas author and Mrs. Amon G. Carter Junior having a conversation at the opening of the exhibition. They are pictured with a huge book in their hands discussing over the Charles Russell\u27s letters at the Amon Carter Museum of Western Art. Fort Worth Star-Telegram Evening edition January 25, 1962.https://mavmatrix.uta.edu/specialcollections_startelegram1960s/1727/thumbnail.jp
The construction of Karen Karnak: The multi-author-function
No full textThis thesis is situated within the comparatively recent developments of Web 2.0 and the emergence of interactive WikiMedia, and explores the mode of authorship within a Read/Write culture compared to that of a Read/Only tradition. The hypothesis of this study is that the role of the audience has become merged with the author, and as such, represents new functions and attributes, distinct from a more conventional concept of authorship, in which the roles of audience and author are more separate. Read/Write and participatory culture, as defined by this study, is focused on collaboration, and includes the influences of D.I.Y. culture, Open-Source practices and the production of text by multiple authors. Multi-authorship presents a re-thinking of several concepts which support the notion of the individual author, since the focus of multi-authorship is not on attribution and ownership of a finished text, but on the continued malleability of a text. Modes of multi-authorship, demonstrated in the use of the pseudonyms Alan Smithee and Karen Eliot, represent declarative authors whose names signify multiple origins, whilst concurrently indicating a distinct body of work. The function of these names form an important context to this study, since primary research involves the construction of an experimental mode of multi-authorship utilising WikiMedia technology and the interaction of thirty nine participants, who are invited to create a body of work under the collective pseudonym Karen Karnak. The data generated by this experiment is analysed using aspects of Michel Foucault's author-function to identify and determine power structures inherent in the WikiMedia context. The interplay of power structures, including concepts such as identity, ownership and the body of work, affect the resulting mode of authorship and contribute to the construction of Karen Karnak, suggesting further areas of research into the emerging multi-author
Distribution of seasonal ponded areas on geomorphic surfaces of selected east-west transects of the Willamette Valley: final report, 1993-1994
No full textJ. Herbert Huddleston (Ph D., Extension Specialist, Soil Science Department, Oregon State University), Will Austin (Research Assistant, Soil Science Department, Oregon State University) ; submitted to Oregon State Division Of Lands.Title from PDF cover (viewed on April 29, 2020)."Completed June 29, 1994."This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Mode of access: Internet from the Oregon Government Publications Collection.Text in English
Shadowgraphy of the end-effects regime produced by clustered rockets
No full textThe plume produced by a cluster of two high area-ratio thrust optimized parabolic contour nozzles is visualized by way of retroreflective shadowgraphy. Both steady and transient operations of the nozzles (start-up and shut-down) were conducted in the anechoic chamber and high speed flow facility at The University of Texas at Austin. Both nozzles exhibit free shock separated flow, restricted shock separated flow and an end-effects-regime prior to flowing full. Radon transforms of the shadowgraphy images are used to identify the locations in the flow where sound waves are being generated. During these off design operations of the nozzles, most sound waves are generated by turbulence interactions with the shock cells located in the supersonic annular plume. During the end-effects-regime, this supersonic annular plume is shown to flap violently, thus providing a first principals understanding of the sources of most intense loads during engine ignition
Design and statistical analysis of observational studies
No full text[No abstract available]Austin PC, 2008, STAT MED, V27, P2037, DOI 10.1002-sim.3150; Awwad J, 2012, BJOG-INT J OBSTET GY, V119, P1379, DOI 10.1111-j.1471-0528.2012.03438.x; Hansen BB, 2008, STAT MED, V27, P2050, DOI 10.1002-sim.3208; Hill J, 2008, STAT MED, V27, P2055, DOI 10.1002-sim.3245; Stuart EA, 2008, STAT MED, V27, P2062, DOI 10.1002-sim.32070
Pursuing History: The Joys and Hazards of Following All the Stories of the Past
No full textMemoirs of Ernest (Ern) J. Dick, historian and archivist. Ern worked at the CBC Archives, has many connections with the Nova Scotia historical community, and developed the "Moving Images of Atlantic Canada’" course at Saint Mary's University. He is also the author of "Silver Hair and Golden Voice - Austin Willis from Halifax to Hollywood", published by Nimbus in 2020
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