8,263 research outputs found
Advanced PC architecture.
No full textThe first book ever to give a complete picture of the workings of a PC! A comprehensive guide to the component systems of the PC, this book provides a foundation to the understanding of previous, current and future PC systems, and how the specification of each component of a PC affects the overall system performance. The book outlines each of the main PC processors and contrasts their performance. It also examines each of the main interface devices and shows how they integrate into the main systems. If you are an undergraduate or professional looking for a complete understanding of the internal architecture of the PC, and how it is changing, this book is for you. It explains how systems have evolved from the original PC, keeping its compatibility with previous systems, whilst increasing its power. It also provides an insight into how the PC will evolve in the future. Key chapters: * Motherboards - Analyses typical motherboards and shows how each of the components interfaces together, and how the architecture affects the system performance. * Memory - Shows how chache memory and DRAM memory interface to the system and the processor. * PCI bus - Discusses the fundamentals of the PCI bus and shows its importance in the architecture of modern PCs. * On-line multiple choice tests for students * On-line PowerPoint/HTML slides of all the graphics from the book
A PC parallel port button box provides millisecond response time accuracy under Linux
No full textFor psychologists, it is sometimes necessary to measure people's reaction times to the nearest millisecond. This article describes how to use the PC parallel port to receive signals from a button box to achieve millisecond response time accuracy. The workings of the parallel port, the corresponding port addresses, and a simple Linux program for controlling the port are described. A test of the speed and reliability of button box signal detection is reported. If the reader is moderately familiar with Linux, this article should provide sufficient instruction for him or her to build and test his or her own parallel port button box. This article also describes how the parallel port could be used to control an external apparatus
Environmental (waste) compliance control systems for UK SMEs
No full textWhile the ‘environment’ is often perceived as a heavily regulated area of business, in reality, directly-regulated businesses represent a small proportion of the business community. This study aimed to evaluate and outline potential improvements to compliance controls for small and medium-sized enterprises (SMEs), particularly those involved in the waste sector. Forty-four SMEs from England were interviewed/audited between April-September 2008. Using a UK-based system as a case-in-point, the Environment Agency’s (EA) Operational Risk Appraisal (‘Opra’)/Compliance Assessment Report (CAR) system was analysed. Environmental compliance performance indicators and an initial assessment methodology for SMEs were developed. The study showed:• Compliance with permitting legislation was poor in many areas.• Regulatory authorities are either unable/failing to implement their enforcement policies or unable/failing to identify non-compliances due to the infrequency or limited nature of their inspections.• Improvements are needed to the EA Opra/CAR system – control measures are not fully taken into account when calculating risk.Recommendations to improve SME compliance controls include using internationally applicable general and specific compliance and non-compliance performance indicators, re-designing the Opra system and using an initial assessment methodology based on understanding the hazardousness of SME categories, compliance levels and operator competency.<br/
Further Characterization of Dopamine Release by Permeabilized PC 12 Cells
No full textRat pheochromocytoma cells (PC 12) permeabilized with staphylococcal α-toxin release [3H]dopamine after addition of micromolar Ca2+. This does not require additional Mg2+-ATP (in contrast to bovine adrenal medullary chromaffin cells). We also observed Ca2+-dependent [3H]-dopamine release from digitonin-permeabilized PC 12 cells. Permeabilization with α-toxin or digitonin and stimulation of the cells were done consecutively to wash out endogenous Mg2+-ATP. During permeabilization, ATP was removed effectively from the cytoplasm by both agents but the cells released [3H]dopamine in response to micromolar Ca2+ alone. Replacement by chloride of glutamate, which could sustain mitochondrial ATP production in permeabilized cells, does not significantly alter catecholamine release induced by Ca2+. However, Mg2+ without ATP augments the Ca2+-induced release. The release was unaltered by thiol-, hydroxyl-, or calmodulin-interfering substances. Thus Mg2+-ATP, calmodulin, or proteins containing -SH or -OH groups are not necessary for exocytosis in permeabilized PC 12 cells
Lord Harold Wilson
No full textJames Harold Wilson, Baron Wilson of Rievaulx, KG, OBE, PC, FRS, FSS (11 March 1916 – 24 May 1995) was a British politician who served as Prime Minister of the United Kingdom twice, from October 1964 to June 1970, and again from March 1974 to April 1976. Wilson was the Leader of the Labour Party from 1963 to 1976, and was a Member of Parliament (MP) from 1945 to 1983. Wilson is the only Labour leader to have formed Labour administrations following four general elections (one as a minority government).
Wikipediahttps://nsuworks.nova.edu/nsudigital_forums/1131/thumbnail.jp
Millisecond accuracy video display using OpenGL under Linux
No full textTo measure people’s reaction times to the nearest millisecond, it is necessary to know exactly when
a stimulus is displayed. This article describes how to display stimuli with millisecond accuracy on a
normal CRT monitor, using a PC running Linux. A simple C program is presented to illustrate how this
may be done within X Windows using the OpenGL rendering system. A test of this system is reported
that demonstrates that stimuli may be consistently displayed with millisecond accuracy. An algorithm
is presented that allows the exact time of stimulus presentation to be deduced, even if there are relatively
large errors in measuring the display time
Frontmatter (Titlepage, Table of Contents, Author List, PC List, Reviewer List)
No full textFront matter including table of contents, author list, PC list, and reviewer list
New computer in Mount Wilson
No full textThe PC in Mount Wilson had failed. A replacement was built in Birmingham and installed on this trip. A new UPS and mains controller were installed. The effect of the primary mirror position on beam alignment was investigated
The molecular genetic analysis of the expanding pachyonychia congenita case collection
No full textBackgroundPachyonychia congenita (PC) is a rare autosomal dominant keratinizing disorder characterized by severe, painful, palmoplantar keratoderma (PPK) and nail dystrophy, often accompanied by oral leukokeratosis, cysts and follicular keratosis. It is caused by mutations in one of five keratin genes; KRT6A, KRT6B, KRT6C, KRT16 or KRT17.ObjectivesTo identify mutations in 84 new families with a clinical diagnosis of PC, recruited by the International Pachyonychia Congenita Research Registry (IPCRR) during the last few years.MethodsGenomic DNA isolated from saliva or peripheral blood leukocytes was amplified using primers specific for the PC associated keratin genes and PCR products were directly sequenced.ResultsMutations were identified in 84 families in the PC-associated keratin genes, comprising 46 distinct keratin mutations. Fourteen were previously unreported mutations, bringing the total number of different keratin mutations associated with PC to 105.ConclusionsThis study has confirmed at the molecular level the clinical diagnosis of PC in these families, by identifying mutations in KRT6A, KRT6B, KRT6C, KRT16 or KRT17.</p
Subspecies and Distribution. P. c. culpaeus Molina, 1782 — W & C Argentina and C Chile. P. ¢. andinus Thomas, 1914 — altiplano of Bolivia, N Chile, and Peru. Pc. lycoides Philippi, 1895 — Tierra del Fuego. Pc. magellanicus Gray, 1837 — Argentina and S Chile. P. c. reissu Hilzheimer, 1906 — Ecuadorian Andes and extreme S Colombia (Narino). P. c. smithersi Thomas, 1914 — Argentina (Cordoba Mts). in Canidae
No full textSubspecies and Distribution. P. c. culpaeus Molina, 1782 — W & C Argentina and C Chile. P. ¢. andinus Thomas, 1914 — altiplano of Bolivia, N Chile, and Peru. Pc. lycoides Philippi, 1895 — Tierra del Fuego. Pc. magellanicus Gray, 1837 — Argentina and S Chile. P. c. reissu Hilzheimer, 1906 — Ecuadorian Andes and extreme S Colombia (Narino). P. c. smithersi Thomas, 1914 — Argentina (Cordoba Mts).Published as part of Don E. Wilson & Russell A. Mittermeier, 2009, Canidae, pp. 352-446 in Handbook of the Mammals of the World – Volume 1 Carnivores, Barcelona :Lynx Edicions on page 429, DOI: 10.5281/zenodo.566191
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